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Micro surface defects (SDs) would be unavoidably induced on most fused silica surfaces (FSSs), substantially reducing their laser-induced damage thresholds (LIDTs). There is still no clear understanding of the relation between SD structural feature and their LIDTs, which poses a challenge to the recognition and mitigation of the dangerous SDs with low LIDTs in industrial production. In this work, the brittle-plasticity and stress states of the SDs are found to dominate the atomic point-defect densities on FSSs and resultantly dominate their LIDTs for the first time. Based on this, the SDs have been divided into four categories: pressure-induced brittle defects (PBDs), pressure-induced plastic defects (PPDs), tension-induced brittle defects (TBDs) and tension-induced plastic defects (TPDs). Based on the tested LIDTs, laser damage morphologies and photoluminescence (PL) characteristics, the laser damage resistance of different kinds of SDs are compared, whose reasons are revealed on the basis of the molecular dynamics (MD) simulations. The sharp increase of the atomic point-defect density from the plasticity to the brittleness of the material, the significant disparity in tensile and compressive strength of fused silica, the distinctly different material response behaviours under tensile and compressive forces, as well as the opposite effects of the tensile and compressive forces on the material compactness significantly affect the atomic point-defect densities on FSSs and resultantly contribute to the different laser damage resistance of different kinds of SDs. This work possesses great significance in solving the laser damage on FSSs. It could also provide a new understanding of the impact of the tensile and compressive forces on the LIDTs of various optical elements. [ABSTRACT FROM AUTHOR]