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A recent study conducted at the First Affiliated Hospital of Henan University of Chinese Medicine in China aimed to develop nomograms for predicting lung metastasis probability and cancer-specific survival (CSS) in patients with malignant primary osseous spinal neoplasms (MPOSN). The researchers collected data from 1,298 patients with spinal primary osteosarcoma, chondrosarcoma, Ewing sarcoma, and chordoma. The study identified various predictors for lung metastasis, including histologic type, grade, lymph node involvement, tumor size, tumor extension, and other site metastasis. The nomograms developed in this study could be useful tools for clinicians to predict lung metastasis probability and personalize CSS evaluation for patients with MPOSN. [Extracted from the article]

A recent report from the University of Rijeka in Croatia discusses new research on adamantinoma, a rare bone tumor. The study highlights the relationship between adamantinoma and osteofibrous dysplasia, as well as the importance of immunohistochemical staining for accurate diagnosis. The researchers present a case study of an adamantinoma tumor that exhibited different morphological patterns over time, emphasizing the challenges of diagnosing this condition based on a single biopsy. The findings underscore the need for comprehensive evaluation and the use of specific markers in histopathological analysis. [Extracted from the article]

A recent study conducted by researchers at Capital Medical University in Beijing, China, explored the use of esketamine and pregabalin in managing acute postsurgical pain (APSP) in patients who underwent spinal neoplasm resection. The study found that the combination of esketamine and pregabalin effectively reduced the incidence of moderate-to-severe APSP compared to a control group. However, it was noted that the combined treatment increased the risk of mild dissociative symptoms. This research provides valuable insights into potential analgesic strategies for patients undergoing spinal surgery. [Extracted from the article]

A recent report discusses research conducted at the University of Ioannina in Greece on bone neoplasms. The study focused on the use of rotationplasty as a surgical treatment for lower limb bone tumors in young cancer patients. The researchers conducted a systematic review and meta-analysis of studies that assessed the impact of rotationplasty on gait parameters measured by gait analysis. The findings showed that rotationplasty significantly decreased gait velocity, stride length, and cadence compared to healthy individuals. The researchers concluded that rotationplasty is a valid option for managing lower limb bone tumors in young cancer patients, but larger studies are needed to further improve outcomes. [Extracted from the article]

A recent study conducted at the University of Texas Southwestern Medical Center in Dallas has explored the characteristics of a rare malignancy called Adamantinoma-like Ewing sarcoma (ALES). The study found that ALES is a variant of Ewing sarcoma, but unlike most cases, it does not harbor EWSR1 rearrangements. Instead, the study identified FUS rearrangements in all cases of ALES. The tumors were found in various locations, including the sinonasal tract, major salivary glands, and anterior mediastinum. The study highlights the importance of considering ALES in the differential diagnosis of small round cell tumors and tumors with neuroendocrine differentiation. [Extracted from the article]

Researchers at the Cleveland Clinic have conducted a study on Ewing Sarcoma, specifically focusing on a variant called Adamantinoma-like Ewing Sarcoma (ALES). Traditionally, ALES has been considered a variant of Ewing Sarcoma due to similar genetic characteristics, but this study suggests that ALES may actually be a separate entity. The researchers used DNA methylation profiling to compare ALES to conventional Ewing Sarcoma and found distinct differences in the methylation patterns. This finding adds to the evidence that ALES and conventional Ewing Sarcoma should be considered distinct entities. [Extracted from the article]

Desmoplastic adamantinoma-like thymic carcinoma represents an unusual histologic variant of thymic carcinoma that needs to be distinguished from metastases from similar tumors to the mediastinum." Keywords: Adamantinoma; Bone Diseases and Conditions; Bone Neoplasms; Cancer; Carcinomas; Health and Medicine; Musculoskeletal Diseases and Conditions; Oncology; Thymic Cancer; Thymic Carcinoma; Thymoma EN Adamantinoma Bone Diseases and Conditions Bone Neoplasms Cancer Carcinomas Health and Medicine Musculoskeletal Diseases and Conditions Oncology Thymic Cancer Thymic Carcinoma Thymoma 1174 1174 1 10/09/23 20231010 NES 231010 2023 OCT 10 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators publish new report on thymic cancer. [Extracted from the article]

Keywords: Adamantinoma; Bone Diseases and Conditions; Bone Neoplasms; Cancer; Ewing Sarcoma; Health and Medicine; Musculoskeletal Diseases and Conditions; Oncology; Sarcomas EN Adamantinoma Bone Diseases and Conditions Bone Neoplasms Cancer Ewing Sarcoma Health and Medicine Musculoskeletal Diseases and Conditions Oncology Sarcomas 561 561 1 08/14/23 20230815 NES 230815 2023 AUG 15 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- A new study on Ewing sarcoma is now available. Adamantinoma, Bone Diseases and Conditions, Bone Neoplasms, Cancer, Ewing Sarcoma, Health and Medicine, Musculoskeletal Diseases and Conditions, Oncology, Sarcomas. [Extracted from the article]

Bone Diseases and Conditions, Bone Neoplasms, Health and Medicine, Musculoskeletal Diseases and Conditions, Neoplasms, Quality of Life, Skull Base Neoplasms, Skull Neoplasms Keywords: Bone Diseases and Conditions; Bone Neoplasms; Health and Medicine; Musculoskeletal Diseases and Conditions; Neoplasms; Quality of Life; Skull Base Neoplasms; Skull Neoplasms EN Bone Diseases and Conditions Bone Neoplasms Health and Medicine Musculoskeletal Diseases and Conditions Neoplasms Quality of Life Skull Base Neoplasms Skull Neoplasms 3432 3432 1 07/31/23 20230804 NES 230804 2023 AUG 4 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- New study results on skull base neoplasms have been published. [Extracted from the article]

Jacksonville, State:Florida, United States, North and Central America, Adamantinoma, Bone Diseases and Conditions, Bone Neoplasms, Cancer, Ewing Sarcoma, Health and Medicine, Musculoskeletal Diseases and Conditions, Neoplasms, Oncology, Sarcomas Keywords: Jacksonville; State:Florida; United States; North and Central America; Adamantinoma; Bone Diseases and Conditions; Bone Neoplasms; Cancer; Ewing Sarcoma; Health and Medicine; Musculoskeletal Diseases and Conditions; Neoplasms; Oncology; Sarcomas EN Jacksonville State:Florida United States North and Central America Adamantinoma Bone Diseases and Conditions Bone Neoplasms Cancer Ewing Sarcoma Health and Medicine Musculoskeletal Diseases and Conditions Neoplasms Oncology Sarcomas 1072 1072 1 07/03/23 20230704 NES 230704 2023 JUL 4 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Data detailed on Oncology - Ewing Sarcoma have been presented. Keywords for this news article include: Jacksonville, Florida, United States, North and Central America, Adamantinoma, Bone Diseases and Conditions, Bone Neoplasms, Cancer, Ewing Sarcoma, Health and Medicine, Musculoskeletal Diseases and Conditions, Neoplasms, Oncology, Sarcomas, University of Florida. [Extracted from the article]

Keywords: Adamantinoma; Bone Diseases and Conditions; Bone Neoplasms; Cancer; Carcinomas; Diagnostics and Screening; Ewing Sarcoma; Health and Medicine; Mechanoreceptors; Merkel Cell Cancer; Merkel Cell Carcinoma; Merkel Cells; Musculoskeletal Diseases and Conditions; Nervous System; Neurons; Oncology; Peripheral Nervous System; Sarcomas; Sensory Receptor Cells EN Adamantinoma Bone Diseases and Conditions Bone Neoplasms Cancer Carcinomas Diagnostics and Screening Ewing Sarcoma Health and Medicine Mechanoreceptors Merkel Cell Cancer Merkel Cell Carcinoma Merkel Cells Musculoskeletal Diseases and Conditions Nervous System Neurons Oncology Peripheral Nervous System Sarcomas Sensory Receptor Cells 1049 1049 1 05/22/23 20230523 NES 230523 2023 MAY 23 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- New research on Merkel cell cancer is the subject of a new report. For more information on this research see: Adamantinoma-Like Ewing Sarcoma Mimicking Merkel Cell Carcinoma in the Parotid Gland: A Diagnostic Pitfall. [Extracted from the article]

A deformed leg bone from a 76-million-year-old fossil offers the first histologically confirmed example of a malignant tumor diagnosed in a dinosaur. The paleontologic findings could narrow the oncologic search for genomic drivers of osteosarcoma today., (©2020 American Association for Cancer Research.)