1. Recent advances in entirely hand-held ionization sources for mass spectrometry.
- Author
-
Fan J, Ma W, Yu Y, Li Y, and Nie Z
- Subjects
- Mass Spectrometry methods, Atmospheric Pressure, Spectrometry, Mass, Electrospray Ionization methods
- Abstract
Ambient ionization mass spectrometry (AIMS) has been developing explosively since its first debut. The ionization process was hence able to be achieved under atmospheric pressure, facilitating on-site field analysis in a variety of areas, such as clinical diagnosis, metabolic phenotyping, and surface analysis. As part of the ambitious goal of making MS a general device that can be used in everyday life, lots of efforts have been paid to miniaturize the ionization source. This review discusses avant-garde sources that could be entirely hand-held without any accessories. The structure and applications of the devices are described in detail as well. They could be expediently used in real-time and on-site analysis, presenting a great future potential for the routinizing of MS., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.)
- Published
- 2024
- Full Text
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