Search

Your search keyword '"Zhang, Tong"' showing total 2 results
Start Over Author "Zhang, Tong" Publication Year Range Last 3 years Publication Type Periodicals Publisher georg thieme verlag stuttgart
2 results on '"Zhang, Tong"'

1. Synthesis of Aryl Carboxylic Acids through Ambient Electro-oxidation of Arylacetylenes.

Author

Yuan, Hongyan, Sun, Manxin, Zhang, Tong, Wu, Guohao, and Zhang, Yanhua

Subjects
CARBOXYLIC acids, TRANSITION metal catalysts, ACID catalysts, ORGANIC compounds, RESEARCH personnel
Abstract

This article discusses a new method for synthesizing aryl carboxylic acids from arylacetylenes through ambient electro-oxidation. The method eliminates the need for transition metal catalysts and extra acids/bases, making it a mild and environmentally friendly process. The reaction conditions and substrate scope are explored, and the method exhibits good functional group tolerance and high yields. The article also provides information on various organic compounds, including their physical properties and spectroscopic data, which can be useful for researchers studying these compounds. The authors acknowledge the support of Nanjing Tech University and provide a link to additional supporting information. [Extracted from the article]

Published
2024
Full Text
View/download PDF

2. Metabolite Profiling of Swertia cincta Extract in Rats and Pharmacokinetics Study of Three Bioactive Compounds Using UHPLC-MS/MS.

Author

Ye, Xiaoyin, Zhang, Tong, and Han, Han

Subjects
*BIOLOGICAL models, *HERBAL medicine, *IN vivo studies, *LIQUID chromatography, *ANIMAL experimentation, *LIVER, *CHOLECYSTITIS, *ORGANIC compounds, *QUANTITATIVE research, *CELLULAR signal transduction, *RATS, *MASS spectrometry, *RESEARCH funding, *MOLECULAR structure, *JAUNDICE, *CHINESE medicine, *METABOLITES, *THERAPEUTICS
Abstract

Swertia cincta , a plant of the genus Swertia in Gentianceae, has "heat-clearing" and detoxifying effects that normalize the gallbladder function in the treatment of jaundice. Although numerous studies on Swertia cincta have been performed, the absorption and pharmacokinetic behaviors remain unclear. In this study, the compounds of Swertia cincta in serum, bile, feces, and urine of rats were analyzed using a ultra-high-performance liquid chromatography-tandem mass spectrometry. A total of 9 prototype components and 48 metabolites were detected in biological samples. Furthermore, we determined the main components absorbed in the blood of Swertia cincta and established a method for simultaneously determining these components (sweroside, swertiamarin, and gentiopicroside) in positive ionization mode within 6 min. The quantitative method was successfully applied for the multiple-component pharmacokinetic study of Swertia cincta. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results