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Your search keyword '"Tang, Huamin"' showing total 8 results
Start Over Author "Tang, Huamin" Publication Year Range Last 10 years Publisher american society for microbiology
8 results on '"Tang, Huamin"'

8. Human Herpesvirus 6A U14 Is Important for Virus Maturation.

Author

Mori J, Tang H, Kawabata A, Koike M, and Mori Y

Subjects
Cells, Cultured, Herpesvirus 6, Human genetics, Humans, Leukocytes, Mononuclear virology, Mutant Proteins genetics, Mutant Proteins metabolism, Viral Structural Proteins genetics, Herpesvirus 6, Human physiology, Viral Structural Proteins metabolism, Virus Replication
Abstract

Human herpesvirus 6A (HHV-6A) U14 is a virion protein with little known function in virus propagation. Here, we elucidated its function by constructing and analyzing U14-mutated viruses. We found that U14 is essential for HHV-6A propagation. We then constructed a mutant virus harboring dysfunctional U14. This virus showed severely reduced growth and retarded maturation. Taken together, these data indicate that U14 plays an important role during HHV-6A maturation., (Copyright © 2016, American Society for Microbiology. All Rights Reserved.)

Published
2015
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