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1. Proteoforms: A New Separation Dilemma.

Author

Regnier, Fred E. and JinHee Kim

Subjects
*PROTEIN synthesis, *HUMAN genome, *PROTEIN metabolism, *HUMAN chromosomes, *ANALYTICAL chemistry
Abstract

The article discusses the role of proteoforms, which are structural isoforms and have different biological functions in the human genome. Proteoforms arise from a single gene and they are cognates with multiple, identical structural features. During protein synthesis, a protein-coding gene provides the blueprint for a family of structural isoforms arising from small, regulated variations in their synthesis.

Published
2017

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