1. Targeted Therapies for Hepatocellular Carcinoma Treatment: A New Era Ahead—A Systematic Review.
- Author
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Damaskos, Christos, Garmpis, Nikolaos, Dimitroulis, Dimitrios, Garmpi, Anna, Psilopatis, Iason, Sarantis, Panagiotis, Koustas, Evangelos, Kanavidis, Prodromos, Prevezanos, Dionysios, Kouraklis, Gregory, Karamouzis, Michail V., Marinos, Georgios, Kontzoglou, Konstantinos, and Antoniou, Efstathios A.
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HEPATOCELLULAR carcinoma , *CHRONIC hepatitis B , *HEPATITIS C virus , *CHRONIC hepatitis C , *VIRUS diseases - Abstract
Hepatocellular carcinoma (HCC) remains one of the most common malignancies and the third cause of cancer-related death worldwide, with surgery being the best prognostic tool. Among the well-known causative factors of HCC are chronic liver virus infections, chronic virus hepatitis B (HBV) and chronic hepatitis virus C (HCV), aflatoxins, tobacco consumption, and non-alcoholic liver disease (NAFLD). There is a need for the development of efficient molecular markers and alternative therapeutic targets of great significance. In this review, we describe the general characteristics of HCC and present a variety of targeted therapies that resulted in progress in HCC therapy. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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