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The incidence of bone metastasis (BM) in colorectal cancer (CRC) patients is low and the prognosis is poor. There is no clear conclusion on the risk factors affecting the survival of CRC patients with BM. The aim of this study was to investigate the factors that may affect the prognosis of CRC patients with BM. The clinical and pathological data of CRC patients with BM were retrospectively analyzed. The overall survival after BM diagnosis was estimated using the Kaplan–Meier method and Log-rank test, and a multivariable cox regression model was used to identify the prognostic factors of overall survival. This study included 178 CRC patients with BM, of whom 151 had left-sided CRC and 27 had right-sided colon cancer. 1124 CRC patients with BM from the SEER database were included to perform a sensitivity analysis of the primary outcome. Multivariate analysis showed that the N staging, site of BM, and primary tumor sidedness (PTS) were independent prognostic factors for CRC with BM. Among them, right-sided colon cancer patients with BM had a poorer prognosis. Sensitivity analyses showed that PTS was an independent prognostic factor in CRC patients with BM. Primary tumor sidedness and N stage may be potential prognostic markers for BM of CRC. The prognosis of N0 stage CRC with BM is better, while the prognosis of right-sided colon cancer is poor.

In order to study the bond slip behavior of red mud concrete-filled square steel stubs, fifteen red mud concrete filled square steel tubes short column specimens were designed for the push-out test. Five parameters including replacement rate of red mud mass, concrete strength, embedment length, length diameter ratio, width to thickness ratio were regarded as variable parameters in the experiment. Through experiment, the load-slip curves of red mud concrete filled square steel tubes were obtained and analyzed.The results show that the load slip curves of red mud concrete filled square steel tubes can be classified into five stages: no slipping section, ascending section, descending section, re-ascending section and re-descending section.The bond strength increases first and then decreases with the increase of red mud substitution rate.When the substitution rate of red mud is 5%, the bond strength reaches the maximum. When the substitution rate of red mud is 20%, the bond strength is equivalent to that of normal concrete filled steel tube.