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The article focuses on the importance of distinguishing secondary glaucoma types, such as pseudoexfoliative syndrome, in order to provide proper care. Topics discussed include the genetic considerations, highlighting the role of the LOXL-1 gene and elastin in the pathophysiology of pseudoexfoliative syndrome, and the clinical ramifications, detailing the impact on ocular structures and the increased risk of glaucoma development due to elastin and lysyl oxidase relationship defects.

The article focuses on the approaches for managing pseudoexfoliative glaucoma (PXG). Topics discussed include the differences between primary open-angle glaucoma (POAG) and PXG, the higher risk of individuals with lysyl oxidase-like 1 (LOXL1) to develop PXG, and the possibility for PXG to affect organ system and result to complications such an increased risk of coronary artery disease, and abdominal aneurysms.

The article presents information on exfoliation glaucoma (XFG) exfoliation syn­drome (XFS) and pseudoexfoliation (PEX) caused by deposition of a protein-like material within the anterior segment of the eye. The article also highlights the importance of secondary glaucoma diagnosis and factors associated with XFS including variants of the gene lysyl oxi­dase-like 1 (LOXL). Additional topics include Ocular risks due to pigment dispersion age related cataract from exfoliation and treatment.