288 results
Search Results
2. People with blood disorders can be more vulnerable during COVID-19 pandemic: A hypothesis paper.
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Aydemir, Duygu and Ulusu, Nuriye Nuray
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COVID-19 pandemic , *COVID-19 , *NON-communicable diseases , *IRON metabolism , *VIRAL transmission , *BIOCHEMISTRY - Abstract
The world has been encountered with COVID-19 pandemic since at the beginning of 2020 and the number of infected people by COVID-19 is increasing every day. Despite various studies conducted by researchers and doctors, no treatment has been developed until now, therefore self-protection and isolation are strongly recommended to stop the spread of the virus. The elderly population and people with chronic diseases such as hypertension, cardiovascular diseases, diabetes, and cancer are categorized as risk groups, however, we suggest that people with hemoglobinopathies or porphyria can be described as risk groups as well. Current in silico studies have revealed that the COVID-19 virus can attack heme and hemoglobin metabolisms which are responsible for the oxygen transport to the tissues, iron metabolism, elevated levels of oxidative stress, and tissue damage. Data of the in silico study have been supported with the biochemistry and hemogram results of the COVID-19 patients, for instance hemoglobin levels decreased and serum ferritin and C-reactive protein levels increased. Indicated biochemistry biomarkers are tightly associated with inflammation, iron overload, and oxidative stress. In conclusion, since people with hemoglobinopathies or porphyria have already impaired heme and hemoglobin metabolism, COVID-19 infection can enhance the adverse effects of impaired hemoglobin metabolism and accelerate the progression of severe symptoms in patients with hemoglobinopathies or porphyria compared to the normal individuals. Thus those people can be considered as a risk group and extra precautions should be applied for them to protect them. [ABSTRACT FROM AUTHOR]
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- 2021
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3. Measuring COVID-19 related anxiety and obsession: Validation of the Coronavirus Anxiety Scale and the Obsession with COVID-19 Scale in a probability Chinese sample
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Kwok Kit Tong, Anise M. S. Wu, Xiaoyu Su, Juliet Honglei Chen, and Eilo Wing-yat Yu
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Predictive validity ,Adult ,Male ,China ,Concurrent validity ,Anxiety ,Assessment ,Obsession ,Mental distress ,medicine ,Humans ,Measurement invariance ,Pandemics ,Language ,Probability ,Pandemic ,Depression ,SARS-CoV-2 ,Reproducibility of Results ,COVID-19 ,Mental health ,Coronavirus ,Psychiatry and Mental health ,Clinical Psychology ,Distress ,Cross-Sectional Studies ,Scale (social sciences) ,Female ,medicine.symptom ,Obsessive Behavior ,Psychology ,Clinical psychology ,Research Paper - Abstract
Background With concern over the rise in mental health symptoms associated with the COVID-19 pandemic, the present study set out to address the absence of pandemic-specific screening tools for detecting those in Chinese societies who are at-risk for experiencing mental distress due to the pandemic; thus, its aim was to validate the Coronavirus Anxiety Scale (CAS) and Obsession with COVID-19 Scale (OCS) in Chinese adults. Methods With a two-stage cluster random sampling method, we surveyed 1011 Chinese community-dwelling adults (38.8% men; 41.2 years old on average with an SD of 15.8) in June and July of 2020. Results Our psychometric evaluation results showed that the Chinese version of CAS and OCS retained their original one-dimensional structure and demonstrated measurement invariance across genders. In line with validation studies of the CAS and OCS in other languages, subsequent analyses also provided support to our Chinese version with respect to their satisfactory internal consistency (α = .87 and .73, respectively), and good concurrent validity (i.e., positive associations with negative feelings, excessive time-consumption, subjective distress, and functioning impairment). Limitations Due to constraints of time and cross-sectional design, we only validated CAS and OCS among Chinese adults and did not evaluate their test-retest reliability nor predictive validity. Conclusions Considering the practical benefits of understanding the source of mental symptoms during the pandemic, we recommend the use of CAS and OCS in Chinese communities to facilitate early identification and intervention for those who require clinical attention due to their COVID-19 related anxiety and obsessive thoughts.
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- 2021
4. Social Isolation and Anxiety Disorder During the COVID-19 Pandemic and Lockdown in China
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Flavio F. Marsiglia, Shiyou Wu, Mengni Yao, Wenjie Duan, and Chunxia Deng
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China ,Psychological intervention ,Interpersonal communication ,medicine ,Humans ,Social isolation ,Location ,Child ,Pandemics ,Pandemic ,SARS-CoV-2 ,COVID-19 ,medicine.disease ,Mental health ,Anxiety Disorders ,Psychiatry and Mental health ,Clinical Psychology ,Propensity score matching ,Quarantine ,Communicable Disease Control ,Anxiety ,medicine.symptom ,Psychology ,Anxiety disorder ,Clinical psychology ,Research Paper - Abstract
The COVID-19 pandemic and lockdown measures have had a profound impact on the emotions, anxiety, and mental health of affected communities. Despite this, there is a lack of knowledge about the possible generational and geographical differences in the effects on the mental health of individuals. This study examines the impact of COVID-19 related quarantine on symptoms of generalized anxiety disorders (GAD) among parents and children (N = 4503). It also compares the outcomes of residents from the initial COVID-19 epicenter of Wuhan to those in surrounding areas. Subgroup analyses were conducted by child and parent samples, and by Wuhan city and other cities in the Hubei province. Propensity score radius matching and ordinary least squares regressions were used to examine the relationship between quarantine and GAD symptoms. Results showed that quarantine had more psychological impact on parents than children, regardless of geographic location. Parents that experienced quarantine in Wuhan city, reported a significantly higher level of symptoms of GAD than those that did not. Parents from other cities showed no such difference. For both children and parents, interpersonal communication about COVID-19 and social media exposure to pandemic-related information were linked to GAD symptoms. Targeted policies and interventions are needed to address the psychological impacts of COVID-19 lockdown.
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- 2021
5. Coping strategies, cyberbullying behaviors, and depression among Chinese netizens during the COVID-19 pandemic: a web-based nationwide survey
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Fan Yang
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Adult ,Male ,Coping (psychology) ,China ,Adolescent ,Cross-sectional study ,Psychological intervention ,Cyberbullying ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Surveys and Questionnaires ,Pandemic ,Adaptation, Psychological ,Humans ,Young adult ,Pandemics ,Aged ,Coping strategies ,Aged, 80 and over ,Governance ,Internet ,Depression ,Social distance ,Stressor ,Questionnaire ,COVID-19 ,Middle Aged ,030227 psychiatry ,Psychiatry and Mental health ,Clinical Psychology ,Stigma ,Cross-Sectional Studies ,Female ,Psychology ,030217 neurology & neurosurgery ,Clinical psychology ,Research Paper - Abstract
Highlights • A two-factor structure applied to participants’ coping strategies, namely problem-focused coping and emotion-focused coping, and the former was more adopted. • Problem-focused coping was associated with less cyberbullying behaviors while had no correlation with depression. • Emotion-focused coping was found positively correlated with cyberbullying and depression. • The association between emotion-focused coping and depression was mediated by cyberbullying., Background: As a major life stressor now, the COVID-19 pandemic could substantially increase risks of cyberbullying and depression for global people, especially in the context of increased digital interconnectedness and strict social distancing. Though people are adopting different coping strategies, still little is known about their cyberbullying and depression and how the two associated with coping strategies. Methods: A web-based nationwide questionnaire survey was conducted among 5,608 netizens during the peak time of COVID-19 in China. The study collected cross-sectional data on participants’ coping strategies, general cyberbullying behaviors, cyberbullying behaviors specifically to residents of Hubei Province where first COVID-19 case was reported, and depression. Results: A two-factor structure applied to participants’ coping strategies, namely problem-focused coping and emotion-focused coping, and the former was more adopted. There existed gender, age, education, and income differences in the coping strategies. Problem-focused coping was associated with less cyberbullying behaviors while had no correlation with depression; emotion-focused coping was found positively correlated with cyberbullying and depression. The association between emotion-focused coping and depression was mediated by cyberbullying. Limitations: The study used cross-sectional design, and its findings should be cautioned to be generalized to other countries, due to the differences in culture, stage of crisis, and government policies on COVID-19. Conclusions: Problem-focused coping was associated with less cyberbullying, and emotion-focused coping predicted cyberbullying and depression. Cyberbullying mediated the correlation between emotion-focused coping and depression. These findings provide new perspectives for interventions on people's coping strategies towards COVID-19 pandemic.
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- 2020
6. Changing trends in psychiatric emergency service admissions during the COVID-19 outbreak: Report from a worldwide epicentre
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Eduard Vieta, Gerard Anmella, Marta Gómez-Ramiro, Maria Sagué-Vilavella, Giovanna Fico, Andrea Murru, Isabella Pacchiarotti, Marina Garriga, Diego Hidalgo-Mazzei, Eduard Parellada, and Mireia Vázquez
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medicine.medical_specialty ,Admission ,03 medical and health sciences ,Social support ,symbols.namesake ,0302 clinical medicine ,Humans ,Medicine ,Poisson regression ,Psychiatry ,Pandemics ,Retrospective Studies ,Emergency Services, Psychiatric ,Pandemic ,SARS-CoV-2 ,business.industry ,Emergency psychiatry ,Public health ,Telepsychiatry ,COVID-19 ,Retrospective cohort study ,Mental health ,030227 psychiatry ,Hospitalization ,Psychiatry and Mental health ,Clinical Psychology ,Spain ,Communicable Disease Control ,Quarantine ,symbols ,Anxiety ,medicine.symptom ,Emergency Service, Hospital ,business ,030217 neurology & neurosurgery ,Research Paper - Abstract
Highlights • A retrospective analysis was performed of all patients admitted to the Psychiatric Emergency Service 90 days before and after March 14th, 2020, the first day of lockdown in Spain due to COVID-19. • During the lockdown the number of admissions decreased by 37.9% while a significant increase in the percentage of patients requiring acute psychiatric hospitalization was observed. • Anxiety spectrum disorders accumulated the greatest decrease in admission rates compared to the three months before lockdown. • A statistically significant increase in admissions rates was found in patients with dementia-like cognitive impairments, autism spectrum, and substance use disorders during the lockdown., Background During the COVID-19 pandemic, a structural reorganization was imposed on public health systems. Psychiatry services were also affected with the imposed reduction of non-urgent consultations. We aim to explore the effect of these changes on a Psychiatry Emergency Service during COVID-19 lockdown in Spain. Methods A retrospective analysis was performed on all patients admitted to our Psychiatric Emergency Service 90 days before and after March 14th, 2020, the first day of lockdown in Spain. Extracted data were compared between the two periods. Poisson regression analysis was performed to analyze changes in admission rates. Results 1,958 psychiatric emergency admissions were analyzed. Although the number of admissions decreased by 37.9%, we observed a significant increase in the percentage of acute psychiatric hospitalization during the lockdown. Anxiety spectrum disorders accumulated the greatest significant decrease in admission rates during the lockdown. On the other hand, a significant increase in admissions rates was found in patients with dementia, autism spectrum disorders, and substance use disorders during the lockdown. Limitations This study was conducted in a single psychiatric emergency service, preventing a generalization of our results. The comparison time period might have biased our results due to the influence of external factors. Conclusion Mental health consequences of COVID-19 are becoming apparent. A reduction of admission rates for anxiety disorders might be related telepsychiatry implementation during the lockdown. Other conditions particularly vulnerable to the routine changes and lack of social support have suffered the most, and efforts should be placed to treat these situations.
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- 2020
7. Depressed, anxious, and stressed: What have healthcare workers on the frontlines in Egypt and Saudi Arabia experienced during the COVID-19 pandemic?
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Ashraf A. Ewis, Zeinab Mohammed, Ahmed Arafa, Momen Elshazley, and Omaima Mahmoud
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Male ,Cross-sectional study ,health care facilities, manpower, and services ,Anxiety ,0302 clinical medicine ,Pandemic ,Health care ,Young adult ,Depression (differential diagnoses) ,Middle East ,Depression ,Age Factors ,virus diseases ,Middle Aged ,Anxiety Disorders ,humanities ,Psychiatry and Mental health ,Clinical Psychology ,Sleeping hours ,Egypt ,Female ,medicine.symptom ,geographic locations ,Research Paper ,Adult ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Adolescent ,Health Personnel ,education ,Saudi Arabia ,Stress ,03 medical and health sciences ,Young Adult ,Sex Factors ,parasitic diseases ,medicine ,Healthcare workers ,Humans ,Pandemics ,Depressive Disorder ,business.industry ,COVID-19 ,030227 psychiatry ,Cross-Sectional Studies ,Family medicine ,business ,030217 neurology & neurosurgery ,Stress, Psychological - Abstract
Highlights • HCWs in Egypt and Saudi-Arabia experienced depression, anxiety, and stress during the COVID-19 pandemic. • Female sex, age ≤30 years, attending night shifts, and watching/reading COVID-19 news associated with worse psychological disturbances. • Providing psychological support to HCWs during the COVID-19 pandemic is an urgent need., Introduction As the Novel Corona Virus Disease (COVID-19) was declared by the world health organization a pandemic in March 2020, thousands of healthcare workers (HCWs) worldwide were on the frontlines fighting against the pandemic. Herein, we selected two Middle East countries; Egypt and Saudi Arabia to investigate the psychological impacts of the COVID-19 pandemic on their HCWs. Methods In this cross-sectional study, a Google survey was used to access HCWs in many hospitals in Egypt and Saudi Arabia between the 14th and 24th of April 2020. The survey assessed HCWs regarding their sociodemographic and occupational features, sleeping hours, and psychological impacts of the COVID-19 pandemic using the Depression Anxiety Stress Scale-21 (DASS-21). Results This study included 426 HCWs (48.4% physicians, 24.2% nurses, and 27.4% other HCWs). Of them, 69% had depression, 58.9% had anxiety, 55.9% had stress, and 37.3% had inadequate sleeping (
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- 2020
8. Alcohol use and mental health status during the first months of COVID-19 pandemic in Australia
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Maggie Kirkman, Jane Fisher, Thach Duc Tran, Karin Hammarberg, and Hau Thi Minh Nguyen
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Male ,Health Status ,Alcohol ,Patient Health Questionnaire ,Anxiety ,Social group ,chemistry.chemical_compound ,0302 clinical medicine ,Surveys and Questionnaires ,Pandemic ,Prevalence ,Depression (differential diagnoses) ,education.field_of_study ,Depression ,Age Factors ,Middle Aged ,Psychiatry and Mental health ,Clinical Psychology ,Mental Health ,Female ,medicine.symptom ,Coronavirus Infections ,Alcohol use ,Research Paper ,Adult ,medicine.medical_specialty ,Adolescent ,Alcohol Drinking ,Pneumonia, Viral ,Population ,Betacoronavirus ,Young Adult ,03 medical and health sciences ,Sex Factors ,medicine ,Humans ,Psychiatry ,education ,Pandemics ,Aged ,SARS-CoV-2 ,business.industry ,Australia ,COVID-19 ,Mental health ,030227 psychiatry ,Cross-Sectional Studies ,chemistry ,Self Report ,business ,030217 neurology & neurosurgery - Abstract
Background We aimed to estimate the population prevalence of people with changes in their usual patterns of alcohol use during the early stages of the novel coronavirus pandemic of 2020 (COVID-19) pandemic in Australia; assess the association between mental health status and changes in alcohol use during the pandemic; and examine if the associations were modified by gender and age. Methods This study was an anonymously-completed online self-report survey. Changes in alcohol use were assessed using a single fixed-choice study-specific question. Mental health was assessed using the Patient Health Questionnaire 9 and the Generalized Anxiety Disorder Scale. Results A total of 13,829 people contributed complete data and were included in the analysis. Overall, about one in five adults reported that they had been drinking more alcohol since the COVID-19 pandemic began than they used to. People were more likely to be drinking alcohol more than they used to if they had more severe symptoms of depression or anxiety. The associations between depressive and anxiety symptoms and increased alcohol use since the COVID-19 pandemic began were consistent between females and males. Limitations Online surveys are less accessible to some groups of people. The data are self-report and not diagnostic. Cross-sectional data can identify associations, not causal relationships. The study was limited to participants from Australia. Conclusions These data indicate that there is a need for public policies focused on alcohol use during the COVID-19 pandemic and the strategies should include specific consideration of the needs of people with mental health problems.
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- 2020
9. Anxiety and depression symptoms of medical staff under COVID-19 epidemic in China
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Nan Zhang, Xing Wang, Bo Hu, Yuan Liu, Yuling Zhang, Hongguang Chen, Qinyi Fan, Liping Huang, and Mengqian Li
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Adult ,Male ,medicine.medical_specialty ,China ,Generalized anxiety disorder ,Psychological intervention ,Survey sampling ,Medical staff ,Patient Health Questionnaire ,Anxiety ,Logistic regression ,Stress ,03 medical and health sciences ,0302 clinical medicine ,Pandemic ,medicine ,Prevalence ,Humans ,Psychiatry ,Pandemics ,Depression (differential diagnoses) ,Depressive Disorder ,business.industry ,Depression ,COVID-19 ,medicine.disease ,Mental health ,Anxiety Disorders ,030227 psychiatry ,Psychiatry and Mental health ,Clinical Psychology ,Cross-Sectional Studies ,Correlators ,Female ,medicine.symptom ,business ,030217 neurology & neurosurgery ,Research Paper - Abstract
Highlights • The estimated self-reported rates of anxiety symptoms and depression symptoms among medical staff were 13.3% and 18.4% respectively under COVID-19 epidemic. • Up to 23.9% investigated medical staff reported having anxiety or depression symptoms. • Psychological interventions for medical staff should be integrated into the strategies for fighting COVID-19., Background It is well known that unexpected pandemic has led to an increase in mental health problems among a variety of populations. Methods In this study, an online non-probability sample survey was used to anonymously investigate the anxiety and depression symptoms among medical staff under the COVID-19 outbreak. The questionnaire included Perceived Stress Scale-10 (PSS-10), Generalized Anxiety Disorder 7-Item Scale (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). Factors associated with anxiety and depression symptoms were estimated by logistic regression analysis. Results A total of 1090 medical staff were investigated in this study. The estimated self-reported rates of anxiety symptoms, depression symptoms and both of the two were 13.3%, 18.4% and 23.9% respectively. Factors associated with self-reported anxiety symptoms include married status (OR=2.3, 95%CI: 1.2, 4.4), not living alone (OR=0.4, 95%CI: 0.2, 0.7), never confiding their troubles to others (OR=2.2, 95%CI: 1.4, 3.5) and higher stress (OR=14.4, 95%CI: 7.8, 26.4). Factors associated with self-reported depression symptoms include not living alone (OR=0.4, 95%CI: 0.3, 0.7), sometimes/often getting care from neighbours (OR=0.6, 95%CI: 0.4, 0.9), never confiding their troubles to others (OR=2.0, 95%CI: 1.3, 3.0) and higher stress (OR=9.7, 95%CI: 6.2, 15.2). Limitations The study was a non-probability sample survey. Besides, scales used in this study can only identify mental health states. Conclusions Under outbreak of COVID-19, self-reported rates of anxiety symptoms and depression symptoms were high in investigated medical staff. Psychological interventions for those at high risk with common mental problems should be integrated into the work plan to fight against the epidemic.
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- 2020
10. Psychological impact of COVID-19 pandemic in the Philippines
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Patrick Wincy C Reyes, Michael L. Tee, Katrina Joy G. Aligam, Cherica A. Tee, Roger C.M. Ho, Joseph P. Anlacan, and Vipat Kuruchittham
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Male ,Philippines ,Health Status ,Disease ,Anxiety ,0302 clinical medicine ,Surveys and Questionnaires ,Pandemic ,Prevalence ,Single person ,Young adult ,Child ,Psychological impact ,Depression (differential diagnoses) ,media_common ,Depression ,Age Factors ,Single Person ,Middle Aged ,Psychiatry and Mental health ,Clinical Psychology ,Mental Health ,Female ,medicine.symptom ,Worry ,Coronavirus Infections ,Clinical psychology ,Research Paper ,Adult ,Adolescent ,media_common.quotation_subject ,Health Personnel ,Pneumonia, Viral ,Stress ,03 medical and health sciences ,Betacoronavirus ,Young Adult ,Sex Factors ,medicine ,Humans ,Students ,Pandemics ,business.industry ,SARS-CoV-2 ,COVID-19 ,Mental health ,030227 psychiatry ,business ,030217 neurology & neurosurgery ,Stress, Psychological - Abstract
Highlights • Students report moderate-to-severe psychological impact of the COVID-19 pandemic. • Timely and adequate health information has protective psychological effect. • Health care workers are less likely to be psychologically affected. • Home quarantine is associated with depression, anxiety and stress symptoms., Background The 2019 coronavirus disease (COVID-19) pandemic poses a threat to societies’ mental health. This study examined the prevalence of psychiatric symptoms and identified the factors contributing to psychological impact in the Philippines. Methods A total of 1879 completed online surveys were gathered from March 28-April 12, 2020. Collected data included socio-demographics, health status, contact history, COVID-19 knowledge and concerns, precautionary measures, information needs, the Depression, Anxiety and Stress Scales (DASS-21) and the Impact of Events Scale-Revised (IES-R) ratings. Results The IES-R mean score was 19.57 (SD=13.12) while the DASS-21 mean score was 25.94 (SD=20.59). In total, 16.3% of respondents rated the psychological impact of the outbreak as moderate-to-severe; 16.9% reported moderate-to-severe depressive symptoms; 28.8% had moderate-to-severe anxiety levels; and 13.4% had moderate-to-severe stress levels. Female gender; youth age; single status; students; specific symptoms; recent imposed quarantine; prolonged home-stay; and reports of poor health status, unnecessary worry, concerns for family members, and discrimination were significantly associated with greater psychological impact of the pandemic and higher levels of stress, anxiety and depression (p
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- 2020
11. Do social isolation and neighborhood walkability influence relationships between COVID-19 experiences and wellbeing in predominantly Black urban areas?
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Madhumita Ghosh-Dastidar, Wendy M. Troxel, Robin L. Beckman, Rebecca L. Collins, Melissa L. Finucane, and Tamara Dubowitz
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medicine.medical_specialty ,Social isolation ,Ecology ,Public health ,COVID-19 ,Walkability ,Management, Monitoring, Policy and Law ,Moderation ,Mental health ,Urban Studies ,Risk perception ,Residential segregation in the United States ,Black ,Environmental health ,Pandemic ,medicine ,medicine.symptom ,Psychology ,Urban health ,Nature and Landscape Conservation ,Research Paper - Abstract
Black Americans have been disproportionately affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19) pandemic. Since the pandemic's start, we have observed compounded health, social, and economic impacts for communities of color, fueled in part by profound residential segregation in the United States that, for centuries prior to the pandemic, created differences in access to opportunity and resources. Based on a longitudinal cohort of Black residents living in two racially isolated Pittsburgh neighborhoods, we sought to: 1) describe the experiences of behavioral responses to COVID-19 conditions (e.g., closures of businesses, schools, government offices) and illness experiences reported by residents within these disinvested, urban areas and 2) determine if these experiences were associated with perceptions of risk, negative mental health outcomes, and food insecurity; and 3) examine whether any of the associations were explained by social isolation or modified by neighborhood walkability. We found direct associations between residents' experience with COVID-19-related closures and with the illness, with perceived risk, and change in psychological distress, sleep quality, and food insecurity from pre-COVID-19 levels. Social isolation was a statistically significant mediator of all of these associations, most strongly mediating the pathway to psychological distress. We found neighborhood walkability to be a significant moderator of the association between closure experiences and sleep quality. The results suggest that experiences of COVID-19 closures and illness were associated with serious threats to public health in Black, disinvested, urban neighborhoods, beyond those caused directly by the virus. Outcomes of the pandemic appear very much dependent on the extent to which social and physical resources are available to meet the demands of stress.
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- 2021
12. The success rate of online illicit drug transactions during a global pandemic
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Luca Giommoni, David Décary-Hétu, Marie-Pier Villeneuve-Dubuc, and Andréanne Bergeron
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Good faith ,Coronavirus disease 2019 (COVID-19) ,Vendor ,media_common.quotation_subject ,Internet privacy ,Medicine (miscellaneous) ,Sample (statistics) ,Pandemic ,Illicit drug ,Humans ,Drug Trafficking ,Market disruption ,Pandemics ,Cryptomarket ,media_common ,Illicit drug market ,business.industry ,Illicit Drugs ,SARS-CoV-2 ,Health Policy ,Addiction ,Commerce ,COVID-19 ,Darkweb ,Abusive behaviour ,business ,Research Paper - Abstract
Background and Aims In the months following the onset of the COVID-19 pandemic, the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA; 2020) observed an increased use of cryptomarkets, which led them to question whether cryptomarkets constituted a more convenient channel via which to distribute illicit drugs without any in-person contact. However, as more countries' borders closed, the likelihood is that cryptomarkets have been negatively impacted. We aim to measure and understand the success rate of transactions on cryptomarkets during the ongoing COVID-19 pandemic, through recourse to self-reported data that documents the outcome of cryptomarket transactions. Methods To collect self-reported data on cryptomarket transactions, we launched a platform where participants can enter information about their prior activities on cryptomarkets. The sample consists of 591 valid self-reports that were received between January 1st, 2020 and August 21st, 2020. Results The number of unsuccessful transactions increased concurrently with the global spread of the pandemic. Both the international and inter-continental nature of the transactions and the severity of the crisis in the vendor's country are significantly associated with delivery failure. Conclusions Drug cryptomarkets may have been disrupted due to the pandemic. The results lead to two opposing explanations for unsuccessful transactions. One explanation for the lower success rate is the inability of drug dealers to deliver on past promises that were made in good faith, while the second points towards opportunistic and abusive behaviour by drug dealers.
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- 2021
13. SARS-CoV-2 genomic surveillance in Costa Rica: Evidence of a divergent population and an increased detection of a spike T1117I mutation
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Claudio Soto-Garita, Melany Calderón-Osorno, Eugenia Corrales-Aguilar, Hebleen Brenes, Jan Felix Drexler, Adriana Godínez, Estela Cordero-Laurent, Coingesa-Cr Consorcio Interinstitucional de Estudios Genómicos del SARS-CoV Costa Rica, Francisco Duarte-Martínez, Jose Arturo Molina-Mora, Andres Moreira-Soto, and Cristian Pérez-Corrales
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0301 basic medicine ,Microbiology (medical) ,Costa Rica ,Male ,Models, Molecular ,Protein Conformation ,030106 microbiology ,Population ,Genomics ,Biology ,medicine.disease_cause ,Microbiology ,Genome ,DNA sequencing ,Virus ,03 medical and health sciences ,Genomic surveillance ,Pandemic ,Genetic variation ,Genetics ,medicine ,Humans ,COSTA RICA ,education ,Molecular Biology ,Ecology, Evolution, Behavior and Systematics ,Phylogeny ,education.field_of_study ,Mutation ,SARS-CoV-2 ,COVID-19 ,Genetic Variation ,030104 developmental biology ,Infectious Diseases ,Population Surveillance ,Spike Glycoprotein, Coronavirus ,Female ,Research Paper - Abstract
Genome sequencing is a key strategy in the surveillance of SARS-CoV-2, the virus responsible for the COVID-19 pandemic. Latin America is the hardest-hit region of the world, accumulating almost 20% of COVID-19 cases worldwide. In Costa Rica, from the first detected case on March 6th to December 31st almost 170,000 cases have been reported. We analyzed the genomic variability during the SARS-CoV-2 pandemic in Costa Rica using 185 sequences, 52 from the first months of the pandemic, and 133 from the current wave. Three GISAID clades (G, GH, and GR) and three PANGOLIN lineages (B.1, B.1.1, and B.1.291) were predominant, suggesting multiple re-introductions from other regions. The whole-genome variant calling analysis identified a total of 283 distinct nucleotide variants, following a power-law distribution with 190 single nucleotide mutations in a single sequence, and only 16 mutations were found in >5% sequences. These mutations were distributed through the whole genome. The prevalence of worldwide-found variant D614G in the Spike (98.9% in Costa Rica), ORF8 L84S (1.1%) is similar to what is found elsewhere. Interestingly, the frequency of mutation T1117I in the Spike has increased during the current pandemic wave beginning in May 2020 in Costa Rica, reaching 29.2% detection in the full genome analyses in November 2020. This variant has been observed in less than 1% of the GISAID reported sequences worldwide in 2020. Structural modeling of the Spike protein with the T1117I mutation suggests a potential effect on the viral oligomerization needed for cell infection, but no differences with other genomes on transmissibility, severity nor vaccine effectiveness are predicted. In conclusion, genome analyses of the SARS-CoV-2 sequences over the course of the COVID-19 pandemic in Costa Rica suggest the introduction of lineages from other countries and the detection of mutations in line with other studies, but pointing out the local increase in the detection of Spike-T1117I variant. The genomic features of this virus need to be monitored and studied in further analyses as part of the surveillance program during the pandemic., Graphical abstract Unlabelled Image
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- 2021
14. Methodology for modelling the new COVID-19 pandemic spread and implementation to European countries
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Stavros Maltezos
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0301 basic medicine ,Microbiology (medical) ,Physics - Physics and Society ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Gross Domestic Product ,030106 microbiology ,Large population ,FOS: Physical sciences ,Epidemic ,Physics and Society (physics.soc-ph) ,Biology ,Microbiology ,03 medical and health sciences ,Pandemic ,Genetics ,Econometrics ,Humans ,Computer Simulation ,Quantitative Biology - Populations and Evolution ,Molecular Biology ,Ecology, Evolution, Behavior and Systematics ,Population Density ,Models, Statistical ,SARS-CoV-2 ,Populations and Evolution (q-bio.PE) ,Outbreak ,COVID-19 ,Semi-Gaussian ,Pathogenicity ,Europe ,030104 developmental biology ,Infectious Diseases ,FOS: Biological sciences ,SIR ,Parametrization ,Research Paper ,Forecasting - Abstract
After the breakout of the disease caused by the new virus COVID-19, the mitigation stage has been reached in most of the countries in the world. During this stage, a more accurate data analysis of the daily reported cases and other parameters became possible for the European countries and has been performed in this work. Based on a proposed parametrization model appropriate for implementation to an epidemic in a large population, we focused on the disease spread and we studied the obtained curves, as well as, we investigated probable correlations between the country's characteristics and the parameters of the parametrization. We have also developed a methodology for coupling our model to the SIR-based models determining the basic and the effective reproductive number referring to the parameter space. The obtained results and conclusions could be useful in the case of a recurrence of this repulsive disease in the future., 8 pages, 6 figures and 2 tables
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- 2021
15. A fractional-order compartmental model for the spread of the COVID-19 pandemic
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Abdul Q. M. Khaliq and T. A. Biala
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Numerical Analysis ,Empirical data ,education.field_of_study ,Coronavirus disease 2019 (COVID-19) ,Applied Mathematics ,Population ,Parameter estimation and identifiability ,COVID-19 ,01 natural sciences ,SEIR model ,Time-fractional model ,010305 fluids & plasmas ,Order (exchange) ,Modeling and Simulation ,0103 physical sciences ,Pandemic ,Statistics ,Identifiability ,010306 general physics ,education ,Sensitivity analysis ,Basic reproduction number ,Contact tracing ,Mathematics ,Research Paper - Abstract
We propose a time-fractional compartmental model (SEI A I S HRD) comprising of the susceptible, exposed, infected (asymptomatic and symptomatic), hospitalized, recovered and dead population for the COVID-19 pandemic. We study the properties and dynamics of the proposed model. The conditions under which the disease-free and endemic equilibrium points are asymptotically stable are discussed. Furthermore, we study the sensitivity of the parameters and use the data from Tennessee state (as a case study) to discuss identifiability of the parameters of the model. The non-negative parameters in the model are obtained by solving inverse problems with empirical data from California, Florida, Georgia, Maryland, Tennessee, Texas, Washington and Wisconsin. The basic reproduction number is seen to be slightly above the critical value of one suggesting that stricter measures such as the use of face-masks, social distancing, contact tracing, and even longer stay-at-home orders need to be enforced in order to mitigate the spread of the virus. As stay-at-home orders are rescinded in some of these states, we see that the number of cases began to increase almost immediately and may continue to rise until the end of the year 2020 unless stricter measures are taken.
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- 2021
16. Topological Analysis for Sequence Variability: Case Study on more than 2K SARS-CoV-2 sequences of COVID-19 infected 54 countries in comparison with SARS-CoV-1 and MERS-CoV
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Indrajit Saha, Jnanendra Prasad Sarkar, Debasree Maity, Ujjwal Maulik, and Arijit Seal
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0301 basic medicine ,viruses ,medicine.disease_cause ,Severe Acute Respiratory Syndrome ,MERS-CoV ,Pandemic ,Global health ,Coronavirus ,Genomic sequences ,education.field_of_study ,Coronavirsus ,virus diseases ,Europe ,Infectious Diseases ,Severe acute respiratory syndrome-related coronavirus ,Host-Pathogen Interactions ,Middle East Respiratory Syndrome Coronavirus ,Coronavirus Infections ,Research Paper ,Microbiology (medical) ,Asia ,030106 microbiology ,Population ,Sequence alignment free technique ,Context (language use) ,Sequence alignment ,Genome, Viral ,Biology ,Topology ,Microbiology ,Virus ,03 medical and health sciences ,medicine ,Genetics ,Humans ,education ,Molecular Biology ,Pandemics ,Ecology, Evolution, Behavior and Systematics ,Sequence (medicine) ,Base Sequence ,SARS-CoV-2 ,fungi ,Australia ,COVID-19 ,Computational Biology ,Genetic Variation ,respiratory tract diseases ,030104 developmental biology ,Africa ,Americas ,Sequence Alignment - Abstract
The pandemic due to novel coronavirus, SARS-CoV-2 is a serious global concern now. More than thousand new COVID-19 infections are getting reported daily for this virus across the globe. Thus, the medical research communities are trying to find the remedy to restrict the spreading of this virus, while the vaccine development work is still under research in parallel. In such critical situation, not only the medical research community, but also the scientists in different fields like microbiology, pharmacy, bioinformatics and data science are also sharing effort to accelerate the process of vaccine development, virus prediction, forecasting the transmissible probability and reproduction cases of virus for social awareness. With the similar context, in this article, we have studied sequence variability of the virus primarily focusing on three aspects: (a) sequence variability among SARS-CoV-1, MERS-CoV and SARS-CoV-2 in human host, which are in the same coronavirus family, (b) sequence variability of SARS-CoV-2 in human host for 54 different countries and (c) sequence variability between coronavirus family and country specific SARS-CoV-2 sequences in human host. For this purpose, as a case study, we have performed topological analysis of 2391 global genomic sequences of SARS-CoV-2 in association with SARS-CoV-1 and MERS-CoV using an integrated semi-alignment based computational technique. The results of the semi-alignment based technique are experimentally and statistically found similar to alignment based technique and computationally faster. Moreover, the outcome of this analysis can help to identify the nations with homogeneous SARS-CoV-2 sequences, so that same vaccine can be applied to their heterogeneous human population., Highlights • Topological analysis of more than 2K SARS-CoV-2 Sequences • Sequence variability among SARS-CoV-1, MERS-CoV and SARS-CoV-2 • Sequence variability of SARS-CoV-2 in 54 countries • Development of Semi-Alignment based technique • Sequence similarity can help in decision making to apply vaccine
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- 2021
17. Protected areas as a space for pandemic disease adaptation: A case of COVID-19 in Hong Kong
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Lewis T.O. Cheung, Anson T.H. Ma, Theresa Wing Ling Lam, and Lincoln Fok
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SARS ,Ecology ,Resilience ,Social distance ,media_common.quotation_subject ,COVID-19 ,Management, Monitoring, Policy and Law ,Visitor management ,Protected area ,Maladaptation ,Urban Studies ,Geography ,Pandemic ,Psychological resilience ,Closure (psychology) ,Adaptation ,Adaptation (computer science) ,Socioeconomics ,Nature and Landscape Conservation ,media_common ,Research Paper - Abstract
Highlights • Protected areas were studied as spaces for adaptation to COVID-19. • The socio-psychological model of precautionary adaptation was employed. • High perceived adaptation efficacy and low adaptation cost promoted adaptation. • The ability of protected areas to assist in adaptation to pandemics was highlighted., As COVID-19 has swept across the world, governments have been prompted to order social distancing measures, from the closure of schools, restaurants and public facilities to quarantines and lockdowns. Access to and contact with nature have been suggested to help combat impacts associated with isolation measures, and a coincidental surge in the number of visitors to country parks in Hong Kong has recently been observed. The current study sought to explore the visitation of country parks as an adaptation to COVID-19 by employing the socio-psychological model of precautionary adaptation (SPMPA). Questionnaire surveys were administered in 12 country parks in Hong Kong, and a total of 600 samples were collected. A conceptual model based on the SPMPA was proposed and tested through multiple regression analysis. Significant associations between perceived severity, threat experience and adaptative behaviour were found, suggesting the possible risks of visiting country parks. However, the relationships among perceived adaptation efficacy, adaptation cost and reliance on public adaptation implied that the adaptative benefits of visiting country parks may outweigh the risks when proper visitor management measures are implemented. The findings highlighted the importance of providing accessible protected areas or other types of nature-based spaces to facilitate the adaptation of people to disease outbreaks in both the short and long run.
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- 2020
18. Epidemiological samplings for long-term HBM-studies during a pandemic situation – Experiences and lessons-learned, the German Environmental Specimen Bank during the COVID-19 pandemic.
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Bartel-Steinbach, Martina, Weber, Till, Michel, Markus, Wagner, Sylvia, Zimmermann, Heiko, Kolossa-Gehring, Marike, and Lermen, Dominik
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COVID-19 pandemic , *COVID-19 , *PANDEMICS , *SAMPLING (Process) , *ENVIRONMENTAL exposure , *PLANT protection - Abstract
For the investigation of diseases and other harmful environmental influences (e.g., chemicals) epidemiological studies rely on high quality human samples, among others. Collecting samples and data in the field can pose an enormous challenge to the study team with regard to health protection and occupational safety, especially in the context of a pandemic where there was great uncertainty about the biological risks associated with SARS-CoV-2. The German Environmental Specimen Bank (German ESB) is a key element of environmental and human biomonitoring in Germany with the aim to document and assess trends of human and environmental exposure to chemicals over time and to provide scientific data for policy decision makers. Starting with a pilot study in 1978 human samples are now collected at four sampling locations annually, while sampling is carried out with a highly standardized mobile laboratory since 2013. Due to the corona pandemic 3 of 4 ESB sampling campaigns had to be cancelled in 2020. However, a continuous sampling is crucial to generate current policy relevant data on chemical exposure. Hence, a protection and hygiene concept has been developed including COVID-19 testing with the goal to protect the health of participants and employees during sampling and to meet legal requirements, while sustaining the standardized procedures of sampling and sample preparation. The concept is based on a flexible approach to allow adjustments to changing government regulations and recommendations in the course of the pandemic. By implementing this concept, all samplings were successfully carried out in 2021 & 2022, with the pandemic still ongoing. This paper provides an example of good practice and valuable insights in how to collect human samples during a pandemic. • Conducting epidemiological sampling and data collection for the German Environmental Specimen Bank during a pandemic. • Risk Assessment & development of an infection protection & hygiene concept to conduct safe sampling in a mobile laboratory. • Rapid sample handling, Point-of-Care analytics, and on-site cryopreservation. • Lessons learned during Covid 19 epidemic for future pandemic situations. [ABSTRACT FROM AUTHOR]
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- 2024
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19. The experience of children with disabilities and their families during the COVID-19 pandemic: what lessons can we learn?
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Pennington, Lindsay, Merrick, Hannah, Allard, Amanda, Morris, Christopher, and Parr, Jeremy R.
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COVID-19 has had serious, negative impacts on children's health and development. But the impacts have not been felt equally. Disabled children and their families have been hit particularly hard. In this paper we summarize UK legislation to limit the spread of the virus and describe how services to disabled children changed as a result. We discuss the long-term deleterious impacts of changes in service provision on the health and wellbeing of disabled children and the parent carers supporting them. We close with lessons learned for resetting services to support the ongoing recovery of children and their families and recommendations for delivering services better in future emergencies to ensure that disabled children's health and wellbeing is maintained. [ABSTRACT FROM AUTHOR]
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- 2024
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20. SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype
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Kunitada Shimotohno, Nao Nishida, Takashi Gojobori, Naoki Yamamoto, Yasuo Ariumi, Rain Yamamoto, Masashi Mizokami, and Georg Bauer
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0301 basic medicine ,bp, base pair ,viruses ,0302 clinical medicine ,Genotype ,Pandemic ,I, insertion ,Prevalence ,Ethnicity ,skin and connective tissue diseases ,COVID-19, coronavirus disease 2019 ,education.field_of_study ,Predictive marker ,virus diseases ,General Medicine ,SNP, single nucleotide polymorphism ,030220 oncology & carcinogenesis ,Ang, angiotensin ,gnomAD, genome aggregation database ,ACE1 II genotype ,Research Paper ,HLA, human leukocyte antigens ,ACE, angiotensin-converting enzyme ,Population ,Biology ,Virus ,RAAS, renin angiotensin aldosterone system ,03 medical and health sciences ,Severity of illness ,ACE1 I/D polymorphism ,Genetics ,medicine ,SARS, severe acute respiratory syndrome ,Mortality ,education ,SNV, single nucleotide variants ,ARDS, acute respiratory distress syndrome ,KPGP, Korean Personal Genome Project ,D, deletion ,SARS-CoV-2 ,fungi ,MERS, Middle East respiratory syndrome ,COVID-19 ,medicine.disease ,FTP, File Transfer Protocol ,Genotype frequency ,respiratory tract diseases ,body regions ,030104 developmental biology ,VQSR, Variant Quality Score Recalibration ,Immunology ,Middle East respiratory syndrome ,TMPRSS2, transmembrane serine protease 2 ,CTSL, cathepsin L1 ,SARS-CoV-2, severe acute respiratory syndrome coronavirus-2 - Abstract
Highlights • COVID-19 infection is characterized by its prominent effect on specific ethnic group. • SARS-CoV-2 cases/mortality were negatively associated with ACE1 II genotype. • The ACE1 II genotype could be a predictive marker of SARS-CoV-2 risk and severity., Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The relentless spread and pathogenicity of the virus have become a global public health emergency. One of the striking features of this pandemic is the pronounced impact on specific regions and ethnic groups. In particular, compared with East Asia, where the virus first emerged, SARS-CoV-2 has caused high rates of morbidity and mortality in Europe. This has not been experienced in past global viral infections, such as influenza, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) and is unique to SARS-CoV-2. For this reason, we investigated the involvement of genetic factors associated with SARS-CoV-2 infection with a focus on angiotensin-converting enzyme (ACE)-related genes, because ACE2 is a receptor for SARS-CoV-2. We found that the ACE1 II genotype frequency in a population was significantly negatively correlated with the number of SARS-CoV-2 cases. Similarly, the ACE1 II genotype was negatively correlated with the number of deaths due to SARS-CoV-2 infection. These data suggest that the ACE1 II genotype may influence the prevalence and clinical outcome of COVID-19 and serve as a predictive marker for COVID-19 risk and severity.
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- 2020
21. Ideas That Plague Us: Crime and Punishment as a Pandemic Narrative.
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Erman, Irina
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This paper argues that the motif of illness runs through all of Crime and Punishment and accompanies key developments and themes to such an extent that the novel merits a reading as a plague, or pandemic, narrative. The paper examines imagery of illness and infection in Dostoevsky's novel and analyzes the way this imagery is used to underscore the danger and the infectiousness of the ideas that Dostoevsky is trying to debunk. This analysis of Crime and Punishment shows that Dostoevsky brilliantly mixes metaphors of biological and ideological infection, diagnosing ailments that still plague us to this day. [ABSTRACT FROM AUTHOR]
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- 2023
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22. Unleashing the global potential of public health: A framework for future pandemic response.
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Khorram-Manesh, Amir, Goniewicz, Krzysztof, and Burkle, Frederick M.
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Public health emergencies, especially pandemics, need to be managed globally, and on several levels, emphasizing the importance of leadership, communication, and synchronization of measures, data, and management plans in contrast to the management of the Coronavirus-19 pandemic, which illustrated diverse strategies employed by various nations. This paper aims to review and discuss whether globalized diseases in a globalized world should be managed by globalized public health. Using a systematic literature search, followed by a non-systematic literature review, selected studies were grouped into topics, and analyzed, using content analysis to enhance the conclusive results. The results present a roadmap towards a re-envisioned framework highlighting key areas of focus: data-driven decision-making, robust technology infrastructure, global cooperation, and ongoing public health education, as part of a coordinated global response. This article reveals the weaknesses of current pandemic management systems and recommends new steps to further strengthen the management of future pandemics. [ABSTRACT FROM AUTHOR]
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- 2024
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23. Understanding COVID-19 vaccine hesitancy in Canada.
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Corsten, Claire, Vang, Zoua M., Gold, Ian, Goldenberg, Maya J., Juarez, Fernanda Pérez-Gay, Weinstock, Daniel, Smith, Maxwell J., Krajden, Oren, and Solomonova, Elizaveta
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VACCINE hesitancy , *COVID-19 vaccines , *BOOSTER vaccines , *VACCINATION status , *VACCINE effectiveness , *RISK perception - Abstract
While Canada has had relatively high vaccination rates against COVID-19, specifically during earlier waves of the pandemic, vaccine hesitancy has continued to serve as a significant barrier to adequate protection against the virus and, more recently, booster vaccine uptake. This paper explores the processes underlying Canadians' perceptions of COVID-19 vaccines and their decisions to take or refuse them, as well as how public policy and health messaging about vaccination has influenced vaccination attitudes and behaviors. Our focus group interviews with 18 vaccinated and unvaccinated adult Canadians conducted during October 2021 reveal that, in some respects, COVID-19 vaccine hesitancy conforms to prior knowledge about some of the factors that affect vaccine attitudes (e.g., the influence of known medical providers) but deviates from current theoretical frameworks regarding general vaccine hesitancy. Specifically, these frameworks emphasize a lack of scientific knowledge and literacy ("knowledge deficit" accounts) or individuals' inability to incorporate rational risk perceptions into initial emotional responses to vaccines ("emotionality/irrationality" accounts). In contrast to the knowledge deficit account, we find that expressions of COVID-19 vaccine hesitancy were most frequently associated with an information surplus or inability to prioritize information from multiple and often contradictory sources. Furthermore, top-down pro-vaccination messaging often triggered significant pushback against what participants perceived as moral shaming of the unvaccinated. Our findings demonstrate the necessity for a new framework to understand and address vaccine hesitancy. A better theoretical account of vaccine hesitancy has important implications for future vaccination efforts, specifically within the context of new variants and low booster vaccination rates in Canada. [ABSTRACT FROM AUTHOR]
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- 2023
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24. Linear and non-linear dynamics of the epidemics: System identification based parametric prediction models for the pandemic outbreaks.
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Tutsoy, Onder and Polat, Adem
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COVID-19 ,SYSTEM identification ,HEALTH facilities ,PANDEMICS ,PREDICTION models ,PARAMETRIC modeling - Abstract
Coronavirus disease 2019 (COVID-19) has endured constituting formidable economic, social, educational, and phycological challenges for the societies. Moreover, during pandemic outbreaks, the hospitals are overwhelmed with patients requiring more intensive care units and intubation equipment. Therein, to cope with these urgent healthcare demands, the state authorities seek ways to develop policies based on the estimated future casualties. These policies are mainly non-pharmacological policies including the restrictions, curfews, closures, and lockdowns. In this paper, we construct three model structures of the S p I n I t I b D-N (suspicious S p , infected I n , intensive care I t , intubated I b , and dead D together with the non-pharmacological policies N) holding two key targets. The first one is to predict the future COVID-19 casualties including the intensive care and intubated ones, which directly determine the need for urgent healthcare facilities, and the second one is to analyse the linear and non-linear dynamics of the COVID-19 pandemic under the non-pharmacological policies. In this respect, we have modified the non-pharmacological policies and incorporated them within the models whose parameters are learned from the available data. The trained models with the data released by the Turkish Health Ministry confirmed that the linear S p I n I t I b D-N model yields more accurate results under the imposed non-pharmacological policies. It is important to note that the non-pharmacological policies have a damping effect on the pandemic casualties and this can dominate the non-linear dynamics. Herein, a model without pharmacological or non-pharmacological policies might have more dominant non-linear dynamics. In addition, the paper considers two machine learning approaches to optimize the unknown parameters of the constructed models. The results show that the recursive neural network has superior performance for learning nonlinear dynamics. However, the batch least squares outperforms in the presence of linear dynamics and stochastic data. The estimated future pandemic casualties with the linear S p I n I t I b D-N model confirm that the suspicious, infected, and dead casualties converge to zero from 200000, 1400, 200 casualties, respectively. The convergences occur in 120 days under the current conditions. • We construct three S p I n I t I b D-N model structures; namely, linear S p I n I t I b D-N model, non-linear S p I n I t I b D-N model, and strongly non-linear S p I n I t I b D-N model to reveal the linear and non-linear characters of the COVID-19 casualties. To the best of our knowledge, this is the first paper examining the linear and non-linear properties of a pandemic disease. • We modify the non-pharmacological policies based on their changing characters with the occurrence of the second peak in the COVID-19 casualties. Re-opening the schools partial-by-partial and imposed self-curfews, for instance, are modelled and incorporated into the S p I n I t I b D-N models. • We enrich the SpID-N model with the intensive care I t and intubated I b , which will greatly help to estimate the hospital requirements. [ABSTRACT FROM AUTHOR]
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- 2022
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25. Cascading risks, interdependent rights, and the progression of vulnerability in the context of pandemic containment measures: Implications for anticipatory action and the humanitarian-development nexus.
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Scott, Matthew
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This paper articulates a human rights-based approach to addressing cascading risks in the context of pandemic containment measures. It sets out to highlight how the principle that human rights are interdependent and interrelated, reflected in normative standards articulated by human rights treaty body mechanisms, can inform anticipatory action and work at the humanitarian-development nexus. Grounding a human rights-based approach in the political-ecological understanding of the progression of vulnerability, it considers how lockdown interfered with the right to freedom of movement and the right to work, which in turn had cascading effects on the right to the highest attainable standard of physical and mental health, the right to adequate housing and the right to water and sanitation, amongst others. Informed by Scott et al.'s (2023) Framework for Integrating Human Rights and Gender Equality (FIRE), the paper outlines specific entry points for integrating this approach at points along the humanitarian-development nexus continuum, grounded in an appreciation of root causes, dynamic pressures and unsafe conditions characteristic of the progression of vulnerability. The article calls for pilot studies to explore the impact of an integrated human rights-based approach to cascading pandemic risk. • The paper is the first to adopt a human rights-based approach to cascading risks in a pandemic preparedness for response context. • The paper argues that an appreciation of the interdependence of substantive human rights can help to guide decisions regarding pandemic containment measures, encouraging systematic consideration of cascading risks across multiple civil and political, and economic, social and cultural rights. • The article shows how normative human rights standards can inform anticipatory action and work at the wider humanitarian-development nexus. [ABSTRACT FROM AUTHOR]
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- 2024
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26. Resumption of Cosmetic Surgery During COVID – Experience of a Specialised Cosmetic Surgery Day-case Hospital.
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Imam, Syeda Zoha, Karanasios, George, Khatib, Manaf, Cavale, Naveen, Amar, Olivier, and Mayou, Bryan
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The novel coronavirus outbreak (COVID-19) in 2019 resulted in the suspension of all elective hospital procedures during the height of the pandemic in the UK. The Clinic in London is one of the first day-case hospitals to resume cosmetic surgery in a post-COVID-19 clinical environment, whilst also employing the use of virtual consultations. Details of the protocol implemented by the Clinic to allow the safe resumption of cosmetic surgery are stated in this paper. The volume of procedures at the Clinic saw a significant increase post-lockdown; reasons as to why this occurred are also explored in this paper. The disruption of cosmetic practice during lockdown can be said to have resulted in a backlog of procedures once lockdown restrictions began to ease. Whilst this may be true, we believe that there are other confounding factors regarding what may have influenced the rise in cosmetic surgery during the pandemic, including the privacy of working from home and the increased exposure to video conferencing software. [ABSTRACT FROM AUTHOR]
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- 2021
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27. The economic impacts of COVID-19 and city lockdown: Early evidence from China.
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Wu, Jianxin, Zhan, Xiaoling, Xu, Hui, and Ma, Chunbo
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CITIES & towns , *ECONOMIC recovery , *STAY-at-home orders , *ECONOMIC impact , *VIRAL transmission , *CITY traffic , *URBAN density - Abstract
• Chinese economy hit hard by both the pandemic and city lockdown. • City lockdown explains 2.8 percentage points of the GDP loss. • Significant spatial spill-over effects of the pandemic but not lockdown. • Reduced labor mobility, land supply, and entrepreneurship are main mechanisms. • Significant heterogeneity across cities in post-pandemic economic recovery. As the first major developing country heavily struck by the COVID-19 pandemic, China adopted the world's most stringent lockdown interventions to contain the virus spread. Using macro- and micro-level data, this paper shows that both the pandemic and lockdown policies have had negative and significant impacts on the economy. Gross regional product (GRP) fell by 9.5 and 0.3 percentage points in cities with and without lockdown interventions, respectively. These impacts represent a dramatic recession from China's average growth of 6.74% before the pandemic. The results indicate that lockdown explains 2.8 percentage points of the GDP loss. We also document significant spill-over effects of the pandemic in adjacent areas but no such effects of lockdown. Reduced labor mobility, land supply, and entrepreneurship are among the most significant mechanisms underpinning the impacts of the pandemic and lockdown. Cities with higher share of secondary industry, higher traffic intensity, lower population density, lower internet access, and lower fiscal capacity suffered more. However, these cities seem to have recovered well from the recession and quickly closed the economic gap in the aftermath of the pandemic and city lockdown. Our findings have broader implications for the global interventions in pandemic containment. [ABSTRACT FROM AUTHOR]
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- 2023
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28. The estimations of the COVID-19 incubation period: A scoping reviews of the literature.
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Zaki, Nazar and Mohamed, Elfadil A.
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A novel coronavirus (COVID-19) has taken the world by storm. The disease has spread very swiftly worldwide. A timely clue which includes the estimation of the incubation period among COVID-19 patients can allow governments and healthcare authorities to act accordingly. to undertake a review and critical appraisal of all published/preprint reports that offer an estimation of incubation periods for COVID-19. This research looked for all relevant published articles between the dates of December 1, 2019, and April 25, 2020, i.e. those that were related to the COVID-19 incubation period. Papers were included if they were written in English, and involved human participants. Papers were excluded if they were not original (e.g. reviews, editorials, letters, commentaries, or duplications). COVID-19 Open Research Dataset supplied by Georgetown's Centre for Security and Emerging Technology as well as PubMed and Embase via Arxiv, medRxiv, and bioRxiv. A data-charting form was jointly developed by the two reviewers (NZ and EA), to determine which variables to extract. The two reviewers independently charted the data, discussed the results, and updated the data-charting form. Screening was undertaken 44,000 articles with a final selection of 25 studies referring to 18 different experimental projects related to the estimation of the incubation period of COVID-19. The majority of extant published estimates offer empirical evidence showing that the incubation period for the virus is a mean of 7.8 days, with a median of 5.01 days, which falls into the ranges proposed by the WHO (0–14 days) and the ECDC (2–12 days). Nevertheless, a number of authors proposed that quarantine time should be a minimum of 14 days and that for estimates of mortality risks a median time delay of 13 days between illness and mortality should be under consideration. It is unclear as to whether any correlation exists between the age of patients and the length of time they incubate the virus. [ABSTRACT FROM AUTHOR]
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- 2021
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29. Urban transport policies in the time of pandemic, and after: An ARDUOUS research agenda.
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Corazza, Maria Vittoria and Musso, Antonio
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URBAN policy , *SCIENTIFIC knowledge , *VIRAL transmission , *MEDICAL sciences , *PANDEMICS , *FEDERAL government , *STANDARDIZATION - Abstract
While the virus keeps spreading worldwide and mass vaccinations are yet to come, transport policy makers face a dilemma: how is mobility changing? The situation is not unprecedented. But, unlike in past times when medical science was at early stages and little technology was available, counteractions currently undertaken by national and supranational governments integrate highest medical knowledge and technological skills with new, fast-adaptive lifestyles and transport patterns. The paper moves from this to present some key issues, synthesized by the ARDUOUS acronym (Adjustment , Redesign, Domesticity, Unsharing, Organization, Unsustainability, Standardization), to cope with the present situation and give rise to a new approach in the future urban transport policies. The paper, after analyzing the contemporary situation and its implications, addresses each issue in terms of both current limitations and potential to improve the future transport policies. Some directions are proposed and commented, to advance and create a reference for further transport policies, within the general research goal to contribute to advance scientific knowledge in this new transportation study topic. • Individual mobility was severely impacted by the pandemic. • Safe transport systems are crucial in mitigating the spread risks. • A new policy approach is needed to provide safe mobility for all. • Domesticity, Unsharing, Unsustainability are the risks to face in the new normal. • Adjustment, Redesign, Organization and Standardization are needed to create preparedness. [ABSTRACT FROM AUTHOR]
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- 2021
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30. Will multinational enterprises contribute to Poland's economic resilience and recovery during and post COVID-19 pandemic.
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Umiński, Stanisław and Borowicz, Aleksandra
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COVID-19 pandemic ,FOREIGN investments ,INTERNATIONAL business enterprises ,ECONOMIC recovery ,CAPITAL movements ,PANDEMICS - Abstract
Being part of the integration grouping, Poland benefits from the geographic, cultural and cognitive proximity to the largest investors. Making reference to the vulnerability concept and the changing nature of globalisation, presenting stylised facts on foreign direct investment (FDI) and comparing FDI to other foreign capital flows – the paper aims to predict the role of foreign-owned entities (FOEs) in Poland in the process of the post-pandemic recovery. Referring to the performance of FOEs in the 2008 crisis and comparing the volatility of various foreign inflows, FDI shall be perceived as a factor stabilising Poland's economy in a current pandemic slowdown and stimulating the post-pandemic recovery. FOEs reveal a premium over the domestic entities, and therefore their activity in Poland is expected to be helpful in the post-pandemic recovery. The paper formulates recommendations to attract foreign investors to Poland at the post-pandemic time. [ABSTRACT FROM AUTHOR]
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- 2021
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31. Outcomes of firm resilience in wild card crises—Country, industry, and firm effects in the Covid-19 crisis.
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Safón, Vicente, Iborra, María, and Escribá-Esteve, Alejandro
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In this paper, we examine to what extent external factors (country and industry) and internal factors (capabilities of firms) explain firm resilience outcomes during the first and toughest months of a wild card crisis. Our study uses multivariable regressions on a sample of 1,180 firms. Using evidence from a survey of 58 countries and 17 industries, our results show that, contrary to the mainstream, external effects play a more significant role in explaining resilience outcomes than internal effects. They also highlight the important role of firms' adaptive capabilities in the initial phase of crises. The study contributes to the existing literature by shedding light on the importance of resilience and on the relative influence of internal and external factors in predicting resilience outcomes in the face of a global shock. The paper highlights the need for further research into performance variance in the very short run when firms face a wild card situation. It also discusses implications for governments and firms in improving their resilience capabilities and emphasizes the importance of ensuring that aid reaches small firms and that managers prepare firms with excess liquidity for times of crisis. [ABSTRACT FROM AUTHOR]
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- 2024
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32. Pakistan's healthcare preparedness after the NIH warned of a new diphtheria strain and Covid-19 variation.
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Muzzamil, Muhammad, Naz, Simra, Mumtaz, Hassan, and Omair, Wajiha
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In this paper, we examine the current crisis of regarding preparedness of healthcare industries in Pakistan, analyzing the causes, effects, and potential recommendations to this problem. Highlighting the efforts and issues surrounding this topic is necessary for developing and implementing research-based solutions that accurately reflect the current state of the healthcare industry. This short overview is prepared in accordance with accepted practices in published studies around the world. Our findings were based on a search of the literature databases PubMed, Google Scholar, Journals Online, and the Internet Library. Searching for "Healthcare Preparedness in Pakistan" yielded the expected results. Particularly of interest to the researchers was the question of why, despite efforts to boost vaccination rates and emergency immunization response capacities in the event of epidemics, progress on SDG3 immunization indicators has been minimal. Immunization is critically important because vaccine-preventable diseases pose a significant risk to the general population. Pakistan's authorities and government should take deliberate action to increase immunization rates. Particularly disadvantaged countries and regions are hit the worst by climate change. Pakistan continues to be hit hard by diseases like acute watery diarrhea, dengue fever, malaria, and COVID-19 are on the rise as a result of the flooding, especially in shelters and areas where water and sanitation systems have been affected. After devastating floods in KP, Sindh, and Punjab, over 70 suspected cases of diphtheria were reported. Diphtheria epidemics illustrate the precarious position of flood victims. It would be catastrophic if the newly found diphtheria strain or the covid-19 variation reached the underserved flood victims. Immunization protects against life-threatening illnesses so its government responsibility to improve immunization rates in Pakistan. [ABSTRACT FROM AUTHOR]
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- 2023
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33. The global burden of trauma during the COVID-19 pandemic: A scoping review.
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Waseem, S., Nayar, S.K., Hull, P., Carrothers, A., Rawal, J., Chou, D., and Khanduja, V.
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Purpose; The COVID-19 pandemic has necessitated profound adaptations in the delivery of healthcare to manage a rise in critically unwell patients. In an attempt to slow the spread of the virus nationwide lockdown restrictions were introduced. This review aims to scope the literature on the impact of the pandemic and subsequent lockdown on the presentation and management of trauma globally. Methods; A scoping review was conducted in accordance with PRISMA-ScR guidelines. A systematic search was carried out on the Medline, EMBASE and Cochrane databases to identify papers investigating presentation and management of trauma during the COVID-19 pandemic. All studies based on patients admitted with orthopaedic trauma during the COVID-19 pandemic were included. Exclusion criteria were opinion-based reports, reviews, studies that did not provide quantitative data and papers not in English. Results; 665 studies were screened, with 57 meeting the eligibility criteria. Studies reported on the footfall of trauma in the UK, Europe, Asia, USA, Australia and New Zealand. A total of 29,591 patients during the pandemic were considered. Mean age was 43.7 years (range <1–103); 54.8% were male. Reported reductions in trauma footfall ranged from 20.3% to 84.6%, with a higher proportion of trauma occurring secondary to interpersonal violence, deliberate self-harm and falls from a height. A decrease was seen in road traffic collisions, sports injuries and trauma occurring outdoors. There was no significant change in the proportion of patients managed operatively, and the number of trauma patients reported to be COVID-19 positive was low. Conclusion; Whilst the worldwide COVID-19 pandemic has caused a reduction in the number of trauma patients; the services managing trauma have continued to function despite infrastructural, personnel and pathway changes in health systems. The substantial effect of the COVID-19 pandemic on elective orthopaedics is well described, however the contents of this review evidence minimal change in the delivery of effective trauma care despite resource constraints during this global COVID-19 pandemic. [ABSTRACT FROM AUTHOR]
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- 2021
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34. The impact of COVID-19 on pharmacy transitions of care services.
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Herzik, Kristen A. and Bethishou, Laressa
- Abstract
COVID-19 has necessitated alterations to the delivery of healthcare services. Modifications include those made to improve patient and healthcare worker safety such as the use of personal protective equipment. Pharmacy services, specifically pharmacy transitions of care services have not been immune to change which have brought along their own set of unique challenges to consider. This paper discusses how COVID-19 has impacted the delivery of pharmacy transitions of care services with real world examples from Sharp Grossmont Hospital and Hoag Memorial Hospital Presbyterian. Procedures implemented to minimize the spread and contraction of COVID-19 such as minimized patient contact and altered visitor policies have made it more challenging to obtain a best possible medication list the patient was taking prior to arrival to the hospital which has lead to an increased reliance on secondary sources to complete medication histories. Regarding discharge prescriptions, preference has shifted to the use of electronic vs. hard copy prescriptions, mail order, and utilization of med to bed programs and other hospital medication delivery services to limit patient contact in outpatient pharmacies. An improved effort to resolve medication acquisition issues prior to discharge utilizing patient assistance programs and other hospital programs to cover the cost of medications for COVID positive patients under certain circumstances has been seen. This paper highlights the important role pharmacists can play in providing effective communication, supporting continuity of care, and advocating for patient engagement and empowerment during transitions of care in the COVID-19 pandemic. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
35. Home-made masks with filtration efficiency for nano-aerosols for community mitigation of COVID-19 pandemic.
- Author
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Li, I.W.-s., Fan, J.K.-m., Lai, A.C.-k., and Lo, C.-m.
- Subjects
- *
AEROSOLS , *ALCOHOLS (Chemical class) , *COMMERCIAL product evaluation , *PREVENTION of communicable diseases , *ELECTRON microscopy , *ENVIRONMENTAL engineering , *EXPERIMENTAL design , *FILTERS & filtration , *LAMINAR flow , *MATERIALS testing , *NANOPARTICLES , *SCIENTIFIC observation , *DESCRIPTIVE statistics , *COVID-19 , *COVID-19 pandemic - Abstract
The novel coronavirus disease 2019 (COVID-19) epidemic that emerged in December 2019 has rapidly evolved in recent months to become a worldwide and ongoing pandemic. Shortage of medical masks remains an unresolved problem. This study aims to investigate the filtration efficiency (FE) of home-made masks that could be used as alternatives for community mitigation of COVID-19. Experimental observational analytic study. The FE of home-made masks and medical masks (as the control) were tested under laminar flow within a scaled air duct system using nebulised NaCl aerosols sized 6–220 nm. The size-resolved NaCl aerosol count was measured using a scanning mobility particle-sizer spectrometer. Home-made masks with an external plastic face shield also underwent a splash test. In addition, the fibre structures of medical masks were studied under an electron microscope after treatment with either 75% alcohol or soap and water at 60 °C. The FE of the home-made masks at 6–200 nm were non-inferior to that of medical masks (84.54% vs 86.94%, P = 0.102). Both types of masks achieved an FE of 90% at 6–89 nm. A significantly higher FE was achieved when one piece of tissue paper was added adjacent to the inner surface of the medical mask than medical mask alone (6–200 nm: 91.64% vs 86.94%, P < 0.0001; 6–89 nm: 94.27% vs 90.54%, P < 0.0001; 90–200 nm: 82.69% vs 73.81%, P < 0.0001). The plastic face shield prevented the home-made mask from fluid splash. The fibre structures of the external surface of medical masks were damaged after treatment with either 75% alcohol or soap and water at 60 °C. The home-made masks in this study, which were made of one piece of tissue paper and two pieces of kitchen towels, layered from face to external, had an FE at 6–200 nm non-inferior to that of medical mask materials, which had a certified FE of ≥95% at 3 μm. In the current COVID-19 pandemic with the shortage of medical masks, these home-made masks combined with an external plastic shield could be used as an alternative to medical masks for community mitigation. In addition, one piece of tissue paper could be placed adjacent to the inner surface of a medical mask to prolong effective lifespan of the medical mask. These demand reduction strategies could be used to reserve medical masks for use in healthcare and certain high-risk community settings, such as symptomatic persons, caregivers and attendees to healthcare institutions. • Our home-made masks have filtration efficiency comparable to medical masks. • They may be used as alternatives in low-risk community settings. • Plastic face shields may be used in situations when social distancing and/or face masks are not feasible. • Decontamination of medical masks with 75% alcohol or soap and water damages the fibres and is not recommended. • Community mitigation measures are an important part of the global efforts in combating COVID-19. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
36. Did the pandemic bring new features to counter-urbanisation? Evidence from Estonia.
- Author
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Tammaru, Tiit, Kliimask, Jaak, Kalm, Kadi, and Zālīte, Jānis
- Subjects
COVID-19 pandemic ,CAPITAL cities ,PANDEMICS ,HUMAN migration patterns ,RURAL geography ,POPULATION aging - Abstract
This paper aims to shed new light on changes in counter-urbanisation over the past three decades. A specific focus will be placed on new features of domestic migration to non-metropolitan rural areas which have become apparent during the global coronavirus pandemic. We focus on the intensity, origins, and destinations of counter-urban moves, and on the individual characteristics of counter-urban movers. Based on a case study of Estonia, our main findings show, firstly, that urbanisation has been the predominant migration trend across the past thirty years, with the main destination of domestic migrants being the capital city and its urban region. Secondly, we find that counter-urban moves have gained importance over time and especially during the periods of economic bust. The most important new features of counter-urbanisation during the pandemic relate to the increased migration of families with children and people who have high-income occupations to non-metropolitan rural areas. These new features of domestic migration could serve to slow down or even reverse the long-term problem of population aging in the countryside and the loss of educated people there. • Analysis of counter-urbanisation between over the past three decades. • New features of counter-urban moves. • Pandemic has reinforced many long-term trends in counter-urban moves. • Counter-urban moves of families improve the demographic profile of rural areas. • Counter-urban moves of higher-income earners improve the social profile of rural areas. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
37. What has cardiac rehabilitation looked like in the COVID-19 pandemic: Lessons learned for the future.
- Author
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Ozemek, Cemal, Berry, Robert, Bonikowske, Amanda R., German, Charles, and Gavic, Anne M.
- Abstract
The global coronavirus disease 2019 (COVID-19) pandemic prompted widespread national shutdown, halting or dramatically reducing the delivery of non-essential outpatient services including cardiac rehabilitation (CR). Center-based CR services were closed for as few as two weeks to greater than one year and the uncertainty surrounding the duration of the lockdown phase prompted programs to consider programmatic adaptations that would allow for the safe and effective delivery of CR services. Among the actions taken to accommodate in person CR sessions included increasing the distance between exercise equipment and/or limiting the number of patients per session. Legislative approval of reimbursing telehealth or virtual services presented an opportunity to reach patients that may otherwise have not considered attending CR during or even before the pandemic. Additionally, the considerable range of symptoms and infection severity as well as the risk of developing long lasting, debilitating symptoms has complicated exercise recommendations. Important lessons from publications reporting findings from clinical settings have helped shape the way in which exercise is applied, with much more left to discover. The overarching aim of this paper is to review how programs adapted to the COVID-19 pandemic and identify lessons learned that have positively influenced the future of CR delivery. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
38. How do pandemics affect intercity air travel? Implications for traffic and environment.
- Author
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Wang, Chunan and Jiang, Changmin
- Subjects
- *
AIR travel , *TRAFFIC flow , *TRAFFIC density , *TRANSPORTATION industry , *CARBON emissions , *CHOICE of transportation - Abstract
This paper investigates how a pandemic affects the distribution of traffic between public and private transport and the emissions from the transport sector. By assuming that there exists higher health risk of traveling in public transport than in private transport and using air transport and private cars as examples, we find the following results. First, the effects of a pandemic on the traffic volumes of airline services and private cars depend crucially on, for instance, the willingness-to-pay of travelers, the degree of substitution between transport modes, the demand-side network effect (via schedule delays), and the supply-side network effect (via the economies of traffic density). In particular, heterogeneous effects of the pandemic on the traffic volumes and flight frequencies of different airline services are found. Second, the total transport-related CO2 emissions decrease after the pandemic if the CO2 emissions per air traveler (or per flight) are sufficiently high, or the degree of substitution between airline services and private cars is sufficiently low. Third, numerical examples on the change in price of car travel and the introduction of high-speed rail show consistent insights. Finally, several policy implications are discussed. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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39. Mining text on Coronavirus.
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Beltrán-Oicatá, Cristian O., Gaitán-Angulo, Mercedes, Lis-Gutiérrez, Melissa, and Naveda, Alexa Senior
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COVID-19 ,NEWSPAPER circulation ,SARS-CoV-2 ,CORONAVIRUSES ,DATA analysis ,PERFORMING arts - Abstract
This document describes the behavior of the production of academic papers and high circulation newspapers, published under the terms "Coronavirus, Covid-19 or SARS-CoV-2". The purpose of this paper is to employ text mining techniques and qualitative data analysis for pattern identification (Dobrzyński, Dziekoński, Krzysztof, & Jurczuk, 2013; Westergaard, Staerfeldt, Tønsberg, Jensen, & Brunak, 2018). The interest of this study arises from the importance of this topic today and its relationship with the economy, business and society. As a result, the production of scientific papers has been led by the United States, China and Russia. In Latin America, Brazil is the country with the highest scientific output on this subject. The analysis of newspaper articles focusing on economic and business issues showed the work between large companies, the government and the community, as well as companies with businesses and the need to adapt to constant change in the face of the crisis of labor and production. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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- View/download PDF
40. Research on demand forecasting and distribution of emergency medical supplies using an agent-based model.
- Author
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Zhou, Xin and Liao, Wenzhu
- Subjects
- *
DEMAND forecasting , *MEDICAL supplies , *MEDICAL emergencies , *THERAPEUTICS , *RESOURCE allocation , *DEATH rate , *CROP allocation - Abstract
The global health crisis caused by SARS-CoV-2 since 2019 has emphasized the critical significance of effective disease detection and treatment in minimizing infection rates and fatalities, as well as halting the spread of pandemics. During an outbreak, individuals suspected of being infected require a significant amount of testing resources, while those confirmed to be infected demand substantial treatment resources. Hence, this paper is dedicated to presenting a new pandemic model that enables joint forecasting and allocation of resources for testing and treatment. The proposed model in this paper is an innovative agent-based epidemic compartmental model, which also incorporates a mixed integer model. It integrates novel features based on crucial disease characteristics, such as self-healing for asymptomatic or mild-symptomatic cases, varying infection risk levels among different groups, and the inclusion of secondary infections. Moreover, the solutions of the joint allocation model are compared with those of the independent allocation model, which entails considering resource interactions rather than allocating each resource independently. Furthermore, the validity of this model was confirmed through real-world data obtained during the SARS-CoV-2 outbreak in China. The findings offer valuable insights into the impact of intervention levels and duration, joint allocation schemes, as well as optimal allocation of test and treatment resources on cross-regional transmission of the pandemic. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
41. Student information use during the COVID-19 pandemic.
- Author
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Howard, Heather A., Bochenek, Annette, Mayhook, Zoeanna, Trowbridge, Trena, and Lux, Steven
- Subjects
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COVID-19 pandemic , *COLLEGE students , *SOCIAL media , *INFORMATION literacy , *MIXED methods research - Abstract
Since early 2020, life for students has changed tremendously. It has been a time of stress, turmoil, and trauma for students. Researchers from a large Midwestern university wanted to determine how student information use has changed during the COVID-19 pandemic. This paper examines the results of a mixed-methods study undertaken in 2021 using surveys and follow-up focus groups to determine if and how student information use has changed. To answer this, we explored student use of news sources, social media sources, political affiliations, and information responses, coupled with to what extent these factors demonstrate or impact potential changes in information use. We also addressed changes in the frequency of use, as well as the types of resources consulted, pertaining to information use of traditional and social media sources. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
42. Evaluation of streaming video usage in a university library before, during, and after the COVID-19 pandemic lockdown.
- Author
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Foley, Marianne
- Subjects
- *
COVID-19 pandemic , *STREAMING video & television , *STAY-at-home orders , *ACADEMIC librarians , *COLLECTION development in libraries - Abstract
As the COVID-19 pandemic lockdown and remote course delivery recede in the rear-view mirror, academic librarians look to what the future holds for streaming video. During 2020 and 2021, library-funded streaming video requests soared while library budgets declined. Librarians are concerned that this trend will continue beyond budgetary limits. This paper describes an analysis of streaming video usage from 2019 through 2022 at California State University, Fresno. The results provide evidence that the elevated growth rate is tapering off at this institution, but the medium remains popular. The impact of streaming media on library budgets and collection development policies is also discussed. Our evaluation is distinguished by the inclusion of data from before, during, and after the pandemic lockdown. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
43. COVID-19 differentiated measures for unvaccinated individuals: The need for clear goals and strong justifications.
- Author
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Chuan Voo, Teck, Savulescu, Julian, Schaefer, Owen, Ho Zhi Ling, Abel, and Tam, Clarence C.
- Subjects
- *
VACCINATION , *VACCINATION status , *INDIVIDUAL needs , *COVID-19 , *COVID-19 vaccines , *ANTI-vaccination movement - Abstract
Numerous countries and jurisdictions have implemented differential COVID-19 public health restrictions based on individual vaccination status to mitigate the public health risks posed by unvaccinated individuals. Although it is scientifically and ethically justifiable to introduce such vaccination-based differentiated measures as a risk-based approach to resume high-risk activities in an ongoing pandemic, their justification is weakened by lack of clarity on their intended goals and the specific risks or potential harms they intend to mitigate. Furthermore, the criteria for the removal of differentiated measures may not be clear, which raises the possibility of shifting goalposts without clear justification and with potential for unfairly discriminatory consequences. This paper seeks to clarify the ethical justification of COVID-19 vaccination-based differentiated measures based on a public health risk-based approach, with focus on their deployment in domestic settings. We argue that such measures should be consistent with the principal goal of COVID-19 vaccination programmes, which is to reduce the incidence of severely ill patients and associated healthcare burdens so as to protect a health system. We provide some considerations for the removal of vaccination-based differentiated measures based on this goal. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
44. A comprehensive meta-analysis and systematic review of breath analysis in detection of COVID-19 through Volatile organic compounds.
- Author
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Long, Grace A., Xu, Qian, Sunkara, Jahnavi, Woodbury, Reagan, Brown, Katherine, Huang, Justin J., Xie, Zhenzhen, Chen, Xiaoyu, Fu, Xiao-an, and Huang, Jiapeng
- Subjects
- *
VOLATILE organic compounds , *SARS-CoV-2 Delta variant , *COVID-19 , *SARS-CoV-2 Omicron variant , *COVID-19 pandemic , *SONICATION , *CUCUMBER mosaic virus - Abstract
The COVID-19 pandemic had profound global impacts on daily lives, economic stability, and healthcare systems. Diagnosis of COVID-19 infection via RT-PCR was crucial in reducing spread of disease and informing treatment management. While RT-PCR is a key diagnostic test, there is room for improvement in the development of diagnostic criteria. Identification of volatile organic compounds (VOCs) in exhaled breath provides a fast, reliable, and economically favorable alternative for disease detection. This meta-analysis analyzed the diagnostic performance of VOC-based breath analysis in detection of COVID-19 infection. A systematic review of twenty-nine papers using the grading criteria from Newcastle-Ottawa Scale (NOS) and PRISMA guidelines was conducted. The cumulative results showed a sensitivity of 0.92 (95 % CI, 90 %-95 %) and a specificity of 0.90 (95 % CI 87 %-93 %). Subgroup analysis by variant demonstrated strong sensitivity to the original strain compared to the Omicron and Delta variant in detection of SARS-CoV-2 infection. An additional subgroup analysis of detection methods showed eNose technology had the highest sensitivity when compared to GC-MS, GC-IMS, and high sensitivity-MS. Overall, these results support the use of breath analysis as a new detection method of COVID-19 infection. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
45. Pandemic babies: A systematic review of the association between maternal pandemic-related stress during pregnancy and infant development.
- Author
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Nazzari, Sarah, Pili, Miriam Paola, Günay, Yaren, and Provenzi, Livio
- Subjects
- *
INFANT development , *PANDEMICS , *COVID-19 pandemic , *PREGNANCY , *PRENATAL exposure , *PRENATAL depression - Abstract
The COVID-19 pandemic, with its far-reaching influence on daily life, constituted a highly stressful experience for many people worldwide, jeopardizing individuals' mental health, particularly in vulnerable populations such as pregnant women. While a growing body of evidence links prenatal maternal stress to biological and developmental alterations in offspring, the specific impact of prenatal exposure to maternal pandemic-related stress (PRS) on infant development remains unclear. A comprehensive literature search was performed in October 2023 according to the PRISMA guidelines, which yielded a total of 28 records. The selected papers investigated a vast range of developmental and biological outcomes in the offspring with large methodological variations. The reviewed studies showed mixed results. Either direct associations between maternal PRS during pregnancy and infant temperament and socio-emotional development, or indirect links, mediated by maternal mental health, emerged in most studies. Furthermore, maternal PRS was associated with epigenetic and brain alterations in the offspring, although studies were limited in number. Collectively, the reviewed findings contribute to a deeper understanding of the role of early adverse exposures on infant development. • The COVID-19 pandemic constituted a critical period during which prenatal stressors may have been amplified. • Prenatal pandemic stress was linked to infant temperament/socio-emotional development. • Maternal mental health was often a critical mediator of the association. • Prenatal pandemic stress was related to epigenetic and brain alterations in offspring. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
46. Re-imagining delightful experiences in "New Normal" conditions: A systematic critical review and future research agenda.
- Author
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Le, Truc H., Le, Dung (Jenny), Nimri, Rawan, and Quach Thaichon, Sara
- Abstract
Disasters and crises, including the COVID-19 pandemic, have created an uncertain and challenging environment, particularly for the hospitality and service-based industries, forcing managers to seek effective approaches in designing and staging delightful experiences in post-crisis conditions. This paper aims to advance research in delightful customer experiences in the hospitality and service-based industries in the post-crisis "new normal" conditions by (1) systematically and critically reviewing non-crisis and pre-pandemic findings on customer delight, (2) updating and structuring new findings in times of crisis and during the pandemic, and (3) thus suggesting new ways of conceptualising customer delight in the "new normal" conditions. Several conceptual gaps are identified based on this systematic critical review, which eventuates the development of a dual-pathway framework in the "new normal" context. Following this, several future research directions and practical implications for more effective delightful experience management are provided. • Systematically review relevant research on delightful experiences management. • Update and structure new findings in times of crisis, during and post-pandemic. • Clarify 6 relevant research gaps in the literature. • Offer a conceptual framework of delightful experiences. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
47. Securitization for common health.
- Author
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Ciardiello, Francesco, Di Lorenzo, Emilia, Menzietti, Massimiliano, and Sibillo, Marilena
- Subjects
- *
INVESTORS , *PUBLIC health infrastructure , *BOND market , *CATASTROPHE bonds , *INSURANCE policies , *CAPITAL market , *BOND prices - Abstract
Securitization is the process of turning a financial asset, such as a loan or a mortgage, into a security that can be bought and sold on the market. Insurance-linked securities have been developed in order to foster the risk-transfer from insurers to capital market. In the context of pandemics or health crisis, securitization has been used to raise funds for crucial healthcare infrastructure and resources. However, securitization can also play a role in lowering infectious rates of pandemics as a part of risk mitigation strategies. Securitization can be engineered at higher standards and levels involving different actors. In the current paper, we propose an operational securitization mechanism based on the previous work by Di Lorenzo and Sibillo (2020) where a bond with coupon linked to the infection rate is introduced in order to reduce the risk exposure of an insurer offering health coverage. The combination of bond and health policies is structured in such a way to foster the economic operators (insureds, insurer, investors on capital market) to reduce the pandemic risk. It follows that companies might guarantee collective health for their workers if they subscribe insurance policies. Indeed, issuing such a bond on the market is challenging, due to poor market liquidity and, then, due to difficulties in pricing. In these regards, we value the pandemic-linked bond via an approach based on an inter-temporal CRRA utility function that, in its turn, determines a certain equivalent financial bond. The comparison values the pandemic-linked bond at varying with investors' risk-aversion and sustainable-projects desirability. This provides an estimation of the risk-transfer cost for the insurers. • A novel insurance method for mitigating the risk of health crisis • Approach of insurance as governance • The proposed insurance scheme includes securitization • Health spillovers on individuals who have not contributed to the whole welfare • Market-sustainability supported via a comparison with a certain bond [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
48. Volunteering intentions during social crises: The role of considering the welfare of others and consequences of own behavior.
- Author
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Nowakowska, Iwona and Pozzi, Maura
- Abstract
In the current paper, we investigate how people with experience with volunteering in their lifetime intend to engage in hypothetical crisis volunteering in the future. We took into account two types of hypothetical social crises: a pandemic and a refugee crisis. We suggest that individual differences in considering the welfare of others (social value orientation) and consideration of future/immediate consequences play a role in the volunteer responses to crises. We also control for the willingness to volunteer in the proximal (a month) and distal (3 years) future, gender, age, and length of volunteer experience. We conducted two survey-based online studies in October 2023. We recruited N = 287 people for Study 1 (Poland) and N = 231 for Study 2 (Italy). Our results suggested that people who declare they want to remain volunteers intend to engage during social crises, but not necessarily in a proactive way. Furthermore, consideration of future consequences can result in proactivity, which was especially visible in the Italian sample. Consideration of immediate consequences can have twofold correlates – one might be the engagement in volunteering in case of a sudden emergency or refraining from the voluntary activity. These results can be used by people leading volunteer activities to predict what to expect from their volunteers and plan the volunteer recruitment and retention processes during crises. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
49. Remaining Agile in the COVID-19 pandemic healthcare landscape – How we adopted a hybrid telemedicine Geriatric Oncology care model in an academic tertiary cancer center.
- Author
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Chen, Matthew, Mohd Said, Noorhanah, Mohd Rais, Nydia Camelia, Ho, Francis, Ling, Natalie, Chun, Meiling, Ng, Yean Shin, Eng, Wan Nghee, Yao, Yao, Korc-Grodzicki, Beatriz, and Pang, Angela
- Abstract
The COVID-19 pandemic has impacted healthcare on an unprecedented scale, with healthcare resources being channeled into managing the devastating effects of the outbreak. Healthcare provision for vulnerable older adults has also been affected by lockdowns and suspension of selected medical services worldwide. In our tertiary cancer center, the National University Cancer Institute, Singapore (NCIS), our Geriatric Oncology (GO) service for older adults with cancer was halted for five months. In this paper, we describe the adoption of a hybrid telemedicine model by our GO service to continue care provision for older adults in the midst of the pandemic. Comprehensive geriatric assessments (CGA) were done via telemedicine and virtual multidisciplinary discussions were held prior to the patients' clinic visits. A hybrid telemedicine consultation allowed geriatricians and oncologists, segregated in different sites during the pandemic, to provide a hybrid physical and video geriatric oncology consultation. Scheduled phone follow ups by GO nurses helped to monitor patients for treatment-related toxicities and geriatric syndromes. Two hundred fifty patients were enrolled in the program from July 2020 to August 2021. All were assessed with a CGA, with 240 receiving interventions in the one-stop clinic. The average amount of time spent per visit was shortened from four hours to two and a half hours with an average of three interventions on the same day, versus one previously. Of the patients who received interventions, 84.8% were satisfied with the hybrid telemedicine model and 80.8% of them had reported a maintained or improved quality of life after being enrolled in the program. Telemedicine has been widely adopted during the pandemic, but older adults with limited digital literacy may find it a challenge. Our hybrid telemedicine model has allowed us to continue to provide cancer care, identify issues brought about by social isolation, and render timely assistance. It has become imperative to adapt, prepare and plan for the challenges we may face amid the ongoing COVID-19 pandemic and similar future outbreaks. Only by doing so can we remain agile and resilient, to continue providing quality care to our older patients with cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
50. The impact of covid-19 on the regulation of nursing practice and education.
- Author
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Smith, Sherrill J. and Farra, Sharon L.
- Abstract
• What is currently known? Associate degree nursing programs must understand the regulation of nursing practice and education to support nursing workforce needs. • What the paper adds to existing knowledge: Most states have enacted changes to the regulation of practice and education in response to the COVID-19 pandemic. • How is the applied to practice? Associate degree nurse educators must continue to stay abreast of regulatory changes to support preparation of new nurse graduates who are ready to meet workforce needs to practice safely in today's healthcare environment. To adapt to the environment resulting from a worldwide pandemic, states across the country enacted regulation changes impacting nursing education, entry into practice, and licensure. In this manuscript, the authors collected state board of nursing data from sources including websites and letters from the State Boards to deans, directors, and chairs. Information obtained reflected changes to regulation of practice and regulation of education. As the pandemic continues, associate degree educators will need to continue to stay abreast of nursing regulation changes made to meet healthcare workforce needs while also ensuring public safety. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
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