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92 results on '"Amaia Vilas-Zornoza"'

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1. Epigenetic-based differentiation therapy for Acute Myeloid Leukemia

2. Single-cell transcriptional profile of CD34+ hematopoietic progenitor cells from del(5q) myelodysplastic syndromes and impact of lenalidomide

3. Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures

4. The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes

5. Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia

6. In vivo CRISPR-Cas9 inhibition of hepatic LDH as treatment of primary hyperoxaluria

7. Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution

8. One-Step In Vitro Generation of ETV2-Null Pig Embryos

9. Immunological Biomarkers of Fatal COVID-19: A Study of 868 Patients

10. Immunologic characterization of COVID-19 patients with hematological cancer

11. Functional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD)

12. CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I

13. Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

14. Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

15. Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome.

16. Supplementary Table S3 from Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth

17. Supplementary Figures S1-S6 from Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth

18. BCMA CAR-T Cell Phenotype and Functionality Is Affected By Disease Stage of Multiple Myeloma Patients

19. Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML

20. Identification of Molecular Mechanisms Governing CAR-T Cell Response in MM Patients Using Single Cell Transcriptomics

21. Data from Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

22. Supplementary Figure 3 from Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

23. Supplementary Figure 1 from Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

24. Supplementary Information from Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

25. Supplementary Figure 2 from Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

26. Supplementary Figure 4 from Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

27. Supplementary Methods, Figures 1-3, Tables 1-6 from Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia

29. Novel epigenetic based differentiation therapy for Acute Myeloid Leukemia

30. Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution

31. Author response: Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution

32. CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome

33. Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with In Vivo Efficacy in Multiple Myeloma

34. Characterization of complete lncRNAs transcriptome reveals the functional and clinical impact of lncRNAs in multiple myeloma

35. A Multimodal Single Cell Atlas of Human Tonsils Reveals New Insights into T and B Cell Differentiation

36. An Atlas of Cells in the Human Tonsil

37. The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells

38. Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial Infarction

39. Revealing cell populations catching the early stages of the human embryo development in naïve pluripotent stem cells

40. Preneoplastic somatic mutations including

41. Preneoplastic somatic mutations including MYD88(L265P) in lymphoplasmacytic lymphoma

42. The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells

43. A diabetic milieu increases cellular susceptibility to SARS-CoV-2 infections in engineered human kidney organoids and diabetic patients

44. Gene Therapy Restores the Transcriptional Program of Hematopoietic Stem Cells in Fanconi Anemia

45. Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression

46. Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

47. Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with

48. Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development

49. Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma

50. Deep Deconvolution of the Hematopoietic Stem Cell Regulatory Microenvironment Reveals a High Degree of Specialization and Conservation Between Mouse and Human

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