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129 results on '"Ahn, Young Hwan"'

7. Effects of 4G Long-Term Evolution Electromagnetic Fields on Thyroid Hormone Dysfunction and Behavioral Changes in Adolescent Male Mice.

Author

Kim, Hyun-Yong, Son, Yeonghoon, Jeong, Ye Ji, Lee, Soo-Ho, Kim, Nam, Ahn, Young Hwan, Jeon, Sang Bong, Choi, Hyung-Do, and Lee, Hae-June

Subjects
LEAD exposure, GENE expression, LONG-Term Evolution (Telecommunications), THYROID hormones, ENDOCRINE system
Abstract

Radiofrequency electromagnetic fields (RF-EMFs) can penetrate tissues and potentially influence endocrine and brain development. Despite increased mobile phone use among children and adolescents, the long-term effects of RF-EMF exposure on brain and endocrine development remain unclear. This study investigated the effects of long-term evolution band (LTE) EMF exposure on thyroid hormone levels, crucial for metabolism, growth, and development. Four-week-old male mice (C57BL/6) were exposed to LTE EMF (whole-body average specific absorption rate [SAR] 4 W/kg) or a positive control (lead; Pb, 300 ppm in drinking water) for 4 weeks. Subsequently, the mice underwent behavioral tests including open field, marble burying, and nest building. Blood pituitary and thyroid hormone levels, and thyroid hormone-regulating genes within the hypothalamus–pituitary–thyroid (HPT) axis were analyzed. LTE exposure increased T3 levels, while Pb exposure elevated T3 and T4 and decreased ACTH levels. The LTE EMF group showed no gene expression alterations in the thyroid and pituitary glands, but hypothalamic Dio2 and Dio3 expressions were significantly reduced compared to that in the sham-exposed group. Pb exposure altered the hypothalamic mRNA levels of Oatp1c1 and Trh, pituitary mRNA of Trhr, and Tpo and Tg expression in the thyroid. In conclusion, LTE EMF exposure altered hypothalamic Dio2 and Dio3 expression, potentially impacting the HPT axis function. Further research is needed to explore RF-EMF's impacts on the endocrine system. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Current status of ultrasonography in national cancer surveillance program for hepatocellular carcinoma in South Korea: a large-scale multicenter study

Author

Yoo, Sun Hong, primary, Kim, Soon Sun, additional, Kim, Sang Gyune, additional, Kwon, Jung Hyun, additional, Lee, Han-Ah, additional, Seo, Yeon Seok, additional, Jung, Young Kul, additional, Yim, Hyung Joon, additional, Song, Do Seon, additional, Kang, Seong Hee, additional, Kim, Moon Young, additional, Ahn, Young-Hwan, additional, Han, Jieun, additional, Kim, Young Seok, additional, Chang, Young, additional, Jeong, Soung Won, additional, Jang, Jae Young, additional, and Yoo, Jeong-Ju, additional

Published
2023
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24. An International Collaborative Animal Study of the Carcinogenicity of Mobile Phone Radiofrequency Radiation: Considerations for Preparation of a Global Project

Author

Ahn, Young Hwan, primary, Imaida, Katsumi, additional, Kim, Yong‐Bum, additional, Han, Kang‐Hyun, additional, Pack, Jeong‐Ki, additional, Kim, Nam, additional, Jeon, Sang Bong, additional, Lee, Ae‐Kyoung, additional, Choi, Hyung Do, additional, Wang, Jianqing, additional, Kawabe, Mayumi, additional, and Kim, Hye Sun, additional

Published
2022
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25. Risk Prediction Model Based on Magnetic Resonance Elastography-Assessed Liver Stiffness for Predicting Posthepatectomy Liver Failure in Patients with Hepatocellular Carcinoma

Author

Cho, Hyo Jung, primary, Ahn, Young Hwan, additional, Sim, Min Suh, additional, Eun, Jung Woo, additional, Kim, Soon Sun, additional, Kim, Bong Wan, additional, Huh, Jimi, additional, Lee, Jei Hee, additional, Kim, Jai Keun, additional, Lee, Buil, additional, Cheong, Jae Youn, additional, and Kim, Bohyun, additional

Published
2022
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26. Effects of intermediate frequency electromagnetic fields: a review of animal studies.

Author

Lee, Hae-June, Jin, Hee, Ahn, Young Hwan, Kim, Nam, Pack, Jeong Ki, Choi, Hyung-Do, and Lee, Yun-Sil

Subjects
ELECTROMAGNETIC fields, WIRELESS power transmission, PSYCHONEUROIMMUNOLOGY, EXPOSURE therapy, GENE expression, RISK assessment
Abstract

Many novel devices such as induction cookers or wireless power transfer produce electromagnetic fields (EMFs) in the intermediate frequency (IF) range (300 Hz to 10 MHz) and it is very meaningful for summarizing the bioeffects of IF-EMF research, particularly animal studies. This review takes into account experimental studies that used murine models to study the health effects of exposure to IF-EMF. The analyses included here use data available in the literature published from January 1988 to August 2021 including the animal studies about general adverse effects, tumorigenic effects, and effects on developmental stages. The studies that linked IF-EMF exposure during pregnancy or neonatal stage to behavioral and cognition changes were included. Additionally, this review also covers the effects of IF-EMF on gene expression patterns in the brain, behavior patterns associated with learning and memory, and immune function. Although most studies have suggested that IF-EMF is harmless, some adverse effects have been reported after exposure at developmental stages and prolonged exposure. Compared to extremely low frequency (ELF) or radiofrequency (RF) EMF bands, studies on health effects with more diverse perspectives of IF-EMF have not been conducted. Therefore, performing more research should be necessary using the latest biomedical tools. From this point of view, a comprehensive review of IF-EMF studies, particularly animal studies, will provide a valuable basis for further risk analysis in humans. [ABSTRACT FROM AUTHOR]

Published
2023
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28. Independent Risk Factors for Mortality in Patients with Chronic Obstructive Pulmonary Disease Who Undergo Comprehensive Cardiac Evaluations

Author

Ahn, Young-Hwan, Lee, Keu Sung, Park, Joo Hun, Jung, Jin-Hee, Lee, Miyeon, Jung, Yun-Jung, Chung, Wou Young, Sheen, Seungsoo, Park, Kwang Joo, Kim, Dae Jung, Kang, Dae Ryoung, Lee, Jeong-Dong, Yoon, Soojee, Jin, Xiong Jie, Yang, Hyoung-Mo, Lim, Hong-Seok, Park, Jin Sun, Shin, Joon-Han, and Tahk, Seung-Jea

Published
2015
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32. Independent Risk Factors for Hepatocellular Carcinoma Recurrence after Direct-Acting Antiviral Therapy in Patients with Chronic Hepatitis C

Author

Ahn, Young-Hwan, primary, Lee, Heirim, additional, Kim, Do Young, additional, Lee, Hye Won, additional, Yu, Su Jong, additional, Cho, Young Youn, additional, Jang, Jeong Won, additional, Jang, Byoung Kuk, additional, Kim, Chang Wook, additional, Kim, Hee Yeon, additional, Park, Hana, additional, Cho, Hyo Jung, additional, Park, Bumhee, additional, Kim, Soon Sun, additional, and Cheong, Jae Youn, additional

Published
2021
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45. Influences of exposure to 915-MHz radiofrequency identification signals on serotonin metabolites in rats: a pilot study.

Author

Kim, Hye Sun, Paik, Man-Jeong, Seo, Chan, Choi, Hyung Do, Pack, Jeong-Ki, Kim, Nam, and Ahn, Young Hwan

Subjects
SEROTONIN, RADIO frequency, RATS, PILOT projects, METABOLITES
Abstract

The influences of radiofrequency electromagnetic exposure on animal health, particularly on serotonin metabolism, are not well-elucidated. In this in vivo study, we studied the influences of exposure to radiofrequency identification (RFID) signals on serotonin metabolism. Twenty-two male Sprague–Dawley rats were assigned to sham (n = 10) and RFID-exposed (n = 12) groups. Rats in the RFID-exposed group were exposed to RFID signals at an average whole-body specific absorption rate of 2 W/kg for 8 h/day, 5 days/week for 2 weeks. Before and after RFID exposure, 24-h urine was collected from each rat. Urinary tryptophan, 5-hydroxytryptophan, serotonin, 5-hydroxyindoleacetic acid, and 5-methoxyindole-3-acetic acid concentrations were examined using gas chromatography-mass spectrometry, and changes in the patterns of values were compared between the two groups. Urinary levels of serotonin decreased by 20% (p =.041, Student's t-test) and 40% (p =.024, Student's t-test) in both the sham and RFID-exposed groups, respectively. The level of 5-methoxyindole-3-acetic acid decreased by 30% in the RFID-exposed group (p =.039, Student's t-test). Our results indicate that exposure to RFID signals at a specific absorption rate of 2 W/kg is sufficient to alter serotonin metabolism in rats regardless of whether the exposure level is considered biohazardous. [ABSTRACT FROM AUTHOR]

Published
2021
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47. Thrombocytopenia in Systemic Lupus Erythematosus

Author

Jung, Jin-Hee, Soh, Moon-Seung, Ahn, Young-Hwan, Um, Yoo-Jin, Jung, Ju-Yang, Suh, Chang-Hee, and Kim, Hyoun-Ah

Subjects
Adult, Male, Remission Induction, Observational Study, Middle Aged, Prognosis, Severity of Illness Index, Thrombocytopenia, hemic and lymphatic diseases, Humans, Lupus Erythematosus, Systemic, Female, Research Article, Retrospective Studies
Abstract

The aim of the study was to examine the clinical characteristics and prognosis according to severity of thrombocytopenia and response to treatment for thrombocytopenia in patients with systemic lupus erythematosus (SLE). We retrospectively evaluated 230 SLE patients with thrombocytopenia, and reviewed their clinical data and laboratory findings. Thrombocytopenia was defined as platelet counts under 100,000/mm3, and patients were divided into 3 thrombocytopenia groups according to severity: mild (platelet counts >50,000/mm3), moderate (>20,000/mm3, ≤50,000/mm3), and severe (≤20,000/mm3). Clinical characteristics, treatments, and prognoses were compared among the groups. Furthermore, complete remission of thrombocytopenia was defined as platelet counts >100,000/mm3 after treatment. There was no significant difference in clinical or laboratory findings among the groups according to severity of thrombocytopenia. However, hemorrhagic complications were more frequent in severe thrombocytopenia (P

Published
2016

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