1. Miniature Untethered EEG Recorder Improves Advanced Neuroscience Methodologies.
- Author
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Crispin-Bailey, Christopher, Austin, Jim, Platt, Bettina, Moulds, Anthony, and Crouch, Barry
- Abstract
Rodent electroencephalography (EEG) in preclinical research is frequently conducted in behaving animals. However, the difficulty inherent in identifying EEG epochs associated with a particular behavior or cue is a significant obstacle to more efficient analysis. In this paper we highlight a new solution, using infrared event stamping to accurately synchronize EEG, recorded from superficial sites above the hippocampus and prefrontal cortex, with video motion tracking data in a transgenic Alzheimer's disease (AD) mouse model. Epochs capturing specific behaviors were automatically identified and extracted prior to further analysis. This was achieved by the novel design of an ultra-miniature wearable EEG recorder, the NAT-1 device, and its in-situ IR recording module. The device is described in detail, and its contribution to enabling new neuroscience is demonstrated. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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