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In new CBME program, competency map has been provided by NMC for each subject. Competency map in the tabular format with reference to chapter and page number and citation of competency code inside the relevant places in text, have been provided in this new edition. Clinical application and applied aspects have been made more updated and revised. More numbers of ‘Clinical Notes'and ‘Important Notes'have been added to this edition, to make the student understand the physiological basis of clinical applications in medicine. New topics of Physiology of Stress, Physiology of Yoga and Meditation, Brain Death, Glucose Homeostasis and Pathophysiology of Diabetes and Body Fluid Volume Homeostasis, and Clinical Case Scenarios have been added to this edition. Physiology is a rapidly advancing subject. All major concepts and advances in physiology have been thoroughly incorporated in the text. The presentation of the texts, especially to explain key concepts have been made more structured with more point-wise (bulleted) description. Multiple choice questions (MCQs) that are part of all kinds of assessments have been thoroughly reviewed and new clinical-based and application-based MCQs have been added in this new edition.

Physiology is emerging as the central subject in medical science. With new revised curriculum of Medical Council of India (MCI), 2019, which has the recommendation for implementation of evidence-based, objective-oriented, clinically-focussed and skillbased integrated curriculum, physiology is the most suitable subject for such an evolutionary change in undergraduate medical profession in India. Physiology is the subject for complete integration with clinical and paraclinical subject, as Physiology provides the knowledge and basis of medical practice. In the new curriculum, Physiology as a subject will provide the link for integration among all the subjects. The present edition of the book is thoroughly revised in the light of new MCI 2019 guidelines for undergraduate medical curriculum. All major concepts and advances in physiology have been thoroughly incorporated in the text. The second edition of the book will fulfil the requirements and aspirations of all our readers.