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The Mail & Guardian said Friday that it had underestimated ''the depth of anger ignited'' by a cartoon it published last week that depicted the Prophet Muhammad lying on a psychiatrist's couch with a thought bubble over his head that said, ''Other prophets have followers with a sense of humor!'' The weekly said it regretted ''the sense of injury it caused many Muslims.'' The cartoon was by Jonathan Shapiro, known as Zapiro, whose sharp satiric pen has gouged many a politician. [ABSTRACT FROM PUBLISHER]