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Accurate segmentation of knee cartilage in MR images is crucial for early diagnosis and treatment of knee conditions. Manual segmentation is time-consuming, leading researchers to explore automatic deep learning methods. However, the choice between 2D and 3D networks for organ segmentation remains debated. In this paper, we propose a hybrid 2D and 3D deep neural network approach, named UVNet, which combines the strengths of both techniques to enhance segmentation performance. Within this network structure, the 3D segmentation network serves as the backbone for feature extraction, while the 2D segmentation network functions as an information supplement network. Local and global MIP images are generated by employing various maximum intensity projection modes of knee MRI volumes as input for the information supplement network. By constructing a local and global MIP feature fusion module, the supplementary information obtained from the 2D segmentation network is fully integrated into the backbone network. We assess the quality of the proposed method using the Osteoarthritis Initiative (OAI) dataset and the 2010 Grand Challenge Knee Image Segmentation (SKI-10) dataset, comparing it to the Baseline Network and other advanced 2D and 3D segmentation methods. The experiments demonstrate that UVNet achieves competitive performance in the aforementioned two cartilage segmentation tasks. [ABSTRACT FROM AUTHOR]

The task of cell segmentation in microscope images is difficult and popular. In recent years, deep learning-based techniques have made incredible progress in medical and microscopy image segmentation applications. In this paper, we propose a novel deep learning approach called Residual-Atrous MultiResUnet with Channel Attention Mechanism (RAMRU-CAM) for cell segmentation, which combines MultiResUnet architecture with Channel Attention Mechanism (CAM) and Residual-Atrous connections. The Residual-Atrous path mitigates the semantic gap between the encoder and decoder stages and manages the spatial dimension of feature maps. Furthermore, the Channel Attention Mechanism (CAM) blocks are used in the decoder stages to better maintain the spatial details before concatenating the feature maps from the encoder phases to the decoder phases. We evaluated our proposed model on the PhC-C2DH-U373 and Fluo-N2DH-GOWT1 datasets. The experimental results show that our proposed model outperforms recent variants of the U-Net model and the state-of-the-art approaches. We have demonstrated how our model can segment cells precisely while using fewer parameters and low computational complexity. [ABSTRACT FROM AUTHOR]