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This paper presents an in-depth analysis of an excitable membrane of a biological system by proposing a novel approach that the cells of the excitable membrane can be modeled as the networks of memristors. We provide compelling evidence from the Chay neuron model that the state-independent mixed ion channel is a nonlinear resistor, while the state-dependent voltage-sensitive potassium ion channel and calcium-sensitive potassium ion channel function as generic memristors from the perspective of electrical circuit theory. The mechanisms that give rise to periodic oscillation, aperiodic (chaotic) oscillation, spikes, and bursting in an excitable cell are also analyzed via a small-signal model, a pole-zero diagram of admittance functions, local activity, the edge of chaos, and the Hopf bifurcation theorem. It is also proved that the zeros of the admittance functions are equivalent to the eigen values of the Jacobian matrix, and the presence of the positive real parts of the eigen values between the two bifurcation points lead to the generation of complicated electrical signals in an excitable membrane. The innovative concepts outlined in this paper pave the way for a deeper understanding of the dynamic behavior of excitable cells, offering potent tools for simulating and exploring the fundamental characteristics of biological neurons. [ABSTRACT FROM AUTHOR]

In this paper, we consider the influence of a nonlinear contact rate caused by multiple contacts in classical SIR model. In this paper, we unversal unfolding a nilpotent cusp singularity in such systems through normal form theory, we reveal that the system undergoes a Bogdanov-Takens bifurcation with codimension 2. During the bifurcation process, numerous lower codimension bifurcations may emerge simultaneously, such as saddle-node and Hopf bifurcations with codimension 1. Finally, employing the Matcont and Phase Plane software, we construct bifurcation diagrams and topological phase portraits. Additionally, we emphasize the role of symmetry in our analysis. By considering the inherent symmetries in the system, we provide a more comprehensive understanding of the dynamical behavior. Our findings suggest that if this occurrence rate is applied to the SIR model, it would yield different dynamical phenomena compared to those obtained by reducing a 3-dimensional dynamical model to a planar system by neglecting the disease mortality rate, which results in a stable nilpotent cusp singularity with codimension 2. We found that in SIR models with the same occurrence rate, both stable and unstable Bogdanov-Takens bifurcations occur, meaning both stable and unstable limit cycles appear in this system. [ABSTRACT FROM AUTHOR]

Understand the dynamics of cancer stem cells (CSCs), prevent the non-recurrence of cancers and develop therapeutic strategies to destroy both cancer cells and CSCs remain a challenge topic. In this paper, we study both analytically and numerically the dynamics of CSCs under radiotherapy effects. The dynamical model takes into account the diffusion of cells, the de-differentiation (or plasticity) mechanism of differentiated cancer cells (DCs) and the time delay on the interaction between microRNAs molecules (microRNAs) with DCs. The stability of the model system is studied by using a Hopf bifurcation analysis. We mainly investigate on the critical time delay τ c , that represents the time for DCs to transform into CSCs after the interaction of microRNAs with DCs. Using the system parameters, we calculate the value of τ c for prostate, lung and breast cancers. To confirm the analytical predictions, the numerical simulations are performed and show the formation of spatiotemporal circular patterns. Such patterns have been found as promising diagnostic and therapeutic value in management of cancer and various diseases. The radiotherapy is applied in the particular case of prostate model. We calculate the optimum dose of radiation and determine the probability of avoiding local cancer recurrence after radiotherapy treatment. We find numerically a complete eradication of patterns when the radiotherapy is applied before a time t < τ c . This scenario induces microRNAs to act as suppressors as experimentally observed in prostate cancer. The results obtained in this paper will provide a better concept for the clinicians and oncologists to understand the complex dynamics of CSCs and to design more efficacious therapeutic strategies to prevent the non-recurrence of cancers. [ABSTRACT FROM AUTHOR]

In this paper, to investigate the dynamic interplay between supply and demand, with a focus on collectability, a novel mathematical model was introduced via conformable operator. This model considers the possibility that operating expenses or a lack of raw materials causes a manufacturing delay than the supply of goods instantly matching demand. This maturation (delay) is represented by the delay factor (τ) . Stability analysis revolves around the equilibrium point other than zero. Chaotic behavior emerges through Hopf bifurcation at the critical delay parameter value. If this delay parameter is even slightly perturbed, oscillatory limit cycles can be induced in the market dynamics, leading to equilibrium with brisk market expansion, frequent recessions, and sudden collapses. We conducted sensitivity and directional analysis on a number of factors while also examining the stability and duration of the Hopf bifurcation. Numerical findings were validated using MATLAB. Additionally, the Caputo operator was used to examine the fractional of demand and supply dynamics. Importantly, we assumed a pivotal role in advancing fair labor practices and fostering economic growth on a national scale. In this paper, to investigate the dynamic interplay between supply and demand, with a focus on collectability, a novel mathematical model was introduced via conformable operator. This model considers the possibility that operating expenses or a lack of raw materials causes a manufacturing delay than the supply of goods instantly matching demand. This maturation (delay) is represented by the delay factor . Stability analysis revolves around the equilibrium point other than zero. Chaotic behavior emerges through Hopf bifurcation at the critical delay parameter value. If this delay parameter is even slightly perturbed, oscillatory limit cycles can be induced in the market dynamics, leading to equilibrium with brisk market expansion, frequent recessions, and sudden collapses. We conducted sensitivity and directional analysis on a number of factors while also examining the stability and duration of the Hopf bifurcation. Numerical findings were validated using MATLAB. Additionally, the Caputo operator was used to examine the fractional of demand and supply dynamics. Importantly, we assumed a pivotal role in advancing fair labor practices and fostering economic growth on a national scale. [ABSTRACT FROM AUTHOR]

This paper outlines a methodology for the construction of vector fields that can enable a multi-robot system moving on the plane to generate multiple dynamical behaviors by adjusting a single scalar parameter. This parameter essentially triggers a Hopf bifurcation in an underlying time-varying dynamical system that steers a robotic swarm. This way, the swarm can exhibit a variety of behaviors that arise from the same set of continuous differential equations. Other approaches to bifurcation-based swarm coordination rely on agent interaction which cannot be realized if the swarm members cannot sense or communicate with one another. The contribution of this paper is to offer an alternative method for steering minimally instrumented multi-robot collectives with a control strategy that can realize a multitude of dynamical behaviors without switching their constituent equations. Through this approach, analytical solutions for the bifurcation parameter are provided, even for more complex cases that are described in the literature, along with the process to apply this theory in a multi-agent setup. The theoretical predictions are confirmed via simulation and experimental results with the latter also demonstrating real-world applicability. [ABSTRACT FROM AUTHOR]

With the frequent occurrence of financial risks, financial innovation supervision has become an important research issue, and excellent regulatory strategies are of great significance to maintain the stability and sustainable development of financial markets. Thus, this paper intends to analyze the financial regulation strategies through evolutionary game theory. In this paper, the delayed replication dynamic equation and the non-delayed replication dynamic equation are established, respectively, under different reward and punishment mechanisms, and their stability conditions and evolutionary stability strategies are investigated. The analysis finds that under the static mechanism, the internal equilibrium is unstable, and the delay does not affect the stability of the system, while in the dynamic mechanism, when the delay is less than a critical value, the two sides of the game have an evolutionary stable strategy, otherwise it is unstable, and Hopf bifurcation occurs at threshold. Finally, some numerical simulation examples are provided, and the numerical results show the correctness of the proposed algorithm. [ABSTRACT FROM AUTHOR]

We are concerned in this paper with the stability and bifurcation problems for three-neuron-based bi-directional associative memory neural networks that are involved with time delays in transmission terms and possess Caputo fractional derivatives of non-commensurate orders. For the fractional bi-directional associative memory neural networks that are dealt with in this paper, we view the time delays as the bifurcation parameters. Via a standard contraction mapping argument, we establish the existence and uniqueness of the state trajectories of the investigated fractional bi-directional associative memory neural networks. By utilizing the idea and technique of linearization, we analyze the influence of time delays on the dynamical behavior of the investigated neural networks, as well as establish and prove several stability/bifurcation criteria for the neural networks dealt with in this paper. According to each of our established criteria, the equilibrium states of the investigated fractional bi-directional associative memory neural networks are asymptotically stable when some of the time delays are less than strictly specific positive constants, i.e., when the thresholds or the bifurcation points undergo Hopf bifurcation in the concerned networks at the aforementioned threshold constants. In the meantime, we provide several illustrative examples to numerically and visually validate our stability and bifurcation results. Our stability and bifurcation theoretical results in this paper yield some insights into the cause mechanism of the bifurcation phenomena for some other complex phenomena, and this is extremely helpful for the design of feedback control to attenuate or even to remove such complex phenomena in the dynamics of fractional bi-directional associative memory neural networks with time delays. [ABSTRACT FROM AUTHOR]

The subject of this paper concerns with the bifurcation of limit cycles for a predator-prey model with small immigration. Since, in general, the biological systems are not isolated, taking into account immigration in the model becomes more realistic. In this context, we deal with a model with a Holling type Ⅰ function response and study, using averaging theory of second order, the Hopf bifurcation that can emerge under small perturbation of the biological parameters. [ABSTRACT FROM AUTHOR]

In this paper, by replacing the exponential memory kernel function of a tabu learning single-neuron model with the power-law memory kernel function, a novel Caputo's fractional-order tabu learning single-neuron model and a network of two interacting fractional-order tabu learning neurons are constructed firstly. Different from the integer-order tabu learning model, the order of the fractional-order derivative is used to measure the neuron's memory decay rate and then the stabilities of the models are evaluated by the eigenvalues of the Jacobian matrix at the equilibrium point of the fractional-order models. By choosing the memory decay rate (or the order of the fractional-order derivative) as the bifurcation parameter, it is proved that Hopf bifurcation occurs in the fractional-order tabu learning single-neuron model where the value of bifurcation point in the fractional-order model is smaller than the integer-order model's. By numerical simulations, it is shown that the fractional-order network with a lower memory decay rate is capable of producing tangent bifurcation as the learning rate increases from 0 to 0.4. When the learning rate is fixed and the memory decay increases, the fractional-order network enters into frequency synchronization firstly and then enters into amplitude synchronization. During the synchronization process, the oscillation frequency of the fractional-order tabu learning two-neuron network increases with an increase in the memory decay rate. This implies that the higher the memory decay rate of neurons, the higher the learning frequency will be. [ABSTRACT FROM AUTHOR]

In this paper, we investigate a Leslie-type predator-prey model that incorporates prey harvesting and group defense, leading to a modified functional response. Our analysis focuses on the existence and stability of the system's equilibria, which are essential for the coexistence of predator and prey populations and the maintenance of ecological balance. We identify the maximum sustainable yield, a critical factor for achieving this balance. Through a thorough examination of positive equilibrium stability, we determine the conditions and initial values that promote the survival of both species. We delve into the system's dynamics by analyzing saddle-node and Hopf bifurcations, which are crucial for understanding the system transitions between various states. To evaluate the stability of the Hopf bifurcation, we calculate the first Lyapunov exponent and offer a quantitative assessment of the system's stability. Furthermore, we explore the Bogdanov-Takens (BT) bifurcation, a co-dimension 2 scenario, by employing a universal unfolding technique near the cusp point. This method simplifies the complex dynamics and reveals the conditions that trigger such bifurcations. To substantiate our theoretical findings, we conduct numerical simulations, which serve as a practical validation of the model predictions. These simulations not only confirm the theoretical results but also showcase the potential of the model for predicting real-world ecological scenarios. This in-depth analysis contributes to a nuanced understanding of the dynamics within predator-prey interactions and advances the field of ecological modeling. [ABSTRACT FROM AUTHOR]

In this paper, a delay differential equation model is investigated, which describes the biodegradation of microcystins (MCs) by Sphingomonas sp. and its degrading enzymes. First, the local stability of the positive equilibrium and the existence of the Hopf bifurcation are obtained. Second, the global attractivity of the positive equilibrium is obtained by constructing suitable Lyapunov functionals, which implies that the biodegradation of microcystins is sustainable under appropriate conditions. In addition, some numerical simulations of the model are carried out to illustrate the theoretical results. Finally, the parameters of the model are determined from the experimental data and fitted to the data. The results show that the trajectories of the model fit well with the trend of the experimental data. [ABSTRACT FROM AUTHOR]

Due to factors such as climate change, natural disasters, and deforestation, most measurement processes and initial data may have errors. Therefore, models with imprecise parameters are more realistic. This paper constructed a new predator-prey model with an interval biological coefficient by using the interval number as the model parameter. First, the stability of the solution of the fractional order model without a diffusion term and the Hopf bifurcation of the fractional order α were analyzed theoretically. Then, taking the diffusion coefficient of prey as the key parameter, the Turing stability at the equilibrium point was discussed. The amplitude equation near the threshold of the Turing instability was given by using the weak nonlinear analysis method, and different mode selections were classified by using the amplitude equation. Finally, we numerically proved that the dispersal rate of the prey population suppressed the spatiotemporal chaos of the model. [ABSTRACT FROM AUTHOR]

In this paper, the impact of the strong Allee effect and ratio-dependent Holling–Tanner functional response on the dynamical behaviors of a predator–prey system is investigated. First, the positivity and boundedness of solutions of the system are proved. Then, stability and bifurcation analysis on equilibria is provided, with explicit conditions obtained for Hopf bifurcation. Moreover, global dynamics of the system is discussed. In particular, the degenerate singular point at the origin is proved to be globally asymptotically stable under various conditions. Further, a detailed bifurcation analysis is presented to show that the system undergoes a codimension- 1 Hopf bifurcation and a codimension- 2 cusp Bogdanov–Takens bifurcation. Simulations are given to illustrate the theoretical predictions. The results obtained in this paper indicate that the strong Allee effect and proportional dependence coefficient have significant impact on the fundamental change of predator–prey dynamics and the species persistence. [ABSTRACT FROM AUTHOR]

In this paper, we analyze the strong feedback limit of two negative feedback schemes which have proven to be efficient for many biological processes (protein synthesis, immune responses, breathing disorders). In this limit, the nonlinear delayed feedback function can be reduced to a function with a threshold nonlinearity. This will considerably help analytical and numerical studies of networks exhibiting different topologies. Mathematically, we compare the bifurcation diagrams for both the delayed and non-delayed feedback functions and show that Hopf classical theory needs to be revisited in the strong feedback limit. [ABSTRACT FROM AUTHOR]

In this paper, we study a class of compatimental epidemiological models consisting of Susceptible, Infected, and Removed (SIR) individuals with a perturbation factor or exterior effects such as noise, climate change, pollution, etc. We prove the existence and uniqueness of a limit cycle confined in a nonempty closed and convex set by relying on a recent result of Lobanova and Sadovskii. Moreover, we study the existence of Hopf and Bogdanov-Takens bifurcations by applying respectively Poincare-Andronov-Hopf bifurcation theorem and Bogdanov-Takens theorem. Eventually, using Scilab, we illustrate the validity of our results with numerical simulations and also interpret them. [ABSTRACT FROM AUTHOR]

This paper studies the dynamics of interacting Tilapia fish and Pelican bird population in the Salton Sea. We assume that the diseases spread in Tilapia fish follows the Holling type II response function, and the interaction between Tilapia and Pelican follows the Beddington–DeAngelis response function. The dynamics of diffusive and delayed system are discussed separately. Analytically, all the feasible equilibria and their stability are discussed. The criterion for Turing instability is derived. Based on the normal form theory and center manifold arguments, the existence of stability criterion and the direction of Hopf bifurcation are obtained. Numerical simulation shows the occurrence Hopf bifurcation, double Hopf bifurcation and transcritical bifurcation scenarios. The snap shot shows the spot, spot-strip mix patterns in the whole domain. Further, the stability switching phenomena is observed in the delayed system. Our comprehensive study highlights the effect of different parameters, multiple time delay and extinction in Pelican populations. [ABSTRACT FROM AUTHOR]

In this paper, a fractional-order two delays neural network with ring-hub structure is investigated. Firstly, the stability and the existence of Hopf bifurcation of proposed system are obtained by taking the sum of two delays as the bifurcation parameter. Furthermore, a parameters delay feedback controller is introduced to control successfully Hopf bifurcation. The novelty of this paper is that the characteristic equation corresponding to system has two time delays and the parameters depend on one of them. Selecting two time delays as the bifurcation parameters simultaneously, stability switching curves in (τ 1 , τ 2) plane and crossing direction are obtained. Sufficient criteria for the stability and the existence of Hopf bifurcation of controlled system are given. Ultimately, numerical simulation shows that parameters delay feedback controller can effectively control Hopf bifurcation of system. [ABSTRACT FROM AUTHOR]

The paper's primary objective is to examine the dynamic behavior of an integer and noninteger predator–prey system with a Holling type IV functional response in the Caputo sense. Our focus is on understanding how harvesting influences the stability, equilibria, bifurcations, and limit cycles within this system. We employ qualitative and quantitative analysis methods rooted in bifurcation theory, dynamical theory, and numerical simulation. We also delve into studying the boundedness of solutions and investigating the stability and existence of equilibrium points within the system. Leveraging Sotomayor's theorem, we establish the presence of both the saddle-node and transcritical bifurcations. The analysis of the Hopf bifurcation is carried out using the normal form theorem. The model under consideration is extended to the fractional reaction–diffusion model which captures non-local and long-range effects more accurately than integer-order derivatives. This makes fractional reaction–diffusion systems suitable for modeling phenomena with anomalous diffusion or memory effects, improving the fidelity of simulations in turn. An adaptable numerical technique for solving this class of differential equations is also suggested. Through simulation results, we observe that one of the Lyapunov exponents has a negative value, indicating the potential for the emergence of a stable-limit cycle via bifurcation as well as chaotic and complex spatiotemporal distributions. We supplement our analytical investigations with numerical simulations to provide a comprehensive understanding of the system's behavior. It was discovered that both the prey and predator populations will continue to coexist and be permanent, regardless of the choice of fractional parameter. [ABSTRACT FROM AUTHOR]

In this paper, a class of two-delay differential equations with coefficient-dependent delay is studied. The distribution of the roots of the eigenequation is discussed, and conditions for the stability of the internal equilibrium and the existence of Hopf bifurcation are obtained. Additionally, using the normal form method and the central manifold theory, the bifurcation direction and the stability for the periodic solution of Hopf bifurcation are calculated. Finally, the correctness of the theory is verified by numerical simulation. [ABSTRACT FROM AUTHOR]

The coronavirus disease 2019 (COVID-19) remains serious around the world and causes huge deaths and economic losses. Understanding the transmission dynamics of diseases and providing effective control strategies play important roles in the prevention of epidemic diseases. In this paper, to investigate the effect of delays on the transmission of COVID-19, we propose a delayed SEIR model to describe COVID-19 virus transmission, where two delays indicating the incubation and recovery periods are introduced. For this system, we prove its solutions are nonnegative and ultimately bounded with the nonnegative initial conditions. Furthermore, we calculate the disease-free and endemic equilibrium points and analyze the asymptotical stability and the existence of Hopf bifurcations at these equilibrium points. Then, by taking the weighted sum of the opposite number of recovered individuals at the terminal time, the number of exposed and infected individuals during the time horizon, and the system cost of control measures as the cost function, we present a delay optimal control problem, where two controls represent the social contact and the pharmaceutical intervention. Necessary optimality conditions of this optimal control problem are exploited to characterize the optimal control strategies. Finally, numerical simulations are performed to verify the theoretical analysis of the stability and Hopf bifurcations at the equilibrium points and to illustrate the effectiveness of the obtained optimal strategies in controlling the COVID-19 epidemic. [ABSTRACT FROM AUTHOR]

In recent years, one of the most prevalent matters in population ecology has been the study of predator-prey relationships. In this context, this paper investigated the dynamic behavior of a delayed predator-prey model considering square root type functional response and stage structure for predators. First, we obtained positivity and boundedness of the solutions and existence of equilibrium points. Second, by applying the stability theory of delay differential equations and the Hopf bifurcation theorem, we discussed the system's local stability and the existence of a Hopf bifurcation at the positive equilibrium point. Moreover, the properties of the Hopf bifurcation were deduced by using the central manifold theorem and normal form method. Analytical results showed that when the time delay was less than the critical value, the two populations will coexist, otherwise the ecological balance will be disrupted. Finally, some numerical simulations were also included to verify the theoretical results. [ABSTRACT FROM AUTHOR]

In order to stop and reverse land degradation and curb the loss of biodiversity, the United Nations 2030 Agenda for Sustainable Development proposes to combat desertification. In this paper, a fractional vegetation–water model in an arid flat environment is studied. The pattern behavior of the fractional model is much more complex than that of the integer order. We study the stability and Turing instability of the system, as well as the Hopf bifurcation of fractional order α , and obtain the Turing region in the parameter space. According to the amplitude equation, different types of stationary mode discoveries can be obtained, including point patterns and strip patterns. Finally, the results of the numerical simulation and theoretical analysis are consistent. We find some novel fractal patterns of the fractional vegetation–water model in an arid flat environment. When the diffusion coefficient, d, changes and other parameters remain unchanged, the pattern structure changes from stripes to spots. When the fractional order parameter, β , changes, and other parameters remain unchanged, the pattern structure becomes more stable and is not easy to destroy. The research results can provide new ideas for the prevention and control of desertification vegetation patterns. [ABSTRACT FROM AUTHOR]

In this paper, we carry out some research on a predator–prey system with maturation delay, a stage structure for generalist predators and a Holling type-II functional response, which has already been proposed. First, for the delayed model, we obtain the conditions for the occurrence of stability switches of the positive equilibrium and possible Hopf bifurcation values owing to the growth of the value of the delay by applying the geometric criterion. It should be pointed out that when we suppose that the characteristic equation has a pair of imaginary roots λ = ± i ω (ω > 0) , we just need to consider i ω (ω > 0) due to the symmetry, which alleviates the computation requirements. Next, we investigate the nature of Hopf bifurcation. Finally, we conduct numerical simulations to verify the correctness of our findings. [ABSTRACT FROM AUTHOR]

The protection of forests and the mitigation of pest damage to trees play a crucial role in mitigating the greenhouse effect. In this paper, we first establish a delayed differential equation model for Ips subelongatus Motschulsky-Larix spp., where the delay parameter represents the time required for trees to undergo curing. Second, we analyze the stability of the equilibrium of the model and derive the normal form of Hopf bifurcation using a multiple-time-scales method. Then, we analyze the stability and direction of Hopf bifurcating periodic solutions. Finally, we conduct simulations to analyze the changing trends in pest and tree populations. Additionally, we investigate the impact of altering the rate of artificial planting on the system and provide corresponding biological explanations. [ABSTRACT FROM AUTHOR]

In this paper, a generalized fractional three-species food chain model with delay is investigated. First, the existence of a positive equilibrium is discussed, and the sufficient conditions for global asymptotic stability are given. Second, through selecting the delay as the bifurcation parameter, we obtain the sufficient condition for this non-control system to generate Hopf bifurcation. Then, a nonlinear delayed feedback controller is skillfully applied to govern the system's Hopf bifurcation. The results indicate that adjusting the control intensity or the control target's age can effectively govern the bifurcation dynamics behavior of this system. Last, through application examples and numerical simulations, we confirm the validity and feasibility of the theoretical results, and find that the control strategy is also applicable to eco-epidemiological systems. [ABSTRACT FROM AUTHOR]

A double-time-delay Holling Ⅱ predator model with weak Allee effect and age structure was studied in this paper. First, the model was converted into an abstract Cauchy problem. We also discussed the well-posedness of the model and the existence of the equilibrium solution. We analyzed the global stability of boundary equilibrium points, the local stability of positive equilibrium points, and the conditions of the Hopf bifurcation for the system. The conclusion was verified by numerical simulation. [ABSTRACT FROM AUTHOR]

This paper investigates the problem of bifurcation analysis and bifurcation control of a fractional-order gene regulatory network with sRNA. Firstly, the process of stability change of system equilibrium under the influence of the sum of time delay is discussed, the critical condition of Hopf bifurcation is explored, and the effect of fractional order on the system stability domain. Secondly, aiming at the system's instability caused by a large time delay, we design a controller to improve the system's stability and derive the parameter conditions that satisfy the system's stability. It is found that changing the parameter values of the controller within a certain range can control the system's nonlinear behaviours and effectively expand the stability range. Then, a numerical example is given to illustrate the results of this paper. [ABSTRACT FROM AUTHOR]

In this paper, the stability and bifurcation of a two–dimensional p53 gene regulatory network without and with time delay are taken into account by rigorous theoretical analyses and numerical simulations. In the absence of time delay, the existence and local stability of the positive equilibrium are considered through the Descartes' rule of signs, the determinant and trace of the Jacobian matrix, respectively. Then, the conditions for the occurrence of codimension–1 saddle–node and Hopf bifurcation are obtained with the help of Sotomayor's theorem and the Hopf bifurcation theorem, respectively, and the stability of the limit cycle induced by hopf bifurcation is analyzed through the calculation of the first Lyapunov number. Furthermore, codimension-2 Bogdanov–Takens bifurcation is investigated by calculating a universal unfolding near the cusp. In the presence of time delay, we prove that time delay can destabilize a stable equilibrium. All theoretical analyses are supported by numerical simulations. These results will expand our understanding of the complex dynamics of p53 and provide several potential biological applications. [ABSTRACT FROM AUTHOR]

In this essay, we introduce a bioeconomic predator–prey model which incorporates the square root functional response and nonlinear prey harvesting. Due to the introduction of nonlinear prey harvesting, the model demonstrates intricate dynamic behaviors in the predator–prey plane. Economic profit serves as a bifurcation parameter for the system. The stability and Hopf bifurcation of the model are discussed through normal forms and bifurcation theory. These results reveal richer dynamic features of the bioeconomic predator–prey model which incorporates the square root functional response and nonlinear prey harvesting, and provides guidance for realistic harvesting. A feedback controller is introduced in this paper to move the system from instability to stability. Moreover, we discuss the biological implications and interpretations of the findings. Finally, the results are validated by numerical simulations. [ABSTRACT FROM AUTHOR]

Analysing the prey-predator model is the purpose of this paper. In interactions of the Beddington–DeAngelis type, the predator consumes its prey. Researchers first examine the existence and local stability of potential unbalanced equilibrium boundaries for the model. In addition, for the suggested model incorporating the prey refuge, we investigate the Hopf bifurcation inquiry. To emphasise our key analytical conclusions, we show some numerical simulation results at the end. [ABSTRACT FROM AUTHOR]

The study of harvesting mechanisms in predator-prey systems with an Allee effect on prey has always garnered significant attention. In this paper, the dynamics and harvesting strategies of a predator-prey system are investigated, where the prey is subject to the Allee effect. The positivity and boundedness of solutions, the existence and stability of equilibria are further studied. The existence of a Hopf bifurcation at the interior equilibrium point of the system is investigated and verified by numerical simulations. Furthermore, we investigate the maximum sustainable yield (MSY), maximum sustainable total yield (MSTY) and the optimal economic profit of the proposed system. We find that MSY can be attained through predator harvesting, while MSTY is observed when harvesting efforts are uniform across species. In these situations, the biological system maintains stability. Using the method of control parametrization, the optimal economic profit and harvesting strategy are obtained. The results show that the harvesting efforts can affect the stability of the system, resulting in several interesting biological phenomena. This research provides a theoretical basis for biological resource management. [ABSTRACT FROM AUTHOR]

In this paper, we introduce the Crowley–Martin functional response and nonlocal competition into a reaction–diffusion immunosuppressive infection model. First, we analyze the existence and stability of the positive constant steady states of the systems with nonlocal competition and local competition, respectively. Second, we deduce the conditions for the occurrence of Turing, Hopf, and Turing–Hopf bifurcations of the system with nonlocal competition, as well as the conditions for the occurrence of Hopf bifurcations of the system with local competition. Furthermore, we employ the multiple time scales method to derive the normal forms of the Hopf bifurcations reduced on the center manifold for both systems. Finally, we conduct numerical simulations for both systems under the same parameter settings, compare the impact of nonlocal competition, and find that the nonlocal term can induce spatially inhomogeneous stable periodic solutions. We also provide corresponding biological explanations for the simulation results. [ABSTRACT FROM AUTHOR]

In this paper, we investigate a reaction-diffusion model incorporating dynamic variables for nutrient, phytoplankton, and zooplankton. Moreover, we account for the impact of time delay in the growth of phytoplankton following nutrient uptake. Our theoretical analysis reveals that the time delay can trigger the emergence of persistent oscillations in the model via a Hopf bifurcation. We also analytically track the direction of Hopf bifurcation and the stability of the bifurcating periodic solutions. Our simulation results demonstrate stability switches occurring for the positive equilibrium with an increasing time lag. Furthermore, the model exhibits homogeneous periodic-2 and 3 solutions, as well as chaotic behaviour. These findings highlight that the presence of time delay in the phytoplankton growth can bring forth dynamical complexity to the nutrient-plankton system of aquatic habitats. [ABSTRACT FROM AUTHOR]

In this paper, we consider a delayed single population model with patch structure, and investigate Hopf bifurcations when the dispersal rate or the scaling parameter of the growth rate is small. The effect of dispersal patterns is analyzed. We show that dispersal patterns affect the occurrence of Hopf bifurcations when the scaling parameter of the growth rate is small, and affect the values of Hopf bifurcations when the dispersal rate is small. [ABSTRACT FROM AUTHOR]

In this paper, we investigate the spatiotemporal dynamics of the Sel'kov–Schnakenberg system. The stability of the positive constant steady state is studied by the linear stability theory. Hopf bifurcation and Turing–Hopf bifurcation are generated by varying two parameters in the model. The normal form near the Turing–Hopf singularity is calculated to explore the complex dynamics of the system. Finally, numerical simulations are carried out to verify the theoretical results. Our results show that the Sel'kov–Schnakenberg system exhibits complex dynamics near the Turing–Hopf singularity, including the existence of inhomogeneous steady states, homogeneous periodic solutions and inhomogeneous periodic solutions. [ABSTRACT FROM AUTHOR]

In this paper, a Leslie–Gower model with weak Allee effect on prey and fear effect on predator is proposed. Compared with the case without fear effect on predator, the new model undergoes richer dynamic behaviors such as saddle-node bifurcation, Hopf bifurcation and Bogdanov–Takens bifurcation. Also, different from the strong Allee effect on prey, the system with weak Allee effect has bistable attractors which are a largely stable limit cycle and a stable positive equilibrium, two stable equilibria, or a stable limit cycle and a stable trivial equilibrium. When the Allee effect coefficient is intermediate, fear effect on the predator can protect the prey and the predator from being extinguished. The results in this paper can be seen as a complement to those in the literatures about the Leslie–Gower model with Allee effect and fear effect. [ABSTRACT FROM AUTHOR]

This paper is concerned with a prey–predator system involving herd behaviour and strong Allee effect. First, the local stability analysis of all the possible equilibrium points are investigated. Second, the existence of Hopf bifurcation around the unique positive equilibrium are carried out. Finally, this paper is ended with a numerical simulation to understand the dynamics of the system. As it turns out that the 'Allee effect constant' plays a very important role in biological invasion mechanism, such as controlling and preventing biological invasion or invading successfully. [ABSTRACT FROM AUTHOR]

This paper will explore a fractional-order hepatitis B virus (HBV) infection model that takes into account cell-cell and virus-cell transmission and multiple treatment modalities. The desired control strategy is realized by means of a fractional order PD controller. Firstly, we calculated the basic regeneration number and equilibrium point of the HBV model. Afterwards, for the uncontrolled HBV virus system, the adequate conditions for both stability and Hopf bifurcation are systematically investigated via choosing the appropriate time delay as a parameter for bifurcation. Subsequently, under fractional order PD controller, the effect of a proposed controller on system stability and Hopf bifurcation is studied. The desired dynamic characteristics can be obtained afterwards. Finally, numerical simulations show that all three treatments significantly reduce R 0. The onset of oscillations can be delayed by decreasing the order of the fractional order. There are three control pathways for fractional order PD control, and the generation of bifurcation can also be delayed by changing the gain parameter. Using the above methods, the diffusion of HBV virus particles in the body can be effectively controlled. The conclusions drawn in this paper are extremely novel and have potential theoretical value for the future treatment of hepatitis B illness. [ABSTRACT FROM AUTHOR]