Search

The article discusses that patients treated with dupilumab for atopic dermatitis experience musculoskeletal symptoms, including enthesitis, arthritis and tenosynovitis. These symptoms resemble those seen in psoriatic arthritis and peripheral spondyloarthritis; clinicians have been managing them with conservative approaches like adjusting the frequency of dupilumab administration; and important for prescribers to be aware of these potential side effects and monitor patients accordingly.

The article focuses on musculoskeletal disorders (MSDs) in professional musicians and the need for greater awareness and early detection of these conditions. Topics include the high prevalence of pain among orchestra musicians, the psychosocial risk factors associated with MSDs, and the importance of evaluating the work environment and providing prompt treatment to alleviate pain.

A Swedish study published in JAMA Network Open suggests that poorer physical function, rather than lower bone mineral density (BMD), may be the main reason for the increased fracture risk in older women with type 2 diabetes (T2D). The study, conducted by Dr. Mattias Lorentzon and colleagues, found that women with T2D had higher BMD and better bone microarchitecture but poorer physical performance and higher fracture risk compared to women without diabetes. The researchers recommend monitoring physical function to identify diabetes patients at high risk of fractures and improving physical function to reduce fracture risk. [Extracted from the article]

A recent study conducted in Vienna found that nearly 70% of patients with hand osteoarthritis (OA) had tendon involvement, but this did not significantly impact hand function or pain. The study used ultrasonography to assess tendon damage and tenosynovitis in 86 patients with hand OA and compared them to a control group. The results showed that tendon damage was more common in the flexor tendons, while tenosynovitis was more prevalent in the extensor tendons. The study suggests that physicians should consider the high prevalence of tendon involvement in hand OA and perform sonographic examinations if there is clinical suspicion. However, the study had limitations, such as the lack of a standardized clinical examination and a preferred method for detecting tendon damage. [Extracted from the article]

A recent study published in The Lancet found that a smartphone app delivering acceptance and commitment therapy (ACT) can effectively manage symptoms of fibromyalgia. The study involved 275 adult patients with fibromyalgia who were randomly assigned to either the digital ACT group or an active control group for 12 weeks. The digital ACT group showed significant improvements in overall well-being and reductions in pain, fatigue, sleep issues, and depression compared to the control group. The study suggests that digital ACT may be a viable treatment alternative for patients with fibromyalgia. However, it is important to note that the study had limitations, such as a predominantly female and White study population, and the long-term benefits of digital ACT have not yet been established. [Extracted from the article]

A recent study found that a significant number of patients with osteoarthritis (OA) and rheumatoid arthritis (RA) also screened positive for anxiety, depression, and/or fibromyalgia. The study analyzed data from 366 OA patients and 488 RA patients at an academic medical center. The prevalence of these comorbidities was linked to poorer patient status measures. The authors recommend routine screening for these conditions in clinical practice to better inform healthcare professionals about patient status, prognosis, and treatment response. However, it is important to note that the study had limitations, such as being cross-sectional and lacking information on certain clinical variables. [Extracted from the article]

A recent study published in Osteoarthritis and Cartilage suggests that exercise therapy is more effective for individuals with knee osteoarthritis who have experienced symptoms for less than one year. The study, which analyzed data from 10 randomized controlled trials, found that exercise therapy led to improvements in pain and physical function in both the short-term and long-term. Participants with symptom durations of less than one year or less than two years showed greater benefits from exercise therapy compared to those with longer symptom durations. The authors recommend encouraging exercise therapy as early as possible to potentially slow disease progression. However, the study had limitations, including a lack of information on the severity of osteoarthritis and a relatively short follow-up time. The study was supported by the Netherlands Organisation for Health Research and Development. [Extracted from the article]

A recent study conducted in Vienna found that nearly 70% of patients with hand osteoarthritis (OA) had tendon involvement, but this did not significantly impact hand function or pain. The study used ultrasonography to assess tendon damage and tenosynovitis in 86 patients with hand OA and compared them to a control group. The results showed that tendon damage was more common in the flexor tendons, while tenosynovitis was more prevalent in the extensor tendons. The study suggests that physicians should consider the high prevalence of tendon involvement in hand OA and perform sonographic examinations if there is clinical suspicion. However, the study had limitations, such as the lack of a standardized clinical examination and a preferred method for detecting tendon damage. [Extracted from the article]

A recent study conducted at an academic medical center found that a significant number of patients with osteoarthritis (OA) and rheumatoid arthritis (RA) screened positive for anxiety, depression, and/or fibromyalgia. These comorbidities were associated with poorer patient status measures, indicating the need for routine screening in clinical practice. Among the patients with OA, 40.4% screened positive for at least one of the three indices indicating patient distress, while the proportion was 36.3% among patients with RA. The study suggests that incorporating screening for these conditions into routine clinical care can provide valuable information for healthcare professionals. However, it is important to note that the study had some limitations, such as its cross-sectional design and the lack of information on certain clinical variables. [Extracted from the article]

The Food and Drug Administration (FDA) has approved ustekinumab-ttwe (Pyzchiva) as a biosimilar to ustekinumab (Stelara) for the treatment of multiple inflammatory conditions. The FDA has provisionally determined that Pyzchiva may be interchangeable with the reference product, but this designation will not take effect until the interchangeability exclusivity period for the first approved biosimilar, ustekinumab-auub (Wezlana), expires. Pyzchiva is indicated for the treatment of moderate to severe plaque psoriasis, active psoriatic arthritis, Crohn's disease, and ulcerative colitis. It will be commercialized by Sandoz in the United States and is expected to launch in February 2025. [Extracted from the article]

A recent study published in JAMA Dermatology found that individuals with severe acne are often considered less attractive, less worthy of friendship, and less likely to be hired for a job compared to those without acne. The study surveyed over 1300 individuals and used digitally enhanced stock photographs to assess attitudes towards acne. The results showed that participants were significantly less comfortable being friends with or hiring someone with severe acne, and also held negative stereotypes about individuals with acne. The study highlights the persistent stigma associated with acne and the need for interventions to reduce stigmatizing attitudes and improve access to care. [Extracted from the article]

The article focuses on a Dutch study presented at the European Congress of Rheumatology, which found that rheumatic disease is not a significant risk factor for long COVID. It discusses about patients with inflammatory rheumatic diseases (iRD) reported symptoms resembling long COVID; the data suggest that many of these symptoms can be attributed to the underlying rheumatic disease; and patients with iRD are more susceptible to long COVID due to a higher risk of severe disease.

The article focuses on the health condition of the patient named Magglio, who was diagnosed with Pompe disease and son of Becka Boscarino in the U.S. It provides overview of the different treatment undergone by Magglio and the complications he experienced from the medications. It also mentions how the patient's condition has triggered calls for pharmaceutical companies to double check the therapeutic uses and complications of their products.

Reports the convening of an ergonomics advisory committee in the U.S. Occupational Safety and Health Administration. Solution to musculoskeletal disorders (MSD); Advisory on the Department of Labor on the improvement of science and training in the prevention of MSD; Criticism of Democratic legislators on the department.

The article reports on the study by researcher Jonathan H. Tobias with his colleagues published in the journal "Arthritis Care & Research," which reveals that children with hypermobile knees, ankles, and shoulders are at risk of musculoskeletal pain.

The article reports that the European Federation of National Associations of Orthopaedics and Traumatology (EFORT) partnered with the Fit for Work Coalition in an effort to keep people with musculoskeletal disorders (MSDs) in work.

The article reports on the move of the Occupational Safety and Health Administration (OSHA) of the U.S. in pulling back and delaying the musculoskeletal disorders (MSD) record-keeping rule.

The article reports on the findings by health experts that human growth hormones (HGH) can offer questionable benefits and big risks to users who are trying to add muscle in the U.S. Legally prescribed for three rare diseases, HGH can cause joint and muscle pain and carpal tunnel syndrome and may accelerate cancer and cause diabetes. Thomas Perls, professor of medicine at Boston University School of Medicine, said their studies have shown that HGH use can cause a small increase in muscle mass.

The article reports on a subpoena received by Biomet Inc. from the U.S. Justice Department regarding the products sold by its EBI LP subsidiary. In a Securities and Exchange Commission filing, the company said that the subpoena sought documents relating to a limited number of products manufactured and sold by EBI since January 1999. Biomet manufactures and markets musculoskeletal-therapy products.

Discusses the importance of office ergonomics in the prevention of musculoskeletal disorders. Areas of work addressed by office ergonomics; Definition of musculoskeletal disorders; Types of musculoskeletal disorders.

Discusses a syndrome termed fibromyalgia, the hallmarks of which are widespread muscular pain and debilitating fatigue. What it is; Possible causes; Treatment.

Presents a schedule of Congressional hearings on issues of interest to educators and scientists in the U.S. from July 19 to August 4, 1982. Nomination of Gary L. Jones as under secretary of the Department of Education; Establishment of the National Institute on Arthritis and Musculoskeletal Diseases; Formation of the Carl Albert Congressional Research and Studies Center Endowment.