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Copyright of Quintessenz Zahnmedizin is the property of Quintessenz Verlags GmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A recent study conducted at University Hospital Essen in Germany suggests that dopamine may not play a significant role in the placebo effect for pain relief. The placebo effect occurs when medical symptoms are alleviated through the power of expectation. In the study, participants were asked to apply two creams to their arms before experiencing mild discomfort. Their dopamine levels were manipulated, but this did not seem to affect their perception of pain or their anticipation of pain. The researchers suggest that opioids, cannabinoids, and hormones like oxytocin and noradrenaline may play a role in the placebo effect. However, the context and social factors surrounding treatment are likely more influential than dopamine. [Extracted from the article]

The article presents interview with key figures, including Minnesota Medicine, Senator Kelly L. Morrison, Medical Doctor, Representative Robert Bierman, and a family physician Kim Tjaden. It mentions the implications of a South Dakota company like Sanford Health taking over, the need for a thorough examination by the governor's healthcare task force, and the importance of maintaining the University's role in healthcare for Minnesota's future.

Copyright of Quintessenz Zahnmedizin is the property of Quintessenz Verlags GmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article titled "Feedback" discusses various topics. It begins by mentioning a study conducted at Ulm University Hospital in Germany, which evaluates 16 years of New Year's Eve celebrations in the otorhinolaryngology department. The study reveals that pyrotechnics are a long-standing tradition during this time, with a majority of emergency presentations being related to fireworks injuries and violent altercations. The article also discusses a study on wild geese, which shows that they fly further and higher on New Year's Eve due to the effects of fireworks. Additionally, the article explores the title of an old book called "Heraldry of Fish," which raises questions about whether it refers to drawings of fish or actual fish being carried by people. Lastly, the article mentions a reader who claims to have the ability to identify callers before the phone rings, which is considered a trivial superpower. [Extracted from the article]

The article reports on a study from Stevens Institute of Technology revealing that doctors often judge patients negatively for holding incorrect health beliefs, which could hinder effective communication and care. Topics discussed include the impact of perceived judgment on patient disclosure, the need for medical professionals to address biases, and initiatives by healthcare institutions to improve communication and empathy.

Case name:Stein v. University Hospitals Cleveland Medical Center, No. 1:20‐cv‐00998 (N.D. Ohio 03/29/24). [ABSTRACT FROM AUTHOR]

Case name:Stein v. University Hospitals Cleveland Medical Center, No. 1:20‐cv‐00998 (N.D. Ohio 03/29/24). [ABSTRACT FROM AUTHOR]

Copyright of Quintessenz Zahnmedizin is the property of Quintessenz Verlags GmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The Biomechanics Institute (IBV) has developed the AI3cord project in collaboration with MySphera, S2 Grupo, and the Research Foundation of the General University Hospital of Valencia. This project uses IoT devices and Artificial Intelligence to remotely and non-intrusively evaluate indicators of frailty in older people. During a demonstrative study with 23 participants over 60 years old, data was collected on their physical, cognitive, social, emotional, nutritional, and rest states. The platform was positively evaluated by the participants and has the potential to be applied in the monitoring and prevention of other chronic diseases. [Extracted from the article]

Almost every leader in every sector is now dealing with angry stakeholders. Even a revered company like Apple can find itself suddenly managing outrage flashpoints, both with employees and with external groups. Such encounters are nothing new; what sets this time apart is a perfect storm of three forces: (1) Many people feel unhopeful about the future. (2) Many feel, rightly or wrongly, that the game has been rigged against them. (3) Many are being drawn toward ideologies that legitimize an us-versus-them approach. The author offers a five-step framework for dealing with outrage that draws on analytical insights from disciplines as wide-ranging as the science of aggression, managerial economics, organizational behavior, and political philosophy. It forms the basis of a course he teaches at Oxford and has been built inductively through a series of deep-dive case studies on a variety of organizations, including IKEA, the London Metropolitan Police, Nestlé, and Oxford University Hospitals. [ABSTRACT FROM AUTHOR]

The article lists the top hospitals of Georgia in 2022 including the Emory University Hospital, Wellstar Atlanta Medical Center and the Augusta University Medical Center.

Copyright of Quintessenz Zahnmedizin is the property of Quintessenz Verlags GmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Researchers at Dexeus University Hospital in Barcelona, Spain, have highlighted the importance of musculoskeletal ultrasound (MSUS) in pediatric rheumatology. MSUS is a valuable tool for evaluating pediatric patients with juvenile idiopathic arthritis (JIA) due to its safety, high patient acceptability, and ability to explore multiple joints. The study emphasizes the differences in normal and pathological findings between children and adults assessed by MSUS, providing valuable insights for the management of JIA patients. The research suggests that MSUS may play a significant role in treatment strategies for JIA in the future. [Extracted from the article]

The article discusses a study on intussusception in adult patients, a rare condition often associated with underlying tumors. The research aimed to identify imaging features that could predict tumor-related intussusception. Key findings include that colocolic intussusception is more frequently associated with malignancy, with adenocarcinoma being the most common type of tumor. The study suggests active surveillance for asymptomatic cases and surgical intervention for symptomatic patients, with specific imaging features guiding treatment strategies. [Extracted from the article]

Researchers from the University of Maryland Hospital conducted a study to assess the adherence of practicing allergists in North America to sterility guidelines when testing for bronchodilator responsiveness. The study found that while the majority of allergists used common bronchodilator administration techniques, a significant portion did not consider their techniques to be sterile. The researchers concluded that promoting guideline awareness and proposing updated guidelines focused on common administration techniques is essential to increase adherence to sterility measures among allergists in North America. [Extracted from the article]

A recent study from the First Affiliated Hospital of Henan University of Chinese Medicine in China highlights the importance of monitoring cirrhotic liver nodules for potential malignant transformation into hepatocellular carcinoma (HCC). The research emphasizes the need for sensitive and efficient methods to assess the risk of malignant transformation in cirrhotic nodules, as routine liver biopsies and imaging techniques may not always be suitable. Developing serum biomarkers and a multi-index evaluation model could offer a more convenient and effective approach to monitoring pathological changes in cirrhotic nodules. For more information, the full article can be accessed for free at the provided link. [Extracted from the article]

Researchers at Ibn Sina University Hospital reported a rare case of a 52-year-old man diagnosed with both retroperitoneal liposarcoma and gastric adenocarcinoma, marking only the second reported case worldwide. The simultaneous occurrence of these two malignancies is extremely uncommon, with liposarcoma being a rare malignancy arising from adipose tissue and gastric adenocarcinoma being one of the most common neoplasms globally. This research sheds light on the potential for multiple primary malignancies to occur synchronously in adults, highlighting the importance of further study in this area. [Extracted from the article]

A recent report from Ghent University Hospital discusses the role of uremic toxins in the development of uremic syndrome during chronic kidney disease (CKD) progression. The research emphasizes the need for alternative methods to counteract uremic toxicity, focusing on preserving kidney function, preventing cardiovascular damage, and exploring pharmacologic interventions. The study also reviews options for extracorporeal uremic toxin removal, aiming to develop a more sustainable treatment model for CKD in the future. [Extracted from the article]

A recent study conducted at Qilu Hospital of Shandong University focused on the impact of using a three-dimensional (3D)-printed guide plate for percutaneous pedicle screw implantation in minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) surgery. The study, which included 162 patients, compared outcomes between a conventional group and a 3D printing group. Results showed that the 3D printing group experienced better back pain relief, improved function recovery, and reduced procedure times compared to the conventional group. This research suggests that the use of 3D-printed guide plates can enhance surgical outcomes in orthopedic procedures. [Extracted from the article]

A recent study conducted at a Spanish tertiary hospital focused on assessing the achievement of textbook outcomes (TO) in patients undergoing liver and pancreatic surgery. The study found that TO was achieved in 56.2% of patients, with significant differences noted based on the type of procedure and the expected risk of morbidity and mortality. The researchers concluded that TO is a valuable tool for evaluating postoperative results in hepatopancreatobiliary surgery units. For more information, the full article can be accessed through the Journal of Clinical Medicine. [Extracted from the article]

Researchers at University Hospital Schleswig-Holstein in Germany have developed a novel technique called pull-through endoscopic vacuum-assisted closure therapy for complicated leaks of the gastrointestinal tract. This technique involves a combined external and endoluminal approach, which was found to be safe and effective in treating patients with challenging post-surgical leaks of the upper GI tract. The study included 7 patients between 2021 and 2023, with a median duration of therapy of 30 days and a 100% technical success rate. One major bleeding complication was reported during the therapy. The research was published in Endoscopy International Open and can be accessed for free online. [Extracted from the article]

A recent study conducted at Geneva University Hospitals focused on the management of post-operative lymphatic leaks using Lipiodol lymphangiography (LL). The study included a systematic literature review and a case series of five patients who underwent LL at the institution. The research found that LL was successful in 77.7% of patients, with a clinical success rate of 80.6%. The study concluded that LL is a safe and effective procedure for diagnosing and treating post-operative central lymphatic lesions. [Extracted from the article]

Researchers at University Hospital Son Espases have discussed their research on facial plastic surgery, specifically focusing on a technique called full anterior scoring otoplasty. This technique aims to correct lop ear deformity, a common congenital malformation, by scoring the anterior side of the cartilage to achieve natural-looking ears with reduced long-term relapses. The study highlights the challenges of traditional posterior scoring techniques and proposes an alternative approach for better outcomes. For more information on this research, readers can refer to the journal article "Full anterior scoring otoplasty" published in Facial Plastic Surgery in 2024. [Extracted from the article]

A recent report from Ibn Sina University Hospital in Rabat, Morocco, discusses the case of a 5-year-old boy with an orbital dermoid cyst, a common type of cystic lesion in children. The research emphasizes the importance of imaging studies in diagnosing and planning the management of such cases. The cyst was successfully removed through surgery, confirming the diagnosis. This study provides valuable insights into the presentation and management of orbital dermoid cysts in pediatric patients. [Extracted from the article]

A study conducted at University Hospital San Carlos in Madrid, Spain, explored the prevalence of genetic susceptibility to celiac disease (CD) and non-celiac gluten sensitivity (NCGS) in female patients with recurrent reproductive failure (RRF). The research found a higher prevalence of HLA alleles associated with CD and NCGS in RRF patients compared to the general population, with significant associations with thyroid disease. The study suggested that a gluten-free diet and levothyroxine treatment could improve pregnancy outcomes in RRF patients with genetic susceptibility to CD/NCGS. [Extracted from the article]

Researchers at Yantai Yuhuangding Hospital in China reported on the first known case of male retroperitoneal mesonephric-like adenocarcinoma, a rare tumor type. The 65-year-old patient presented with lumbar pain and dysuria, with imaging revealing a retroperitoneal tumor. Immunohistochemistry and molecular analysis were conducted, with no clinically significant variants detected. The study highlights the importance of accurate diagnosis for optimal clinical outcomes in cases of this rare tumor. [Extracted from the article]

A recent study conducted at University Hospital Tours examined the impact of bleeding and ischemic complications on mortality after percutaneous coronary interventions (PCI). The study, which included 54,599 patients, found that both types of complications were associated with an increased risk of mortality, with the risk being higher in the early period after the procedure. The research suggests that the risk decreases over time, particularly faster after ischemic complications compared to hemorrhagic events or a combination of both. The findings were published in the European Heart Journal and can be accessed for free online. [Extracted from the article]

A recent study conducted at Osijek University Hospital in Croatia found that the isolation of Candida species in surgical ICU patients was associated with comorbidities, prolonged mechanical ventilation, and higher mortality rates. The research analyzed data from 15,790 microbiological samples and concluded that patients with isolated Candida had a significantly higher mortality rate compared to the control group. The study highlighted the importance of considering comorbidities and sepsis as predictors of mortality in ICU patients with Candida isolation. [Extracted from the article]

A recent study conducted at Aarhus University Hospital focused on healthcare utilization patterns preceding a diagnosis of systemic sclerosis (SSc). The research found that patients with SSc had increased contact with general practice and hospitals in the three years leading up to their diagnosis compared to non-SSc references. This suggests an opportunity for earlier diagnosis and treatment of SSc, potentially reducing irreversible tissue damage. The study highlights the importance of monitoring healthcare utilization trends to improve outcomes for individuals with SSc. [Extracted from the article]

Researchers at Ibn Rochd University Hospital have identified a rare medical condition known as extranodal intraductal papilloma in the axillary supernumerary breast. This condition involves the development of a benign tumor in the ducts of supernumerary breast tissue found in the axilla. A case study of a 70-year-old woman with this condition was reported, with successful surgical treatment and a positive post-treatment outcome. The research was published in Radiology Case Reports and can be accessed for further information. [Extracted from the article]

A recent study conducted by a researcher at Nottingham University Hospitals NHS Foundation Trust focused on the impact of establishing an Upper Limb Orthopaedic Network for arthroplasty cases. The study found that the network discussions led to changes in management plans for over half of the cases discussed, with only a small percentage requiring transfer to a tertiary center. The research concluded that regional network discussions can aid decision-making for complex cases, providing patients with the advantage of regional expertise while being managed conveniently at their local hospital. [Extracted from the article]

A systematic review conducted by Cambridge University Hospitals NHS Foundation Trust examined the outcomes of dual-mobility trapeziometacarpal joint arthroplasties, including various prostheses. The review found improvements in strength, range of motion, pain, function, and satisfaction, with a complication incidence of 13% and a low risk of dislocation. However, due to the limited follow-up period, conclusions about long-term implant survival were not possible, and the review highlighted the need for higher-quality evidence with longer-term follow-up for trapeziometacarpal joint arthroplasty. [Extracted from the article]

A multicenter retrospective study conducted across four hospitals evaluated the feasibility, efficacy, and safety of distal transradial access (dRA) for endovascular treatment of malfunctioning dialysis fistulas. The study compared dRA with conventional access techniques and found similar technical and clinical success rates between the two groups. Distal transradial access was deemed a feasible and effective approach with a low complication profile, particularly beneficial for patients with complex fistulas. The study was conducted by researchers at University Hospital in Catanzaro, Italy, and published in the journal Life. [Extracted from the article]

A report from University Hospital Parc Tauli in Sabadell, Spain, discusses the potential of artificial intelligence (AI) in improving the epidemiology and diagnosis of acute respiratory infections (ARIs). Traditional methods for diagnosing ARIs face limitations in speed, accuracy, and scalability, making AI a promising tool for enhancing early detection and precise diagnosis. The review explores the integration of AI in ARI management, highlighting its current applications and future prospects, while also addressing the challenges that must be overcome to realize its full potential. [Extracted from the article]

A study conducted at the University Hospital examined the sociodemographic characteristics of participants in the Danish Capital Region Health Survey who responded online versus those who used a paper-based questionnaire. The research found that the proportion of paper respondents decreased from 18% in 2017 to 16% in 2021, with women more likely to respond on paper than men. The study highlighted the potential risk of excluding elderly citizens from large population surveys if only web-based response options are provided, emphasizing the importance of considering alternative modes of data collection for representativeness. [Extracted from the article]

Researchers at University Hospital Ulm have highlighted the importance of involving various actors in health research to enhance the relevance and impact of projects and interventions. They propose the Theory of Change (ToC) method as a systematic approach to actively engage actors in the planning, implementation, and evaluation of interventions. By visualizing causal pathways and relationships in a ToC map, this method aims to foster shared understanding, collaboration, and ownership among all involved parties, ultimately leading to increased health benefits from interventions and policies. The study was published in the European Journal of Public Health and can be accessed for free online. [Extracted from the article]

A recent study conducted at University Hospital Leipzig focused on patients with statin intolerance (SI) and its impact on their quality of life. The research found that patients with SI experienced impaired quality of life, with women being more frequently and severely affected. The study identified five clusters of SI patients based on variables predicting severity of pain while on statin therapy, which may help in developing individualized strategies to improve patient outcomes. Overall, the study highlights the need for personalized approaches to address the challenges faced by patients with statin intolerance. [Extracted from the article]

Researchers at Oslo University Hospital have conducted a study on advancing EEG prediction using deep learning and uncertainty estimation in brain informatics. The study explores the potential of deep learning models to predict sex directly from EEG data, aiming to optimize techniques in EEG data analysis. The research found that incorporating uncertainty estimations and using deep ensembles led to increased prediction performance, with the best-performing ensemble achieving 91.1% accuracy in predicting sex from EEG data. The study highlights the importance of incorporating explainability measures in deep learning systems for healthcare applications. [Extracted from the article]

A study conducted by researchers at the University Hospitals Bristol and Weston NHS Foundation Trust addressed deficits in malnutrition care in northern Sierra Leone through an educational intervention. The research aimed to challenge negative cultural perceptions of malnourished patients and increase knowledge of key guidelines among healthcare staff. The two-day training course developed with the support of the World Health Organisation led to improved clinical practice in inpatient feeding units, demonstrating the effectiveness of the intervention. Further research is needed to assess the sustainability of these improvements. [Extracted from the article]

Researchers from the University of Liege have revisited the threshold for secondary mitral regurgitation (MR) severity, focusing on insights from the RESHAPE-HF2 trial. The study challenges the traditional EROA threshold of 0.40 cm2 for intervention, suggesting that earlier intervention may benefit patients with lower EROA. The trial evaluated the use of transcatheter edge-to-edge repair (TEER) in patients with moderate-to-severe secondary MR, showing significant reductions in heart failure hospitalizations and improvements in quality of life, indicating that earlier intervention could improve outcomes for patients with less severe MR. [Extracted from the article]

A study conducted at the University of Colorado Anschutz Medical Campus found that bedside interdisciplinary rounds (BIDR) improve patient and provider satisfaction by promoting trust and collaboration within healthcare teams. BIDR involves the entire healthcare team meeting at the patient's bedside to discuss care plans, allowing for transparent communication and patient involvement. While patients and providers reported positive experiences with BIDR, there were suggestions for improvement, such as using accessible language, clarifying team roles, and addressing input in real time to enhance the process. [Extracted from the article]

The article discusses the use of tumor organoids in personalized medicine, highlighting their potential for personalized tumor therapy and pharmaceutical research. It emphasizes the need for high-throughput solutions to streamline the process of establishing and applying tumor organoid models. The research aims to provide a comprehensive overview of technologies that can optimize the culture and drug screening of tumor organoids to identify more effective tumor therapeutics. [Extracted from the article]

Researchers from the Affiliated Hospital of Qingdao University in China have discovered two novel nanobodies, N14 and N152, that target the Trop2 receptor, disrupting its dimerization and inhibiting tumor cell growth. These nanobodies show high specificity and efficacy in Trop2-positive tumor cells, offering potential as innovative targeted therapeutics. The study highlights the unique binding patterns and anti-tumor effects of N14 and N152, suggesting a promising avenue for pan-cancer therapies. [Extracted from the article]

Researchers from University Hospitals Leuven in Belgium have conducted a study on the use of bacteriophages to treat infections caused by Cutibacterium acnes in patients with periprosthetic joint infection (PJI). The study isolated nine phages with lytic activity from human skin and tested their effectiveness against clinical strains of C. acnes. The phage cocktail showed promising results in reducing bacterial load and disrupting biofilms associated with the infection, suggesting that phage therapy could be a valuable adjunct to traditional antibiotics in treating orthopedic device-related infections. The research was funded by Ao Trauma and published in the journal Viruses. [Extracted from the article]

Researchers at the National University Hospital have provided new insights into urology with a case report on Xanthogranulomatous pyelonephritis successfully treated with antibiotics. Xanthogranulomatous inflammation is a rare benign inflammatory disease that can mimic malignancy, requiring histopathological examination for diagnosis. The case report demonstrated that antibiotics alone can be successful in treating this condition, showing significant improvement and resolution on interval imaging. This research offers valuable information for the treatment of Xanthogranulomatous pyelonephritis and highlights the importance of considering non-surgical options. [Extracted from the article]

Researchers at University Hospital Toulouse conducted a study on the potential benefits of Provinols, a red wine polyphenol extract, in reducing neointimal growth in cholesterol-fed rabbits following angioplasty. The study found that Provinols treatment led to a reduction in intimal growth, thickness, and surface area within the stented area, as well as a decrease in lipid deposition and inflammatory response. The findings suggest that plant-derived polyphenols like Provinols may have therapeutic benefits in preventing restenosis associated with stent placement. The research was supported by the Association of Cardiology of Toulouse, France, and was published in the journal Pharmaceutics. [Extracted from the article]

Researchers at Zhongnan Hospital of Wuhan University conducted a study on the molecular mechanisms of benign prostatic hyperplasia (BPH) and the potential therapeutic effects of Y-27632, a Rho kinase inhibitor. The study found that Y-27632 targeted ROCK1 & ROCK2 expression, inhibiting cell proliferation, fibrosis, and epithelial-mesenchymal transition (EMT) in BPH. This research sheds light on the regulatory effects of ROCK isoforms on prostate cells and suggests the therapeutic potential of Y-27632 in treating BPH. [Extracted from the article]

Researchers at the Affiliated Hospital of Qingdao University in China published a case report in Frontiers in Immunology detailing the transformation of oral undifferentiated carcinoma to sarcomatoid carcinoma in a patient undergoing immune combined targeted therapy. The study highlights the potential of this therapy in reducing tumor burden and expanding surgical options for patients, while also emphasizing the importance of routine pathological assessments to guide personalized treatment strategies. The research underscores the complex alterations in tumor biology that can occur during treatment, urging for a comprehensive approach to optimize patient outcomes. [Extracted from the article]