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This book is a compact clinical introduction to Lyme borreliosis for physicians of all specialties who care for patients with suspected B. burgdorferi infection, whether in hospital or general practice. The book provides a great deal of practice-oriented information on symptomatology, diagnosis, treatment, and prophylaxis with a special emphasis on the situation in Europe. At the same time, it describes contemporary scientific knowledge in as much detail as is required in order to understand the pathogenetic relationships and their relevance to medical care. The authors are members of an interdisciplinary expert group of epidemiologists, biologists, microbiologists, and clinicians who have been working in the area of tick-borne diseases for many years. The personal experience of each of the authors, accumulated through their daily work with patients in special clinics or by confrontation with complicated questions in basic research, epidemiology, and laboratory diagnostics of Lyme borreliosis, represents an important mainstay of the book. Written from the perspective of clinical management and practical problem-solving, this topical monograph will assist clinicians in meeting diagnostic challenges and providing appropriate medical aid to patients with Lyme borreliosis.

From the foreword by world-leading Lyme expert Joseph J. Burrascano, Jr., MD:A detailed and thoughtful road map is sorely needed. And it is in this context that I am so pleased that we have this book by Dr. Kinderlehrer. I wish I'd had a book like this back in the day to guide me! It covers just about everything—the infections, diagnostic tests, treatments, and yes, the all-important terrain. It gives the reader an in-depth, but easily understandable, guide through the many subtleties of tick-borne illnesses. I am impressed with the knowledge presented and grateful for this information, which has helped so many people recover from chronic illness.To anyone touched by tick-borne diseases, be they a patient, a caregiver, loved one, or health practitioner, this book is a must-read. It will serve as a continuing reference as it gets read and reread to assimilate all it has to offer. I congratulate Dr. Kinderlehrer and thank him for this most impressive work.The ultimate guide to recognizing, coping with, and overcoming chronic infection.Lyme Disease is a substantial problem. While the CDC reported 427,000 new cases in 2017 based on surveillance criteria, actual numbers based on clinical diagnosis put that number at over one million. It is now well accepted that 10 to 20 percent of these cases go on to become a chronic illness, and these numbers don't even include those people who became chronically ill without ever witnessing a tick attachment or a bulls-eye rash. In other words, hundreds of thousands of people develop a chronic illness every year. This is why Dr. Dan Kinderlehrer's book is so important and timely and has the potential to help millions who are victims of this epidemic. His integrative approach offers the most up-to-date and comprehensive plan available for treating and beating this disease. It will discuss brand new treatments such as disulfiram, which is being hailed as a major breakthrough, as well as the use of cannabis to treat pain and anxiety, among other developments in the field. With the staggering growth we are seeing in numbers of people afflicted, this book becomes more important every day. Kinderhlehrer is in a unique position to write this book. After completing a residency in Internal Medicine in 1979, he opened one of the first practices in the US in what was then called Holistic Medicine. After becoming an expert in nutrition and environmental illness, he became ill himself with Lyme disease complex. His long road to recovery has given him insights into what patients are going through; his background in internal medicine trained him to understand the complexities of his multi-systemic illness; his knowledge of environmental illness has enabled him to evaluate immune dysregulation; and his study of energetic medicine, spiritual alignment, and healing from trauma has yielded insights into how to help patients shift their belief systems to being well. Recovery from Lyme Disease is by far the most thorough book available on Lyme Disease Complex. It will provide patients with information that will guide them on their healing journeys, as well as supplying doctors with instruction on appropriate diagnosis and treatment approaches.

Lyme disease (Lyme borreliosis) is the most prevalent vector-borne illness in the United States and Europe and a growing threat to global health. In addition Lyme disease is considered a model system of emerging infectious diseases. The book Borrelia: Molecular Biology, Host Interaction and Pathogenesis published in 2010 was the first state-of-the-art reference work covering the myriad, interlaced facets of the enzootic disorders caused by pathogenic Borrelia. This current volume, by the same editors, builds on the previous work and contains a vast amount of new information, a wider scope, and increased coverage of genomics, genetics, evolutionary biology, vector biology, physiology, pathogenicity, immune response, and immune evasion. Written by renowned scientists who have made seminal contributions to the field, this book contains an expansive treatment of the options to track live spirochetes and evaluate gene expression in ticks and mice, provides insights into the workings of the flagellar motor, presents up-to-date research on the modulation of gene expression, and reviews recent studies on the Lyme disease spirochete's networks of regulatory pathways. The volume highlights and describes in detail the tremendous advances in understanding of the Borrelia genus at the molecular and cellular levels as well as the pathogenesis of Lyme disease and relapsing fever. This comprehensive volume is indispensable for anyone involved in Borrelia and Lyme disease research and is highly recommended for microbiologists, immunologists, and physicians with an interest in spirochetes, vector-borne illness, or emerging infectious diseases. The book is a recommended reference volume for all microbiology libraries.

The accepted message is that humankind has largely conquered infectious disease with a mixture of antibiotics and vaccines yet it is becoming clear that chronic hidden or latent infections (crypto-infections) lie behind many of today's big killers, including heart disease, dementia and cancer. From his experience as one of France's - and the world's - leading ID specialists, Dr Perrone examines the threats that both Lyme in particular and crypto-infections in general pose and how we can rise to the challenge.

Lyme disease: Global Status is one in a series of GIDEON ebooks which explore all individual infectious diseases, drugs, vaccines, outbreaks, surveys and pathogens in every country of the world. Data are based on the GIDEON web application (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing exhaustive search of the medical literature.The ebook includes: 1. Descriptive epidemiology 2. Clinical features 3. Distribution map 4. Images 5. Global status and status in every relevant country 6. References

While many doctors claim that Lyme disease—a tick-borne bacterial infection—is easily diagnosed and treated, other doctors and the patients they care for argue that it can persist beyond standard antibiotic treatment in the form of chronic Lyme disease. In Divided Bodies, Abigail A. Dumes offers an ethnographic exploration of the Lyme disease controversy that sheds light on the relationship between contested illness and evidence-based medicine in the United States. Drawing on fieldwork among Lyme patients, doctors, and scientists, Dumes formulates the notion of divided bodies: she argues that contested illnesses are disorders characterized by the division of bodies of thought in which the patient's experience is often in conflict with how it is perceived. Dumes also shows how evidence-based medicine has paradoxically amplified differences in practice and opinion by providing a platform of legitimacy on which interested parties—patients, doctors, scientists, politicians—can make claims to medical truth.

Lyme disease is one of the fastest growing vector-borne diseases in the world and urban residents in cities with regularly travelling populations should be considered high risk yet there is a little awareness of the issue among either patients or doctors. Based on years of diagnosing and treating this growing problem in NY City, Dr Raxlen, together with'expert patient'Allie Cashel and a team of international contributors, provides a road map for individuals who suspect they have been infected and are lost in the'medical maze'of Lyme and other tick-borne diseases, searching for a diagnosis and appropriate treatment. By highlighting the difficulties sufferers face, Raxlen et al aim to increase understanding of the Lyme epidemic worldwide and how sufferers can obtain reliable and effective diagnosis and treatment.

Lyme disease is not often discussed, which means the general public knows little about it. Many people are aware that it can be passed from ticks to humans, but questions remain. What are the symptoms? Is it contagious? Can it be treated? What are the best prevention methods? These questions and more are answered in this engaging book, with text that is enhanced with full-color photographs, annotated quotes, and informative sidebars. By fully informing themselves about this disease, readers will know the steps to take if they encounter it as well as how to support a loved one who contracts Lyme disease.

This new edition of Lyme Disease provides up-to-date evidence-based research and covers the significant advances in our understanding of the disorders referred to as Lyme disease or Lyme borreliosis. This book explores the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, the role of host immunity on pathogenesis and long term prognosis. The authors provide balanced perspectives on all aspects of Lyme disease and explicitly review both the basic biology of the infection and practical clinical aspects. This new edition: Includes new borrelial pathogens that have been identified (B. miyamotoi, B. mayonii and B. bavariensis among others). Provides updated information on the molecular biology of the organism, neuroborreliosis, and the role of the C6 peptide in diagnosis. Discusses the controversies about'chronic Lyme disease', post Lyme disease syndrome and other ongoing but non-specific symptoms that have been attributed to this infection. As the endemic footprint of Lyme disease continues to grow, this book provides a broad and detailed guide for clinicians and researchers involved with the diagnosis and treatment of the condition. Covering biology, epidemiology and therapeutics, it is also essential reading for students of global health and infectious disease.

Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online.In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade's advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.

'Superbly written and researched.'—Booklist'Builds a strong case.'—Kirkus Lyme disease is spreading rapidly around the globe as ticks move into places they could not survive before. The first epidemic to emerge in the era of climate change, the disease infects half a million people in the US and Europe each year, and untold multitudes in Canada, China, Russia, and Australia. Mary Beth Pfeiffer shows how we have contributed to this growing menace, and how modern medicine has underestimated its danger. She tells the heart-rending stories of families destroyed by a single tick bite, of children disabled, and of one woman's tragic choice after an exhaustive search for a cure. Pfeiffer also warns of the emergence of other tick-borne illnesses that make Lyme more difficult to treat and pose their own grave risks. Lyme is an impeccably researched account of an enigmatic disease, making a powerful case for action to fight ticks, heal patients, and recognize humanity's role in a modern scourge.