1. Platelet activity and aspirin efficacy after off-pump compared with on-pump coronary artery bypass surgery: Results from the prospective randomized trial PRAGUE 11-Coronary Artery Bypass and REactivity of Thrombocytes (CABARET)
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Bednar, Frantisek, Osmancik, Pavel, Vanek, Tomas, Mocikova, Heidi, Jares, Martin, Straka, Zbynek, and Widimsky, Petr
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Fluorescein ,Cardiology ,Aspirin ,Coronary artery bypass ,Health - Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2008.03.052 Byline: Frantisek Bednar (a), Pavel Osmancik (b), Tomas Vanek (a), Heidi Mocikova (c), Martin Jares (a), Zbynek Straka (a), Petr Widimsky (b) Abbreviations: ACT, activated clotting time; CABG, coronary artery bypass grafting; CPB, cardiopulmonary bypass; FITC, fluorescein isothiocyanate; MI, myocardial infarction; PRP, platelet-rich plasma Abstract: Changes in hemostasis after off-pump coronary artery bypass grafting are still being discussed. There is a lack of information about platelet activity and aspirin efficacy after coronary artery bypass grafting. The aim of this study was to assess and compare platelet activity and aspirin efficacy early and late after off-pump and on-pump coronary artery bypass grafting. Author Affiliation: (a) Cardiocenter, Department of Cardiac Surgery, 3rd Medical School, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic (b) Cardiocenter, Department of Cardiology, 3rd Medical School, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic (c) Department of Clinical Hematology, 3rd Medical School, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic Article History: Received 20 October 2007; Revised 13 February 2008; Accepted 7 March 2008 Article Note: (footnote) Supported by research grant no. 8526-3/2005 from the Internal Grant Agency of the Ministry of Health of the Czech Republic.
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- 2008