Search

This paper investigates the effects of trade regionalism in East Asia from 1995 to 2018, by applying a series of gravity models. An initial, basic gravity model is repeatedly augmented to account for a range of economic, geographical, cultural, and above all institutional factors representing free trade agreements in effect. Unlike previous studies, this investigation distinguishes between the bilateral and multilateral measures of regional trading arrangements. Two interesting findings are reported. First, the results confirm the impact of trade regionalism on the export flows between the economies of East Asia in the period under study. Second, the effects of multilateral trading agreements vary greatly depending on the agreement and on the particular country's range of influence, in particular cases showing no sufficient economic benefits. Overall, the results point to the complementarity of bilateral and multilateral trading arrangements in the region and to the emergence of a certain distinctive model of cooperation and integration in East Asia – which has been underpinned during the COVID-19 pandemic by the conclusion of the Regional Comprehensive Economic Partnership (RCEP), and which will be further verified in the post-COVID character of global trade and regional trading arrangements. [ABSTRACT FROM AUTHOR]

Contact tracing forms a crucial part of the public-health toolbox in mitigating and understanding emergent pathogens and nascent disease outbreaks. Contact tracing in the United States was conducted during the pre-Omicron phase of the ongoing COVID-19 pandemic. This tracing relied on voluntary reporting and responses, often using rapid antigen tests due to lack of accessibility to PCR tests. These limitations, combined with SARS-CoV-2's propensity for asymptomatic transmission, raise the question "how reliable was contact tracing for COVID-19 in the United States"? We answered this question using a Markov model to examine the efficiency with which transmission could be detected based on the design and response rates of contact tracing studies in the United States. Our results suggest that contact tracing protocols in the U.S. are unlikely to have identified more than 1.65% (95% uncertainty interval: 1.62-1.68%) of transmission events with PCR testing and 1.00% (95% uncertainty interval 0.98-1.02%) with rapid antigen testing. When considering a more robust contact tracing scenario, based on compliance rates in East Asia with PCR testing, this increases to 62.7% (95% uncertainty interval: 62.6-62.8%). We did not assume presence of asymptomatic transmission or superspreading, making our estimates upper bounds on the actual percentages traced. These findings highlight the limitations in interpretability for studies of SARS-CoV-2 disease spread based on U.S. contact tracing and underscore the vulnerability of the population to future disease outbreaks, for SARS-CoV-2 and other pathogens. [ABSTRACT FROM AUTHOR]

The sudden outbreak of the COVID-19 pandemic has changed people's long-standing group life, and "less gathering" has become a popular slogan during this period. People will probably feel lonely when they are physically, socially, or mentally distanced and isolated or excluded, and they usually perceive a deficiency in the quality or quantity of their social relationships. Although loneliness is easily conflated with solitude, loneliness as an emotion is generally regarded as negative while solitude can be positive. There are various causes and effects of loneliness during the COVID-19 pandemic, and loneliness has been found to have significant impacts on poorer physical and mental health. Religiosity and spirituality are specifically proven to have a great impact on handling loneliness during the COVID-19 pandemic. When regarding belongingness as the opposite of loneliness and social isolation, religious belonging means a feeling of being "at home" and "connected". In this paper, from a comparative approach, we attempt to investigate how the three most prominent traditions in East Asia, i.e., Confucianism, Daoism, and Buddhism, can help manage the feeling of loneliness. Due to different understandings of loneliness, their coping strategies for loneliness also vary. Through a preliminary study of "benevolence and rites," "wu-wei and freedom," and "mindfulness and spiritual realization," we can learn from the ancient wisdom about how to reduce loneliness and promote spiritual well-being during the COVID-19 pandemic. [ABSTRACT FROM AUTHOR]

This paper examines three of the COVID-19 pandemic's "known" impacts to date: its widespread and fundamental altering of government policy priorities; record low oil prices and its role in further escalating already heightened levels of strategic competition in East Asia and weakening of the existing multilateral order. The paper then uses some of the observed outcomes of these changes under the pandemic so far, in addition to additional evidence and causal linkages drawn from past research, to assess COVID-19's potential, but still unknown, longer term influence on marine plastic pollution and overfishing in the South China Sea, two of East Asia's most pressing marine environmental problems. In addition to flagging potential COVID-19 linked issues of concern in these two important policy areas, this approach also may assist further inquiry into the pandemic's still unknown potential to undermine environmental protection and regulatory efforts in other environmental issue areas. [ABSTRACT FROM AUTHOR]

Copyright of Zbornik Radova Pravnog Fakulteta u Nisu is the property of Law Faculty in Nis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Following the outbreak of what would become the COVID-19 pandemic, social distancing measures were quickly introduced across East Asia—including drastic shelter-in-place orders in some cities—drawing on experience with the outbreak of severe acute respiratory syndrome (SARS) almost two decades ago. "Smart City" technologies and other digital tools were quickly deployed for infection control purposes, ranging from conventional thermal scanning cameras to digital tracing in the surveillance of at-risk individuals. Chatbots endowed with artificial intelligence have also been deployed to shift part of healthcare provision away from hospitals and to support a number of programmes for self-management of chronic disease in the community. With the closure of schools and adults working from home, digital technologies have also sustained many aspects of both professional and social life at a pace and scale not considered to be practicable before the outbreak. This paper considers how these new experiences with digital technologies in public health surveillance are spurring digitalization in East Asian societies beyond the conventional public health context. It also considers some of the concerns and challenges that are likely to arise with rapid digitalization, particularly in healthcare. [ABSTRACT FROM AUTHOR]

Differences in public health approaches to control the coronavirus disease 2019 (COVID-19) pandemic could largely explain substantial variations in epidemiological indicators (such as incidence and mortality) between the West and the East. COVID-19 revealed vulnerabilities of most western countries' healthcare systems in their response to the ongoing public health crisis. Hence, western countries can possibly learn from practices from several East Asian countries regarding infrastructures, epidemiological surveillance and control strategies to mitigate the public health impact of the pandemic. In this paper, we discuss that the lack of rapid and timely community-centered approaches, and most importantly weak public health infrastructures, might have resulted in a high number of infected cases and fatalities in many western countries. [ABSTRACT FROM AUTHOR]

In an era of digitalization, governments often turn to digital solutions for pressing policy issues, and the use of digital contact tracing and quarantine enforcement for COVID-19 is no exception. The longterm impacts of the digital solutions, however, cannot be taken for granted. The development and use of data tools for pandemic control, for example, may have potentially detrimental and irreversible impacts on data governance and, more broadly, society, in the long run. In this paper, we aim to explore the extent to which COVID-19 and digital contact tracing have led to policy change in data governance, if at all, and what the implications of such change would be for a post-COVID world. We compare the use of contact tracing and monitoring applications across mainland China, Hong Kong, and Singapore to illustrate both the enormous benefits and potential risks arising from the design of contact tracing applications and the involvement of stakeholders in the various stages of the policy cycle to combat the COVID-19 pandemic. We argue that, while COVID-19 has not changed the nature of issues, such as public trust in data governance, the increasing involvement of big tech in data policies, and data privacy risks, it has exacerbated those issues through the accelerated adoption of data technologies. [ABSTRACT FROM AUTHOR]

The COVID pandemic has hit every person and organization by storm. In international education, stakeholders are diverse, bringing complex needs and considerations. Institutional responses to the pandemic are not amenable to broad replicability due to the contextualized nature in which international schools are situated, yet they are nonetheless of interest, particularly regarding the development of effective practices in times of pandemic. This paper explores some reflections of educators and leaders at international schools in south, southeast, and east Asia, in some of the first geographic areas to be affected by COVID-19, as they continue to face this crisis from personal and professional standpoints. The effects include higher levels of acculturative stress, but also the presence of hope and resilience. One education hub organization provides a medium-term visionary response, which is practical and potentially beneficial to multiple stakeholders in international education, as educational organizations consider best practices in terms of adaptive leadership in response to a pandemic. [ABSTRACT FROM AUTHOR]

Precisely because public health crises are uncertain, complex and have multiple dimensions, deeper institutional state capacity is needed. This article develops an approach to thinking about state capacity by incorporating time as a key component of a refurbished idea of state capacity. This reorientation helps us understand the specific mechanisms, especially of learning – that were crucial for the success of East Asian cases in managing the COVID-19 epidemic. Previous exposure to a health crisis – a critical juncture – activates learning capacity via two distinct mechanisms, one a political route of that restores public trust and renews the social contract, and the second through a functional route leading to administrative capacity building necessitated by a complex and multiplex crisis that crosses a variety of boundaries. Learning that builds coordinating state capacity is therefore needed. This article applies these ideas to understanding the successful pathway cases of South Korea and Taiwan. [ABSTRACT FROM AUTHOR]

Antimicrobials have allowed medical advancements over several decades. However, the continuous emergence of antimicrobial resistance restricts efficacy in treating infectious diseases. In this context, the drug repositioning of already known biological active compounds to antimicrobials could represent a useful strategy. In 2002 and 2003, the SARS-CoV pandemic immobilized the Far East regions. However, the drug discovery attempts to study the virus have stopped after the crisis declined. Today's COVID-19 pandemic could probably have been avoided if those efforts against SARS-CoV had continued. Recently, a new coronavirus variant was identified in the UK. Because of this, the search for safe and potent antimicrobials and antivirals is urgent. Apart from antiviral treatment for severe cases of COVID-19, many patients with mild disease without pneumonia or moderate disease with pneumonia have received different classes of antibiotics. Diarylureas are tyrosine kinase inhibitors well known in the art as anticancer agents, which might be useful tools for a reposition as antimicrobials. The first to come onto the market as anticancer was sorafenib, followed by some other active molecules. For this interesting class of organic compounds antimicrobial, antiviral, antithrombotic, antimalarial, and anti-inflammatory properties have been reported in the literature. These numerous properties make these compounds interesting for a new possible pandemic considering that, as well as for other viral infections also for CoVID-19, a multitarget therapeutic strategy could be favorable. This review is meant to be an overview on diarylureas, focusing on their biological activities, not dwelling on the already known antitumor activity. Quite a lot of papers present in the literature underline and highlight the importance of these molecules as versatile scaffolds for the development of new and promising antimicrobials and multitarget agents against new pandemic events. [ABSTRACT FROM AUTHOR]

During the first year of the pandemic, East Asian countries have reported fewer infections, hospitalizations, and deaths from COVID-19 disease than most countries in Europe and the Americas. Our goal in this paper is to generate and evaluate hypothesis that may explain this striking fact. We consider five possible explanations: (1) population age structure (younger people tend to have less severe COVID-19 disease upon infection than older people); (2) the early adoption of lockdown strategies to control disease spread; (3) genetic differences between East Asian population and European and American populations that confer protection against COVID-19 disease; (4) seasonal and climactic contributors to COVID-19 spread; and (5) immunological differences between East Asian countries and the rest of the world. The evidence suggests that the first four hypotheses are unlikely to be important in explaining East Asian COVID-19 exceptionalism. Lockdowns, in particular, fail as an explanation because East Asian countries experienced similarly good infection outcomes despite vast differences in lockdown policies adopted by different countries to control the COVID-19 epidemic. The evidence to date is consistent with our fifth hypothesis – pre-existing immunity unique to East Asia – but there are still essential parts of this story left for scientists to check. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic has affected all areas of our lives. Among other outcomes, the academic literature and popular media both discuss the potential effects of the pandemic on fertility. As fertility is an important determinant of population development and population forecasts are important for policy decisions and planning, we need to address to which extent fertility forecasts performed before the pandemic still apply. Using Monte Carlo forecasting based on principal components of fertility rates, we quantify the effects of the pandemic on fertility for 22 countries and discuss whether forecasts made prior to the pandemic need adjustment based on more recent data. Among the studied countries, 14 countries show no significant effect of the pandemic at all, while six countries have significantly lowered numbers of births in comparison to counterfactual trajectories that assume that past trends will hold. These countries are primarily in the Mediterranean and East Asia. For Finland and South Korea, there is statistical evidence for increased fertility in the early phases of the pandemic. In all cases with statistically significant fertility differentials caused by the pandemic, reproductive behavior normalized quickly. Therefore, we find no evidence for long-term effects of the pandemic on fertility, leading to the conclusion that pre-pandemic fertility forecasts still apply. [ABSTRACT FROM AUTHOR]

Objective: To assess the incidence and perinatal outcomes of COVID-19 in pregnant women in the Far Eastern and Siberian Federal Districts of Russian Federation over 10 months of a pandemic. Materials and methods: This was secondary analysis of Public Data basis on 25 Dec 2020. Statistics included descriptive statistics, analysis of contingency tables, which assessed the value of x², the achieved significance level (p). Results: During the first year of the SARS-CoV-2 pandemic, 8485 cases of COVID-19 were registered in pregnant women in the Far Eastern Federal District and the Siberian Federal District, accounting for 5.9% of registered pregnant women and 1.71% of the total affected population. The morbidity rate in pregnant women was 3.02 times higher than in the general population: 5933.2 vs 1960.8 per 100 thousand population. 27.4% of mothers had asymptomatic disease; 52.7% – mild; 16.6% – moderate, 2.5% – severe, 0.5% – critical disease. The incidence of hospitalization in ICU of pregnant women was higher relative to the general population (3.57% vs 2.24%, p < .001), but the frequency of mechanical ventilation was lower (0.48% vs 1.05%, p < .001). Preterm delivery had 18.3% (p < .001 CS - 42.0%. The mortality rate in pregnant women was 0.14% vs 1.95% – in the general population (p < .001). Perinatal mortality was 37 cases (1.56%), of which there were 31 stillbirths (1.26%), and 6 (0.25%) cases of early neonatal mortality. 148 (6.2%) COVID-19(þ) newborns were identified, despite anti-epidemic measures. Conclusion: The incidence of COVID-19 in pregnant women in Siberia and the Far East is higher than in the general population, but the disease is characterized by a milder. Women with COVID-19 have a high rate of preterm birth and CS. 148 (6.2%) newborns isolated COVID-19. [ABSTRACT FROM AUTHOR]

With the outbreak of the COVID-19 pandemic, many seismologists all over the world have noted a sharp (up to 30–50%) decrease in the daily background seismic noise during the period from March to May, 2020 (Lecocq et al., Science 369(6509):1338–1343, 2020). The authors studied the influence of the self-isolation regime introduced in the Russian Federation from March 30, 2020 and, as a consequence, the restriction of the work of public institutions and the mobility of the population, on the quality of seismological observations at seismic stations in large cities of the Russian Far East for the period from March 23, 2020 to April 12, 2020. The work analyses the records of seismic noise by the seismic stations of Khabarovsk and Vladivostok located in busy parts of the cities and, accordingly, strongly influenced by anthropogenic impact, as well as it analyses the records of the Yuzhno-Sakhalinsk seismic station located in the relatively «calm» part of the city. Power spectra and temporal variations of microseismic noise levels for the listed above seismic stations were constructed based on the data of broadband seismometers records in the range of 1–20 Hz. The analysis of noise level variations with the data on the population mobility was carried out on the basis of self-isolation index by Yandex, which shows the level of town activity over a selected period. The main sources of the increased microseismic noise at seismic stations were identified. [ABSTRACT FROM AUTHOR]

Background: The novel 2019 coronavirus disease (COVID-19), which is caused by infection with the severe acute respiratory syndrome coronavirus 2, has spread rapidly around the world and has caused many deaths. COVID-19 involves a systemic hypercoagulable state and arterial/venous thrombosis which induces unfavorable prognosis. Herein, we present a first case in East Asia where an acute superior mesenteric artery (SMA) occlusion associated with COVID-19 pneumonia was successfully treated by surgical intervention. Case presentation: A 70-year-old man presented to his local physician with a 3-day history of cough and diarrhea. A real-time reverse transcriptase-polymerase chain reaction test showed positive for COVID-19, and he was admitted to the source hospital with the diagnosis of moderate COVID-19 pneumonia. Eight days later, acute onset of severe abdominal pain appeared with worsening respiratory condition. Contrast CT showed that bilateral lower lobe/middle lobe and lingula ground glass opacification with distribution suggestive of COVID-19 pneumonia and right renal infarction. In addition, it demonstrated SMA occlusion with intestinal ischemia suggesting extensive necrosis from the jejunum to the transverse colon. The patient underwent an emergency exploratory laparotomy with implementing institutional COVID-19 precaution guideline. Upon exploration, the intestine from jejunum at 100 cm from Treitz ligament to middle of transverse colon appeared necrotic. Necrotic bowel resection was performed with constructing jejunostomy and transverse colon mucous fistula. We performed second surgery to close the jejunostomy and transverse colon mucous fistula with end-to-end anastomosis on postoperative day 22. The postoperative course was uneventful and he moved to another hospital for rehabilitation to improve activities of daily living (ADLs) on postoperative day 45. As of 6 months after the surgery, his ADLs have completely improved and he has returned to social life without any intravenous nutritional supports. Conclusions: Intensive treatment including surgical procedures allowed the patient with SMA occlusion in COVID-19 pneumonia to return to social life with completely independent ADLs. Although treatment for COVID-19 involves many challenges, including securing medical resources and controlling the spread of infection, when severe abdominal pain occurs in patients with COVID-19, physicians should consider SMA occlusion and treat promptly for life-saving from this deadly combination. [ABSTRACT FROM AUTHOR]

Background: In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, raised worldwide concern. Since then, the COVID-19 pandemic has negatively influenced health and wellness across the globe and caused nearly three million deaths. This study focuses on informal caregivers of people with dementia, a disease that affects about 50 million older adults worldwide and requires much caregiving support. Objective : Examine the current literature on the impact of COVID-19 on the health and well-being of informal caregivers for people with dementia. Method : This rapid review was conducted across five electronic databases for quantitative and qualitative articles published through March 15, 2021. Results : The 10 studies included in this review reported quantitative descriptive data from across the globe; however, no studies existed from the U.S. or East Asia countries. All of the studies examined the psychological rather than physical impact of COVID-19 and highlighted risk and protective factors in the areas of psychosocial (resilience, neuropsychiatric, and social isolation), sociodemographic (gender and education), and environmental (home confinement, living arrangement, and dementia stage). Conclusion : COVID-19 has had a considerable negative impact on the psychological well-being of informal caregivers of people with dementia, namely causing more depression and anxiety than pre-pandemic. [ABSTRACT FROM AUTHOR]

Wearing masks against 2019 coronavirus (COVID-19) is beneficial in suppressing pandemic spread, not through preventing the wearer from being infected but by preventing the wearer from infecting others. Despite not providing much protection, the custom of wearing masks has prevailed in East Asia from the early stages of the pandemic, especially in Japan, to such an extent that it caused a shortfall in supply. Why do many Japanese people wear masks during the COVID-19 pandemic, even though masks are unlikely to prevent them from getting infected? We examined six possible psychological reasons for wearing masks: three involved expectations about the risk of infection and three involved other driving psychological forces. The results of our nationwide survey revealed that people conformed to societal norms in wearing masks and felt relief from anxiety when wearing masks. However, risk reduction expectations did not affect mask usage. The social psychological motivations successfully explained much about mask usage. Our findings suggest that policymakers responsible for public health should consider social motivations when implementing public strategies to combat the COVID-19 pandemic. [ABSTRACT FROM AUTHOR]

Shortly after the outbreak of the novel infectious disease (COVID-19) started at the end of 2019, it turned into a global pandemic, which caused the lockdown of many countries across the world. Various strict measures were adopted to reduce anthropogenic activities in order to prevent further spread and infection of the disease. In this study, we utilized continental scale remotely sensed data along with city scale in situ air quality observations for 2020 as well as data from the baseline period (2015–2019) to provide an early insight on air pollution changes in response to the COVID-19 pandemic lockdown, by combining both continental and city scales. For the continental scale analysis, data of NO2, SO2, and O3 were acquired from the ozone monitoring instrument (OMI) and data of aerosol optical depth (AOD) were collected from the moderate resolution imaging spectroradiometer (MODIS). For city scale analysis, data of NO2, CO, PM2.5, O3, and SO2 were derived from ground-based air quality observations. Results from satellite observations at the continental scale showed that concentrations of NO2, SO2, and AOD substantially dropped in 2020 during the lockdown period compared to their averages for the baseline period over all continents, with a maximum reduction of ~33% for NO2 in East Asia, ~41% for SO2 in East Asia, and ~37% for AOD in South Asia. In the case of O3, the maximum overall reduction was observed as ~11% in Europe, followed by ~10% in North America, while a slight increase was found in other study regions. These findings align with ground-based air quality observations, which showed that pollutants such as NO2, CO, PM2.5, and SO2 during the 2020 lockdown period decreased significantly except that O3 had varying patterns in different cities. Specifically, a maximum reduction of ~49% in NO2 was found in London, ~43% in CO in Wuhan, ~38% in PM2.5 in Chennai, and ~48% in SO2 in Beijing. In the case of urban O3, a maximum reduction of ~43% was found in Wuhan, but a significant increase of ~47% was observed in Chennai. It is obvious that restricted human activities during the lockdown have reduced the anthropogenic emissions and subsequently improved air quality, especially across the metropolitan cities. [ABSTRACT FROM AUTHOR]