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COVID-19 cases are still rising globally in the middle of the tuberculosis epidemic. Several countries have reported TB-COVID-19 coinfection that could pose a double burden in the health care facilities in developing countries. We reported two pulmonary tuberculosis patients coinfected with COVID-19 with an overlapping clinical manifestation of tuberculosis and COVID-19 with a good prognosis at the end of COVID-19 treatment. This paper aims to discuss TB patients' susceptibility against SARS-COV-2 infection, the clinical profile of TB-COVID-19 coinfection, and the disease's prognosis. The clinician should be aware of both common disease symptoms that appear in a patient and should be confirmed and treat promptly. [ABSTRACT FROM AUTHOR]

This paper presents a study of early epidemiological assessment of COVID-19 transmission dynamics in Indonesia. The aim is to quantify heterogeneity in the numbers of secondary infections. To this end, we estimate the basic reproduction number R 0 and the overdispersion parameter K at two regions in Indonesia: Jakarta–Depok and Batam. The method to estimate R 0 is based on a sequential Bayesian method, while the parameter K is estimated by fitting the secondary case data with a negative binomial distribution. Based on the first 1288 confirmed cases collected from both regions, we find a high degree of individual-level variation in the transmission. The basic reproduction number R 0 is estimated at 6.79 and 2.47, while the overdispersion parameter K of a negative-binomial distribution is estimated at 0.06 and 0.2 for Jakarta–Depok and Batam, respectively. This suggests that superspreading events played a key role in the early stage of the outbreak, i.e., a small number of infected individuals are responsible for large numbers of COVID-19 transmission. This finding can be used to determine effective public measures, such as rapid isolation and identification, which are critical since delay of diagnosis is the most common cause of superspreading events. [ABSTRACT FROM AUTHOR]