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Employees' ability to explore and exploit is a micro-foundational component of organizational ambidexterity and hugely influential for organizational performance outcomes. However, little research has directly examined the relationship between exploration and exploitation with a performance at the individual-level. Building on the hierarchical dynamic capability perspective of ambidexterity, we investigate how employee exploration and exploitation affect task performance. We argue that employees' ability to explore enhances task performance through employee exploitation. Furthermore, drawing on the strategic fit perspective, we examine how this employee exploration-exploitation-task performance relationship varies across different levels of organizational competitive orientation. Using a sample of 278 employees from three IT companies in China, our findings demonstrate that both employee exploration and exploitation have a positive effect on task performance, and employee exploitation acts as an effective mechanism which partially explains the relationship between employee exploration and task performance. Notably, we also find that the path relationship of employee exploration-exploitation-task performance is stronger when competitive orientation is low rather than high. Theoretical and managerial implications of these findings are discussed. [ABSTRACT FROM AUTHOR]

Researchers have traditionally distinguished leaders by the extent to which they are oriented to people and productivity, and meta-analytic results indicate that these orientations have consistent and practically important effects. But research is needed to understand the dynamics by which these orientations induce team effectiveness. This study empirically relates leader orientations to teamwork by suggesting that productivity- and people-oriented leaders develop cooperative goals among team members that in turn results in team effectiveness. A total of 146 team leaders from 21 organizations in China completed measures of productivity and people orientations and their encouraging cooperative goals among team members; 1067 team members rated their effectiveness. Results of the structural equation analysis support the theorizing that leader productivity and people values when complemented by strengthening cooperative relationships can contribute to making teams effective in China and perhaps in other countries as well. [ABSTRACT FROM AUTHOR]

Background: Cell-free fetal DNA (cffDNA) has opened up new approaches for non-invasive prenatal testing (NIPT), and it is often used as the second-tier test for high-risk pregnant women in detecting trisomy (T) 21, T18, and T13 after serum biochemistry screening. This study aims to discuss the clinical performance of NIPT as an alternative first-tier screening test for pregnant women in detecting T21, T18, T13, and sex chromosome aneuploidies (SCAs) in China., Methods: A total of 42,924 samples were recruited. The cell-free plasma DNA was directly sequenced. Each of the chromosome aneuploidies of PPV was analyzed. A total of 22 placental samples were acquired, including 14 FP and 8 TP samples. The placental verification of FP NIPT results was performed., Results: Among 42,924 samples, 281 (0.65%) positive cases, including 87 of T21, 31 of T18, 22 of T13, and 141 of SCAs were detected. For the detection of T21, the positive predictive value (PPV) was 78.46%, for trisomy 18, 62.96%, for trisomy 13, 10.00%, for SCAs, 47.22% in the total samples. For trisomy 21, the PPV was 86.67%, for trisomy 18, 80.00%, for trisomy 13, 20.00%, for SCAs, 56.52% in advanced maternal age (AMA) women. The PPV of T21 increased with age. For T18, the PPV showed an overall upward trend. For T13 and SCAs, PPV was raised first and then lowered. Placental verification of false positive (FP) NIPT results confirmed confined placental mosaicism(CPM) was the reason for false positives., Conclusions: This study represents the first time that NIPT has been used as a first-tier screening test for fetal aneuploidies in a pilot city with large clinical samples in China. We propose that NIPT could replace serum biochemistry screening as a first-tier test.