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Large Language Models (LLMs) are becoming ubiquitous to create intelligent virtual assistants that assist users in interacting with a system, as exemplified in marketing. Although LLMs have been discussed in Modeling & Simulation (M&S), the community has focused on generating code or explaining results. We examine the possibility of using LLMs to broaden access to simulations, by enabling non-simulation end-users to ask what-if questions in everyday language. Specifically, we discuss the opportunities and challenges in designing such an end-to-end system, divided into three broad phases. First, assuming the general case in which several simulation models are available, textual queries are mapped to the most relevant model. Second, if a mapping cannot be found, the query can be automatically reformulated and clarifying questions can be generated. Finally, simulation results are produced and contextualized for decision-making. Our vision for such system articulates long-term research opportunities spanning M&S, LLMs, information retrieval, and ethics., Comment: To appear in proceedings of the 2024 Winter Simulation Conference

Epistemology is the branch of philosophy that deals with gaining knowledge. It is closely related to ontology. The branch that deals with questions like "What is real?" and "What do we know?" as it provides these components. When using modeling and simulation, we usually imply that we are doing so to either apply knowledge, in particular when we are using them for training and teaching, or that we want to gain new knowledge, for example when doing analysis or conducting virtual experiments. This paper looks at the history of science to give a context to better cope with the question, how we can gain knowledge from simulation. It addresses aspects of computability and the general underlying mathematics, and applies the findings to validation and verification and development of federations. As simulations are understood as computable executable hypotheses, validation can be understood as hypothesis testing and theory building. The mathematical framework allows furthermore addressing some challenges when developing federations and the potential introduction of contradictions when composing different theories, as they are represented by the federated simulation systems., Comment: MODSIM World 2013

The Modeling and Simulation Community successfully developed and applied interoperability standards like the Distributed Interactive Simulation (DIS) protocol (IEEE 1278) and the High Level Architecture (HLA) (IEEE 1516). These standards were applied for world-wide distributed simulation events for several years. However, this paper shows that some of the assumptions and constraints underlying the philosophy of these current standards are not valid for Medical Simulation Systems. This paper describes the standards, the philosophy and the limits for medical applications and recommends necessary extensions of the standards to support medical simulation.