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295 results on '"Zhang, Yunting"'

5. Assessing Feasibility of an Early Childhood Intervention Using Mobile Phones Among Low-Income Mothers of Newborns: Qualitative Interview Study

Author

Zhang, Donglan, Jin, Lan, Liang, Di, Geng, Ruijin, Liu, Yun, Ling, Yu, Jiang, Fan, and Zhang, Yunting

Subjects
Medicine
Abstract

BackgroundMany children aged younger than 5 years living in low- and middle-income countries are at risk for poor development. Early child development (ECD) programs are cost-effective strategies to reduce poverty, crime, school dropouts, and socioeconomic inequality. With the spread of low-cost mobile phones and internet access in low- and middle-income countries, new service delivery models such as mobile phone–aided interventions have a great potential to improve early childhood development. ObjectiveThis study aimed to identify the beliefs on importance of ECD, feasibility of a proposed intervention using mobile phones and factors that may affect the usability of the intervention among mothers of newborns in a poverty-stricken area in southwestern China. MethodsWe conducted an in-depth, semistructured interview study of 25 low-income mothers of newborns recruited from two county hospitals in Yunnan Province. We applied the health belief model and cultural competence theories to identify the facilitators, barriers, and preferences among the target population for parenting knowledge. ResultsThe results showed that the participants had low health literacy and high perceived needs for learning ECD knowledge. At the same time, they experienced several barriers to learning parenting information and following evidence-based instructions including having limited time, limited financial resources, and different opinions on childcare among family members. Many participants preferred to receive personalized messages tailored to their specific needs and preferred videos or graphics to text only in the messages. Many favored a separate module to support postpartum mental health. ConclusionsThe study assessed the acceptability of an early childhood intervention using mobile phones to meet the needs of the target population based on their beliefs, traits, and preferences and provided suggestions to refine the intervention to improve its usability.

Published
2020
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7. Inter-brain substrates of role switching during mother-child interaction

Author

Li, Yamin, Wu, Saishuang, Xu, Jiayang, Wang, Haiwa, Zhu, Qi, Shi, Wen, Fang, Yue, Jiang, Fan, Tong, Shanbao, Zhang, Yunting, and Guo, Xiaoli

Subjects
Quantitative Biology - Neurons and Cognition
Abstract

Mother-child interaction is highly dynamic and reciprocal. Switching roles in these back-and-forth interactions serves as a crucial feature of reciprocal behaviors while the underlying neural entrainment is still not well-studied. Here, we designed a role-controlled cooperative task with dual EEG recording to study how differently two brains interact when mothers and children hold different roles. When children were actors and mothers were observers, mother-child inter-brain synchrony emerged within the theta oscillations and the frontal lobe, which highly correlated with children's attachment to their mothers. When their roles were reversed, this synchrony was shifted to the alpha oscillations and the central area and associated with mothers' perception of their relationship with their children. The results suggested an observer-actor neural alignment within the actor's oscillations, which was modulated by the actor-toward-observer emotional bonding. Our findings contribute to the understanding of how inter-brain synchrony is established and dynamically changed during mother-child reciprocal interaction.

Published
2023
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28. Individual and joint associations of long-term exposure to air pollutants and cardiopulmonary mortality: a 22-year cohort study in Northern China

Author

Huang, Wenzhong, Zhou, Yang, Chen, Xi, Zeng, Xiaowen, Knibbs, Luke D., Zhang, Yunting, Jalaludin, Bin, Dharmage, Shyamali C., Morawska, Lidia, Guo, Yuming, Yang, Xueli, Zhang, Liwen, Shan, Anqi, Chen, Jie, Wang, Tong, Heinrich, Joachim, Gao, Meng, Lin, Lizi, Xiao, Xiang, Zhou, Peien, Yu, Yunjiang, Tang, Naijun, and Dong, Guanghui

Published
2023
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44. Identifying potential anthocyanin biosynthesis regulator in Chinese cherry by comprehensive genome-wide characterization of the R2R3-MYB transcription factor gene family.

Author

Wang, Yan, Tu, Hongxia, Zhang, Jing, Wang, Hao, Liu, Zhenshan, Zhou, Jingting, He, Wen, Lin, Yuanxiu, Zhang, Yunting, Li, Mengyao, Wu, Zhiwei, Chen, Qing, Zhang, Yong, Luo, Ya, Tang, Haoru, and Wang, Xiaorong

Subjects
TRANSCRIPTION factors, MYB gene, FRUIT skins, COLOR variation (Biology), GENETIC transcription regulation
Abstract

Background: Chinese cherry [Cerasus pseudocerasus (Lindl.) G.Don] (syn. Prunus pseudocerasus Lindl.) is an economically important fruiting cherry species with a diverse range of attractive colors, spanning from the lightest yellow to the darkest black purple. However, the MYB transcription factors involved in anthocyanin biosynthesis underlying fruit color variation in Chinese cherry remain unknown. Results: In this study, we characterized the R2R3-MYB gene family of Chinese cherry by genome-wide identification and compared it with those of 10 Rosaceae relatives and Arabidopsis thaliana. A total of 1490 R2R3-MYBs were classified into 43 subfamilies, which included 29 subfamilies containing both Rosaceae MYBs and AtMYBs. One subfamily (S45) contained only Rosaceae MYBs, while three subfamilies (S12, S75, and S77) contained only AtMYBs. The variation in gene numbers within identical subfamilies among different species and the absence of certain subfamilies in some species indicated the species-specific expansion within MYB gene family in Chinese cherry and its relatives. Segmental and tandem duplication events primarily contributed to the expansion of Chinese cherry R2R3-CpMYBs. The duplicated gene pairs underwent purifying selection during evolution after duplication events. Phylogenetic relationships and transcript profiling revealed that CpMYB10 and CpMYB4 are involved in the regulation of anthocyanin biosynthesis in Chinese cherry fruits. Expression patterns, transient overexpression and VIGS results confirmed that CpMYB10 promotes anthocyanin accumulation in the fruit skin, while CpMYB4 acts as a repressor, inhibiting anthocyanin biosynthesis of Chinese cherry. Conclusions: This study provides a comprehensive and systematic analysis of R2R3-MYB gene family in Chinese cherry and Rosaceae relatives, and identifies two regulators, CpMYB10 and CpMYB4, involved in anthocyanin biosynthesis in Chinese cherry. These results help to develop and utilize the potential functions of anthocyanins in Chinese cherry. [ABSTRACT FROM AUTHOR]

Published
2024
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45. A Lancet Commission on 70 years of women's reproductive, maternal, newborn, child, and adolescent health in China

Author

Qiao, Jie, Wang, Yuanyuan, Li, Xiaohong, Jiang, Fan, Zhang, Yunting, Ma, Jun, Song, Yi, Ma, Jing, Fu, Wei, Pang, Ruyan, Zhu, Zhaofang, Zhang, Jun, Qian, Xu, Wang, Linhong, Wu, Jiuling, Chang, Hsun-Ming, Leung, Peter C K, Mao, Meng, Ma, Duan, Guo, Yan, Qiu, Jie, Liu, Li, Wang, Haidong, Norman, Robert J, Lawn, Joy, Black, Robert E, Ronsmans, Carine, Patton, George, Zhu, Jun, Song, Li, and Hesketh, Therese

Published
2021
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49. Genome-Wide Analysis of Polygalacturonase Gene Family Reveals Its Role in Strawberry Softening.

Author

Zhao, Mantong, Hu, Ruixin, Lin, Yuanxiu, Yang, Yeqiao, Chen, Qing, Li, Mengyao, Zhang, Yong, Zhang, Yunting, Wang, Yan, He, Wen, Wang, Xiaorong, Tang, Haoru, and Luo, Ya

Subjects
GENE families, CELL membranes, POLYGALACTURONASE, HEMICELLULOSE, FRUIT, STRAWBERRIES
Abstract

Fruit softening is a prominent attribute governing both longevity on shelves and commercial worth. Polygalacturonase (PG) plays a major role in strawberry fruit softening. However, the PG gene family in strawberry has not been comprehensively analyzed. In this study, 75 FaPG genes were identified in the octoploid strawberry genome, which were classified into three groups according to phylogenetic analysis. Subcellular localization prediction indicated that FaPGs are mostly localized to the plasma membrane, cytoplasm, and chloroplasts. Moreover, the expression of FaPGs during strawberry development and ripening of 'Benihoppe' and its softer mutant was estimated. The results showed that among all 75 FaPGs, most genes exhibited low expression across developmental stages, while two group c members (FxaC_21g15770 and FxaC_20g05360) and one group b member, FxaC_19g05040, displayed relatively higher and gradual increases in their expression trends during strawberry ripening and softening. FxaC_21g15770 was selected for subsequent silencing to validate its role in strawberry softening due to the fact that it exhibited the highest and most changed expression level across different developmental stages in 'Benihoppe' and its mutant. Silencing FxaC_21g15770 could significantly improve strawberry fruit firmness without affecting fruit color, soluble solids, cellulose, and hemicellulose. Conversely, silencing FxaC_21g15770 could significantly suppress the expression of other genes related to pectin degradation such as FaPG-like, FaPL, FaPME, FaCX, FaCel, FaGlu, FaXET, and FaEG. These findings provide basic information on the FaPG gene family for further functional research and indicate that FxaC_21g15770 plays a vital role in strawberry fruit softening. [ABSTRACT FROM AUTHOR]

Published
2024
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