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Road traffic injuries account for 1.3 million deaths per year world-wide. Mitigating both fatalities and injuries requires a detailed understanding of the tolerance of the human body to external load. To identify research priorities, it is necessary to periodically compare trends in injury tolerance research to the characteristics of injuries occurring in the field. This study sought to perform a systematic review on the last twenty years of experimental injury tolerance research, and to evaluate those results relative to available epidemiologic data. Four hundred and eight experimental injury tolerance studies from 1990–2009 were identified from a reference index of over 68,000 papers. Examined variables included the body regions, ages, and genders studied; and the experimental models used. Most (20%) of the publications studied injury to the spine. There has also been a substantial volume of biomechanical research focused on upper and lower extremity injury, thoracic injury, and injury to the elderly – although these injury types still occur with regularity in the field. In contrast, information on pediatric injury and physiological injury (especially in the central nervous system) remains lacking. Given their frequency of injury in the field, future efforts should also include improving our understanding of tolerances and protection of vulnerable road users (e.g., motorcyclists, pedestrians). [ABSTRACT FROM AUTHOR]

In 2016, Colombia's position regarding motorcyclist fatalities per 100,000 inhabitants was tenth worldwide and second in South America. In the seven years from 2012-2018, the proportion of deceased and injured motorcyclists among all road users was 50%. To analyse the significant aspects of the accident rate of motorcyclists in Colombia from 2016 to 2018 and estimate cost social value of motorcycle-related deaths. The global numbers of fatalities and injuries were compared to the Colombian context. Descriptive and inferential statistics were conducted to explore the association of fatal trauma and motorcycle accidents. P values and odds ratios were calculated. Bogotá, Cali, and Medellín were the cities with the most accidents. The month, day, time, age of the victims, and climatic conditions had a statistically significant association with the fatal trauma. Most victims were between the ages of 20-29 years. Motorcycles were involved in more than 60% of accidents. The social cost of a life lost in a motorcycle accident was estimated at $2,418 million Colombian pesos (725,400 USD) per year. The establishment of countermeasures for the road safety of vulnerable users should focus on associated causal factors in order to develop strategies to effectively reduce the number of accidents. [ABSTRACT FROM AUTHOR]

• NASS CDS data have been augmented with information on each vehicle's pre-tensioner and force limiter seat belt systems. • Multivariate logistic regression models were developed to assess the real-world effectiveness of advanced seat belt systems. • The presence of load-limiting devices was significantly associated with preventing fatal injuries. • The use of low-force load-limiting devices (<4.5 kN) was associated with reducing the risk of whole-body AIS3+ injuries. • Slight deviations from the pure frontal direction in the collision resulted in an increased risk of AIS2+ and AIS3+ injuries. Contemporary research has pointed out that while newer cars are contributing to the decrease of AIS2+ and AIS3+ injuries in several body regions, this effect is not shown for thoracic injuries like rib or sternal fractures. The objective of this study is to assess the effectiveness of advanced seat belt systems incorporating pre-tensioners and load limiters in the prevention of fatal, AIS2+ and AIS3+ injuries overall and then focus only on the head-face-neck and thoracic areas. Data from the NASS CDS database between 2000 and 2015 was augmented with specific vehicle information taken from NHTSA's NCAP tests to identify the characteristics of the seat belt of each vehicle involved in a collision. Multivariate logistic regressions were developed to assess the likelihood of injuries for belted front seat occupants in frontal impacts. The presence of pre-tensioners and load limiters with a low load limiter (<4.5 kN) was significantly associated with a decreased risk of fatal and AIS3+ in the whole body (OR = 0.31 (p < 0.05) and OR = 0.70 (p < 0.1)), while high load limiters were significant in the prevention of fatal injuries (OR = 0.42). These effects should be considered always in combination with the delta-v of the collision, as the interaction term between delta-v and advanced seat belt features was significant. In the crashes considered, the model predicted a higher risk of injury for women compared to men, controlling for other occupant and crash factors. Impacts with a slightly oblique component increased the risk of injury compared to pure frontal impacts. After controlling for the presence of pre-tensioners and load limiters, the vehicle model year variable was found to be insignificant in any of the regression models. This study shows that the real-world effectiveness of advanced seat belts still requires further analysis. Other effects like age or impact direction might be more influential in the injury outcome than these seat belt features. [ABSTRACT FROM AUTHOR]

Bone is a heterogeneous, hierarchical biocomposite material made of an organic matrix filled with a mineral component, which plays an important role in bone strength. Although the effect of the mineral/matrix ratio on the mechanical properties of bone during aging has been intensively investigated, the relationship between the mechanical properties and the chemical composition of bone with age requires additional research in juvenile individuals. In this study, bone coupons from bovine and ovine animal species were machined from cortical areas of long bones to quantify whether the variation in mechanical properties at different stages of development is related to the change in the composition of bone tissue. An energy-dispersive X-ray detector (EDX) attached to a scanning electron microscope (SEM) was used to perform a compositional analysis of the tissue. In addition, nanoindentation analyses were carried out to address how the elastic modulus changed with age. Nonparametric statistical analyses found significant differences (p < 0.05) in Ca content and elastic modulus between species, but no differences were found within each species with development. A multiple linear regression model found that the elastic modulus was significantly related to the decrease in P and C in the samples, to the animal species (larger in bovine), and development, although not linearly. This model also found an interaction between Ca and development that could explain the lack of significance of the relationship between the elastic modulus and development in the univariate models. [ABSTRACT FROM AUTHOR]

CO 2 emissions are one of the major contributors to global warming. The variety of emission sources and the nature of CO 2 hinders estimating its concentration in real time and therefore to adopt flexible policies that contribute to its control and, ultimately, to reduce its effects. Spain is not exempted from this challenge and CO 2 emissions are published only at the end of the year and as an aggregated value for the whole country, without recognising the existing differences between the regions (the so-called, Autonomous Communities). The recent COVID-19 pandemic is a clear example of the need of accurate and fast estimation methods so that policies can be tailored to the current status and not to a past one. This paper provides a method to estimate monthly emissions of CO 2 for each AACC in Spain based on data that are published monthly by the relevant administrations. The paper discusses the approximations needed in the development of the method, predicts the drop in emissions due to the reduced industrial activity during the pandemic in Spain and provides the estimation of future emissions under three recovery scenarios after the pandemic. [ABSTRACT FROM AUTHOR]