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In this paper the extraction of curcuminoids from Curcuma longa roots has been carried out. In particular, the interest was focused on curcumin as powerful anti-tumoral that would result from its ability to induce apoptosis in cancer cells without cytotoxic effects on healthy cells. The latter could in fact interfere with the activity of the transcription factor TNF alpha and beta (Tumor Necrosis Factor) which has been linked to a number of inflammatory diseases and even cancer. The fast solid-liquid dynamic extractor (RSLDE), the Naviglio Extractor (NE) is an innovative technology allowing to drain quickly, than other extraction techniques currently exist, the solid matrices containing substances extractable in an organic solvent or inorganic and their mixtures. This innovative technique was used as an alternative to conventional solid-liquid extraction techniques like as maceration (or infusion) and percolation because it allows to use only water as extracting liquid at room temperature and it ends its extractive cycle in minimal time of contact between solid and liquid such a way extracted molecules are not undergone to chemical degradation. [ABSTRACT FROM AUTHOR]