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There is a critical need for standard approaches to assess, report, and compare the technical performance of genome-scale differential gene expression experiments. We assess technical performance with a proposed "standard" dashboard of metrics derived from analysis of external spike-in RNA control ratio mixtures. These control ratio mixtures with defined abundance ratios enable assessment of diagnostic performance of differentially expressed transcript lists, limit of detection of ratio (LODR) estimates, and expression ratio variability and measurement bias. The performance metrics suite is applicable to analysis of a typical experiment, and here we also apply these metrics to evaluate technical performance among laboratories. An interlaboratory study using identical samples shared amongst 12 laboratories with three different measurement processes demonstrated generally consistent diagnostic power across 11 laboratories. Ratio measurement variability and bias were also comparable amongst laboratories for the same measurement process. Different biases were observed for measurement processes using different mRNA enrichment protocols., Comment: 65 pages, 6 Main Figures, 33 Supplementary Figures

In this paper, two classes of exact analytic time-dependent soultion of magnetic annihilation for incompressible magnetic fluid, have been obtained by solving the magnetohydrodynamic (MHD) equations directly. The solutions derived here possess scaling property with time $t$ as the scale factor. Based on these two solutions, we find that, for some given inflow fields, the evolution of the annihilating magnetic field can be described by the solutions of certain ordinary differential equations whose variables are dilated simply by time $t$. The relevant evolution characteristics in the process of magnetic annihilation are also revealed., Comment: 16 pages, Latex file, 7 EPS figures