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Concerns over the supply of highly-skilled (HS) science, technology, engineering and maths (STEM) workers are well established and have been a feature of policy discourse in the UK for more than 50 years. Since the 2016 referendum on leaving the European Union, these concerns have been exacerbated by uncertainty about the movement of labour between UK and Europe. More recently, the COVID-19 pandemic has highlighted the importance of STEM skills in a wide range of areas. However, despite continued government investment in initiatives to address these concerns, the evidence base for shortages is neither well-established nor compatible with economic theories of labour supply. In order to fill a gap in the current evidence, we report on a unique analysis following the career destinations of STEM graduates from the 1970 British Cohort Study. While only a minority of STEM graduates ever work in highly-skilled STEM jobs, we identified three particular characteristics of the STEM labour market that may present challenges for employers: STEM employment appears to be predicated on early entry to the sector; a large proportion of STEM graduates are likely to never work in the sector; and there may be more movement out of HS STEM positions by older workers than in other sectors.

This paper explores patterns in participation in adult education and training (AET) by comparing five countries with high participation rates (the Nordic countries and the Netherlands) with three countries with significantly lower participation rates (France, Poland and the Slovak Republic). Using PIAAC data the paper examines differences in the levels of demand for AET as well as variations in barriers to AET participation between the two groups of countries. The demand for AET is higher than the actual participation rate since it includes those who do not participate although they wish to. The demand for AET is substantially higher in countries with high participation rates. Further, the structure and level of barriers is quite similar in the two groups of countries. Countries with low AET participation rate do not have a higher proportion of individuals reporting barriers to AET participation; that they do not participate in AET although they wish to. In both groups of countries demand for AET is strongly associated with the individuals' educational level. The findings are discussed by drawing on previous studies on drivers of and barriers to participation in AET.

Generation Y can be taken to be the group of people born between 1977 and 2000. The aim of this paper is to investigate the initial career entry and long-term career employment expectations of UK undergraduate Generation Ys, in order to inform employability skills development in higher education. The empirical research comprises 26 focus groups with 172 undergraduates of this generation in 2 universities in the UK. The focus group participants are found predominantly to have high expectations of their employment in enjoyment, opportunity and progression. Overall, the respondents appear enthusiastic and optimistic, with a positive work ethic and healthy mindset. Fundamentally, recognising and appreciating undergraduate Generation Ys' opinions on their employment expectations enables development of their employability skills while they are in university. The paper sets out implications for higher educational stakeholders including students, graduates and employers on the development of employability skills.

The evaluation of sign language proficiency needs to be based on measures with well-established psychometric proprieties. To date, no valid and reliable test is available to assess Polish Sign Language ("Polski Jezyk Migowy," PJM) skills in deaf children. Hence, our aim with this study was to adapt the British Sign Language Receptive Skills Test (the first standardized test to determine sign language proficiency in children) into PJM, a less researched sign language. In this paper, we present the first steps in the adaptation process and highlight linguistic and cultural similarities and differences between the British Sign Language Receptive Skills Test and the PJM adaptation. We collected data from 20 deaf children who were native signers (age range: 6 to 12) and 30 deaf children who were late learners of PJM (age range: 6 to 13). Preliminary analyses showed that the PJM Receptive Skills Test has acceptable psychometric characteristics (item analysis, validity, reliability, and sensitivity to age). Our long-term goal with this work was to include younger children (age range: 3 to 6) and to standardize the PJM Receptive Skills Tests, so that it can be used in educational settings and in scientific research.

The question of whether the potential short-term advantages of vocational qualifications are offset by disadvantages in later life is an important issue for policy debates. This paper analyses how the choice of vocational or general upper-secondary education affects future prospects of participation in non-formal education (NFE). It presents a comparative analysis of European countries in different six types according to the skill specificity of the vocational education and training system, using the 2014 Labour Force Survey data. Our results confirm the trade-off between short- and long-term benefits of vocational education. In countries with higher specificity of vocational education, the difference in NFE participation between vocational and general upper-secondary education at the beginning of the work career is higher compared to countries where specificity is lower. However, the same difference also appears in countries where general upper-secondary education dominates. Unexpectedly, the differences between the two educational groups in training participation did not diminish over the life-course but increased for the 30-34 year olds. The results highlight that in countries where general upper-secondary education dominates (type 6) those with vocational education are more likely to participate in NFE than in countries where school-based systems exist (type 5). Abbreviations: NFE - non-formal education and training; VET - vocational education and training; ISCED - International Standard Classification of Education; EU LFS - the European Union Labour Force Survey

Mortality at older ages varies by season, increasing the uncertainty associated with modelling and projecting mortality at older ages and ultimately contributing to pension providers' overall risk. As the population ages, it becomes more important to understand variations in seasonal mortality between pensioners and to identify those most vulnerable to seasonal mortality differences. Using data from the Self-Administered Pension Schemes mortality investigation of the Continuous Mortality Investigation of the Institute and Faculty of Actuaries, UK, this paper investigates variations in seasonal mortality amongst members of UK occupational pension schemes over the period 2000--2016. Results are also compared with the corresponding population of England and Wales. For the oldest age groups (80+), which are most affected by seasonality, females are more vulnerable to seasonal differences in mortality for each pensioner group relative to males. Following a long-term decline in the winter-summer mortality gap the gap increased over the period, particularly for female pensioners and dependants. Seasonality remains a feature of UK mortality at older ages and risk management for pension schemes should consider seasonality when analysing overall mortality experience. [ABSTRACT FROM AUTHOR]

Aim: To report the differential diagnosis in children with progressive intellectual and neurological deterioration (PIND) in the UK. Method: Since 1997 the PIND Study has searched for variant Creutzfeldt‐Jakob disease (vCJD) in children, using the British Paediatric Surveillance Unit to perform prospective surveillance of those younger than 16 years with PIND. Results: From May 1997 to October 2019, 2255 children meeting PIND criteria had been notified, of whom 2008 (1085 males, 923 females) had underlying diagnoses. There were over 220 different diseases, including six cases of vCJD. The numbers presenting in four age groups were: <1 year, 805 (40%); 1 to 4 years inclusive, 825 (41%); 5 to 9 years inclusive, 264 (13%); and 10 to 15 years inclusive, 114 (6%). The two largest ethnic groups were White and Pakistani (58.2% and 17% of diagnosed cases). The most common diseases in these two ethnic groups are shown for the four age groups. The distribution of diseases varied with age but was quite similar in White and Pakistani children. Interpretation: This paper provides a unique guide to the complex differential diagnosis of childhood PIND, showing considerable differences between four age groups, but similarities between ethnic groups. The PIND Study still provides the only systematic surveillance for vCJD in children in the UK. What this paper adds: The prevalence of diseases causing childhood progressive intellectual and neurological deterioration in the UK is low (approximately 0.1/1000 live births).There were more than 220 different disorders, mainly genetically determined.The majority of disorders presented early in childhood: 81% before the age of 5 years.There were similarities in the disease spectrum in White and Pakistani children. What this paper adds: The prevalence of diseases causing childhood progressive intellectual and neurological deterioration in the UK is low (approximately 0.1/1000 live births).There were more than 220 different disorders, mainly genetically determined.The majority of disorders presented early in childhood: 81% before the age of 5 years.There were similarities in the disease spectrum in White and Pakistani children. Video Podcast: https://youtu.be/QbUG-ZVJLHc This article is commented on by van Karnebeek on page 243 of this issue. [ABSTRACT FROM AUTHOR]

Against a backdrop of increasing cultural visibility of people who identify across, between or beyond the categories of male and female, young people have been positioned within the wider social imaginary as radical trailblazers for a new, progressive gender order. This paper provides original insights that empirically ground and interrogate such claims. Drawing on findings from focus group interviews held with 136 young people (aged 16–24) in the UK, the paper demonstrates how young people's understandings and narrations of gender diversity both support and contest linear progress narratives. We show how young people position their acceptance of gender diversity in contradistinction to older generations. However, this narrative of generational progress was undermined and complicated by tensions and ambiguities within young people's talk. Our findings suggest that, alongside being accepting of gender diversity, young people also experience confusion and misunderstanding which may mean that they are more comfortable with stable and binary forms of gender diversity. Moreover, some young people express ideological resistance to gender diversity, informed by wider debates around 'identity politics'. Overall, we stress the importance of situating young people's gender talk amidst multiple discursive constellations through which increasingly politicised struggles around the meanings of 'gender' are currently playing out. [ABSTRACT FROM AUTHOR]

The prevention of fraud against older adults and other age groups, has been the subject of limited research with very few systematic attempts to map different tools and strategies that are used. This paper using the UK and South Korea as a starting point, but other countries too, maps some of the most common tools and strategies used to prevent frauds that target older adults. It develops the first comprehensive typology of strategies built upon the degree to which they embrace modern technology. It shows much of the prevention used is low tech, but high-tech solutions rooted in the fourth industrial revolution technologies are emerging and growing. The paper draws these different strategies and tools together to offer a holistic model for the prevention of fraud against older adults for further debate and utilisation by professionals. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this paper is to identify key countries and their focal research fields on the information divide. Design/methodology/approach: Literature was retrieved to identify key countries and their primary focus. The literature research method was adopted to identify aspects of the primary focus in each key country. Findings: The key countries with literature on the information divide are the USA, China, the UK and India. The problem of health is prominent in the USA, and solutions include providing information, distinguishing users' profiles and improving eHealth literacy. Economic and political factors led to the urban–rural information divide in China, and policy is the most powerful solution. Under the influence of humanism, research on the information divide in the UK focuses on all age groups, and solutions differ according to age. Deep-rooted patriarchal concepts and traditional marriage customs make the gender information divide prominent in India, and increasing women's information consciousness is a feasible way to reduce this divide. Originality/value: This paper is an extensive review study on the information divide, which clarifies the key countries and their focal fields in research on this topic. More important, the paper innovatively analyzes and summarizes existing literature from a country perspective. [ABSTRACT FROM AUTHOR]

This paper considers the impact of two measures of lifestyle—the consumption of fruit and vegetables and doing exercise—on individual well-being. Since lifestyle is likely to be endogenous, we correct for this by using two dimensions of delayed gratification as instruments. The ability to delay gratification enables individuals to give greater weight to the investment component of lifestyle decisions rather than merely the affective component. Our analysis is based on the UK Understanding Society Data, which covers 40,000 UK households over time. We find that the two delayed gratification instruments are positive and significant in influencing lifestyle. In Stage 2, we find that fruit and vegetable consumption and sports activity increase life satisfaction, though the impacts vary for men and women. These results are robust across income quartiles, region, gender, education and age groups. [ABSTRACT FROM AUTHOR]

Background: Centile curves and standard scores are common in epidemiological research. However, standardised norms and centile growth curves for language disorder that reflect the entire UK local school population do not exist. Methods: Scores on six language indices assessing receptive and expressive functioning of children were obtained from the SCALES population survey. Monolingual English speaking participants were aged between five and nine years. Children who attended special schools at study intake, or who were learning English as an additional language were excluded. We constructed language norms using the LMS method of standardisation which allows for skewed measurements. We made use of probability weights that were produced from a two-step logistic model. Distributions of estimated standard scores from an intensively assessed sub-population and from the full population were contrasted to demonstrate the role of weights. Results: Non-overlapping centile curves and standardised scores at each age were obtained for the six language indices. The use of weights was essential at retrieving the target distribution of the scores. An online calculator that estimates standardised scores for the measures was constructed and made freely available. Conclusions: The findings highlight the usefulness and flexibility of the LMS method at dealing with the standardisation of linguistic and educational measures that are sufficiently continuous. The paper adds to the existing literature by providing population norms for a number of language tests that were calculated from the same group of individuals. [ABSTRACT FROM AUTHOR]

Attitudes towards social groups that have traditionally been marginalised or discriminated against have changed markedly in Britain over the past three decades. This change is particularly marked in attitudes towards homosexuality and racial diversity which, as public opinion surveys have regularly shown, have become more accepting over time. This change is often attributed to older, less tolerant generations being replaced by young cohorts who are more inclusive and open minded in their attitudes to cultural others. The paper explores this argument by examining trends in people's attitudes towards a variety of minorities, including the said groups, but also immigrants and foreign workers. It starts with a discussion of several perspectives predicting different trends with regards to these attitudes. A distinction is made between optimistic ones (i.e. those anticipating rising levels of tolerance) and pessimistic ones (i.e. those expecting stable or declining levels of tolerance). Subsequently, the paper presents trend analyses and an analysis of age, cohort and period effects to broadly assess the explanatory power of these perspectives. Using these approaches, we find that tolerance towards racial minorities and homosexuality has indeed risen across the board, and that young people are also more accepting of these groups than their parents or grandparents and previous generations of young people. These trends broadly support the optimistic perspectives. However, we also find that prejudice has not disappeared from youth attitudes altogether; for a sizeable minority of youth, it has merely shifted its focus to immigration. Not only have unwelcoming attitudes towards immigrants generally become stronger, young people are not always the most tolerant age group regarding this social group. These findings are thus more in line with the expectations of the pessimistic perspectives. [ABSTRACT FROM AUTHOR]

We discuss a case study on how misinformation regarding Covid‐19 health outcomes can arise due to confounding. Data from the UK on mortality rates suggest that people who have some level of vaccination and contract the Delta variant of Covid are twice as likely to die than those who are unvaccinated. Age, however, a confounding variable, when accounted for, produces a more complicated picture. The mortality rates for the vaccinated are statistically lower than the unvaccinated for the older but not younger age group. We present several approaches for teaching confounding to help students better understand this underemphasized concept's cause, effects, and origins. [ABSTRACT FROM AUTHOR]

Notable cross-country differences exist in the diffusion of the Covid-19 and in its lethality. Contact patterns in populations, and in particular intergenerational contacts, have been argued to be responsible for the most vulnerable, the elderly, getting infected more often and thus driving up mortality in some context, like in the southern European one. This paper asks a simple question: is it between whom contacts occur that matters or is it simply how many contacts people have? Due to the high number of confounding factors, it is extremely difficult to empirically assess the impact of single network features separately. This is why we rely on a simulation exercise in which we counterfactually manipulate single aspects of countries' age distribution and network structures. We disentangle the contributions of the kind and of the number of contacts while holding constant the age structure. More precisely, we isolate the respective effects of inter-age contact patterns, degree distribution and clustering on the virus propagation across age groups. We use survey data on face-to-face contacts for Great Britain, Italy, and Germany, to reconstruct networks that mirror empirical contact patterns in these three countries. It turns out that the number of social contacts (degree distribution) largely accounts for the higher infection rates of the elderly in the Italian context, while differences in inter-age contacts patterns are only responsible for minor differences. This suggests that policies specifically targeting inter-age contacts would be little effective. [ABSTRACT FROM AUTHOR]

This paper investigates the role of children in explaining the life-cycle pattern of consumption (which is hump-shaped since it is higher in the middle of life and lower at the beginning and end of life). Unlike previous studies, a true panel of U.K. households was exploited to investigate whether currently childless households that anticipate having children behave differently from similar households that do not anticipate children. Spending for each group at different ages was estimated using a simple kernel regression. The paper finds that those households that anticipate children, when compared to households that do not anticipate children, do not seem to significantly reduce total spending before having children, nor do they significantly increase total spending after children arrive. Hence, children do not seem to fully explain the hump shape of consumption over the life-cycle. [ABSTRACT FROM AUTHOR]

This paper explains how the spread of Covid-19 in early-2020 led to containment measures throughout Europe, including a legally enforced lockdown in the UK from 23 March which closed most out-of-home leisure provisions. Time use evidence is then used to show how lockdown led to an abrupt, unprecedented in scale, increase in residual 'leisure' time, and how this was distributed and used among males and females, in different age groups. The immediate lessons for leisure studies have been to endorse claims that leisure activities promote well-being, that loss of social connections at work and leisure weakens macro-solidarity, and that the importance of leisure provisions in modern economies. Experiences during the lockdown, and difficulties in existing, then clarify exactly which leisure matters most, for whom, and why. [ABSTRACT FROM AUTHOR]

This paper discusses the role of peer support groups for victims of terrorism and the implications for including this provision in disaster psychosocial planning and response. Peer support here is defined as mutual support by people who have been through the same or similar experience and can help each other through giving emotional and practical support and advocacy. Building on the evidence that social connectedness and peer support are important for trauma relief and recovery, different types of peer support groups are described and are illustrated through two case studies. This paper reviews the creation, facilitation and contribution of two United Kingdom (UK) peer support groups initiated after the 11 September attacks in 2001 and the Paris attacks in 2015. [ABSTRACT FROM AUTHOR]

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In this short paper, I start with a case study – about how elementary school children in the early twentieth century in England understood their responsibilities vis-à-vis family (and school). This example provides a window into a past which deeply contrasts with present-day children's and adults' understandings and lives. I go on to consider (very briefly, for the field is vast) how ideas about childhood changed in the interwar years and how, since then, children have become locked into educational establishments – as well as into families. It seems to me that in these circumstances we are not used to thinking of children as thoughtful and active members of society. So it is no surprise to me that adults do not look to inter-relations with children as key variables towards understanding the social order. I note that my emphasis is on the UK, since I know most about that! [ABSTRACT FROM AUTHOR]

Background: Suicide is the leading cause of death of children and young people under 35 in the UK, and suicide rates are rising in this age group. Schools are considered an appropriate and logical setting for youth suicide prevention activities, with universal, selective, and indicated approaches all demonstrating efficacy. Given that international best practice recommends suicide prevention programmes combine these approaches, and that to date this has not been done in school settings in the UK, this study aims to evaluate the feasibility of delivering a suicide prevention programme incorporating universal, selective, and indicated components in UK schools. Methods: This study is a feasibility cluster-randomised controlled trial (RCT) of an adapted version of the Multimodal Approach to Preventing Suicide in Schools (MAPSS) programme. The programme, initially developed in Australia, involves delivering universal psychoeducation to all pupils, screening them for suicide risk, and delivering Internet-based Cognitive Behavioural Therapy (Reframe IT-UK) to those students identified as being at high-risk for suicide. The programme will be trialled in six secondary schools in Northwest England and will target Year 10 students (14- and 15-year-olds). The primary aims are to assess: 1) the acceptability and safety of delivering MAPSS in a school setting in the UK; 2) the social validity of the MAPSS programme; and 3) the feasibility of delivering a large-scale, appropriately powered, cluster-RCT and economic evaluation of this intervention in the future. Secondary aims are to assess changes over time in mental health and wellbeing outcomes. Discussion: This study is the first to evaluate a suicide prevention programme comprising universal, selective, and indicated components in UK schools. If the programme is found to be feasible, it could be more widely tested in schools and may ultimately lead to reduced rates of suicide and suicidal behaviour in young people. [ABSTRACT FROM AUTHOR]

In contrast to the post-war period, the late 20th and early 21st centuries in the UK have been characterised by the advancement of neoliberal policies including privatisation of the housing system and employment casualisation. Consequently, there are growing socioeconomic inequalities between those born in the post-war period – the 'Baby Boomers' – and the younger generation – the 'Millennials'. Such inequalities have led to narratives of inter-generational conflict with Baby Boomers framed as jeopardising the futures of Millennials. Drawing on Mannheim's theory of social generations, the concept of generational habitus and qualitative data from 49 Baby Boomers and 62 Millennials, we unpack the ways in which inter-generational inequalities are intersubjectively understood and discussed. Our data indicate that while young people are aware of inter-generational inequalities, they do not feel resentful towards their parents' generation for profiting at their expense. Instead, many blame the government for not representing their interests. Thus, narratives of inter-generational conflict misleadingly direct blame towards the agency of Baby Boomers rather than political structures. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic and the lockdown measures imposed as a result affected the lives of people in all parts of society across the world. In 2020, during the first UK national lockdown, older adults (aged 70 years and over) were told to 'shield' within their homes, as they were regarded as being at higher risk of serious COVID-19 infection compared to other age groups. This paper explores older adults' experiences of COVID-19 lockdown measures whilst living in housing with care schemes for older people. The purpose is to examine the impact of the lockdown measures on scheme life including social connections amongst residents and their general everyday wellbeing during this time. We present qualitative findings based on interviews with 72 residents who took part in longitudinal and cross-sectional interviews across 26 housing with care schemes. Data were analysed using a thematic framework approach to examine specifically their experiences of living in housing with care schemes during the 2020 UK lockdown. The paper highlights that COVID-19 restrictions had a detrimental impact on the social connections and interactions of older residents living in housing with care schemes, as well as on their feelings of autonomy and independence. Despite this, residents adapted and coped with self-isolation restrictions and sought out positive ways to maintain social contact with others inside and outside to the scheme. We further highlight the tensions that providers of housing for older adults faced in promoting residents' autonomy and connectedness whilst also trying to provide a safe living environment and protect residents from risk of COVID-19 infection. Our findings apply not only to a pandemic situation but to the broader understanding of how housing with care for older adults must navigate between autonomy and support. • COVID-19 lockdowns challenged the independence and autonomy of older residents of housing with care in the UK. • Older adults in housing with care exercised autonomy through employing practices to maintain social connections. • Housing staff bolstered residents' autonomy, facilitated social interactions, and supported residents' wellbeing. • Housing staff faced challenges in maintaining the independent ethos of housing schemes whilst also protecting residents. [ABSTRACT FROM AUTHOR]

Background: Speech and language therapy provision for aphasia (a language disorder) post stroke has been studied over time through surveys completed by speech and language therapists. This paper revisits provision based on what was received by 278 patients in 21 UK speech and language therapy departments in 2014–2016. Aims: To explore the speech and language therapy received by community dwelling people with post stroke aphasia in the UK. Methods and procedures: A quantitative content analysis was conducted by two speech and language therapist researchers. Therapy goals recorded were coded into categories and subcategories. Descriptive statistics were used to identify the frequency with which goal categories were targeted, average therapy time received, length and frequency of therapy sessions, personnel involved and mode of delivery. Outcomes and results: Forty-five percent of participants were in receipt of therapy in the three month window observed. Six goal categories were identified. Rehabilitation was the most frequent (60%) followed by enabling (17.2%), review (4.3%), assessment (3.6%), supportive (3.5%) and activity to support therapy (2.8%). The median amount of therapy received in three months was 6.3 hours at an average of one 60-minute session every two weeks. Seventy-seven percent of therapy sessions were delivered by qualified speech and language therapists and 23% by assistants. Ninety percent of sessions were one to one, face to face sessions whilst 9.5% were group sessions. Discussion: In line with previous reports, speech and language therapy for community dwelling stroke survivors with aphasia is restricted. Rehabilitation is a large focus of therapy but the intensity and dose with which it is provided is substantially lower than that required for an effective outcome. Despite this, one to one face to face therapy is favoured. More efficient methods to support more therapeutic doses of therapy are not commonly used in routine clinical services. [ABSTRACT FROM AUTHOR]

In 2009, a population level health screening programme was established in the UK for people over the age of 40 years. The primary aim of the service was to identify and treat the leading causes of preventable disease and death, including cardiovascular disease and diabetes. Checks are offered every five years through scheduled appointments at primary care settings, and uptake of such checks has been relatively low to date with 12.7% of those eligible to have a NHS health check receiving one between 2009 and 2013. Non-clinical settings such as sports stadia have previously been used to offer health interventions and opportunistic health checks. Despite relatively modest results in football and rugby settings, professional cricket fixtures with high footfall may offer higher levels of uptake and participant satisfaction, and provide a novel setting for engaging BME communities. This paper describes the process and results from the Boundaries For Life initiative that delivered health checks at professional cricket matches over the 2014 and 2015 seasons. Uptake of the checks was significantly high in comparison to other sports settings, with very strong feedback from participants on the convenience of service. [ABSTRACT FROM AUTHOR]

Mechanisms through which most known Alzheimer's disease (AD) loci operate to increase AD risk remain unclear. Although Apolipoprotein E (APOE) is known to regulate lipid homeostasis, the effects of broader AD genetic liability on non-lipid metabolites remain unknown, and the earliest ages at which metabolic perturbations occur and how these change over time are yet to be elucidated. We examined the effects of AD genetic liability on the plasma metabolome across the life course. Using a reverse Mendelian randomization framework in two population-based cohorts [Avon Longitudinal Study of Parents and Children (ALSPAC, n = 5648) and UK Biobank (n ≤ 118,466)], we estimated the effects of genetic liability to AD on 229 plasma metabolites, at seven different life stages, spanning 8 to 73 years. We also compared the specific effects of APOE ε4 and APOE ε2 carriage on metabolites. In ALSPAC, AD genetic liability demonstrated the strongest positive associations with cholesterol-related traits, with similar magnitudes of association observed across all age groups including in childhood. In UK Biobank, the effect of AD liability on several lipid traits decreased with age. Fatty acid metabolites demonstrated positive associations with AD liability in both cohorts, though with smaller magnitudes than lipid traits. Sensitivity analyses indicated that observed effects are largely driven by the strongest AD instrument, APOE, with many contrasting effects observed on lipids and fatty acids for both ε4 and ε2 carriage. Our findings indicate pronounced effects of the ε4 and ε2 genetic variants on both pro- and anti-atherogenic lipid traits and sphingomyelins, which begin in childhood and either persist into later life or appear to change dynamically. [ABSTRACT FROM AUTHOR]

We investigated the effects of long-term greenspace deprivation on sleep during adolescence. Using data from a UK birth cohort, we studied deviations from age-recommended sleep duration through Time Use Diaries. Our sample (N = 1370; 53% female) of urban adolescents had been exposed to the same levels of neighbourhood greenspace from birth up to age 14 years when their time use was tracked. We factored in sex and ethnicity, family income, long-term illness, sharing of a bedroom, access to a garden, as well as air pollution and perceived area safety. Even after full adjustment, there was a significant interaction between greenspace availability and income when predicting sleep duration, such that low-income adolescents living in the greyest urban areas were found to sleep more than the 8–10 h recommended for their age group, while the inverse was true for their counterparts living in areas with more greenspace. [ABSTRACT FROM AUTHOR]

Purpose: The aim of this article is to identify and compare the social media activity of Generation Z representatives in Poland and Great Britain in the context of customer orientation. Design/methodology/approach: The study was conducted among students in Poland and Great Britain in 2023. The study used a survey method, in particular using the CATI survey technique. Descriptive statistics measures were used to analyze the research data. Findings: The conducted research allowed us to identify the social media portals most frequently visited by Generation Z representatives, as well as the most frequently performed activities towards enterprises. Moreover, the relationship between respondents' answers and their gender and place of residence was examined. In several cases, gender and place of residence significantly differentiated the analyzed variables. The results also allowed us to identify differences in the social media activity of Generation Z representatives in Poland and in Great Britain. Research limitations/implications: The use of survey research is associated with limitations, including: the possibility of superficial knowledge of the studied phenomena, or respondents giving false answers. However, the relatively small number of respondents does not allow the obtained research results to be treated as representative. Future research should be conducted on a larger sample, and quantitative research should be supplemented with qualitative research. Undertaking research in other countries would make it possible to compare the social media activity undertaken by representatives of Generation Z different nationalities and determine whether and which of them occur regardless of geographical location. Practical implications: Understanding the activity of Generation Z representatives in social media will allow organizational employees to adjust their marketing activities to the expectations of this cohort. These activities, the aim of which is to reach the customer, provide him with information about the product, and encourage him to purchase, will ultimately translate into increased sales and profit of the organization. The obtained knowledge indicates that the nationality of respondents is an important factor differentiating activity in social media, which confirms the importance of diversifying marketing activities undertaken by organizations. Originality/value: The article is addressed to employees of organizations responsible for contact with representatives of Generation Z on social media. The presented results complement and deepen knowledge about the activity of Generation Z in social media, including differences in gender and place of residence of the respondent. They also indicate the influence of the nationality of Generation Z respondents on their activity in social media. [ABSTRACT FROM AUTHOR]

In low-cycling countries, cycling is not evenly distributed across genders and age groups. In the UK, men are twice as likely as women to cycle to work and cycling tends to be dominated by younger adults. By contrast, in higher cycling countries and cities, gender differences are low, absent, or in the opposite direction. Such places also lack the UK's steady decline in cycling among those aged over 35 years. Over the past fifteen years some UK local areas have seen increases in cycling. This paper analyses data from the English and Welsh Census 2001 and 2011 to examine whether such increases are associated with greater diversity among cyclists. We find that in areas where cycling has increased, there has been no increase in the representation of females, and a decrease in the representation of older adults. We discuss potential causes and policy implications. Importantly, simply increasing cycling modal share has not proved sufficient to create an inclusive cycling culture. The UK's culturally specific factors limiting female take-up of cycling seem to remain in place, even where cycling has gone up. Creating a mass cycling culture may require deliberately targeting infrastructure and policies towards currently under-represented groups. [ABSTRACT FROM AUTHOR]

The result of the Brexit referendum and its effect on subsequent UK elections have attracted a large amount of media and scholarly interest, but there has been minimal research into gender and voting behaviour at the referendum. Similarly, gendered differences in Euroscepticism have had little attention. This article seeks to understand how attitudes towards the European Union vary by age and gender and whether such gender-age gaps are associated with gender differences in attributes known to predict European Union attitudes and support for Leave/Remain. The article finds a gender gap in Euroscepticism in under-45s and in Brexit vote choice in under-25s. It demonstrates that socioeconomic and value differences by gender are associated with the gender gap in younger age groups, but not older. As such differences seem likely to persist, this article suggests that gender divides will continue to have electoral and democratic consequences in the United Kingdom and across Europe. [ABSTRACT FROM AUTHOR]

Mathematical and statistical models can be used to make predictions of how epidemics may progress in the near future and form a central part of outbreak mitigation and control. Renewal equation based models allow inference of epidemiological parameters from historical data and forecast future epidemic dynamics without requiring complex mechanistic assumptions. However, these models typically ignore interaction between age groups, partly due to challenges in parameterising a time varying interaction matrix. Social contact data collected regularly during the COVID-19 epidemic provide a means to inform interaction between age groups in real-time. We developed an age-specific forecasting framework and applied it to two age-stratified time-series: incidence of SARS-CoV-2 infection, estimated from a national infection and antibody prevalence survey; and, reported cases according to the UK national COVID-19 dashboard. Jointly fitting our model to social contact data from the CoMix study, we inferred a time-varying next generation matrix which we used to project infections and cases in the four weeks following each of 29 forecast dates between October 2020 and November 2021. We evaluated the forecasts using proper scoring rules and compared performance with three other models with alternative data and specifications alongside two naive baseline models. Overall, incorporating age interaction improved forecasts of infections and the CoMix-data-informed model was the best performing model at time horizons between two and four weeks. However, this was not true when forecasting cases. We found that age group interaction was most important for predicting cases in children and older adults. The contact-data-informed models performed best during the winter months of 2020–2021, but performed comparatively poorly in other periods. We highlight challenges regarding the incorporation of contact data in forecasting and offer proposals as to how to extend and adapt our approach, which may lead to more successful forecasts in future. Author summary: Short term epidemic forecasts help policy makers to plan and implement response activities. It can be useful to have such forecasts separately for different age groups, in order to reflect potential differences in transmission and incidence of infection between age groups as well as differences in risk of severe disease or death. A key challenge in developing age-specific models is understanding how different age-groups interact. We used data collected during a large-scale weekly survey of social contacts in the UK to inform this interaction in a model for short-term forecasts of COVID-19. To assess whether allowing interaction between age-groups and the use of contact data improved forecasts, we compared our forecasts to those from a set of models that either didn't use current contact data or treated each age group as a separate population. We found that including timely contact data improved predictions when forecasting two to four weeks into the future, but this improvement was not consistent throughout the epidemic. The best improvement was measured during a long national "lockdown". We also found that inclusion of age-group interaction and use of contact data were most important when forecasting infections in older adults and young children. [ABSTRACT FROM AUTHOR]

Purpose: To extend existing analyses of whether and how the age of respondents is related to their time trade-off (TTO) valuations of hypothetical EQ-5D-3L health states, and to contribute to the existing debate about the rationale and implications for using age-specific utilities in health technology assessment (HTA).Methods: We use data from the MVH UK valuation study. For each profile, the mean TTO value-adjusted by sex, education, self-reported health and personal experience of serious illness-is pairwise compared across the different age groups. A Bonferroni correction is applied to the multiple testing of significant differences between means. Smile plots illustrate the results. A debate regarding whether there is a case for using age-specific utilities in HTAs complements the analysis.Results: Results show that the oldest respondents value health profiles lower than younger age groups, particularly for profiles describing problems in the mobility dimension.Conclusion: The findings raise the possibility of using age-specific value sets in HTAs, since a technology may not be cost-effective on average but cost-effective for a sub-group whose preferences are more closely aligned to the benefits offered by the technology. [ABSTRACT FROM AUTHOR]

Purpose: Ransomware is a relatively new form of financial extortion that is proving a major cyber-security threat to individuals and organisations. This study aims to investigate factors that may influence an individual's willingness to engage in a ransom payment. Design/methodology/approach: This study ran a large survey (n = 1,798) on a representative sample of the UK population. This study elicited willingness to pay (WTP) ransomware and also reasons for not wanting to pay a ransom to criminals. This study then used non-parametric tests and regression analysis to identify factors that influence WTP. Findings: This study finds that women and younger age groups are significantly more willing to pay a ransom, as are those who store photos. There is a strong positive relationship between concern for data breach and WTP a ransom. Originality/value: To the best of the authors' knowledge, this is the first large scale study to look at WTP ransomware. This study identifies a range of factors that can help inform law enforcement to target advice about ransomware attacks. [ABSTRACT FROM AUTHOR]

Purpose: Existing evidence on the relationship between mode of delivery and offspring emotional and behavioural problems, especially in older age groups, is limited and inconsistent. This study aimed to examine the association between obstetric mode of delivery and emotional and behavioural problems in offspring aged 3–16 years. Methods: The sample for this study comprised participants in the Avon Longitudinal Study of Parents and Children (ALSPAC) in the United Kingdom. The study cohort ranged from 7074 (at 3 years of age) to 4071 (at 16 years of age) mother–offspring pairs. Data on obstetric mode of delivery were abstracted from obstetric records by trained research midwives and classified as spontaneous vaginal delivery, assisted vaginal delivery and caesarean delivery (elective and emergency). Offspring emotional and behavioural problems were measured using the Strengths and Difficulties Questionnaire (SDQ) when the child was 3, 7, 9, 11, and 16 years. Logistic regression analyses were used to examine associations. Results: Assisted vaginal delivery was associated with an increased risk of emotional problems at age 11 years (OR = 1.42; 95% CI 1.11–1.81). No significant associations were observed at ages 3, 7, 9 and 16. We found no evidence of associations between caesarean delivery (elective or emergency) and emotional and behavioural measures in offspring across all age groups. Conclusion: Mode of delivery does not appear to be associated with emotional and behavioural problems in children and adolescents. Further research is needed to understand the potential longer-term effects of assisted vaginal deliveries on offspring emotional development. [ABSTRACT FROM AUTHOR]

This study investigates whether the perception–production link in phonological acquisition varies with stages of L2 development. It also examines whether the perception–production link for L2 vowels varies according to vowel properties, or whether the L2 vowels match or mismatch with L1 vowels. Korean learners of English in the UK were divided into more experienced and less experienced groups based on age of arrival and length of residence. The learners completed English vowel production, English vowel identification, and English–Korean vowel mapping tasks with English words (e.g., beat, bot). The intelligibility of their production and the accuracy of their vowel identification were assessed. Results show that only the more experienced learners' perception and production were significantly correlated. Among L2 Standard Southern British English vowels similar to L1 Korean vowels (/i, ʌ, u/) only /i/ showed a significant correlation between perception and production, while among L2 vowels dissimilar to L1 vowels (/eɪ, ɘʊ, ɑ, ɒ/) only /ɑ/ showed a negative correlation, indicating that the correlation varied with vowel properties. The study contributes to the L2 phonological acquisition literature by exploring the perception–production link in terms of different stages of L2 development and L2 vowel properties. [ABSTRACT FROM AUTHOR]

The study aimed to investigate the association between interpregnancy interval (IPI) and parent-reported oppositional defiant disorder (ODD) in offspring at 7 and 10 years of age. We used data from the Avon Longitudinal Study of Parents and Children (ALSPAC), an ongoing population-based longitudinal study based in Bristol, United Kingdom (UK). Data included in the analysis consisted of more than 3200 mothers and their singleton children. The association between IPI and ODD was determined using a series of log-binomial regression analyses. We found that children of mothers with short IPI (<6 months) were 2.4 times as likely to have a diagnosis of ODD at 7 and 10 years compared to mothers with IPI of 18–23 months (RR = 2.45; 95%CI: 1.24–4.81 and RR = 2.40; 95% CI: 1.08–5.33), respectively. We found no evidence of associations between other IPI categories and risk of ODD in offspring in both age groups. Adjustment for a wide range of confounders, including maternal mental health, and comorbid ADHD did not alter the findings. This study suggests that the risk of ODD is higher among children born following short IPI (<6 months). Future large prospective studies are needed to elucidate the mechanisms explaining this association. [ABSTRACT FROM AUTHOR]

This study aimed to assess the trajectory of wellbeing and psychological distress in a UK sample by comparing data taken from the first and second UK lockdowns. Wellbeing (indexed via the Warwick-Edinburgh Mental Wellbeing Scale) and psychological distress (indexed via the K10) were measured in two surveys in large online samples from Wales, UK. The first survey (n = 12,989) took place 11–16 weeks into the first UK lockdown and the second survey (n = 10,428) took place 4–11 weeks into the second UK lockdown. Levels of wellbeing were lower in the second survey compared to the first survey, which were already low compared to pre-pandemic data (2019). Clinically significant levels of psychological distress were found in 40.4% of participants in the second survey, representing a 9.8% increase in prevalence from the first survey. Poorer mental health was found in women, younger adults, and those from deprived areas. The greatest reduction in mental health was found in the youngest age group (16-24 years old). The COVID-19 pandemic and the measures taken to curb its spread continue to negatively impact the wellbeing of the UK population. [ABSTRACT FROM AUTHOR]

The five-dimensional curiosity-scale revised (5DCR) by Kashdan et al. (2020) is the most comprehensive curiosity inventory available to date. 5DCR measures six facets of curiosity with four items each. Here, we present a German-language adaptation of the 5DCR and comprehensively validate this adaptation in a diverse sample of adults from Germany (N = 486). Moreover, we provide new evidence on the original English-language 5DCR in a parallel sample from the UK (N = 483). In both countries, we investigate the six facets' reliability, factorial validity, and convergent and discriminant validity with a large set of individual-differences constructs. In addition, we analyze the measurement invariance of the curiosity facets across the UK and Germany and across socio-demographic subgroups defined by age, sex, and education. Findings demonstrate that the new German-language adaptation of 5DCR and its English-language source version show psychometric properties similar to the original studies by Kashdan et al. (2020) in the United States. All six curiosity facets reach at least partial scalar invariance across cultures, sex, education, and mostly also across age groups. The findings support the six-faceted theory of curiosity and show that 5DCR allows for a valid assessment of curiosity across cultures. [ABSTRACT FROM AUTHOR]

This paper aims to assess the vulnerability of coastal areas to sectoral pressures from maritime-related socio-economic activities. To do this, a DEA-based method is proposed to construct a synthetic index of anthropogenic vulnerability with which to rank European Atlantic Area countries and regions down to a regional scale below the national level. The set of indicators selected for this index focuses on five important vectors: marine spills, port activities, tourism, protection of natural areas, and water quality and waste management. The paper shows that, overall, the United Kingdom has the most vulnerable coast in Atlantic Europe, with Ireland showing the most resilient coast of all. Furthermore, the proposed method also allows one to identify peer groups with the same vulnerability pattern. Thus, policies aiming to reduce the vulnerability of a target region may be devised by focusing on the least vulnerable regions within the relevant group. The detailed analysis presented may help regional policy makers as a diagnostic tool to detect and assess vulnerability weaknesses so that they can design and carry out appropriate actions in line with integrated European coastal management policies. • Data Envelopment Analysis-based method allows for flexible weights. • Synthetic index scores rank regions according to maritime-related coastal pressures. • United Kingdom has the most vulnerable coast and Ireland the least. • Index identifies peer groups with the same vulnerability pattern. • Regional policymakers can use it as diagnostic tool to design management actions. [ABSTRACT FROM AUTHOR]

Social media is lauded as a powerful tool for informal learning, and a tool of choice for teenagers. This paper reports on the findings of a survey of 384 secondary school pupils in the UK (aged 11-17) over a 12 week period. Our findings indicate a pervasiveness of social media usage amongst this age group, hut variety in the types of engagement and selfreported importance of social media. Usage of social media for learning is dominated by logistical task support (for example, clarifying instructions) and heavily focused around homework activities. However, it appears that this provides a context for deeper engagement and learning around those homework activities. Our findings indicate that social media is being used by this age group to support their learning, but that there is still great untapped potential both in terms of the range of activities discussed, and the number of pupils engaging. [ABSTRACT FROM AUTHOR]

Acute hepatitis has always been a public health concern, but the recent clustering of cases in various parts of the world has drawn some special attention. The sudden rise in cases has mainly been among the pediatric population of around 35 countries around the world, including developed countries such as the United States, the United Kingdom, and European countries. The outbreaks have had a devastating impact, with around 10% of the affected patients developing liver failure. The clinical presentation of patients resembles any other case of acute hepatitis, with the major symptoms being: jaundice (68.8%), vomiting (57.6%), and gastrointestinal symptoms such as abdominal pain (36.1%) and nausea (25.7%). Interestingly, the cases have tested negative for hepatotropic viruses Hep A, B, C, and E, thus giving rise to the terms Hepatitis of Unknown Origin or non-HepA–E hepatitis. Many causes have been attributed to the disease, with major evidence seen for adenovirus and SARS-CoV-2. International agencies have stressed on establishing diagnostic and management protocols to limit these outbreaks. As the understanding has evolved over time, diagnostic and management faculties have found more shape. The current review was designed to comprehensively compile all existing data and whittle it down to evidence-based conclusions to help clinicians. [ABSTRACT FROM AUTHOR]

This article examines the association between partisanship and vaccination in the UK. The lower vaccination rates among Republicans in the US have been linked to ideology and President Trump's anti-vaccination rhetoric. By contrast, both ruling and opposition parties in the UK promoted the national vaccination program. Using two datasets at constituency and individual levels, we analyse whether there are partisan differences in uptake when vaccination garners cross-party support. Our findings contrast in important ways from the US case. First, the correlation between partisanship and vaccination is the opposite to that of the US: both Conservative constituencies and individuals are associated with higher vaccination rates than Labour across almost all age groups. Thus, right-leaning individuals do not necessarily vaccinate less, at least when their political party is in power and supportive of vaccination. Second, partisanship alone accounts for a large share of variation in vaccination rates, but this association appears largely driven by socio-economic and demographic differences: older and economically better off individuals and constituencies tend to be more vaccinated. Once these controls are included, the correlation between Conservative partisanship and vaccination shrinks substantially. Hence, the ideological source of the partisan gap in vaccination rates appears smaller than in the US. [ABSTRACT FROM AUTHOR]

Background: People aged over 50 years form a growing proportion of the working age population, but are at increased risk of unemployment compared to other age groups. It is often difficult to return to work after unemployment, particularly for those with health issues. In this paper, we explored the perceptions, attitudes, and experiences of returning to work after a period of unemployment (hereafter RTW) barriers among unemployed adults aged over 50 years.Method: In-depth semi-structured interviews were conducted with a diverse sample of 26 unemployed individuals aged 50-64 years who were engaged with the UK Government's Work Programme. Data were thematically analysed.Results: Age alone was not discussed by participants as a barrier to work; rather their discussions of barriers to work focused on the ways in which age influenced other issues in their lives. For participants reporting chronic health conditions, or disabilities, there was a concern about being unfit to return to their previous employment area, and therefore having to "start again" in a new career, with associated concerns about their health status and managing their treatment burden. Some participants also reported experiencing either direct or indirect ageism (including related to their health status or need to access healthcare) when looking for work. Other issues facing older people included wider socio-political changes, such as the increased pension age, were felt to be unfair in many ways and contradicted existing expectations of social roles (such as acting as a carer for other family members).Conclusion: Over-50s experienced multiple and interacting issues, at both the individual and societal level, that created RTW barriers. There is a need for employability interventions that focus on supporting the over-50s who have fallen out of the labour market to take a holistic approach, working across healthcare, employability and the local labour market, providing treatment and skills training for both those out of work and for employers, in order to create an intervention that that helps achieve RTW and its associated health benefit. [ABSTRACT FROM AUTHOR]

Objective: This study uses three linked datasets to provide an estimate of incidence of motor neuron disease (MND) in England from 1998 to 2019. Comparison is made to previous British studies. It examines age at diagnosis and ethnicity of those affected. Methods: The literature was searched for studies of MND incidence in Great Britain from 1995 to date. The QResearch and linked Hospital Episode Statistics and Death register databases were searched from 1998 to 2019 for cases of MND, and incidence calculated from 16.8 million adults and 112 million adult years of data. Results: We found 6437 adults with a diagnosis of MND giving an incidence of MND of 5.69/100,000 person years (95% CI 5.51–5.88); 6.57 (6.41–6.99) in men and 4.72 (4.49–4.97) in women when age-standardized to the 2011 UK population. The median age of diagnosis was 72 years. Peak incidence occurred in the 80–84 year age group in men and 75–79 in women. Age-standardized incidence was as high in Bangladeshi, Black Caribbean, Indian, other Asian and Pakistani people as in White people. Black African and Chinese people had a lower incidence. Conclusion: The use of three linked national datasets captured 33% more people than a primary care dataset alone. Patients were older than in previous studies and rates were high in all ethnic groups studied except Black African and Chinese people. We present the highest incidence of MND reported globally in the past 50 years. Methodological differences may in part explain differences with previous reports. The use of national datasets may have captured additional MND patients with serious comorbidities who have not seen a neurologist before death. A limitation of this approach is that unlike population registers, which minimize false positive diagnosis by neurologist review of each patient, we cannot review diagnosis for individuals as data are anonymized. [ABSTRACT FROM AUTHOR]

Social cognition refers to a broad range of cognitive processes and skills that allow individuals to interact with and understand others, including a variety of skills from infancy through preschool and beyond, e.g., joint attention, imitation, and belief understanding. However, no measures examine socio-cognitive development from birth through preschool. Current test batteries and parent-report measures focus either on infancy, or toddlerhood through preschool (and beyond). We report six studies in which we developed and tested a new 21-item parent-report measure of social cognition targeting 0–47 months: the Early Social Cognition Inventory (ESCI). Study 1 (N = 295) revealed the ESCI has excellent internal reliability, and a two-factor structure capturing social cognition and age. Study 2 (N = 605) also showed excellent internal reliability and confirmed the two-factor structure. Study 3 (N = 84) found a medium correlation between the ESCI and a researcher-administered social cognition task battery. Study 4 (N = 46) found strong 1-month test–retest reliability. Study 5 found longitudinal stability (6 months: N = 140; 12 months: N = 39), and inter-observer reliability between parents (N = 36) was good, and children's scores increased significantly over 6 and 12 months. Study 6 showed the ESCI was internally reliable within countries (Australia, Canada, United Kingdom, United States, Trinidad and Tobago); parent ethnicity; parent education; and age groups from 4–39 months. ESCI scores positively correlated with household income (UK); children with siblings had higher scores; and Australian parents reported lower scores than American, British, and Canadian parents. [ABSTRACT FROM AUTHOR]

SARS-COV-2 is a deadly virus which emerged in China in late 2019. In this article, the difference in European variant (2nd wave) and UK variant (3rd wave) of COVID-19 in Pakistan was investigated. Polymerase chain reaction (PCR) technique was applied to evaluate the difference in gene sequence of both the variants. The UK variant (3rd wave) was more terrible due to its resistance and genomic mutation. When performed PCR in both the waves, there was nucleocapsid protein (N gene) in UK variant while envelop protein (E) was more prominent in European variant after ORF 1ab in both the strains. People of all age groups were tested and was reported that aged individuals were at more risk of infection as compared to young ones. Similarly females were having more immunity in defence against COVID-19 infection as compared to males that increased more risk of infection to them. [ABSTRACT FROM AUTHOR]

In 2002, Diabetic Retinopathy was reported as the leading cause of blindness in the working age group. The introduction of systematic screening programs in the UK has reduced visual loss and blindness due to diabetic retinopathy, but it does still occur with catastrophic consequences for the individual. The author conducted an ongoing search for articles relating to diabetic retinopathy since 2000 utilizing Zetoc Alert with keywords and contents page lists from relevant journals. This review covers the risk factors for loss of vision due to diabetic retinopathy and discusses ways in which the awareness of these risk factors can be used to further reduce visual loss. Some risk factors such as glycemic and B/P control are well known from landmark trials. This review has included these factors but concentrated more on the evidence behind those risk factors that are not so clearly defined or so well known. The major risk factors are well known, but one continues to find that people with diabetes lose vision in situations in which a better awareness of the risks by both the individual with diabetes and the health workers involved may have prevented the visual loss. [ABSTRACT FROM AUTHOR]

Objective: This study provides Dutch national norms for the parent-reported Strengths and Difficulties Questionnaire (SDQ) for children aged 3-14 years, and assesses the test performance of the SDQ Total Difficulties Scale (TDS) and impairment Scale. We further compared Dutch SDQ norms with those of the United Kingdom (UK), to determine potential variation in country-specific norms.Study Design: We analyzed data of 3384 children aged 3 to 14 years. The data were obtained in schools, and in the context of Preventive Child Healthcare. Parents completed the SDQ parent form and the Child Behavior Checklist (CBCL). We determined clinical (10% elevated scores) and borderline (20% elevated scores) SDQ TDS norms. We assessed the test performance (validity) of the SDQ TDS and Impairment Score using the CBCL as criterion.Results: The clinical SDQ TDS norms varied between > 10 and > 14 depending on the age group. The SDQ TDS discriminated between children with and without problems, as measured by the CBCL, for all age groups (AUCs varied from 0.92 to 0.96). The SDQ Impairment Score had added value (beyond the SDQ TDS) only for the age group 12-14 years. For the Netherlands we found lower clinical SDQ TDS norms than those previously reported for the UK (i.e. > 16).Conclusion: The clinical SDQ TDS norms varied between > 10 and > 14 depending on the age groups. We found good test performance at these proposed norms. Dutch norms differed somewhat from UK norms. In the Netherlands, the SDQ performed better with Dutch-specific norms than with UK-specific norms. [ABSTRACT FROM AUTHOR]

Objective: Front-of-pack (FOP) nutrition labelling is a globally recommended strategy to encourage healthier food choices. We evaluated the effect of FOP labels on the perceived healthfulness of a sweetened fruit drink in an international sample of adult consumers.Design: Six-arm randomised controlled experiment to examine the impact of FOP labels (no label control, Guideline Daily Amounts (GDA), Multiple Traffic Lights, the Health Star Ratings (HSR), Health Warning Labels, and 'High-in' Warning Labels (HIWL)) on the perceived healthfulness of the drink. Linear regression models by country examined healthfulness perceptions on FOP nutrition labels, testing for interactions by demographic characteristics.Setting: Online survey in 2018 among participants from Australia, Canada, Mexico, United Kingdom (UK) and United States.Participants: Adults (≥18 years, n 22 140).Results: Compared with control, HIWL had the greatest impact in lowering perceived healthfulness (β from -0·62 to -1·71) across all countries. The HIWL and the HSR had a similar effect in Australia. Other labels were effective in decreasing the perceived healthfulness of the drink within some countries only, but to a lower extent. The GDA did not reduce perceived healthfulness in most countries. In the UK, the effect of HIWL differed by age group, with greater impact among older participants (> 40 years). There were no other variations across key demographic characteristics.Conclusions: HIWL, which communicates clear, non-quantitative messages about high levels of nutrients of concern, demonstrated the greatest efficacy to decrease the perceived healthfulness of a sweetened fruit drink across countries. This effect was similar across demographic characteristics. [ABSTRACT FROM AUTHOR]