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Cold and ischemia/reperfusion (IR)-associated injuries are seemingly inevitable during liver transplantation and hepatectomy. Because Syrian hamsters demonstrate intrinsic tolerance to transplantation-like stimuli, cross-species comparative metabolomic analyses were conducted with hamster, rat, and donor liver samples to seek hepatic cold and IR-adaptive mechanisms. Lower hepatic phosphocholine contents were found in recipients with early graft-dysfunction and with virus-caused cirrhosis or high model for end-stage liver disease scores (≥30). Choline/phosphocholine deficiency in cultured human THLE-2 hepatocytes and animal models weakened hepatocellular cold tolerance and recovery of glutathione and ATP production, which was rescued by phosphocholine supplements. Among the biological processes impacted by choline/phosphocholine deficiency, 3 lipid-related metabolic processes were downregulated, whereas phosphocholine elevated the expression of genes in methylation processes. Consistently, in THLE-2, phosphocholine enhanced the overall RNA m6A methylation, among which the transcript stability of fatty acid desaturase 6(FADS6) was improved. FADS6functioned as a key phosphocholine effector in the production of polyunsaturated fatty acids, which may facilitate the hepatocellular recovery of energy and redox homeostasis. Thus, our study reveals the choline-phosphocholine metabolism and its downstream FADS6functions in hepatic adaptation to cold and IR, which may inspire new strategies to monitor donor liver quality and improve recipient recovery from the liver transplantation process.

Producing H2O2through a selective, two-electron (2e) oxygen reduction reaction (ORR) is challenging, especially when it serves as an advanced oxidation process (AOP) for cost-effective water decontamination. Herein, we attain a 2e-selectivity H2O2production using a carbon nanotube electrified membrane with ibuprofen (IBU) molecules laden (IBU@CNT-EM) in an ultrafast, single-pass electrofiltration process. The IBU@CNT-EM can generate H2O2at a rate of 25.62 mol gCNT–1h–1L–1in the permeate with a residence time of 1.81 s. We demonstrated that an interwoven, hydrophilic–hydrophobic membrane nanostructure offers an excellent air-to-water transport platform for ORR acceleration. The electron transfer number of the ORR for IBU@CNT at neutral pH was confirmed as 2.71, elucidating a near-2e selectivity to H2O2. Density functional theory (DFT) studies validated an exceptional charge distribution of the IBU@CNT for the O2adsorption. The adsorption energies of the O2and *OOH intermediates are proportional to the H2O2selectivity (64.39%), higher than that of the CNT (37.81%). With the simple and durable production of H2O2by IBU@CNT-EM electrofiltration, the permeate can actuate Fenton oxidation to efficiently decompose emerging pollutants and inactivate bacteria. Our study introduces a new paradigm for developing high-performance H2O2-production membranes for water treatment by reusing environmental functional materials.

Electric field measurements are crucial to monitor the electromagnetic environment in substations, measuring voltage on transmission lines, and assessing the condition of electrical equipment. This study fabricated a resonant torsional micro-electromechanical systems (MEMS) electric field sensor based on flexible piezoelectric lead zirconate titanate (PZT) thin-film actuation, aimed at addressing limitations observed in the existing and developing electric field sensor devices. The novel sensor topology was designed on the principle of charge induction, featuring a piezoelectric drive structure comprising four symmetrically distributed L-shaped cantilever beams and two pairs of staggered-coupled comb-tooth electrodes. The working principle and sensitivity of the sensor were analyzed. Using finite element software, an integrated simulation model of the structure was established for detailed modal analysis. The key structural parameters were optimized through parameter scanning, yielding an optimal design scheme. Subsequently, the fabrication process of the sensitive device was outlined, culminating in the successful preparation of the MEMS electric field sensor. Experimental validation on a dedicated platform demonstrated that the sensor exhibited robust tracking and response capabilities across high- and low-frequency sinusoidal electric fields ranging from 5 Hz to 10 kHz, without notable distortion or delay. Furthermore, the sensor achieved dc field measurement by modulating dc into ac, exhibiting good linearity in industrial frequency ac fields from 0 to 100 kV/m with a sensitivity of up to 5.64 mV/(kV/m). The results of this study offer foundational support for deploying the sensor in diverse applications within power systems, highlighting its potential for enhancing electromagnetic sensing technologies in practical settings.

Within the framework of “clean, low-carbon, and smart integration,” a pivotal element of the global energy Internet digital transformation lies in sensing technology. This paper addresses the enhancement of optical electric field sensors by investigating a technique grounded in the electric-optical energy coupling principle. A physical model is devised for electric field sensors, employing micro-ring-assisted Mach-Zender interferometric (MZI) structures with a slot-track architecture. Subsequently, a simulation method is employed to delineate the influence of the device's major structural parameters on the sensor's performance. Chip-based optical electric field sensors, coated with electro-optic polymer films, are then fabricated. Finally, a test platform is established to conduct an analysis encompassing time-frequency domain characterization and sensitivity of the sensor. The experimental findings demonstrate that the electric field sensor exhibits commendable linear input/output characteristics within an AC electric field ranging from 5.7 kV/m to 148.2 kV/m at industrial frequencies. The sensor achieves a sensitivity of 0.945 mV/(kV/m). Across high, medium, and low-frequency sinusoidal electric fields spanning from 50 Hz to 13.56 MHz, the sensor response exhibits no noteworthy aberrations or delays. The sensor performs adeptly in tracking and responding to strong transient electric fields within the μs range. Additionally, a comparative analysis with control sensor test results affirms that the slot-track resonant micro-ring structure devised in this paper significantly enhances the sensor's sensitivity and linear dynamic range. The sensor also exhibits good temperature stability in the 0 °C to 75 °C range. The research outcomes presented herein offer technical support for the multifaceted application of this technology in electric field measurement.

Chitinases play an important role in the molting process of insects and are potential targets for the development of green insecticides. Based on the feature that the +1/+2 sites in OfChtI, OfChtII, and OfChi-h have tryptophan residues in mismatch-parallel position, a strategy to introduce indole scaffold into chitinase inhibitors was proposed, and multitarget chitinase inhibitors containing N-methylcarbamoylguanidinyl and indole scaffold were successfully synthesized. The inhibitory activity showed that compound 8uexhibited significant inhibitory activity against OfChtI, OfChtII, and OfChi-h, with IC50values of 0.7, 0.79, and 0.58 μM, and Kivalues of 0.05 ± 0.005, 0.065 ± 0.004, and 0.025 ± 0.006 μM, respectively. In vivoinsecticidal activity showed that compounds 8aand 8gexhibited excellent insecticidal activity against Plutella xylostellaand Mythimna separata, with LC50values of 0.79 and 9.17 mg/L against P. xylostella, respectively, and 3.58 and 83.09 mg/L against M. separata, respectively, making them the most potent chitinase inhibitors with in vivoinsecticidal activity discovered to date. The inhibition mechanism and binding free energy results suggested that N-methylcarbamoylguanidinyl binds to the −1 catalytic site, while additional interactions acquired by π–π stacking and hydrophobic interactions of the indole scaffold with tryptophan increase the binding affinity of the targets to chitinases. This work provides a new direction for the development of chitinase inhibitors with compounds 8aand 8gpotentially serving as promising candidates for pesticide development.

The technology of combining multiple emission centers to exploit white-light-emitting (WLE) materials by taking advantage of porous metal–organic frameworks (MOFs) is mature, but preparing undoped WLE MOFs remains a challenge. Herein, a pressure-treated strategy is reported to achieve efficient white photoluminescence (PL) in undoped [Zn(Tdc)(py)]nnanocrystals (NCs) at ambient conditions, where the Commission International del’Eclairage coordinates and color temperature reach (0.31, 0.37) and 6560 K, respectively. The initial [Zn(Tdc)(py)]nNCs exhibit weak-blue PL consisting of localized excited (LE) and planarized intramolecular charge transfer (PLICT) states. After pressure treatment, the emission contributions of LE and PLICT states are balanced by increasing the planarization of subunits, thereby producing white PL. Meanwhile, the reduction of nonradiative decay triggered by the planarized structure results in 5-fold PL enhancement. Phosphor-converted light-emitting diodes based on pressure-treated samples show favorable white-light characteristics. The finding provides a new platform for the development of undoped WLE MOFs.

The development of wind energy is indispensable in the pursuit of global carbon neutrality. This article's analysis of observational data across China reveals the annual average wind speed declined at a rate of -0.167 m · s-1decade-1between 1981 and 2014. This rate is 33 times faster than projections from the Coupled Model Intercomparison Project (CMIP) of the World Climate Research Programme. We propose a novel wind power scale estimation method based on annual average wind speed, suitable for assessing climate change impacts. Considering China's planned wind power generation in 2030, climate change may increase the required wind installed capacity by over 25% under the observed trend scenario. In contrast, historical average and CMIP scenarios could substantially overestimate wind potential while underestimating the necessary future wind power development scale. Climate change poses potential adverse impacts on China's carbon peak goals, necessitating targeted measures to mitigate these effects.

Chitin-degrading enzymes are critical components in regulating the molting process of the Asian corn borer and serve as potential targets for controlling this destructive pest of maize. Here, we used a scaffold-hopping strategy to design a series of efficient naphthylimide insecticides. Among them, compound 8cexhibited potent inhibition of chitinase from OfChi-h and OfChtI at low nanomolar concentrations (IC50= 1.51 and 9.21 nM, respectively). Molecular docking simulations suggested that 8cbinds to chitinase by mimicking the interaction of chitin oligosaccharide substrates with chitinase. At low ppm concentrations, compound 8cperformed comparably to commercial insecticides in controlling the highly destructive plant pest, the Asian corn borer. Tests on a wide range of nontarget organisms indicate that compound 8chas very low toxicity. In addition, the effect of inhibitor treatment on the expression of genes associated with the Asian corn borer chitin-degrading enzymes was further investigated by quantitative real-time polymerase chain reaction. In conclusion, our study highlights the potential of 8cas a novel chitinase-targeting insecticide for effective control of the Asian corn borer, providing a promising solution in the quest for sustainable pest management.

Following percutaneous coronary intervention with stent placement to treat acute coronary syndromes, international clinical guidelines generally recommend dual antiplatelet therapy with aspirin plus a P2Y12receptor inhibitor for 12 months to prevent myocardial infarction and stent thrombosis. However, data on single antiplatelet therapy with a potent P2Y12inhibitor earlier than 12 months after percutaneous coronary intervention for patients with an acute coronary syndrome are scarce. The aim of this trial was to assess whether the use of ticagrelor alone, compared with ticagrelor plus aspirin, could reduce the incidence of clinically relevant bleeding events without an accompanying increase in major adverse cardiovascular or cerebrovascular events (MACCE).

Intravascular ultrasound-guided percutaneous coronary intervention has been shown to result in superior clinical outcomes compared with angiography-guided percutaneous coronary intervention. However, insufficient data are available concerning the advantages of intravascular ultrasound guidance for patients with an acute coronary syndrome. This trial aimed to investigate whether the use of intravascular ultrasound guidance, as compared with angiography guidance, improves the outcomes of percutaneous coronary intervention with contemporary drug-eluting stents in patients presenting with an acute coronary syndrome.

Insect growth regulators (IGRs) are important green insecticides that disrupt normal growth and development in insects to reduce the harm caused by pests to crops. The ecdysone receptor (EcR) and three chitinases OfChtI, OfChtII, and OfChi-h are closely associated with the molting stage of insects. Thus, they are considered promising targets for the development of novel insecticides such as IGRs. Our previous work identified a dual-target compound 6j, which could act simultaneously on both EcR and OfChtI. In the present study, 6jwas first found to have inhibitory activities against OfChtII and OfChi-h, too. Subsequently, taking 6jas a lead compound, 19 novel acetamido derivatives were rationally designed and synthesized by introducing an acetamido moiety into the amide bridge based on the flexibility of the binding cavities of 6jwith EcR and three chitinases. Then, their insecticidal activities against Plutella xylostella(P. xylostella), Ostrinia furnacalis(O. furnacalis), and Spodoptera frugiperda(S. frugiperda) were carried out. The bioassay results revealed that most of these acetamido derivatives possessed moderate to good larvicidal activities against three lepidopteran pests. Especially, compound I-17displayed excellent insecticidal activities against P. xylostella(LC50, 93.32 mg/L), O. furnacalis(LC50, 114.79 mg/L), and S. frugiperda(86.1% mortality at 500 mg/L), significantly better than that of 6j. In addition, further protein validation and molecular docking demonstrated that I-17could act simultaneously on EcR (17.7% binding activity at 8 mg/L), OfChtI (69.2% inhibitory rate at 50 µM), OfChtII (71.5% inhibitory rate at 50 µM), and OfChi-h (73.9% inhibitory rate at 50 µM), indicating that I-17is a potential lead candidate for novel multitarget IGRs. This work provides a promising starting point for the development of novel types of IGRs as pest management agents.

SiCf/Ti2AlNb-reinforced Ti17 (SiCf/Ti2AlNb/Ti17) composites were fabricated through hot isostatic pressing. The designed SiCf/Ti2AlNb/Ti17 composites exhibited excellent tensile properties, with tensile strengths of 1657 MPa at room temperature and 1830 MPa at 450 °C. The microstructure, fracture morphology, and longitudinal section of the composites were characterized by X-ray diffraction, scanning electron microscopy, and electron backscatter diffraction techniques. The fracture process of SiCf/Ti2AlNb/Ti17 composites during room-temperature tensile tests was as follows: the SiCf/Ti2AlNb reaction layer first fractured, the crack extended into the Ti2AlNb matrix, the Ti2AlNb matrix crack extended to the adjacent reaction layer and promoted fiber fracture, the crack extended to the Ti2AlNb/Ti17 interface, ultimately the Ti17 capsule fractured. The fracture process of SiCf/Ti2AlNb/Ti17 composites during 450 °C tensile tests was as follows: the SiCf/Ti2AlNb reaction layer first fractured, multiple fiber fractures occurred, and the crack in the reaction layer entered the Ti2AlNb matrix, the crack extended to the Ti2AlNb/Ti17 interface, eventually the Ti17 capsule fractured. The room-temperature tensile fracture was fitted to the LLS model, while the tensile fracture at 450 °C was fitted to the GLS model. The different fracture processes indicated that the SiCf/Ti2AlNb/Ti17 composites were suitable for exploiting fiber strength at 450 °C and therefore exhibited excellent tensile strength.

Microstructure evolution during the hot isostatic pressing (HIP) of continuous silicon carbide fiber-reinforced Ti (SiCf/Ti) composites has not been investigated. In this study, SiCf/Ti60 composites were prepared via the HIP solidification method of Ti60 precursor wires. The evolution of the microstructure of the Ti60 precursor wires and SiCf/Ti60 composites was characterized using electron backscatter diffraction microscopy and transmission electron microscopy techniques. The results showed that the deformation of α-Ti was mainly accomplished by basal dislocations and prismatic dislocations slip during the HIP process. After the completion of HIP, the low-angle grain boundaries (LAGBs) were reduced to 24.6%, and the average grain size of α-Ti was increased to 7.47 μm2. Two fiber textures, <0001>//axial direction (AD) and <10-10>//AD strength, were present in α-Ti, with a 38% increase in <10-10>//AD strength. The phase contents of 1.0% β-Ti and 0.6% (Ti, Zr)6Si3precipitated from different locations in the Ti60 matrix and induced changes in misorientation.

ELVDD provides the anode voltage of OLED. In the OLED pixel circuit, the source electrode of driving TFT is connected to ELVDD, and the drain electrode is connected to the anode of OLED. Most OLED panels of existing mobile phones set the ELVDD voltage to 4.6V.However, some OLED panels of new mobile phones set the ELVDD to 2.8V for energy‐saving purposes. As an important measure to reduce the logic power consumption of OLED display panel, ELVDD 2.8V setting is more and more common in mobile OLED panel design. Based on an OLED mobile phone panel, the comparison test of ELVDD setting 4.6V and 2.8V is carried out.

To investigate the effect of acupuncture onset time and synaptic structure in two different models of depression.

Ferroptosis, as a new form of regulated cell death, is implicated in various physiological and pathological processes. Developing a single probe for an independent analysis of multiple analytes related to ferroptosis can provide more accurate information and simplify the detection procedures, but it faces great challenges. In this work, we develop a fluorescent probe for the simultaneous detection of GSH through ratiometric fluorescence response and microviscosity via a fluorescence lifetime model. Based on the reversible Michael addition reaction between GSH and unsaturated C═C bond, the probe responds reversibly to GSH with a ratiometric fluorescence variation and a fast response time (t1/2= 4.7 s). At the same time, the probe is sensitive to environmental viscosity by changing its fluorescence lifetimes. The probe was applied to monitor the drug-induced ferroptosis process through both the classical Xc–/GSH/GPX4- and DHODH-mediated defense mechanisms. We hope that the probe will provide a useful molecular tool for the real-time live-cell imaging of GSH dynamics, which is benefit to unveiling related physiological and pathological processes.

OfChtI and OfChi-h are considered potential targets for the control of Asian corn borer (Ostrinia furnacalis). In this work, the previously reported OfChtI inhibitor 5fwas found to show certain inhibitory activity against OfChi-h (Ki= 5.81 μM). Two series of novel butenolide derivatives based on lead compound 5fwere designed with the conjugate skeleton, contributing to the π-binding interaction to chitinase, and then synthesized. Compounds 4a–land 7a–pdisplayed excellent inhibitory activities against OfChtI and OfChi-h, respectively, at a concentration of 10 μM. Compound 4hwas found to be a good dual-Chitinase inhibitor, with Kivalues of 1.82 and 2.00 μM against OfChtI and OfChi-h, respectively. The inhibitory mechanism studies by molecular docking suggested that π–π stacking interactions were crucial to the inhibitory activity of novel butenolide derivatives against two different chitinases. A preliminary bioassay indicated that 4hexhibited certain growth inhibition effects against O. furnacalis. Butenolide-like analogues should be further studied as promising novel dual-chitinase inhibitor candidates for the control of O. furnacalis.

Locust mandibles have stiff cuticles to process rough food. Therefore, the mandible is a reservoir of stiff structural proteins (SPs). Here, LmCPH-1, the most abundant SP in locust mandibles, is reported to be an indispensable stiff SP in mandibles. In vivo, suppression of LmCPH-1 expression seriously weakens the mechanical properties of the mandible. In vitro, LmCPH-1 undergoes hierarchical self-assembly to form a film with an ultrahigh modulus (12 GPa), which outperforms most protein-based materials. The stiffness of LmCPH-1 film can be attributed to its high β-sheet/β-crystal content formed through self-assembly. Molecular dynamics simulations indicate that the C-terminal region of LmCPH-1 plays a vital role in its self-assembly process. We conclude that LmCPH-1 strengthens the locust mandible by forming a stiff cement to fill the chitin scaffold. The findings not only represent a universal reinforcing mechanism of insect cuticle but also provide a potent starting material for sustainable materials.

The metallurgical quality control of magnesium (Mg) and Mg alloys in melting process is required to ensure a satisfied mechanical and corrosion performance, while the typical used steel crucible introduces impurities and interfacial interaction during melting process. Therefore, a systematic study about impurities diffusion and interfacial interaction between molten Mg and steel is necessary. In the present study, the interfacial reaction between molten AZ91D Mg alloy and mild steel during melting process was investigated with the melting temperatures of 700 °C, 750 °C and 800 °C. The results show that Al(Fe, Mn) intermetallic layer is the intermetallic primarily formed at the interfaces of AZ91D melt and mild steel. Meanwhile, Al8(Mn, Fe)5is indexed between Al(Fe, Mn) and AZ91D. AlFe3C appears between the mild steel and Al(Fe, Mn) at 700 °C and 750 °C, but absent at 800 °C due to the increased solubility of carbon in Mg matrix. It is found that the growth of the intermetallic layer is controlled by diffusion mechanism, and Al and Mn are the dominant diffusing species in the whole interfacial reaction process. By measuring the thickness of different layers, the growth constant was calculated. It increases from 1.89(±0.03)×10−12m2·s−1at 700 °C to 3.05(±0.05)×10−12m2·s−1at 750 °C, and 5.18(±0.05)×10−12m2·s−1at 800 °C. Meanwhile, the content of Fe is linearly increased in AZ91D with the increase of holding time at 700 °C and 750 °C, while it shows a significantly increment after holding for 8 h at 800 °C, indicating holding temperature is more crucial to determine the Fe content of AZ91D than holding time.

The objective of this study was to examine the relationship between the variables of the value-belief-norm (VBN) theory and the adoption of green consumption behaviors among Chinese youth. The online survey questionnaire was distributed to a convenience sample of young Chinese consumers aged 18–35 years through the platforms WJX and WeChat. The data collection period spanned from September to December 2022. The analysis involved a total of 1074 participants, and the statistical technique employed was partial least squares structural equation modeling (PLS-SEM) using Smart-PLS 4.0. Common-method bias, multivariate normality, validity, and reliability were also assessed. The results revealed that biospheric values (BV), altruistic values (AV), the new ecological paradigm (EP), awareness of consequences (AC), the ascription of responsibility (AR), and personal norms (PN) significantly and positively influenced intention toward green consumption practices (IGP), which, in turn, had a significant positive influence on the adoption of green consumption practices (AGP). Additionally, GT did not moderate the association between IGP and AGP. This study contributes to the literature on green consumption by analyzing VBN theory’s influence on Chinese youth’s behavior toward green consumption practices to understand and promote green behavior. This study’s findings suggest that promoting ecological awareness and responsibility, developing green values and trust, and strengthening personal norms can encourage green consumption practices among Chinese youth. Policymakers, businesses, and marketers can benefit from these findings to promote green consumption and sustainability in China.

Let BHbe a fractional Brownian motion with Hurst index 12≤H<1. In this paper, we consider the equation (called the Ornstein-Uhlenbeck process with a linear self-repelling drift) dXtH=dBtH+σXtHdt+νdt−θ(∫0t(XtH−XsH)ds)dt,where θ < 0, σ, v∈ ℝ. The process is an analogue of self-attracting diffusion (Cranston, Le Jan. Math Ann, 1995, 303: 87–93). Our main aim is to study the large time behaviors of the process. We show that the solution XHdiverges to infinity as t tends to infinity, and obtain the speed at which the process XHdiverges to infinity as ttends to infinity.

ABSTRACT This study presents the results of the utilization of a cement-based composite stabilizer on soil modification. The effects of additives, including NaOH, Ca[Cl.sub.2], [Na.sub.2]Si[O.sub.3], NaOH/Ca[Cl.sub.2] and Triethanolamine, on the [...]

Separating ethane (C2H6) from ethylene (C2H4) is an essential and energy-intensive process in the chemical industry. Here, we report two flexible diamondoid coordination networks, X-dia-1-Niand X-dia-1-Ni0.89Co0.11, that exhibit gate-opening between narrow-pore (NP) and large-pore (LP) phases for C2H6, but not for C2H4. X-dia-1-Ni0.89Co0.11thereby exhibited a type F–IV isotherm at 273 K with no C2H6uptake and a high uptake (111 cm3g–1, 1 atm) for the NP and LP phases, respectively. Conversely, the LP phase exhibited a low uptake of C2H4(12.2 cm3g–1). This C2H6/C2H4uptake ratio of 9.1 for X-dia-1-Ni0.89Co0.11far surpassed those of previously reported physisorbents, many of which are C2H4-selective. In situvariable-pressure X-ray diffraction and modeling studies provided insight into the abrupt C2H6-induced structural NP to LP transformation. The promise of pure gas isotherms and, more generally, flexible coordination networks for gas separations was validated by dynamic breakthrough studies, which afforded high-purity (99.9%) C2H4in one step.

The operation efficiency of the manipulator is placed in the primary position in automatic production. This paper proposes a coordinated control strategy for joint servo and visual servo to enable timely transfer and accurate gripping in the working area. Aiming at the issues of chattering and slow convergence of traditional sliding mode controller, a fast variable power reaching rate on the basis of the non-singular fast terminal sliding mode controller is proposed, which can effectively reduce the convergence time and chattering. For the purpose of addressing the problem that the traditional visual servo control method is sensitive to the environment, a visual servo controller based on integral sliding mode is proposed, to ensure the favorable positioning accuracy of the manipulator. Based on the two proposed controllers mentioned above, a coordinated control strategy is used to implement the control of the manipulator. Finally, the upper computer software is developed using the C# programming language to monitor the workstation. The feasibility of the above-mentioned method is verified through multiple simulations and experiments.

An effective Ag(I)-mediated annulation of 2-(2-enynyl)pyridines and propargyl amines was developed, unexpectedly affording a broad range of functionalized 1-(2H-pyrrol-3-yl)indolizines in moderate to excellent yields. The developed method is characterized by operational simplicity, ready availability of starting materials, high regioselectivity, and broad substrate scope under mild reaction conditions. The Ag(I)-promoted cyclization of 2-(2-enynyl)pyridines and propargyl amines possibly results in the formation of the spiroindolizine, the ring-opening rearrangement of which may give the 1-(2H-pyrrol-3-yl)indolizine. Furthermore, a gram-scale reaction and synthetic transformations are also studied.

Localization and tracking are important components for ground-moving target indication (GMTI). The traditional range-Doppler (RD) localization model is always applied to locate stationary targets in bistatic synthetic aperture radar (BiSAR). However, for moving targets, this localization model is no longer applicable due to the strong coupling of position and velocity with Doppler frequency. To address the severe challenge, this article proposes a joint moving target localization and tracking method for BiSAR-GMTI via transmitter–receiver trajectories extraction and inversion. The key innovation is the derivation of closed-form localization results for moving targets, which is beneficial for the quantitative analysis of localization error. The proposed method is structured into three main parts. First, to accurately capture the range history trajectory information, a segmented fitting extraction and inversion framework is designed. Second, to estimate the moving target’s initial state and demonstrate localization observability, joint range localization equations are established where the closed-form localization result of the moving target is derived. Finally, by defining the appropriate state transition equation and observation equation, and incorporating particle filtering (PF), the position measurement errors of bistatic platforms are weakened, and accurate tracking of moving targets is realized. The proposed method only utilizes range information, mitigating localization errors caused by Doppler estimation inaccuracies effectively. Simulation experiments and real data both demonstrate the localization and tracking accuracy of moving targets.

Cyclic GMP-AMP synthase (cGAS) is a major cytosolic DNA sensor that plays a significant role in innate immunity. Upon binding to double stranded DNA (dsDNA), cGAS utilizes GTP and ATP to synthesize the second messenger cyclic GMP-AMP (cGAMP). The cGAMP then binds to the adapter protein stimulator of interferon genes (STING) in the endoplasmic reticulum, resulting in the activation of the transcription factor interferon regulatory factor 3 (IRF3) and subsequent induction of type I interferon. An important question is how cGAS distinguishes between self and non-self DNA. While cGAS binds to the phosphate backbone of DNA without discrimination, its activation is influenced by physical features such as DNA length, inter-DNA distance, and mechanical flexibility. This suggests that the recognition of DNA by cGAS may depend on these physical features. In this article we summarize the recent progress in research on cGAS-STING pathway involved in antiviral defense, cellular senescence and anti-tumor response, and focus on DNA recognition mechanisms based on the physical features.

With the rapid popularization and development of the global positioning systems, location-based services (LBSs) are springing up to provide mobile internet users with door-to-door services. The users’ privacy becomes one of the main concerns of such services, as location data reflects various sensitive information, such as home address, employment and even health conditions. Releasing the aggregated mobility datasets, i.e., the population of mobile users at different regions in the area, is one of the solutions in solving the privacy concerns that covers the individual users’ information and accepted as a valid privacy preserving method in releasing mobility datasets. However, in a recent research, by exploiting the uniqueness and regularity of mobility data, individual trajectories can be recovered from the aggregated mobility datasets with accuracy about 73–91%. In this paper, we propose a novel differential privacy based probabilistic mechanism for mobility datasets releasing (DP-Mobi), in which the privacy preserved population distributions are generated and released to support LBSs. We employ a probabilistic structure count min sketch in the mechanism to count the number of users at different regions, and add noise drawn from Laplace distribution to perturb the sketches. Meanwhile, we prove the perturbed sketches satisfy differential privacy, so that the users are able to control the privacy level by tuning the parameters of Laplace distribution. Through evaluation, we show that comparing with another privacy preserving approach in resisting the attack model, our mechanism DP-Mobi achieves 8% more recovery error with the same utility loss.

For many years, project management maturity models (PMMM) derived from the software industry have brought immeasurable benefits. However, the adoption and investigation of PMMM in the construction field have been weak and insufficient, particularly in construction consulting services (CCS). Moreover, professionals have gradually realized the importance of non-process factors (e.g., teamwork, culture, leadership) in the evaluation of PMMM. This study describes the construction of PMMM for CCS that considers non-process factors and combines them with CCS-specific process factors. To verify the effectiveness of the proposed model, we conduct a case study on the overall project management consultancy for China's 2010 Winter Expo. The results would fill in the PMMM research gap in CCS and provide practitioners with ideas to improve their performance.

Group testing involves discovering a small subset of distinguished subjects from a large population while efficiently reducing the total number of tests. It has been widely used for industrial testing, information technology, and biology, especially epidemic screening. Tests, in reality, are noisyfor the presence of false outcomes. Some tests are accurate but time-consuming, while others are cheaper but less accurate. Exactly which test to use is constrained by various considerations, such as availability, cost, accuracy, and efficiency. In this paper, we propose flexible, efficient, and accurate tests(FEATs). FEATs are based on group testing with simple but careful designs by incorporating ideas such as close contact cliques and repeated tests. FEATs could dramatically improve the efficiency or accuracy of existing tests. For example, for accurate but slow tests, the FEAT can improve efficiency multiple times without compromising accuracy. On the other hand, for fast but inaccurate tests, the FEAT can sharply reduce the false-negative rate (FNR) and significantly increase efficiency. Theoretical justifications are provided. We point out some scenarios where the FEAT can be effectively employed.

Supramolecular systems feature dynamic, reversible and stimuli-responsive characteristics, which are not easily achieved by molecular entities. The last decade has witnessed tremendous advances in the investigations of supramolecular systems for various bioapplications, which include drug delivery, anticancer therapy, antibacterial therapy, photodynamic therapy, photothermal therapy, combination therapy, antidotes for residual drugs or toxins, and bioimaging and biosensing. Host-guest chemistry has played a key role in the development of such bioactive supramolecular systems, and natural macrocycles (such as cyclodextrins), synthetic macrocycles (such as calixarenes, cucurbit[n]urils, and pillararenes), and porous framework polymers (such as supramolecular organic frameworks and flexible organic frameworks) have been most successfully used as hosts to build different kinds of host-guest systems for attaining designed biofunctions. The self-assembly of rationally designed amphiphilic molecules, macromolecules and polymers represent another important approach for the construction of supramolecular architectures with advanced biofunctions. In this review, we summarize the important contributions made by Chinese researchers in this field, with emphasis on those reported in the past five years.

Sea clutter suppression plays a crucial role in maritime moving target indication. However, in the bistatic synthetic aperture radar (BiSAR) system, traditional space-time adaptive processing (STAP) method cannot satisfy the expected performance due to severe range cell migration (RCM), Doppler frequency migration (DFM), nonstationary clutter, and spatio-temporal spectrum expansion caused by the internal motion of sea clutter. STAP based on sparse recovery (SR-STAP) is an effective method for clutter suppression, but two major problems still remain: 1) the multiple samples for solution need to satisfy the same spatio-temporal distribution characteristics and, nevertheless, such consistency is not applicable when considering violent internal motion of sea clutter and 2) the computational complexity is exceedingly high. To issue these problems, an efficient matrix sparse recovery STAP (MSR-STAP) method based on Kronecker transform is proposed. The proposed method mainly consists of three steps: 1) generalized keystone transform in preprocessing stage is used for RCM correction and DFM compensation; 2) multiple spatio-temporal samples acquisition strategy for cell under test (CUT) is designed, to enhance the solution robustness; and 3) an efficient MSR-STAP model is established and solved. Subsequently, the space-time filter is designed without clutter covariance matrix estimation, to facilitate effective sea clutter suppression. Compared with existing SR-STAP methods, computational complexity of the proposed method decreases by orders of magnitude, and the spatio-temporal spectrum expansion effect is greatly reduced. The sea clutter suppression performance is verified with numerical simulations.

Friction properties of rock are closely connected with the anisotropy. The anisotropy of rock friction can provide a valuable assessment for geotechnical and geological engineering. In this study, the rotary friction tests were conducted to analyze the water effect on the friction property and the friction anisotropy of the four types of rock. The drilling response model (DD-model) was employed to characterize the rotary friction behavior of the rocks. The parameters of this model include the three types of friction parameters: 1/ς, μ, and f, where 1/ςand μare constant, and fis a variable. A quantitative method is proposed for assessing the anisotropy of rock friction. The results of the rotary friction tests indicate that the relation between torque force and thrust force conforms to the DD-model. The changes of two friction constants 1/ςand μfrom dry state to water-saturated state suggest that the water effect on the friction strength of the rocks exhibits significant anisotropy. The friction strength determined by the friction variable fincreases first, then decreases, and finally stabilizes with the increasing of depth. AIfis an anisotropy index calculated by the proposed method. The percentage difference of the average value of AIfbetween water-saturated and dry states shows the degree of the water effect on the friction anisotropy of the rocks, mudstone (MU) > granite (GR) > fine sandstone (FS) > argillaceous siltstone (AS). The quantitative model is hopefully constructed for characterizing the relation between the anisotropic friction strength of rock and the moisture state in future.

Quantum sensors based on solid-state defects, such as the nitrogen-vacancy (NV) center in diamond, offer very good room-temperature sensitivity, long-term stability, and the potential for calibration-free measurements. However, most quantum sensors still suffer from a bulky size and weight, low energy efficiency, and high costs, prohibiting their widespread use. Here, we present custom-designed chip-integrated microwave (MW) electronics for a miniaturized, low-cost, and highly scalable quantum magnetometer based on NV centers in diamond. The presented electronics include a quadrature phase-locked loop (QPLL) chip to generate the required local oscillator signal at around 7 GHz with a wide tuning range of 22% and a low phase noise (PN) of −122 dBc/Hz at 1-MHz offset from a 7-GHz carrier for broadband low-noise magnetometry. In addition, the magnetometer electronics comprise a 4-channel transmitter chip, which can provide currents up to 412 mApp into a custom-designed inductor over a wide frequency range from 6.4 to 8 GHz. In combination with a custom-designed coil, manufactured on a glass substrate for optical transparency, which features a large active area of ( $\pi { \times } 180 { \times }180~\mu \text {m}^{2}$ ), this current is sufficient to produce strong MW magnetic fields up to $B_{{1}} = (1/2) \cdot B_{\text {ac}} = 170~{\mu \mathrm {T}}$ , enabling pulsed optically detected magnetic resonance (ODMR) experiments. In proof-of-concept ODMR experiments, the presented chip-based spin control system produces fast Rabi oscillations of 5.49 MHz. The measured dc and ac magnetic field limits of detection (LOD) of the presented magnetometer are 32 nT/Hz $^{\text {1/2}}$ and 300 pT/Hz $^{\text {1/2}}$ , respectively.

New energy vehicle has gradually become a new trend in global transportation development due to the renewable and environmentally friendly fuel they consume. At the same time, the charging safety issue of lithium-ion batteries for the electric vehicle limits the development of the industry. From the perspective of the electric vehicle charging data and based on the timing characteristics that lithium-ion battery charging has, this paper proposes a hybrid neural network electric vehicle thermal runaway temperature warning model, which combines an attention mechanism (AT), a temporal convolutional network (TCN), and a long- and short-term memory network (LSTM). Firstly, the charging temperature of the electric vehicle is predicted by establishing hybrid neural networks model, then comparing the real-time charging data with the predicted data, calculating the residual difference between the two. Analyzing the residual difference by using the sliding window method and then calculating the pre-warning threshold. Finally, realizing the thermal out-of-control early warning based on the residual difference to complete the monitoring of the charging status of the electric vehicle. The experimental results show that the AT-TCN-LSTM charging early warning model has higher accuracy and faster speed than other models, so that the method can accurately and quickly respond to charging accidents and achieve the early warning effect. At the same time, in order to verify the generalization ability of the model, transfer learning is used to transfer the trained AT-TCN-LSTM model to the charging data of different charging times and different vehicle types, and the results show that the model after transfer learning still has more accurate prediction accuracy.

Objective: To investigate the serum lipid profiles of patients with localized osteosarcoma around the knee joint before and after neoadjuvant chemotherapy. Methods: After retrospectively screening the data of 742 patients between January 2007 and July 2020, 50 patients aged 13 to 39 years with Enneking stage II disease were included in the study. Serum lipid levels, including total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), lipoprotein-α [Lp(a)], and apolipoprotein A1, B, and E (ApoA1, ApoB, and ApoE), and clinicopathological characteristics were collected before and after neoadjuvant chemotherapy. Results: The mean levels of TC, TG, and ApoB were significantly increased following neoadjuvant chemotherapy (16%, 38%, and 20%, respectively, vs.pretreatment values; P&lt;0.01). The mean levels of LDL-C and ApoE were also 19% and 16% higher, respectively (P&lt;0.05). No correlation was found between the pretreatment lipid profile and the histologic response to chemotherapy. An increase in Lp(a) was strongly correlated with the Ki-67 index (R=0.31, P=0.023). Moreover, a trend toward longer disease-free survival (DFS) was observed in patients with decreased TG and increased LDL-C following chemotherapy, although this difference was not statistically significant (P=0.23 and P=0.24, respectively). Conclusion: Significant elevations in serum lipids were observed after neoadjuvant chemotherapy in patients with localized osteosarcoma. There was no prognostic significance of pretreatment serum lipid levels on histologic response to neoadjuvant chemotherapy. The scale of increase in serum Lp(a) might have a potential prognostic role in osteosarcoma. Patients with increased LDL-C or reduced TG after chemotherapy seem to exhibit a trend toward favorable DFS.

Recombinant human type 5 adenovirus (H101) is an oncolytic virus used to treat nasopharyngeal carcinoma. Owing to the deletion of the E1B-55kD and E3 regions, H101 is believed to selectively inhibit nasopharyngeal carcinoma. Whether H101 inhibits other type of tumors via different mechanisms remains unclear. In this study we investigated the effects of H101 on melanomas. We established B16F10 melanoma xenograft mouse model, and treated the mice with H101 (1 × 108TCID50) via intratumoral injection for five consecutive days. We found that H101 treatment significantly inhibited B16F10 melanoma growth in the mice. H101 treatment significantly increased the infiltration of CD8+T cells and reduced the proportion of M2-type macrophages. We demonstrated that H101 exhibited low cytotoxicity against B16F10 cells, but the endothelial cells were more sensitive to H101 treatment. H101 induced endothelial cell pyroptosis in a caspase-1/GSDMD-dependent manner. Furthermore, we showed that the combination of H101 with the immune checkpoint inhibitor PD-L1 antibody (10 mg/kg, i.p., every three days for three times) exerted synergic suppression on B16F10 tumor growth in the mice. This study demonstrates that, in addition to oncolysis, H101 inhibits melanoma growth by promoting anti-tumor immunity and inducing pyroptosis of vascular endothelial cells.

The incidence of atrioventricular conduction system damage during the catheter ablation procedure has long been a safety concern in patients with atrioventricular nodal re-entrant tachycardia (AVNRT). Pulsed-field ablation (PFA) with high tissue selectivity is a promising technique to address this problem in patients with AVNRT.

Biological systems can create materials with intricate structures and specialized functions. In comparison, precise control of structures in human-made materials has been challenging. Here we report on insect cuticle peptides that spontaneously form nanocapsules through a single-step solvent exchange process, where the concentration gradient resulting from the mixing of water and acetone drives the localization and self-assembly of the peptides into hollow nanocapsules. The underlying driving force is found to be the intrinsic affinity of the peptides for a particular solvent concentration, while the diffusion of water and acetone creates a gradient interface that triggers peptide localization and self-assembly. This gradient-mediated self-assembly offers a transformative pathway towards simple generation of drug delivery systems based on peptide nanocapsules.

In this article, we firstly propose a low acoustic frequency sensing system based on small-angle tilted fiber Bragg grating (TFBG), which is used in the sensor head to achieve a high sensitivity. The sensitivity of the proposed diaphragm based acoustic sensing system is theoretically and experimentally proved closely related to the coupling methods and efficiency of ghost mode. In the experiment, the sensing TFBG is tightly bounded on the designed low-frequency polyethylene terephthalate (PET) transducer membrane with a fixed boundary and its ghost mode will have a large wavelength drift and change of amplitude in response to the periodic elastic deformation of the transducer membrane under acoustic pressure. With using the edge filtering demodulation method, the low-frequency acoustic can be effectively and sensitively measured. The theoretical analysis and experimental results indicate that the wavelength and intensity respond linearly to the acoustic pressure. The proposed system can achieve a maximal sensitivity of about 509 mV/Pa in the frequency range of 40 Hz $\sim$85 Hz, a minimum detectable pressure (MDP) of 93$\mu$ Pa/Hz$^{1/2}$@55 Hz and signal-to-noise ratio (SNR) of 59 dB. The sensor also demonstrates a flat frequency response within 85 Hz$\sim$1500 Hz. The sensor operates stably with a peak fluctuation of about $\pm$ 1 mV over 1 h, and about 1.8% for the percentage standard deviation. The proposed acoustic sensor has advantages of high sensitivity at low frequency, high stability and high SNR, simple fabrication, and excellent repeatability.

Power grids play a crucial role in connecting electricity suppliers and consumers. They facilitate efficient power transmission and energy management, significantly contributing to the transition toward low-carbon practices across both upstream and downstream sectors. Effectively managing carbon reduction in the power industry is essential for enhancing carbon reduction efficiency and achieving dual-carbon goals. Recent studies have focused on the outcomes of carbon reduction efforts rather than the management process. However, when power grids prioritize the process of carbon reduction in their management, they are more likely to achieve better results. To address this gap, we propose an evaluation model for managing carbon reduction activities in power grids, comprising the carbon management efficiency (CME) module based on the maturity model and the carbon reduction efficiency (CRE) module based on the entropy method. The CME module provides a scorecard corresponding to a detailed and continuous evaluation model for carbon management processes to calculate its performance. Simultaneously, the CRE module relates carbon reduction results to the development direction of the government and power grid, allowing for effective adjustments and updates based on actual situations. The evaluation model was applied to provincial power grids within the China Central Power Grid. The results reveal that despite some fluctuations in carbon reduction performance, provincial power grids within the China Central Power Grid have made continuous progress in carbon reduction efforts. According to the synergy model, there is evidence suggesting that power grids are steadily improving their carbon reduction performance, and a more organized approach would lead to a greater degree of synergy. The evaluation model applies to power grids, and its framework can be extended to other industries, providing a theoretical reference for evaluating their carbon reduction efforts.

The spray pyrolysis technology produces Bi-2223 precursor powders in large quantities with high stability. In our study, we have combined this method with the two-powder process to enhance the current-carrying performance of Bi-2223 tapes. Aiming at understanding the effect of Ca-Cu-O particle size on the phase evolution mechanism of Bi-2223 high-temperature superconducting tapes. Our findings indicate that with the bigger Ca-Cu-O particle, the Bi-2223 formation temperature increases, but the formation rate decreases. The Bi-2223 tape fabricated with the precursor powders containing larger Ca-Cu-O particles, with an average size of ∼2.00 ± 0.05 um, exhibits better current-carrying performance. It shows an increase of ∼30% compared to the critical current Ic of that with smaller particles. This enhancement is attributed to the slower reaction of the Ca-Cu-O particles with larger size, leading to complete formation and no decomposition even when subjected to 830 °C for 50 hours.

Our aim was to determine the relative effectiveness of two dietary macronutrient patterns (LFHC (low-fat, high-carbohydrate) diets and LCHF (low-carbohydrate, high-fat) diets) on weight loss and cardiovascular risk factors. We searched four databases including MEDLINE, EMBASE, Cochrane Library, and Web of Science to identify the eligible studies on March 13, 2020. Randomized clinical trials (RCT) were included which compared the effect of two diets (LFHC and LCHF) on weight loss, blood pressure, serum liquids, and blood glucose in overweight or obesity adults. Standardized mean difference (SMD) and 95% confidence interval (CI) were used for the pooled results. This paper included eleven studies involving 739 participants. Compared with LFHC diets, LCHF diets had a greater effect on weight loss (SMD = –1.01 kg; 95% CI –1.99 to –0.04, p= 0.04) and HDL-cholesterol changes (SMD = 0.82 mmol/l; 95% CI 0.43 to 1.21, p< 0.0001), but a smaller effect on total cholesterol decrease (SMD = 0.63 mmol/l; 95% CI 0.18–1.08, p= 0.006) and LDL-cholesterol decrease (SMD = 0.59 mmol/l; 95% CI 0.11–1.18, p= 0.05). Between the two groups, changes in lean mass, fat mass, systolic blood pressure, diastolic blood pressure, triglycerides, and glucose were non-significant. To conclude, both diets are effective for weight control and reduction of cardiovascular risk factors. And further studies with long-term follow-up are needed to confirm our results.

High-impedance arc faults (HIAFs) occur frequently in distribution networks. An electric arc can easily cause serious accidents. The detection and prevention of arc faults are crucial for the safety of electrical systems and equipment. The electrical characteristics of an electric arc are influenced by various factors such as the environmental pressure, current magnitude, and arc length. Describing these characteristics using conventional mathematical models can be challenging. Hence, in this work, a novel mathematical–physical arc model was established based on the arc discharge mechanism. Compared with the conventional mathematical model, the proposed arc model is more accurate and can reflect the variations in the attribute parameters during the arc discharge process. The proposed model has excellent universality and is applicable under various discharge conditions including varying air pressure, ground resistance, and arc gap length. The model can be used in the detection of HIAFs under different discharge conditions.

IntroductionAlthough lung function measures are associated with cardiovascular disease (CVD), the added predictive values of these measures remain unclear.MethodsFrom the UK Biobank, 308 415 participants free of CVD with spirometry parameters were included. The CVD outcomes included were defined by QRISK3, the American College of Cardiology/American Heart Association (ACC/AHA) and the European Systematic Coronary Risk Evaluation (SCORE) prediction models, respectively. Cox proportional hazard models were used to estimate the associations of lung function measures with CVD outcomes. The predictive capability was determined by the decision curve analyses.ResultsOver a median follow-up of 12.5 years, 21 885 QRISK3 events, 12 843 ACC/AHA events and 2987 SCORE events were recorded. The associations of spirometry parameters with CVD outcomes were L-shaped. Restrictive and obstructive impairments were associated with adjusted HRs of 1.84 (95% CI: 1.65 to 2.06) and 1.72 (95% CI: 1.55 to 1.90) for SCORE CVD, respectively, compared with normal spirometry. Similar associations were seen for QRISK3 CVD (restrictive vs normal, adjusted HR: 1.30, 95% CI: 1.25 to 1.36; obstructive vs normal, adjusted HR: 1.20, 95% CI: 1.15 to 1.25) and ACC/AHA CVD (restrictive vs normal, adjusted HR: 1.39, 95% CI: 1.31 to 1.47; obstructive vs normal, adjusted HR: 1.26, 95% CI: 1.19 to 1.33). Using models that integrated non-linear forced expiratory volume in 1 s led to additional 10-year net benefits per 100 000 persons of 25, 43 and 5 for QRISK3 CVD at the threshold of 10%, ACC/AHA CVD at 7.5% and SCORE CVD at 5.0%, respectively.ConclusionClinicians could consider spirometry indicators in CVD risk assessment. Cost-effectiveness studies and clinical trials are needed to put new CVD risk assessment into practice.

The development and research of high strength and conductivity materials are essential for the advancement of high-field magnets, including pulsed magnets. This study investigates the effect of electromagnetic fields on the solidification casting of binary Cu-6wt%Ag alloy ingots with diameters of 40 and 160 mm. A 3D numerical simulation is performed utilizing the continuum model with conservation of total momentum, mass, energy, and species. The results indicate that applying electromagnetic stirring (EMS) to small cross-section ingots can cause many randomly distributed small regions with higher segregation degrees inside the ingot, which is not conducive to improving the macrosegregation inside the ingot. For large cross-section ingots without EMS, compared to small cross-section ingots, there is more severe macrosegregation inside the ingot, especially the extreme center segregation with a maximum segregation degree of about 414%. EMS can effectively control macrosegregation within a specific range and eliminate center segregation. When the linear EMS's magnetic induction intensity is set to 0.06 T, the maximum segregation degree near the ingot center can be reduced to less than 260%. Simultaneously, the EMS induced forced convection is also instability, leading to numerous haphazard solute accumulations and depletions, which explains many small segregation regions in the ingot. In terms of improving macrosegregation in large cross-section ingots, Linear EMS has a definite advantage over rotary EMS. It is possible to keep the entire segregation degree in the ingot below 100% when the linear EMS's magnetic induction intensity is set to 0.036 T and the stirring frequency is 4 Hz. The ideal stirring parameters range for linear EMS is to maintain the magnetic induction intensity at around 0.036 T and the stirring frequency in the range of 4–8 Hz.

Directed energy deposition-arc (DED-Arc) technology has the advantages of simple equipment, low manufacturing cost and high deposition rate, while the use of DED-Arc has problems of microstructure inhomogeneity, position dependence of macroscopic mechanical properties and anisotropy. Therefore, it is necessary to carry out a subsequent heat treatment to improve its microstructure uniformity, mechanical properties and superelasticity. In this investigation, the DED-Arc 15-layer NiTi alloy thin-walled parts with the solution treatment at different process parameters were studied to analyze the effects of solution heat treatment on microstructure, phase composition, phase transformation, microhardness, tensile and superelasticity. The temperature range of solution treatment is 800–1050 °C, and the treatment time range is 1–5.5 h. The results show that after solution treatment at 800 °C/1 h, the content of precipitated phase decreases, the grain is refined, the microhardness increases, and the mechanical properties in the 0° direction are improved. The strain recovery rate after 10 tensile cycles has increased from 37.13% (as-built) to 49.25% (solid solution treatment). This research provides an effective post treatment method for high-performance DED-Arc NiTi shape memory alloys.