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The incidence of vascular injuries during cholecystectomy is reported as 0-2% in different series. The liver bed is a potential area that some serious bleeding can occur. It is well-known that middle hepatic vein is very close to gallbladder. It can be injured specially in patients with acute or chronic cholecystitis. We presented two patients, in which middle hepatic vein was detected very near to gallbladder during laparoscopic cholecystectomy. Two operations were done without any bleeding complication. [ABSTRACT FROM AUTHOR]