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The article discusses the potential of nasal drug delivery as a non-invasive and efficient method for administering medications. It discusses that nasal cavity offers a large surface area and rapid absorption, making it an attractive target for drug delivery; nasal drug delivery has shown promise in delivering therapies to the brain; providing a direct pathway for treating central nervous system disorders; and has potential applications in vaccines and other treatments.

A week dominated by political drama in Washington endedFriday with the specter of a deepening trade war, sending U.S. stocks toa three-week low and bolstering demand for haven assets. Friday brought the latest drama after a reportthat the Trump administration is considering sweeping limits tocapital-market investments, forcing Wall Street to assess the impact onpotentially billions of dollars of assets. The company was founded in 2008 todevelop therapeutics for the treatment of various cancers through theuse of mRNA-based drugs, chimeric antigen receptor T-cells, checkpointimmunomodulators, as well as targeted cancer antibodies andsmall-molecule drugs. [Extracted from the article]

2021 JUN 14 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators discuss new findings in spinal muscular atrophy. According to news reporting originating [...]

Reports that the World Health Organization said the health ministries of Afghanistan, India and Pakistan are on target to wipe out polio by the end of 2005.

Reports that an Irishman in his 20s was found to have variant Creutzfeldt-Jakob disease, which is contracted from eating cattle infected with mad cow disease, being the first indigenous case of the incurable and degenerative brain disorder in the country.

Introduction Quality surveillance is critical to the control and elimination of vaccine-preventable diseases (VPDs). A key strategy for enhancing VPD surveillance, outlined in the World Health Organization (WHO) Global Framework [...]

Rabies is a viral infection of the central nervous system, usually contracted from the bite of an infected animal, and is nearly always fatal without proper postexposure prophylaxis (PEP) (1). [...]

'Oropouche fever is the second most frequent arboviral infection in Brazil, surpassed only by dengue. Oropouche virus (OROV) causes large and explosive outbreaks of acute febrile illness in cities and [...]

'CD4 T cell activation during peripheral infections not only is essential in inducing protective CD8 T cell memory but also promotes CD8 T cell function and survival. However, the contributions [...]

'Chemokine (C-X-C motif) receptor 4 (CXCR4) from orange-spotted grouper (Epinephelus coioides) was identified and characterized in this study. gCXCR4 shared common features in protein sequence and predicted structure of CXCR4 [...]

'Congenital cytomegalovirus (CMV) infection is the leading cause of non-hereditary congenital sensorineural hearing loss (SNHL). The natural course and the pathophysiology of inner ear lesions during human fetal CMV infection [...]

Fresh data on Central Nervous System Infections are presented in the report 'Treatment of mice with human monoclonal antibody 24h after lethal aerosol challenge with virulent Venezuelan equine encephalitis virus [...]

'After virus infection, cytotoxic T lymphocytes (CTLs) divide rapidly to eradicate the pathogen and prevent the establishment of persistence. The magnitude of an antiviral CTL response is thought to be [...]

'The entry of anti-infectives into the central nervous system (CNS) depends on the compartment studied, molecular size, electric charge, lipophilicity, plasma protein binding, affinity to active transport systems at the [...]

'Tumors of the brain and spinal cord (central nervous system, CNS) are rare when compared with other sites and other diseases that can affect the length of an individual's life. [...]

Current study results from the report, 'Regulation of peripheral inflammation by the central nervous system,' have been published. 'In inflammatory disorders such as rheumatoid arthritis, cytokines and danger signals are [...]

'The human immunodeficiency virus type 1 (HIV-1) protein transactivator of transcription (Tat) is believed to play a critical role in mediating central nervous system (CNS) pathology in pediatric HIV-1 infection. [...]

(CW HENDERSON PUBLISHER www.newsfile.com) -- The transplantation of neural stem cells may be beneficial for various diseases of the central nervous system, researchers suggest. Many central nervous system (CNS) diseases, [...]

Reports that a case of polio has been detected in Indonesia, according to World Health Organization (WHO) officials, indicating that an outbreak spreading from northern Nigeria since 2003 has reached the world's fourth most populous country. How the virus was found in a village on the island of Java; Speculation on how the virus got there; Recommendation by officials that Indonesia immediately vaccinate five million children on the western end of Java; Observation that polio is now found almost exclusively in Muslim countries or regions; Outlook for the WHO's goal of eradicating polio by the end of 2005; Evidence of widespread circulation of the virus.

The article reports that Scottish nurse Pauline Cafferkey, who recovered from Ebola after her initial infection in Sierra Leone, has been rehospitalized at the Royal Free Hospital in England in 2015, with experts stated the virus re-emerged to cause a severe disorder to her central nervous system.

The author discusses the continuing struggle of the Pakistani government campaign against polio disease following the research findings wherein a total of 94 cases of polio have occurred in North Waziristan and the government's effort to conduct vaccination among children.

The article argues on multiple sclerosis (MS), an autoimmune disease which affects the fibers of central nervous systems of the people.

The article discusses the move of the Massachusetts Department of Health to issue hundreds of pages of documents detailing a history of violations at New England Compounding Center, whose tainted medicine has caused a nationwide meningitis outbreak. The firm's habit of allowing doctors' offices to fax orders for medicine without names of specific patients is among the most frequently cited problems. Barry J. Cadden, the firm's chief pharmacist and co-owner, is profiled.

A new meningococcal vaccine, just introduced in West Africa, has produced very encouraging results, according to the public-private partnership coordinating its distribution. This year's meningitis season is almost over, and there have been only four confirmed cases of meningitis A in Burkina Faso, the first country to offer the shot to all citizens under 30 (above, a child was vaccinated there). Three infections were in people from Togo, where the vaccine is not used; they had crossed the border for care. The fourth was in a Burkinan who was not vaccinated. [ABSTRACT FROM AUTHOR]

International NEW MENINGITIS VACCINE [ABSTRACT FROM AUTHOR]

JOHANNESBURG -- For over a century, epidemics of bacterial meningitis have swept across Africa, arriving with the dry harmattan winds to kill with terrifying speed. But on Monday, a drive starts to inoculate tens of millions of West Africans with a new vaccine in what scientists hope will be the beginning of the end of ravaging meningitis epidemics. The aim is for these immunization campaigns to spread from Senegal in the west to Ethiopia in the east, bringing the disease under control and saving an estimated 150,000 lives by 2015 in a belt of 25 nations that girds the continent. [ABSTRACT FROM AUTHOR]

ATLANTA -- Federal vaccine advisers recommended on Wednesday that 16-year-olds be given a booster dose of a vaccine against meningococcal meningitis and that people ages 11 to 64 get a booster to protect against whooping cough, diphtheria and tetanus. The reason for the meningitis recommendation is that two popular vaccines against the disease do not seem to work as well as hoped. Instead of providing 10 years of protection, they may work for only five years or less. [ABSTRACT FROM AUTHOR]

The article presents questions and answers related to health including the correlation of broken heart syndrome and high blood pressure and Creutzfeldt-Jakob disease.

Health officials have confirmed three cases of West Nile virus this season among New York City residents. The health department says a 61-year-old Bronx man was the first New Yorker to contract the virus this season; he was hospitalized. It says the man also had meningitis. Two Staten Island women, one 74 years old and the other 46, also have contracted the virus. Both were hospitalized. [ABSTRACT FROM AUTHOR]

The article provides an answer to a question related to post-polio syndrom.

IT started with an odd sensation in her right hand and a feeling of exhaustion so profound she could hardly get through an hour of work, let alone a full day. After numerous tests and countless doctors' visits, Natasha Frechette, then 27, learned she had multiple sclerosis, a disease that attacks the central nervous system and can cause numbness, blindness and eventual paralysis. [ABSTRACT FROM PUBLISHER]

MENINGITIS An outbreak of meningitis in Nigeria has killed 333 people in the past three months, the health minister said Wednesday. The minister, Babatunde Osotimehin, said that 5,323 cases had been recorded in 22 of the country's 36 states. [ABSTRACT FROM PUBLISHER]

One soldier is dead of meningitis at Fort Leonard Wood and a second is ''very seriously ill,'' officials at the Army base in southern Missouri said. Officials released few details and did not identify either soldier. Both cases involved noncontagious forms of meningitis, the authorities said. The two soldiers were members of the same unit, but no connection has been found between the cases. ''Although difficult to comprehend, all clinical data show these cases are unrelated and purely coincidental,'' said Lt. Col. John Lowery, deputy commander for clinical services at the base. The first soldier died after meningitis was diagnosed on Feb. 5. The second soldier is a 28-year-old who received a diagnosis of strep pneumonia leading to meningitis on Friday. The authorities said that although the illnesses were non-contagious forms, they were ''heightening awareness'' of preventive measures. The Centers for Disease Control and Prevention, the Surgeon General's Office and the Army Medical Command are reviewing the cases. Meningitis kills about 300 people in the United States each year. [ABSTRACT FROM PUBLISHER]

A few things gleaned from watching ''Three Movements'': ''You can't be a vicious bitch when you get polio. It's a rule.'' [ABSTRACT FROM PUBLISHER]

A highly drug-resistant germ has become a common cause of meningitis, pneumonia and other life-threatening conditions in young children. The culprit -- a strain of strep bacteria -- can conquer almost all antibiotics in pediatrics, and has dodged a vaccine otherwise credited with causing the number of serious infections in children to plummet. Since 2000, American toddlers have been immunized against Streptococcus pneumoniae, or pneumococcus, an organism that preys largely on children younger than 5 and the elderly. Pneumococcal meningitis can be fatal, and survivors are often left with deafness and other lifelong neurological problems. [ABSTRACT FROM PUBLISHER]

In 1929, my Uncle Philly, who worked the stadium snack bars as a lifelong employee of the concessionaire Harry M. Stevens, arranged for my mother, then 12, to have her picture taken with the Babe. That was the beginning of his taking ''the chickens,'' his raft of nieces and nephews from my mother's generation and mine, to the ballpark. Philly, who was unmarried, spent Yankees seasons at the ballpark and winters at the track in Hialeah Park, and had the perfect life. But he could never remember our names, which is why he called each of us Chicken. In the summer of 1962, I was about to be sent to sleep-away camp in Maine for the first time while my mother was hospitalized with spinal meningitis. I was an understandably worried girl. Philly kindly took my mind off my troubles by bringing me with him to the park. He'd tip one of the ushers to watch me while he tended to the beer and dogs. That was the summer I learned how to stop worrying. [ABSTRACT FROM PUBLISHER]

As a child, the road cyclist Amber Neben was admitted to a California hospital with meningitis. Doctors instructed her parents to prepare for the worst, telling them the odds were stacked against her survival. ''Obviously, they didn't know Amber very well,'' Jason, her husband of 11 years, wrote in an e-mail message this week. [ABSTRACT FROM PUBLISHER]

The article discusses research being done on human parechoviruses and its association with meningitis and sepsis-like illness in children. It references a study by Kimberley S. M. Benschop and colleagues published in a 2008 issue of the journal "Clinical Infectious Diseases." Researchers found that human parechovirus types are capable of infecting the central nervous system (CNS). They also found that the use of certain polymerase chain reaction assays to identify human parechovirus may lessen the duration of antibiotic use and hospitalization.

The article reports that the meningitis vaccine Menveo by Novartis AG performed well in a clinical trial against several types of meningitis bacteria. According to the U.S. Centers for Disease and Control Prevention, meningitis occur between 1,400 and 2,800 cases each year and 10% to 14% of patients die as a result. In the trial, 2,100 adolescent received a single vaccination of either Menveo or Sanofi-Aventis's Menactra, and a higher percentage of those given Menveo experienced a strong immune response against type A, W-135 and Y bacteria strains.

The article offers news briefs related to several developments of the metropolitan areas of the U.S. Tavin Alves of Manhattan, New York City was hurt by a gunfire while he looked out of his apartment window. Four new express trains will begin running in the new Prudential Center in Newark, New Jersey from October 2007. Erin Ortiz, a New Hampton college student died on October 8, 2007, of bacterial meningitis.

The article offers the author's experience of treating a girl named Shana who was a patient of meningitis. She explains that the 19 year old girl who was on the palliative treatment was later declared brain dead by her. She also shares her experience of talking with the patient's mother Madeline, and comments on her profession.

Reports on the U.S. Centers for Disease Control and Prevention's confirmation of cases of neurological disorder among recipients of a meningitis vaccine made by a unit of Sanofi-Aventis SA.

The article presents the author's experience while suffering from chronic meningococcemia.

The article focuses on the organization of the theater festival "Eurofest," initiated by Edward Einhorn which is intended for those who have neurological problems at the Theater 5 in New York City. The actives featured include the 13 plays for the following five days of celebration , seminars and panel discussions. Theatrical presentations include a play that tells about Creutzfeldt-Jacob disease, and a puppet show that conveys about Asperger's syndrome.