1. Genome Editing for Neurodegenerative Diseases : From Concept to Clinical Trials
- Author
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Sandeep Kumar Singh, Amarish Kumar Yadav, Burkhard Poeggeler, George Perry, Sandeep Kumar Singh, Amarish Kumar Yadav, Burkhard Poeggeler, and George Perry
- Abstract
Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases. - Covers basic mechanisms of genome-editing tools and their therapeutic potential - Highlights current research progress and therapeutic strategies to use genome-editing tools against neurodegenerative diseases - Includes research on genome-editing tool development, from basic concept to clinical trials
- Published
- 2024