1. 1,8-Cineole: a review of source, biological activities, and application.
- Author
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Cai, Zi-Min, Peng, Jian-Qing, Chen, Yi, Tao, Ling, Zhang, Yan-Yan, Fu, Ling-Yun, Long, Qing-De, and Shen, Xiang-Chun
- Subjects
DRUG administration routes ,TERPENES ,MEDICINAL plants ,ESSENTIAL oils ,ALZHEIMER'S disease ,ANTI-inflammatory agents ,BIOAVAILABILITY ,ANTIOXIDANTS ,CARDIOVASCULAR diseases ,ANTINEOPLASTIC agents ,EUCALYPTUS oil ,DNA-binding proteins ,PLANT extracts ,RESPIRATORY distress syndrome ,PHARMACEUTICAL chemistry ,ROSEMARY - Abstract
1,8-Cineole (also known as eucalyptol) is mostly extracted from the essential oils of plants, which showed extensively pharmacological properties including anti-inflammatory and antioxidant mainly via the regulation on NF-κB and Nrf2, and was used for the treatment of respiratory diseases and cardiovascular, etc. Although various administration routes have been used in the application of 1.8-cineole, few formulations have been developed to improve its stability and bioavailability. This review retrospects the researches on the source, biological activities, mechanisms, and application of 1,8-cineole since 2000, which provides a view for the further studies on the application and formulations of 1,8-cineole. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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