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Objective: Skin diseases constitute a widespread health concern, and the application of machine learning and deep learning algorithms has been instrumental in improving diagnostic accuracy and treatment effectiveness. This paper aims to provide a comprehensive review of the existing research on the utilization of machine learning and deep learning in the field of skin disease diagnosis, with a particular focus on recent widely used methods of deep learning. The present challenges and constraints were also analyzed and possible solutions were proposed. Methods: We collected comprehensive works from the literature, sourced from distinguished databases including IEEE, Springer, Web of Science, and PubMed, with a particular emphasis on the most recent 5-year advancements. From the extensive corpus of available research, twenty-nine articles relevant to the segmentation of dermatological images and forty-five articles about the classification of dermatological images were incorporated into this review. These articles were systematically categorized into two classes based on the computational algorithms utilized: traditional machine learning algorithms and deep learning algorithms. An in-depth comparative analysis was carried out, based on the employed methodologies and their corresponding outcomes. Conclusions: Present outcomes of research highlight the enhanced effectiveness of deep learning methods over traditional machine learning techniques in the field of dermatological diagnosis. Nevertheless, there remains significant scope for improvement, especially in improving the accuracy of algorithms. The challenges associated with the availability of diverse datasets, the generalizability of segmentation and classification models, and the interpretability of models also continue to be pressing issues. Moreover, the focus of future research should be appropriately shifted. A significant amount of existing research is primarily focused on melanoma, and consequently there is a need to broaden the field of pigmented dermatology research in the future. These insights not only emphasize the potential of deep learning in dermatological diagnosis but also highlight directions that should be focused on. [ABSTRACT FROM AUTHOR]

Simple Summary: The amount of diagnosed thyroid nodules increases every year. Many researchers have tried to optimize the process of classifying and diagnosing thyroid nodules using artificial intelligence. The aim of this study was to assess the latest applications of artificial intelligence in diagnosing and classifying thyroid nodules. The focus was on innovations in the use of artificial intelligence in the field of ultrasonography and microscopic diagnosis, although other applications were reviewed as well. In total, we analyzed 930 papers published from 2018 to 2022. The incidence of thyroid nodules diagnosed is increasing every year, leading to a greater risk of unnecessary procedures being performed or wrong diagnoses being made. In our paper, we present the latest knowledge on the use of artificial intelligence in diagnosing and classifying thyroid nodules. We particularly focus on the usefulness of artificial intelligence in ultrasonography for the diagnosis and characterization of pathology, as these are the two most developed fields. In our search of the latest innovations, we reviewed only the latest publications of specific types published from 2018 to 2022. We analyzed 930 papers in total, from which we selected 33 that were the most relevant to the topic of our work. In conclusion, there is great scope for the use of artificial intelligence in future thyroid nodule classification and diagnosis. In addition to the most typical uses of artificial intelligence in cancer differentiation, we identified several other novel applications of artificial intelligence during our review. [ABSTRACT FROM AUTHOR]

The world's population is increasing and so is the challenge on existing healthcare infrastructure to cope with the growing demand in medical diagnosis and evaluation. Although human experts are primarily tasked with the diagnosis of different medical conditions, artificial intelligence (AI)-assisted diagnoses have become considerably useful in recent times. One of the critical lung infections, which requires early diagnosis and subsequent treatment to reduce the mortality rate, is pneumonia. There are different methods for obtaining a pneumonia diagnosis; however, the adoption of chest X-rays is popular since it is non-invasive. The AI systems for a pneumonia diagnosis using chest X-rays are often built on supervised machine-learning (ML) models, which require labeled datasets for development. However, collecting labeled datasets is sometimes infeasible due to constraints such as human resources, cost, and time. As such, the problem that we address in this paper is the unsupervised classification of pneumonia using unsupervised ML models including the beta-variational convolutional autoencoder (β-VCAE) and other variants, such as convolutional autoencoders (CAE), denoising convolutional autoencoders (DCAE), and sparse convolutional autoencoders (SCAE). Namely, the pneumonia classification problem is cast into an anomaly detection to develop the aforementioned ML models. The experimental results show that pneumonia can be diagnosed with high recall, precision, f1-score, and f2-score using the proposed unsupervised models. In addition, we observe that the proposed models are competitive with the state-of-the-art models, which are trained on a labeled dataset. [ABSTRACT FROM AUTHOR]

Breast cancer is one of the most prevalent cancers among women worldwide, and early detection of the disease can be lifesaving. Detecting breast cancer early allows for treatment to begin faster, increasing the chances of a successful outcome. Machine learning helps in the early detection of breast cancer even in places where there is no access to a specialist doctor. The rapid advancement of machine learning, and particularly deep learning, leads to an increase in the medical imaging community's interest in applying these techniques to improve the accuracy of cancer screening. Most of the data related to diseases is scarce. On the other hand, deep-learning models need much data to learn well. For this reason, the existing deep-learning models on medical images cannot work as well as other images. To overcome this limitation and improve breast cancer classification detection, inspired by two state-of-the-art deep networks, GoogLeNet and residual block, and developing several new features, this paper proposes a new deep model to classify breast cancer. Utilizing adopted granular computing, shortcut connection, two learnable activation functions instead of traditional activation functions, and an attention mechanism is expected to improve the accuracy of diagnosis and consequently decrease the load on doctors. Granular computing can improve diagnosis accuracy by capturing more detailed and fine-grained information about cancer images. The proposed model's superiority is demonstrated by comparing it to several state-of-the-art deep models and existing works using two case studies. The proposed model achieved an accuracy of 93% and 95% on ultrasound images and breast histopathology images, respectively. [ABSTRACT FROM AUTHOR]

Diabetic foot is one of the main complications observed in diabetic patients; it is associated with the development of foot ulcers and can lead to amputation. In order to diagnose these complications, specialists have to analyze several factors. To aid their decisions and help prevent mistakes, the resort to computer-assisted diagnostic systems using artificial intelligence techniques is gradually increasing. In this paper, two different models for the classification of thermograms of the feet of diabetic and healthy individuals are proposed and compared. In order to detect and classify abnormal changes in the plantar temperature, machine learning algorithms are used in both models. In the first model, the foot thermograms are classified into four classes: healthy and three categories for diabetics. The second model has two stages: in the first stage, the foot is classified as belonging to a diabetic or healthy individual, while, in the second stage, a classification refinement is conducted, classifying diabetic foot into three classes of progressive severity. The results show that both proposed models proved to be efficient, allowing us to classify a foot thermogram as belonging to a healthy or diabetic individual, with the diabetic ones divided into three classes; however, when compared, Model 2 outperforms Model 1 and allows for a better performance classification concerning the healthy category and the first class of diabetic individuals. These results demonstrate that the proposed methodology can be a tool to aid medical diagnosis. [ABSTRACT FROM AUTHOR]

This study proposes a Computer-Aided Diagnostic (CAD) system to diagnose subjects with autism spectrum disorder (ASD). The CAD system identifies morphological anomalies within the brain regions of ASD subjects. Cortical features are scored according to their contribution in diagnosing a subject to be ASD or typically developed (TD) based on a trained machine-learning (ML) model. This approach opens the hope for developing a new CAD system for early personalized diagnosis of ASD. We propose a framework to extract the cerebral cortex from structural MRI as well as identifying the altered areas in the cerebral cortex. This framework consists of the following five main steps: (i) extraction of cerebral cortex from structural MRI; (ii) cortical parcellation to a standard atlas; (iii) identifying ASD associated cortical markers; (iv) adjusting feature values according to sex and age; (v) building tailored neuro-atlases to identify ASD; and (vi) artificial neural networks (NN) are trained to classify ASD. The system is tested on the Autism Brain Imaging Data Exchange (ABIDE I) sites achieving an average balanced accuracy score of 97 ± 2 % . This paper demonstrates the ability to develop an objective CAD system using structure MRI and tailored neuro-atlases describing specific developmental patterns of the brain in autism. [ABSTRACT FROM AUTHOR]

Syncope is a medical condition resulting in the spontaneous transient loss of consciousness and postural tone with spontaneous recovery. The diagnosis of syncope is a challenging task, as similar types of symptoms are observed in seizures, vertigo, stroke, coma, etc. The advent of Healthcare 4.0, which facilitates the usage of artificial intelligence and big data, has been widely used for diagnosing various diseases based on past historical data. In this paper, classification-based machine learning is used to diagnose syncope based on data collected through a head-up tilt test carried out in a purely clinical setting. This work is concerned with the use of classification techniques for diagnosing neurally mediated syncope triggered by a number of neurocardiogenic or cardiac-related factors. Experimental results show the effectiveness of using classification-based machine learning techniques for an early diagnosis and proactive treatment of neurally mediated syncope. [ABSTRACT FROM AUTHOR]

The classification and recognition of foliar diseases is an increasingly developing field of research, where the concepts of machine and deep learning are used to support agricultural stakeholders. Datasets are the fuel for the development of these technologies. In this paper, we release and make publicly available the field dataset collected to diagnose and monitor plant symptoms, called DiaMOS Plant, consisting of 3505 images of pear fruit and leaves affected by four diseases. In addition, we perform a comparative analysis of existing literature datasets designed for the classification and recognition of leaf diseases, highlighting the main features that maximize the value and information content of the collected data. This study provides guidelines that will be useful to the research community in the context of the selection and construction of datasets. [ABSTRACT FROM AUTHOR]

Exhaled breath analysis has become more and more popular as a supplementary tool for medical diagnosis. However, the number of variables that have to be taken into account forces researchers to develop novel algorithms for proper data interpretation. This paper presents a system for analyzing exhaled air with the use of various sensors. Breath simulations with acetone as a diabetes biomarker were performed using the proposed e-nose system. The XGBoost algorithm for diabetes detection based on artificial breath analysis is presented. The results have shown that the designed system based on the XGBoost algorithm is highly selective for acetone, even at low concentrations. Moreover, in comparison with other commonly used algorithms, it was shown that XGBoost exhibits the highest performance and recall. [ABSTRACT FROM AUTHOR]