1. Characteristics and clinical outcomes of adolescents infected by SARS-CoV-2: a systematic review.
- Author
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Gonçalves Campos, Cezenário, Aparecida Muniz, Luciene, Silva Belo, Vinícius, Cristina Costa, Cássia, de Souza Borges Neto, Juscelino, Rachid Novais, Rommel Larcher, Dutra Rabelo, Fernanda Lívia, Martins Júnior, Charles Henrique, Caetano Romano, Márcia Christina, and Alves Lamounier, Joel
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SARS-CoV-2 , *TREATMENT effectiveness , *TEENAGERS , *DIGITAL libraries , *RACE , *COUGH - Abstract
Objective: To verify the COVID-19 clinical characteristics, associated comorbidities, and outcomes in adolescents. Data source: This is a systematic review study based on articles published between 2020 and 2022 in the United States National Library of Medicine - PubMed (MedLine), Virtual Health Library – VHL (LILACS), Science Direct, Web of Science, and Scopus (Elsevier) databases. The study was registered in the International Prospective Register of Systematic Reviews, under No. CRD42022309108. Data synthesis: A total of 1188 studies were identified. After applying the selection criteria, 13 articles were included. Prevalence was 25%; mild cases were predominant; and fever, cough, headache, anosmia, nasal congestion, and ageusia were frequent. Fever and cough were proportionally higher in hospitalized cases: 81 and 68%, respectively. Dyspnea (odds ratio [OR] 6.3; confidence interval 95%[CI] 2.8–14.3), fever (OR 3.8; 95%CI 2.0–7.4), and cough (OR 3.4; 95%CI 2.0–6.0) were associated with severe cases. Up to 28% required intensive care and 38% required mechanical ventilation. Pre-existing comorbidities increased the risk of hospitalization and death. Severe cases were associated with the risk of death (relative risk [RR] 4.6; 95%CI 2.8–7.5). The black, mixed, and indigenous races/skin colors represented risk groups, as well as residents of poorer regions. Conclusions: The review provided a better understanding of the disease profile and may favor the development of public policies, in addition to contributing to the current literature in the field of adolescent health. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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