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Previously, single classification models were mainly studied to classify human protein cell images, i.e., to identify a certain protein based on a set of different cells. However, a classifier can identify only one protein, in fact, a single cell usually consists of multiple proteins, and the proteins are not completely independent of each other. In this paper, we build a human protein cell classification model by multi-label learning. The logical relationship and distribution characteristics among the labels are analyzed to determine the different proteins contained in a set of different cells (i.e., containing multiple elements in the output space). In this paper, using human protein image data, we conducted comparison experiments on pre-trained Xception and InceptionResnet V2 to optimize the two models in terms of data augmentation, channel settings, and model structure. The results show that the Optimized InceptionResnet V2 model achieves high performance in the classification task. The final accuracy of the Optimized InceptionResnet V2 model we obtained reached 96.1%, which is a 2.82% improvement relative to that before the optimized model. [ABSTRACT FROM AUTHOR]

Accurate segmentation of knee cartilage in MR images is crucial for early diagnosis and treatment of knee conditions. Manual segmentation is time-consuming, leading researchers to explore automatic deep learning methods. However, the choice between 2D and 3D networks for organ segmentation remains debated. In this paper, we propose a hybrid 2D and 3D deep neural network approach, named UVNet, which combines the strengths of both techniques to enhance segmentation performance. Within this network structure, the 3D segmentation network serves as the backbone for feature extraction, while the 2D segmentation network functions as an information supplement network. Local and global MIP images are generated by employing various maximum intensity projection modes of knee MRI volumes as input for the information supplement network. By constructing a local and global MIP feature fusion module, the supplementary information obtained from the 2D segmentation network is fully integrated into the backbone network. We assess the quality of the proposed method using the Osteoarthritis Initiative (OAI) dataset and the 2010 Grand Challenge Knee Image Segmentation (SKI-10) dataset, comparing it to the Baseline Network and other advanced 2D and 3D segmentation methods. The experiments demonstrate that UVNet achieves competitive performance in the aforementioned two cartilage segmentation tasks. [ABSTRACT FROM AUTHOR]