Author: "Azam, Tariq U." / Publication Year Range: Last 10 years - Searchworks@Jio Institute Digital Library Search Results

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46 results on '"Azam, Tariq U."'

1. Intubation Decision Based on Illness Severity and Mortality in COVID-19: An International Study*

Author: Chalkias, Athanasios, Huang, Yiyuan, Ismail, Anis, Pantazopoulos, Ioannis, Papagiannakis, Nikolaos, Bitterman, Brayden, Anderson, Elizabeth, Catalan, Tonimarie, Erne, Grace K., Tilley, Caroline R., Alaka, Abiola, Amadi, Kingsley M., Presswalla, Feriel, Blakely, Pennelope, Bernal-Morell, Enrique, Cebreiros López, Iria, Eugen-Olsen, Jesper, García de Guadiana Romualdo, Luis, Giamarellos-Bourboulis, Evangelos J., Loosen, Sven H., Reiser, Jochen, Tacke, Frank, Skoulakis, Anargyros, Laou, Eleni, Banerjee, Mousumi, Pop-Busui, Rodica, Hayek, Salim S., Hayek, Salim S., Blakely, Pennelope, Launius, Christopher, Berlin, Hanna, Amadi, Kingsley M., Azam, Tariq U., Shadid, Husam, Pan, Michael, O’ Hayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Padalia, Kishan J., Anderson, Elizabeth, Perry, Danny, Bitar, Abbas, Kaakati, Rayan, Zhao, Lili, Zhao, Peiyao, Michaud, Erinleigh, Huang, Yiyuan, Catalan, Tonimarie, Khaleel, Ibrahim, Alaka, Abiola, Pop-Busui, Rodica, Banerjee, Mousumi, Tekumulla, Annika, Tilley, Caroline R., Tripathi, Medha, Vasbinder, Alexi, Bardwell, Alina, Presswalla, Feriel, Nelapudi, Namratha, Erne, Grace K., Chen, Jiazi, Mayette, Nathan, Sulaiman, Noor, Ismail, Anis, Pizzo, Ian, Bitterman, Brayden, Reiser, Jochen, Samelko, Beata, Hlepas, Alexander, Wang, Xuexiang, Patel, Priya, Chalkias, Athanasios, Pantazopoulos, Ioannis, Laou, Eleni, Skoulakis, Anargyros, Papagiannakis, Nikolaos, Eugen-Olsen, Jesper, Altintas, Izzet, Tingleff, Jens, Stauning, Marius, Houlind, Morten Baltzer, Lindstrøm, Mette B, Andersen, Ove, Gamst-Jensen, Hejdi, Hartmann Rasmussen, Line Jee, Rasmussen, Christian, Nehlin, Jan O., Kallemose, Thomas, Parvaiz, Imran, Loosen, Sven H., Luedde, Tom, Keitel, Verena, Giamarellos-Bourboulis, Evangelos J., Adami, Maria-Evangelia, Solomonidi, Nicky, Tsilika, Maria, Saridaki, Maria, Lekakis, Vasileios, Tacke, Frank, Tober-Lau, Pinkus, Mohr, Raphael, Kurth, Florian, Sander, Leif Erik, Jochum, Christoph, Garcia de Guadiana-Romualdo, Luis, Albaladejo-Otón, María Dolores, Rodríguez Mulero, María Dolores, Martínez, María Galindo, Olivo, Marta Hernández, Rodríguez, Valerio Campos, López, Iria Cebreiros, Carrillo, María Arnaldos, Noguera Velasco, Jose Antonio, Pascual Figal, Domingo A., Morell, Enrique Bernal, García, Antonia Alcaraz, Alcaraz García, María José, Martínez, Monica Martínez, Esteban-Torrella, Patricia, and Sancho-Rodríguez, Natalia
Published: 2024
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2. Biomarker Trends, Incidence, and Outcomes of Immune Checkpoint Inhibitor–Induced Myocarditis

Author: Vasbinder, Alexi, Chen, YeeAnn, Procureur, Adrien, Gradone, Allison, Azam, Tariq U., Perry, Daniel, Shadid, Husam, Anderson, Elizabeth, Catalan, Tonimarie, Blakely, Pennelope, Nelapudi, Namratha, Fardous, Mohamad, Bretagne, Marie C., Adie, Sarah K., Pogue, Kristen T., Leja, Monika, Yentz, Sarah, Schneider, Bryan, Fecher, Leslie A., Lao, Christopher D., Salem, Joe-Elie, and Hayek, Salim S.
Published: 2022
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3. Permissive Cardiotoxicity: The Clinical Crucible of Cardio-Oncology

Author: Porter, Charles, Azam, Tariq U., Mohananey, Divyanshu, Kumar, Rohit, Chu, Jian, Lenihan, Daniel, Dent, Susan, Ganatra, Sarju, Beasley, Gary S., and Okwuosa, Tochukwu
Published: 2022
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4. Kidney Recovery and Death in Critically Ill Patients With COVID-19–Associated Acute Kidney Injury Treated With Dialysis: The STOP-COVID Cohort Study

Author: Gupta, Hsu, Faugno, Goyal, Raichoudhury, Tariq, Meyer, Sharma, Leaf, Kshirsagar, Walther, Carl P., Anumudu, Samaya J., Arunthamakun, Justin, Kopecky, Kathleen F., Milligan, Gregory P., McCullough, Peter A., Nguyen, Thuy-Duyen, Shaefi, Shahzad, Krajewski, Megan L., Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D., Bauer, Kenneth A., Waikar, Sushrut S., Kibbelaar, Zoe A., Athavale, Ambarish M., Hart, Peter, Upadhyay, Shristi, Vohra, Ishaan, Oyintayo, Ajiboye, Green, Adam, Rachoin, Jean-Sebastien, Schorr, Christa A., Shea, Lisa, Edmonston, Daniel L., Mosher, Christopher L., Shehata, Alexandre M., Cohen, Zaza, Allusson, Valerie, Bambrick-Santoyo, Gabriela, Bhatti, Noor ul aain, Mehta, Bijal, WilliamsSamantha K. Brenner, Aquino, Walters, Patricia, Go, Ronaldo C., Rose, Keith M., Hernán, Miguel A., Zhou, Amy M., Kim, Ethan C., Lisk, Rebecca, Chan, Lili, Mathews, Kusum S., Coca, Steven G., Altman, Deena R., Saha, Aparna, Soh, Howard, Wen, Huei Hsun, Bose, Sonali, Leven, Emily A., Wang, Jing G., Mosoyan, Gohar, Pattharanitima, Pattharawin, Gallagher, Emily J., Friedman, Allon N., Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Kelly, Katherine J., Parikh, Chirag R., Garibaldi, Brian T., Corona-Villalobos, Celia P., Wen, Yumeng, Menez, Steven, Malik, Rubab F., Cervantes, Carmen Elena, Gautam, Samir C., Mallappallil, Mary C., Ouyang, Jie, John, Sabu, Yap, Ernie, Melaku, Yohannes, Mohamed, Ibrahim, Bajracharya, Siddhartha, Puri, Isha, Thaxton, Mariah, Bhattacharya, Jyotsna, Wagner, John, Boudourakis, Leon, Nguyen, H. Bryant, Ahoubim, Afshin, Thomas, Leslie F., Sirganagari, Dheeraj Reddy, Guru, Pramod K., Kashani, Kianoush, Tehranian, Shahrzad, Zhou, Yan, Bergl, Paul A., Rodriguez, Jesus, Shah, Jatan A., Gupta, Mrigank S., Kumar, Princy N., Lazarous, Deepa G., Kassaye, Seble G., Melamed, Michal L., Johns. Ryan Mocerino, Tanya S., Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V., Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Thakkar, Jyotsana, Kumar, Neelja, Ross, Michael J., Chang, Michael, Athreya, Akshay, Farag, Mohamed, Schenck, Edward J., Cho, Soo Jung, Plataki, Maria, Alvarez-Mulett, Sergio L., Gomez-Escobar, Luis G., Pan, Di, Lee, Stefi, Krishnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Srivastava, Anand, Leidner, Alexander S., Martinez, Carlos, Kruser, Jacqueline M., Wunderink, Richard G., Hodakowski, Alexander J., Velez, Juan Carlos Q., Price-Haywood, Eboni G., Matute-Trochez, Luis A., Hasty, Anna E., Mohamed, Muner M.B., Avasare, Rupali S., Zonies, David, Al-Samkari, Hanny, Leaf, Rebecca Karp, Rosovsky, Rachel, Sise, Meghan E., Newman, Erik T., Omar, Samah Abu, Pokharel, Kapil K., Sharma, Shreyak, Singh, Harkarandeep, Correa, Simon, Shaukat, Tanveer, Kamal, Omer, Wang, Wei, Lee, Meghan, Strohbehn, Ian A., Li, Jiahua, Mueller, Ariel L., Redfern, Roberta E., Cairl, Nicholas S., Naimy, Gabriel, Abu-Saif, Abeer, Hall, Danyell, Bickley, Laura, Rowan, Chris, Madhani-Lovely, Farah, Peev, Vasil, Reiser, Jochen, Byun, John J., Vissing, Andrew, Kapania, Esha M., Post, Zoe, Patel, Nilam P., Hermes, Joy-Marie, Sutherland, Anne K., Patrawalla, Amee, Finkel, Diana G., Danek, Barbara A., Arikapudi, Sowminya, Paer, Jeffrey M., Cangialosi, Peter, Liotta, Mark, Radbel, Jared, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T., Ahmed, Ayesha, Berim, Ilya, Vatson, Jayanth S., Karp, George, Anand, Shuchi, Levitt, Joseph E., Garcia, Pablo, Boyle, Suzanne M., Song, Rui, Zhang, Jingjing, Woo, Sang Hoon, Deng, Xiaoying, Katz-Greenberg, Goni, Sharshir, Moh’d A., Rusnak, Vadym V., Bansal, Anip, Podoll, Amber S., Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L., Rashidi, Arash, Hejal, Rana, Judd, Eric, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E., Adams, Jason Y., Chang, Steven Y., Beutler, Rebecca M., Schulze, Carl E., Macedo, Etienne, RheeKa, Harin, thleen D. Liu, Jotwani, Vasantha K., Koyner, Jay L., Shah, Chintan V., Jaikaransingh, Vishal, Toth-Manikowski, Stephanie M., Joo, Min J., Lash, James P., Neyra, Javier A., Chaaban, Nourhan, Elias, Madona, Ahmad, Yahya, Dy, Rajany, Iardino, Alfredo, Au, Elizabeth H., Sosa, Marie Anne, Taldone, Sabrina, Contreras, Gabriel, De La Zerda, David, Gershengorn, Hayley B., Fornoni, Alessia, Hayek, Salim S., Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U., Shadid, Husam, Pan, Michael, O’Hayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Padalia, Kishan J., Leya, Jeff, Donnelly, John P., Admon, Andrew J., Flythe, Jennifer E., Tugman, Matthew J., Chang, Emily H., Brown, Brent R., Leonberg-Yoo, Amanda K., Spiardi, Ryan C., Miano, Todd A., Roche, Meaghan S., Vasquez, Charles R., Bansal, Amar D., Ernecoff, Natalie C., Kapoor, Sanjana, Verma, Siddharth, Chen, Huiwen, Kovesdy, Csaba P., Molnar, Miklos Z., Azhar, Ambreen, Hedayati, S. Susan, Nadamuni, Mridula V., Shastri, Shani, Willett, Duwayne L., Short, Samuel A.P., Renaghan, Amanda D., Enfield, Kyle B., Bhatraju, Pavan K., Malik, A. Bilal, Semler, Matthew W., Vijayan, Anitha, Joy, Christina Mariyam, Li, Tingting, Goldberg, Seth, Kao, Patricia F., Schumaker, Greg L., Christov, Marta, Griffiths, Jennifer, Gupta, Sanjeev, Kapoor, Aromma, Chugh, Savneek, Wilson, Perry, Arora, Tanima, Ugwuowo, Ugochukwu, Hsu, Caroline M., Gupta, Shruti, Tighiouart, Hocine, Goyal, Nitender, Faugno, Anthony J., Tariq, Asma, Raichoudhury, Ritesh, Sharma, Jill H., Meyer, Leah, Kshirsagar, Ravi K., Jose, Aju, Leaf, David E., and Weiner, Daniel E.
Published: 2022
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5. Differences in Inflammation, Treatment, and Outcomes Between Black and Non-Black Patients Hospitalized for COVID-19: A Prospective Cohort Study

Author: Azam, Tariq U., Berlin, Hanna, Anderson, Elizabeth, Pan, Michael, Shadid, Husam R., Padalia, Kishan, O'Hayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Michaud, Erinleigh, Launius, Christopher, Blakely, Penelope, Bitar, Abbas, Willer, Cristen, Pop-Busui, Rodica, Carethers, John M., and Hayek, Salim S.
Published: 2022
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6. In-hospital cardiac arrest in critically ill patients with covid-19 : multicenter cohort study

Author: STOP-COVID Investigators, Hayek, Salim S, Brenner, Samantha K, Azam, Tariq U, Shadid, Husam R, Anderson, Elizabeth, Berlin, Hanna, Pan, Michael, Meloche, Chelsea, Feroz, Rafey, O’Hayer, Patrick, Kaakati, Rayan, Bitar, Abbas, Padalia, Kishan, Perry, Daniel, Blakely, Pennelope, Gupta, Shruti, Shaefi, Shahzad, Srivastava, Anand, Charytan, David M, Bansal, Anip, Mallappallil, Mary, Melamed, Michal L, Shehata, Alexandre M, Sunderram, Jag, Mathews, Kusum S, Sutherland, Anne K, Nallamothu, Brahmajee K, and Leaf, David E
Published: 2020

7. Modulation of the Association Between Age and Death by Risk Factor Burden in Critically Ill Patients With COVID-19

Author: Sunderraj, Ashwin, Cho, Chloe, Cai, Xuan, Gupta, Shruti, Mehta, Rupal, Isakova, Tamara, Leaf, David E., Srivastava, Anand, Walther, Carl P., Anumudu, Samaya J., Arunthamakun, Justin, Kopecky, Kathleen F., Milligan, Gregory P., McCullough, Peter A., Nguyen, Thuy-Duyen, Shaefi, Shahzad, Krajewski, Megan L., Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D., Waikar, Sushrut S., Kibbelaar, Zoe A., Athavale, Ambarish M., Hart, Peter, Upadhyay, Shristi, Vohra, Ishaan, Oyintayo, Ajiboye, Green, Adam, Rachoin, Jean-Sebastien, Schorr, Christa A., Shea, Lisa, Edmonston, Daniel L., Mosher, Christopher L., Shehata, Alexandre M., Cohen, Zaza, Allusson, Valerie, Bambrick-Santoyo, Gabriela, Bhatti, Noor ul aain, Mehta, Bijal, Williams, Aquino, Brenner, Samantha K., Walters, Patricia, Go, Ronaldo C., Rose, Keith M., Hernán, Miguel A., Zhou, Amy M., Kim, Ethan C., Lisk, Rebecca, Chan, Lili, Mathews, Kusum S., Coca, Steven G., Altman, Deena R., Saha, Aparna, Soh, Howard, Hsun Wen, Huei, Bose, Sonali, Leven, Emily A., Wang, Jing G., Mosoyan, Gohar, Nadkarni, Girish N., Pattharanitima, Pattharawin, Gallagher, Emily J., Friedman, Allon N., Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Kelly, Katherine J., Parikh, Chirag R., Garibaldi, Brian T., Corona-Villalobos, Celia P., Wen, Yumeng, Menez, Steven, Malik, Rubab F., Elena Cervantes, Carmen, Gautam, Samir C., Mallappallil, Mary C., Ouyang, Jie, John, Sabu, Yap, Ernie, Melaku, Yohannes, Mohamed, Ibrahim, Bajracharya, Siddhartha, Puri, Isha, Thaxton, Mariah, Bhattacharya, Jyotsna, Wagner, John, Boudourakis, Leon, Bryant Nguyen, H., Ahoubim, Afshin, Thomas, Leslie F., Sirganagari, Dheeraj Reddy, Guru, Pramod K., Kashani, Kianoush, Tehranian, Shahrzad, Zhou, Yan, Bergl, Paul A., Rodriguez, Jesus, Shah, Jatan A., Gupta, Mrigank S., Kumar, Princy N., Lazarous, Deepa G., Kassaye, Seble G., Melamed, Michal L., Johns, Tanya S., Mocerino, Ryan, Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V., Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Kumar, Neelja, Chang, Michael, Thakkar, Jyotsana, Raichoudhury, Ritesh, Athreya, Akshay, Farag, Mohamed, Schenck, Edward J., Cho, Soo Jung, Plataki, Maria, Alvarez-Mulett, Sergio L., Gomez-Escobar, Luis G., Pan, Di, Lee, Stefi, Krishnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Chaudhry, Sobaata, Wu, Benjamin, Modersitzki, Frank, Srivastava, Anand, Leidner, Alexander S., Martinez, Carlos, Kruser, Jacqueline M., Wunderink, Richard G., Hodakowski, Alexander J., Velez, Juan Carlos Q., Price-Haywood, Eboni G., Matute-Trochez, Luis A., Hasty, Anna E., Mohamed, Muner MB., Avasare, Rupali S., Zonies, David, Leaf, David E., Gupta, Shruti, Sise, Meghan E., Newman, Erik T., Abu Omar, Samah, Pokharel, Kapil K., Sharma, Shreyak, Singh, Harkarandeep, Correa, Simon, Shaukat, Tanveer, Kamal, Omer, Wang, Wei, Yang, Heather, Boateng, Jeffery O., Lee, Meghan, Strohbehn, Ian A., Li, Jiahua, Mueller, Ariel L., Redfern, Roberta E., Cairl, Nicholas S., Naimy, Gabriel, Abu-Saif, Abeer, Hall, Danyell, Bickley, Laura, Rowan, Chris, Madhani-Lovely, Farah, Cruz, Vivian S., Hess, Kristen M., Jacobs, Alanna L., Peev, Vasil, Reiser, Jochen, Byun, John J., Vissing, Andrew, Kapania, Esha M., Post, Zoe, Patel, Nilam P., Hermes, Joy-Marie, Sutherland, Anne K., Patrawalla, Amee, Finkel, Diana G., Danek, Barbara A., Arikapudi, Sowminya, Paer, Jeffrey M., Cangialosi, Peter, Liotta, Mark, Radbel, Jared, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T., Ahmed, Ayesha, Berim, Ilya, Vatson, Jayanth S., Anand, Shuchi, Levitt, Joseph E., Garcia, Pablo, Boyle, Suzanne M., Song, Rui, Zhang, Jingjing, Hoon Woo, Sang, Deng, Xiaoying, Katz-Greenberg, Goni, Senter, Katharine, Sharshir, Moh’d A., Rusnak, Vadym V., Ali, Muhammad Imran, Bansal, Anip, Podoll, Amber S., Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L., Douin, David J., Rashidi, Arash, Hejal, Rana, Judd, Eric, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E., Adams, Jason Y., Chang, Steven Y., Beutler, Rebecca M., Schulze, Carl E., Macedo, Etienne, Rhee, Harin, Liu, Kathleen D., Jotwani, Vasantha K., Koyner, Jay L., Shah, Chintan V., Jaikaransingh, Vishal, Toth-Manikowski, Stephanie M., Joo, Min J., Lash, James P., Neyra, Javier A., Chaaban, Nourhan, Elias, Madona, Ahmad, Yahya, Iardino, Alfredo, Au, Elizabeth H., Sharma, Jill H., Anne Sosa, Marie, Taldone, Sabrina, Contreras, Gabriel, De La Zerda, David, Gershengorn, Hayley B., Shukla, Bhavarth, Fornoni, Alessia, Ferreira, Tanira, Hayek, Salim S., Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U., Shadid, Husam, Pan, Michael, O’ Hayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Kaakati, Rayan, Perry, Danny, Bitar, Abbas, Anderson, Elizabeth, Padalia, Kishan J., Donnelly, John P., Admon, Andrew J., Flythe, Jennifer E., Tugman, Matthew J., Chang, Emily H., Brown, Brent R., Leonberg-Yoo, Amanda K., Spiardi, Ryan C., Miano, Todd A., Roche, Meaghan S., Vasquez, Charles R., Bansal, Amar D., Ernecoff, Natalie C., Kapoor, Sanjana, Verma, Siddharth, Chen, Huiwen, Kovesdy, Csaba P., Molnar, Miklos Z., Azhar, Ambreen, Susan Hedayati, S., Nadamuni, Mridula V., Shastri, Shani, Willett, Duwayne L., Short, Samuel A.P., Renaghan, Amanda D., Enfield, Kyle B., Bhatraju, Pavan K., Bilal Malik, A., Semler, Matthew W., Vijayan, Anitha, Mariyam Joy, Christina, Li, Tingting, Goldberg, Seth, Kao, Patricia F., Schumaker, Greg L., Goyal, Nitender, Faugno, Anthony J., Schumaker, Greg L., Hsu, Caroline M., Tariq, Asma, Meyer, Leah, Kshirsagar, Ravi K., Weiner, Daniel E., Jose, Aju, Christov, Marta, Griffiths, Jennifer, Gupta, Sanjeev, Kapoor, Aromma, Wilson, Perry, Arora, Tanima, and Ugwuowo, Ugochukwu
Published: 2022
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8. Biomarkers of chronic inflammation and cognitive decline: A prospective observational study

Author: Guduguntla, Bhavna A., primary, Vasbinder, Alexi, additional, Anderson, Elizabeth, additional, Azam, Tariq U., additional, Blakely, Pennelope, additional, Webster, Noah J., additional, Gonzalez, Richard, additional, Atonucci, Toni, additional, Heidebrink, Judith L., additional, Giordani, Bruno, additional, Zahodne, Laura, additional, Hampstead, Benjamin M., additional, Ajrouch, Kristine J., additional, and Hayek, Salim S., additional
Published: 2024
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9. Machine Learning Prediction of Death in Critically Ill Patients With Coronavirus Disease 2019

Author: Churpek, Matthew M., Gupta, Shruti, Spicer, Alexandra B., Hayek, Salim S., Srivastava, Anand, Chan, Lili, Melamed, Michal L., Brenner, Samantha K., Radbel, Jared, Madhani-Lovely, Farah, Bhatraju, Pavan K., Bansal, Anip, Green, Adam, Goyal, Nitender, Shaefi, Shahzad, Parikh, Chirag R., Semler, Matthew W., Leaf, David E., Walther, Carol P., Anumudu, Samaya J., Arunthamakun, Justin, Kopecky, Kathleen F., Milligan, Gregory P., McCullough, Peter A., Nguyen, ThuyDuyen, Shaefi, Shahzad, Krajewski, Megan L., Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D., Waikar, Sushrut S., Kibbelaar, Zoe A., Athavale, Ambarish M., Hart, Peter, Ajiboye, Oyintayo, Itteera, Matthew, Green, Adam, Rachoin, Jean-Sebastien, Schorr, Christa A., Shea, Lisa, Edmonston, Daniel L., Mosher, Christopher L., Shehata, Alexandre M., Cohen, Zaza, Allusson, Valerie, Bambrick-Santoyo, Gabriela, Bhatti, Noor ul aain, Metha, Bijal, Williams, Aquino, Brenner, Samantha K., Walters, Patricia, Go, Ronaldo C., Rose, Keith M., Hernán, Miguel A., Zhou, Amy M., Kim, Ethan C., Lisk, Rebecca, Chan, Lili, Mathews, Kusum S., Coca, Steven G., Altman, Deena R., Saha, Aparna, Soh, Howard, Wen, Huei Hsun, Bose, Sonali, Leven, Emily, Wang, Jing G., Mosoyan, Gohar, Nadkarni, Girish N., Friedman, Allon N., Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Parikh, Chirag R., Garibaldi, Brian T., Corona-Villalobos, Celia P., Wen, Yumeng, Menez, Steven, Malik, Rubab F., Cervantes, Carmen Elena, Gautam, Samir C., Chang, Crystal, Nguyen, H. Bryant, Ahoubim, Afshin, Thomas, Leslie F., Guru, Pramod K., Bergl, Paul A., Zhou, Yan, Rodriguez, Jesus, Shah, Jatan A., Gupta, Mrigank S., Kumar, Princy N., Lazarous, Deepa G., Kassaye, Seble G., Melamed, Michal L., Johns, Tanya S., Mocerino, Ryan, Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V., Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Thakkar, Jyotsana, Kumar, Neelja, Ross, Michael J., Chang, Michael, Raichoudhury, Ritesh, Schenck, Edward J., Cho, Soo Jung, Plataki, Maria, Alvarez-Mulett, Sergio L., Gomez-Escobar, Luis G., Pan, Di, Lee, Stefi, Krishnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Ross, Daniel W., Srivastava, Anand, Leidner, Alexander S., Martinez, Carlos, Kruser, Jacqueline M., Wunderink, Richard G., Hodakowski, Alexander J., Velez, Juan Carlos Q., Price-Haywood, Eboni G., Matute-Trochez, Luis A., Hasty, Anna E., Mohamed, Muner MB., Avasare, Rupali S., Zonies, David, Leaf, David E., Gupta, Shruti, Baron, Rebecca M., Sise, Meghan E., Newman, Erik T., Omar, Samah Abu, Pokharel, Kapil K., Sharma, Shreyak, Singh, Harkarandeep, Gaviria, Simon Correa, Shaukat, Tanveer, Kamal, Omer, Wang, Wei, Yang, Heather, Boateng, Jeffery O., Lee, Meghan, Strohbehn, Ian A., Li, Jiahua, Muhsin, Saif A., Mandel, Ernest I., Mueller, Ariel L., Cairl, Nicholas S., Madhani-Lovely, Farah, Rowan, Chris, Madhai-Lovely, Farah, Peev, Vasil, Reiser, Jochen, Byun, John J., Vissing, Andrew, Kapania, Esha M., Post, Zoe, Patel, Nilam P., Hermes, Joy-Marie, Sutherland, Anne K., Patrawalla, Amee, Finkel, Diana G., Danek, Barbara A., Arikapudi, Sowminya, Paer, Jeffrey M., Radbel, Jared, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T., Ahmed, Ayesha, Berim, Ilya, Vatson, Jayanth, Anand, Shuchi, Levitt, Joseph E., Garcia, Pablo, Boyle, Suzanne M., Song, Rui, Zhang, Jingjing, Sharshir, Moh’d A., Rusnak, Vadym V., Bansal, Anip, Podoll, Amber S., Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L., Rashidi, Arash, Hejal, Rana, Judd, Eric, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E., Adams, Jason Y., Chang, Steven Y., Beutler, Rebecca M., Schulze, Carl E., Macedo, Etienne, Rhee, Harin, Liu, Kathleen D., Jotwani, Vasantha K., Koyner, Jay L., Shah, Chintan V., Jaikaransingh, Vishal, Toth-Manikowski, Stephanie M., Joo, Min J., Lash, James P., Neyra, Javier A., Chaaban, Nourhan, Iardino, Alfredo, Au, Elizabeth H., Sharma, Jill H., Anne Sosa, Marie, Taldone, Sabrina, Contreras, Gabriel, De La Zerda, David, Gershengorn, Hayley B., Hayek, Salim S., Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U., Shadid, Husam, Pan, Michael, Hayer, Patrick O’, Meloche, Chelsea, Feroze, Rafey, Padalia, Kishan J., Leya, Jeff, Donnelly, John P., Admon, Andrew J., Flythe, Jennifer E., Tugman, Matthew J., Brown, Brent R., Leonberg-Yoo, Amanda K., Spiardi, Ryan C., Miano, Todd A., Roche, Meaghan S., Vasquez, Charles R., Bansal, Amar D., Ernecoff, Natalie C., Kovesdy, Csaba P., Molnar, Miklos Z., Hedayati, S. Susan, Nadamuni, Mridula V., Khan, Sadaf S., Willett, Duwayne L., Short, Samuel A.P., Renaghan, Amanda D., Bhatraju, Pavan, Malik, A. Bilal, Semler, Matthew W., Vijayan, Anitha, Mariyam Joy, Christina, Li, Tingting, Goldberg, Seth, Kao, Patricia F., Schumaker, Greg L., Goyal, Nitender, Faugno, Anthony J., Schumaker, Greg L., Hsu, Caroline M., Tariq, Asma, Meyer, Leah, Christov, Marta, Wilson, Francis P., Arora, Tanima, and Ugwuowo, Ugochukwu
Published: 2021
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10. Abstract 15938: B-type Natriuretic Peptide Levels Do Not Predict the Need for Mechanical Ventilation in Hospitalized Patients With COVID-19

Author: perry, Daniel, Azam, Tariq U, Shadid, Husam, Pan, Michael, Berlin, Hannah, Meloche, Chelsea, Feroze, Rafey, Leya, Jeff, OʼHayer, Patrick, Anderson, Elizabeth, Kaakati, Rayan, Abbas, Bitar, Padalia, Kishan, Blakley, Pennelope, Zhao, Peiyao, Zhao, Lili, and Hayek, Salim
Published: 2020
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11. Abstract 15365: Natural History of Immune Checkpoint Inhibitor Associated Myocarditis With Preserved Ejection Fraction

Author: Nowatzke, Joseph, Power, John R, Meijers, Wouter C, Orimoloye, Olusola, Fenioux, Charlotte, Tamura, Yuichi, Cautela, Jennifer, Lehmann, Lorenz H, Finke, Daniel, Hayek, Salim, Azam, Tariq U, Asnani, Aarti, Mehegan, Tyler, Weppler, Alison, Baik, Alan H, Aras, Mandar A, Narezkina, Anna, Arangalage, Dimitri, rocher, fanny, Alexandre, Gerard, Palaskas, Nicolas L, Salem, Joe-elie, and Moslehi, Javid
Published: 2020
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12. Abstract 14843: Electrocardiographic Manifestations of Immune Checkpoint Inhibitor Associated Myocarditis

Author: Power, John R, Alexandre, Joachim, Choudhary, Arrush, ozbay, benay, Palaskas, Nicolas L, Lehmann, Lorenz H, Finke, Daniel, Cautela, Jennifer, Thuny, Franck, Tamura, Yuichi, Hayek, Salim S, Azam, Tariq U, Asnani, Aarti, Mehegan, Tyler, Aras, Mandar A, Baik, Alan H, Gilstrap, Lauren, Laufer-Perl, Michal, Arangalage, Dimitri, Ewer, Steven, Martini, Matthew, Nowatzke, Joseph, Orimoloye, Olusola A, Brinkley, Douglas M, Meijers, Wouter C, Fenioux, Charlotte, EDERHY, Stephane, Moslehi, Javid J, and Salem, Joe-elie
Published: 2020
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13. SuPAR, biomarkers of inflammation, and severe outcomes in patients hospitalized for COVID‐19: The International Study of Inflammation in COVID‐19.

Author: Vasbinder, Alexi, Padalia, Kishan, Pizzo, Ian, Machado, Kristen, Catalan, Tonimarie, Presswalla, Feriel, Anderson, Elizabeth, Ismail, Anis, Hutten, Christina, Huang, Yiyuan, Blakely, Pennelope, Azam, Tariq U., Berlin, Hanna, Feroze, Rafey, Launius, Christopher, Meloche, Chelsea, Michaud, Erinleigh, O'Hayer, Patrick, Pan, Michael, and Shadid, Husam R.
Subjects: COVID-19, PLASMINOGEN activators, BIOMARKERS, TREATMENT effectiveness, C-reactive protein
Abstract: Severe coronavirus disease 2019 (COVID‐19) is a hyperinflammatory syndrome. The biomarkers of inflammation best suited to triage patients with COVID‐19 are unknown. We conducted a prospective multicenter observational study of adult patients hospitalized specifically for COVID‐19 from February 1, 2020 to October 19, 2022. Biomarkers measured included soluble urokinase plasminogen activator receptor (suPAR), C‐reactive protein, interleukin‐6, procalcitonin, ferritin, and D‐dimer. In‐hospital outcomes examined include death and the need for mechanical ventilation. Patients admitted in the United States (US, n = 1962) were used to compute area under the curves (AUCs) and identify biomarker cutoffs. The combined European cohorts (n = 1137) were used to validate the biomarker cutoffs. In the US cohort, 356 patients met the composite outcome of death (n = 197) or need for mechanical ventilation (n = 290). SuPAR was the most important predictor of the composite outcome and had the highest AUC (0.712) followed by CRP (0.642), ferritin (0.619), IL‐6 (0.614), D‐dimer (0.606), and lastly procalcitonin (0.596). Inclusion of other biomarkers did not improve discrimination. A suPAR cutoff of 4.0 ng/mL demonstrated a sensitivity of 95.4% (95% CI: 92.4%–98.0%) and negative predictive value (NPV) of 92.5% (95% CI: 87.5%–96.9%) for the composite outcome. Patients with suPAR < 4.0 ng/mL comprised 10.6% of the cohort and had a 0.8% probability of the composite outcome. Applying this cutoff to the validation cohort yielded a sensitivity of 93.8% (90.4%–96.7%) and NPV of 95.5% (93.1%–97.8%) for the composite outcome. Among commonly measured biomarkers, suPAR offered stronger discriminatory ability and may be useful in triaging low‐risk patients with COVID‐19. [ABSTRACT FROM AUTHOR]
Published: 2024
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14. Soluble Urokinase Plasminogen Activator Receptor and Venous Thromboembolism in COVID‐19

Author: Luo, Shengyuan, primary, Vasbinder, Alexi, additional, Du‐Fay‐de‐Lavallaz, Jeanne M., additional, Gomez, Joanne Michelle D., additional, Suboc, Tisha, additional, Anderson, Elizabeth, additional, Tekumulla, Annika, additional, Shadid, Husam, additional, Berlin, Hanna, additional, Pan, Michael, additional, Azam, Tariq U., additional, Khaleel, Ibrahim, additional, Padalia, Kishan, additional, Meloche, Chelsea, additional, O'Hayer, Patrick, additional, Catalan, Tonimarie, additional, Blakely, Pennelope, additional, Launius, Christopher, additional, Amadi, Kingsley‐Michael, additional, Pop‐Busui, Rodica, additional, Loosen, Sven H., additional, Chalkias, Athanasios, additional, Tacke, Frank, additional, Giamarellos‐Bourboulis, Evangelos J., additional, Altintas, Izzet, additional, Eugen‐Olsen, Jesper, additional, Williams, Kim A., additional, Volgman, Annabelle Santos, additional, Reiser, Jochen, additional, Hayek, Salim S., additional, Amadi, Kingsley, additional, O’Hayer, Patrick, additional, Feroze, Rafey, additional, Padalia, Kishan J., additional, Perry, Danny, additional, Bitar, Abbas, additional, Kaakati, Rayan, additional, Zhao, Lili, additional, Zhao, Peiyao, additional, Michaud, Erinleigh, additional, Huang, Yiyuan, additional, Catalan, Toniemarie, additional, Samelko, Beata, additional, Hlepas, Alexander, additional, Wang, Xuexiang, additional, Patel, Priya, additional, Tingleff, Jens, additional, Stauning, Marius, additional, Houlind, Morten Baltzer, additional, Lindstrøm, Mette B., additional, Andersen, Ove, additional, Gamst‐Jensen, Hejdi, additional, Rasmussen, Line Jee Hartmann, additional, Rasmussen, Christian, additional, Nehlin, Jan O., additional, Kallemose, Thomas, additional, Parvaiz, Imran, additional, Adami, Maria‐Evangelia, additional, Solomonidi, Nicky, additional, Tsilika, Maria, additional, Saridaki, Maria, additional, Lekakis, Vasileios, additional, Loosen, Sven, additional, Luedde, Tom, additional, Keitel, Verena, additional, Pantazopoulos, Ioannis, additional, Laou, Eleni, additional, Skoulakis, Anargyros, additional, Tober‐Lau, Pinkus, additional, Mohr, Raphael, additional, Kurth, Florian, additional, Sander, Leif Erik, additional, Jochum, Christoph, additional, and Koehler, Philipp, additional
Published: 2022
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15. Permissive Cardiotoxicity

Author: Porter, Charles, primary, Azam, Tariq U., additional, Mohananey, Divyanshu, additional, Kumar, Rohit, additional, Chu, Jian, additional, Lenihan, Daniel, additional, Dent, Susan, additional, Ganatra, Sarju, additional, Beasley, Gary S., additional, and Okwuosa, Tochukwu, additional
Published: 2022
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16. Inflammation, Hyperglycemia, and Adverse Outcomes in Individuals With Diabetes Mellitus Hospitalized for COVID-19

Author: Vasbinder, Alexi Anderson, Elizabeth Shadid, Husam Berlin, Hanna Pan, Michael Azam, Tariq U. Khaleel, Ibrahim Padalia, Kishan Meloche, Chelsea O'Hayer, Patrick Michaud, Erinleigh Catalan, Tonimarie Feroze, Rafey Blakely, Pennelope Launius, Christopher Huang, Yiyuan Zhao, Lili Ang, Lynn Mikhael, Monica Mizokami-Stout, Kara Pennathur, Subramaniam Kretzler, Matthias Loosen, Sven H. Chalkias, Athanasios Tacke, Frank Giamarellos-Bourboulis, Evangelos J. Reiser, Jochen Eugen-Olsen, Jesper Feldman, Eva L. Pop-Busui, Rodica Hayek, Salim S. Hayek, Salim S. Blakely, Pennelope Berlin, Hanna Azam, Tariq U. Shadid, Husam Pan, Michael O'Hayer, Patrick Meloche, Chelsea Feroze, Rafey Padalia, Kishan J. Anderson, Elizabeth Perry, Danny Bitar, Abbas Kaakati, Rayan Huang, Yiyuan Zhao, Lili Reiser, Jochen Samelko, Beata Hlepas, Alex Patel, Priya P. Wang, Xuexiang Eugen-Olsen, Jesper Altintas, Izzet Stauning, Marius Baltzer Houlind, Morten Lindstrøm, Mette B. Gamst-Jensen, Hejdi Hartmann, Line Jee Nehlin, Jan O. Kallemose, Thomas Parvaiz, Imran Rasmussen, Christian Andersen, Ove Tingleff, Jens Giamarellos-Bourboulis, Evangelos J. Adami, Maria-Evangelia Solomonidi, Nicky Tsilika, Maria Saridaki, Maria Lekakis, Vasileios Loosen, Sven H. Luedde, Tom Keitel, Verena Chalkias, Athanasios Arnaoutoglou, Eleni Pantazopoulos, Ioannis Laou, Eleni Kolonia, Konstantina Skoulakis, Anargyros Tacke, Frank Tober-Lau, Pinkus Mohr, Raphael Kurth, Florian Sander, Leif Erik Jochum, Christoph
Abstract: OBJECTIVE: Diabetes mellitus (DM) is a major risk factor for severe coronavirus disease 2019 (COVID-19) for reasons that are unclear. RESEARCH DESIGN AND METHODS: We leveraged the International Study of Inflammation in COVID-19 (ISIC), a multicenter observational study of 2,044 patients hospitalized with COVID-19, to characterize the impact of DM on in-hospital outcomes and assess the contribution of inflammation and hyperglycemia to the risk attributed to DM. We measured biomarkers of inflammation collected at hospital admission and collected glucose levels and insulin data throughout hospitalization. The primary outcome was the composite of in-hospital death, need for mechanical ventilation, and need for renal replacement therapy. RESULTS: Among participants (mean age 60 years, 58.2% males), those with DM (n = 686, 33.5%) had a significantly higher cumulative incidence of the primary outcome (37.8% vs. 28.6%) and higher levels of inflammatory biomarkers than those without DM. Among biomarkers, DM was only associated with higher soluble urokinase plasminogen activator receptor (suPAR) levels in multivariable analysis. Adjusting for suPAR levels abrogated the association between DM and the primary outcome (adjusted odds ratio 1.23 [95% CI 0.78, 1.37]). In mediation analysis, we estimated the proportion of the effect of DM on the primary outcome mediated by suPAR at 84.2%. Hyperglycemia and higher insulin doses were independent predictors of the primary outcome, with effect sizes unaffected by adjusting for suPAR levels. CONCLUSIONS: Our findings suggest that the association between DM and outcomes in COVID-19 is largely mediated by hyperinflammation as assessed by suPAR levels, while the impact of hyperglycemia is independent of inflammation.
Published: 2022

17. Association of early electrical changes with cardiovascular outcomes in immune checkpoint inhibitor myocarditis

Author: Power, John R., primary, Alexandre, Joachim, additional, Choudhary, Arrush, additional, Ozbay, Benay, additional, Hayek, Salim S., additional, Asnani, Aarti, additional, Tamura, Yuichi, additional, Aras, Mandar, additional, Cautela, Jennifer, additional, Thuny, Franck, additional, Gilstrap, Lauren, additional, Arangalage, Dimitri, additional, Ewer, Steven, additional, Huang, Shi, additional, Deswal, Anita, additional, Palaskas, Nicolas L., additional, Finke, Daniel, additional, Lehmann, Lorenz H., additional, Ederhy, Stephane, additional, Moslehi, Javid, additional, Salem, Joe-Elie, additional, Fenioux, Charlotte, additional, Abbar, Baptiste, additional, Allenbach, Yves, additional, Crusz, Shanthini M., additional, Ghosh, Arjun K., additional, Moran, Tyler, additional, Mehegan, Tyler, additional, Piro, Lawrence, additional, Chang, Wei-Ting, additional, Chahine, Johnny, additional, Flint, Danette, additional, Stringer, Ben, additional, Gounant, Valérie, additional, Nicol, Martin, additional, Baroudjian, Barouyr, additional, Zimmer, Marie-Claire, additional, Mervoyer, Elvire, additional, Leong, Darryl, additional, Morimoto, Ryota, additional, Piriou, Nicolas, additional, Monge, Cecilia, additional, Copeland, Amy, additional, Ghafourian, Kambiz, additional, Guha, Avirup, additional, Brodsky, Sergey, additional, Ben Zadok, Osnat Itzhaki, additional, Habib, Manhal, additional, Dy, Grace, additional, Warner, Ellen, additional, Laufer-Perl, Michal, additional, Koo Lin, Lily, additional, Narezkina, Ana, additional, Baik, Alan, additional, Lenneman, Carrie, additional, Vachhani, Pankit, additional, Azam, Tariq U., additional, Perry, Daniel, additional, Blakely, Pennelope, additional, Tajiri, Kazuko, additional, Martini, Matthew, additional, Nowatzke, Joseph, additional, Orimoloye, Olusola Ayodeji, additional, Hughes, Andrew, additional, Baldassarre, Lauren A., additional, and Patel, Milan, additional
Published: 2022
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18. Outcomes of critically ill solid organ transplant patients with COVID-19 in the United States

Author: Molnar, Miklos Z., Bhalla, Anshul, Azhar, Ambreen, Tsujita, Makoto, Talwar, Manish, Balaraman, Vasanthi, Sodhi, Amik, Kadaria, Dipen, Eason, James D., Hayek, Salim S., Coca, Steven G., Shaefi, Shahzad, Neyra, Javier A., Gupta, Shruti, Leaf, David E., Kovesdy, Csaba P., Walther, Carl P., Anumudu, Samaya J., Arunthamakun, Justin, Kopecky, Kathleen F., Milligan, Gregory P., McCullough, Peter A., Nguyen, Thuy‐Duyen, Krajewski, Megan L., Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D., Waikar, Sushrut S., Kibbelaar, Zoe A., Athavale, Ambarish M., Hart, Peter, Upadhyay, Shristi, Vohra, Ishaan, Oyintayo, Ajiboye, Green, Adam, Rachoin, Jean‐Sebastien, Schorr, Christa A., Shea, Lisa, Edmonston, Daniel L., Mosher, Christopher L., Shehata, Alexandre M, Cohen, Zaza, Allusson, Valerie, Bambrick‐Santoyo, Gabriela, Bhatti, Noor ul aain, Mehta, Bijal, Williams, Aquino, Brenner, Samantha K., Walters, Patricia, Go, Ronaldo C., Rose, Keith M., Hernán, Miguel A., Lisk, Rebecca, Zhou, Amy M., Kim, Ethan C., Chan, Lili, Mathews, Kusum S., Altman, Deena R., Saha, Aparna, Soh, Howard, Wen, Huei Hsun, Bose, Sonali, Leven, Emily A., Wang, Jing G., Mosoyan, Gohar, Nadkarni, Girish N., Pattharanitima, Pattharawin, Gallagher, Emily J., Friedman, Allon N., Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Kelly, Katherine J., Parikh, Chirag R., Garibaldi, Brian T., Corona‐Villalobos, Celia P., Wen, Yumeng, Menez, Steven, Malik, Rubab F., Cervantes, Carmen Elena, Gautam, Samir C., Mallappallil, Mary C., Ouyang, Jie, John, Sabu, Yap, Ernie, Melaku, Yohannes, Mohamed, Ibrahim, Bajracharya, Siddhartha, Puri, Isha, Thaxton, Mariah, Bhattacharya, Jyotsna, Wagner, John, Boudourakis, Leon, Nguyen, H. Bryant, Ahoubim, Afshin, Kashani, Kianoush, Tehranian, Shahrzad, Thomas, Leslie F., Sirganagari, Dheeraj Reddy, Guru, Pramod K., Zhou, Yan, Bergl, Paul A., Rodriguez, Jesus, Shah, Jatan A., Gupta, Mrigank S., Kumar, Princy N., Lazarous, Deepa G., Kassaye, Seble G., Melamed, Michal L., Johns, Tanya S., Mocerino, Ryan, Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V., Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Kumar, Neelja, Chang, Michael, Thakkar, Jyotsana, Raichoudhury, Ritesh, Athreya, Akshay, Farag, Mohamed, Schenck, Edward J., Cho, Soo Jung, Plataki, Maria, Alvarez‐Mulett, Sergio L., Gomez‐Escobar, Luis G., Pan, Di, Lee, Stefi, Krishnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Chaudhry, Sobaata, Wu, Benjamin, Modersitzki, Frank, Srivastava, Anand, Leidner, Alexander, Martinez, Carlos, Kruser, Jacqueline M., Wunderink, Richard G., Hodakowski, Alexander J., Velez, Juan Carlos Q., Price‐Haywood, Eboni G., Matute‐Trochez, Luis A., Hasty, Anna E., Mohamed, Muner MB, Avasare, Rupali S., Zonies, David, Leaf, David E, Sise, Meghan E., Newman, Erik T., Omar, Samah Abu, Pokharel, Kapil K., Sharma, Shreyak, Singh, Harkarandeep, Correa, Simon, Shaukat, Tanveer, Kamal, Omer, Wang, Wei, Yang, Heather, Boateng, Jeffery O., Lee, Meghan, Strohbehn, Ian A., Li, Jiahua, Mueller, Ariel L., Redfern, Roberta E., Cairl, Nicholas S., Naimy, Gabriel, Abu‐Saif, Abeer, Hall, Danyell, Bickley, Laura, Rowan, Chris, Madhani‐Lovely, Farah, Peev, Vasil, Reiser, Jochen, Byun, John J., Vissing, Andrew, Kapania, Esha M., Post, Zoe, Patel, Nilam P., Hermes, Joy‐Marie, Sutherland, Anne K., Patrawalla, Amee, Finkel, Diana G., Danek, Barbara A., Arikapudi, Sowminya, Paer, Jeffrey M., Cangialosi, Peter, Liotta, Mark, Radbel, Jared, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T., Ahmed, Ayesha, Berim, Ilya, Vatson, Jayanth S., Anand, Shuchi, Levitt, Joseph E., Garcia, Pablo, Boyle, Suzanne M., Song, Rui, Arif, Ali, Zhang, Jingjing, Woo, Sang Hoon, Deng, Xiaoying, Katz‐Greenberg, Goni, Senter, Katharine, Sharshir, Moh’d A., Rusnak, Vadym V, Ali, Muhammad Imran, Peters, Terri, Hughes, Kathy, Bansal, Anip, Podoll, Amber S., Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L., Douin, David J., Rashidi, Arash, Hejal, Rana, Judd, Eric, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E., Adams, Jason Y., Chang, Steven Y., Beutler, Rebecca M., Schulze, Carl E., Macedo, Etienne, Rhee, Harin, Liu, Kathleen D., Jotwani, Vasantha K., Koyner, Jay L., Shah, Chintan V., Jaikaransingh, Vishal, Toth‐Manikowski, Stephanie M., Joo, Min J., Lash, James P., Chaaban, Nourhan, Elias, Madona, Ahmad, Yahya, Iardino, Alfredo, Au, Elizabeth H., Sharma, Jill H., Sosa, Marie Anne, Taldone, Sabrina, Contreras, Gabriel, Zerda, David De La, Fornoni, Alessia, Gershengorn, Hayley B., Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U., Shadid, Husam, Pan, Michael, Hayer, Patrick O’, Meloche, Chelsea, Feroze, Rafey, Kishan J. Padalia, Bitar, Abbas, Leya, Jeff, Donnelly, John P., Admon, Andrew J., Flythe, Jennifer E., Tugman, Matthew J., Chang, Emily H., Brown, Brent R., Leonberg‐Yoo, Amanda K., Spiardi, Ryan C., Miano, Todd A., Roche, Meaghan S., Vasquez, Charles R., Bansal, Amar D., Ernecoff, Natalie C., Kapoor, Sanjana, Verma, Siddharth, Chen, Huiwen, Hedayati, S. Susan, Nadamuni, Mridula V., Shastri, Shani, Willett, Duwayne L., Short, Samuel A.P., Renaghan, Amanda D., Enfield, Kyle B., Bhatraju, Pavan K., Malik, A. Bilal, Semler, Matthew W., Vijayan, Anitha, Joy, Christina Mariyam, Li, Tingting, Goldberg, Seth, Kao, Patricia F., Schumaker, Greg L., Goyal, Nitender, Faugno, Anthony J., Hsu, Caroline M., Tariq, Asma, Meyer, Leah, Kshirsagar, Ravi K., Jose, Aju, Weiner, Daniel E., Christov, Marta, Griffiths, Jennifer, Gupta, Sanjeev, Kapoor, Aromma, Wilson, Perry, Arora, Tanima, and Ugwuowo, Ugochukwu
Subjects: Male, medicine.medical_specialty, Critical Illness, medicine.medical_treatment, Comorbidity, 030230 surgery, Organ transplantation, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Intensive care, medicine, Humans, Immunology and Allergy, Pharmacology (medical), Hospital Mortality, Renal replacement therapy, Pandemics, Survival rate, Aged, Transplantation, SARS-CoV-2, business.industry, Acute kidney injury, COVID-19, Original Articles, Organ Transplantation, Middle Aged, medicine.disease, United States, Hospitalization, Survival Rate, Intensive Care Units, Relative risk, Propensity score matching, Original Article, Female, business, Follow-Up Studies, Cohort study
Abstract: National data on patient characteristics, treatment, and outcomes of critically ill coronavirus disease 2019 (COVID-19) solid organ transplant (SOT) patients are limited. We analyzed data from a multicenter cohort study of adults with laboratory-confirmed COVID-19 admitted to intensive care units (ICUs) at 68 hospitals across the United States from March 4 to May 8, 2020. From 4153 patients, we created a propensity score matched cohort of 386 patients, including 98 SOT patients and 288 non-SOT patients. We used a binomial generalized linear model (log-binomial model) to examine the association of SOT status with death and other clinical outcomes. Among the 386 patients, the median age was 60 years, 72% were male, and 41% were black. Death within 28 days of ICU admission was similar in SOT and non-SOT patients (40% and 43%, respectively; relative risk [RR] 0.92; 95% confidence interval [CI]: 0.70-1.22). Other outcomes and requirement for organ support including receipt of mechanical ventilation, development of acute respiratory distress syndrome, and receipt of vasopressors were also similar between groups. There was a trend toward higher risk of acute kidney injury requiring renal replacement therapy in SOT vs. non-SOT patients (37% vs. 27%; RR [95% CI]: 1.34 [0.97-1.85]). Death and organ support requirement were similar between SOT and non-SOT critically ill patients with COVID-19.
Published: 2020

19. Right Ventricular Dysfunction in Critically Ill Patients With COVID-19

Author: Brenner, Samantha K., primary, Azam, Tariq U., additional, Parrillo, Joseph E., additional, Hollenberg, Steven M., additional, Anderson, Elizabeth, additional, O'Hayer, Patrick, additional, Berlin, Hanna, additional, Blakley, Pennelope, additional, Bitar, Abbas, additional, and Hayek, Salim S., additional
Published: 2022
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20. Inflammation, Hyperglycemia, and Adverse Outcomes in Individuals With Diabetes Mellitus Hospitalized for COVID-19

Author: Vasbinder, Alexi, primary, Anderson, Elizabeth, primary, Shadid, Husam, primary, Berlin, Hanna, primary, Pan, Michael, primary, Azam, Tariq U., primary, Khaleel, Ibrahim, primary, Padalia, Kishan, primary, Meloche, Chelsea, primary, O’Hayer, Patrick, primary, Michaud, Erinleigh, primary, Catalan, Tonimarie, primary, Feroze, Rafey, primary, Blakely, Pennelope, primary, Launius, Christopher, primary, Huang, Yiyuan, primary, Zhao, Lili, primary, Ang, Lynn, primary, Mikhael, Monica, primary, Mizokami-Stout, Kara, primary, Pennathur, Subramaniam, primary, Kretzler, Matthias, primary, Loosen, Sven H., primary, Chalkias, Athanasios, primary, Tacke, Frank, primary, Giamarellos-Bourboulis, Evangelos J., primary, Reiser, Jochen, primary, Eugen-Olsen, Jesper, primary, Feldman, Eva L., primary, Pop-Busui, Rodica, primary, Hayek, Salim S., primary, and group, the ISIC, primary
Published: 2022
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21. Association of Surge Conditions with Mortality Among Critically Ill Patients with COVID-19

Author: Keene, Adam B., primary, Admon, Andrew J., additional, Brenner, Samantha K., additional, Gupta, Shruti, additional, Lazarous, Deepa, additional, Leaf, David E., additional, Gershengorn, Hayley B., additional, Walther, Carl P., additional, Anumudu, Samaya J., additional, Arunthamakun, Justin, additional, Kopecky, Kathleen F., additional, Milligan, Gregory P., additional, McCullough, Peter A., additional, Nguyen, Thuy-Duyen, additional, Shaefi, Shahzad, additional, O’Gara, Brian P., additional, Krajewski, Megan L., additional, Baskin, Sean M., additional, Shankar, Sidharth, additional, Valencia, Juan D., additional, Pannu, Ameeka, additional, Hayes, Margaret M., additional, Grandin, E. Wilson, additional, Waikar, Sushrut S., additional, Kibbelaar, Zoe A., additional, Athavale, Ambarish M., additional, Hart, Peter, additional, Upadhyay, Shristi, additional, Vohra, Ishaan, additional, Oyintayo, Ajiboye, additional, Green, Adam, additional, Rachoin, Jean-Sebastien, additional, Schorr, Christa A., additional, Shea, Lisa, additional, Edmonston, Daniel L., additional, Mosher, Christopher L., additional, Shehata, Alexandre M., additional, Cohen, Zaza, additional, Allusson, Valerie, additional, Bambrick-Santoyo, Gabriela, additional, ul aain Bhatti, Noor, additional, Mehta, Bijal, additional, Williams, Aquino, additional, Walters, Patricia, additional, Go, Ronaldo C., additional, Rose, Keith M., additional, Hernán;, Miguel A., additional, Lisk, Rebecca, additional, Chan, Lili, additional, Mathews, Kusum S., additional, Coca, Steven G., additional, Altman, Deena R., additional, Saha, Aparna, additional, Soh, Howard, additional, Wen, Huei Hsun, additional, Bose, Sonali, additional, Leven, Emily A., additional, Wang, Jing G., additional, Mosoyan, Gohar, additional, Nadkarni, Girish N., additional, Pattharanitima, Pattharawin, additional, Gallagher, Emily J., additional, Friedman, Allon N., additional, Guirguis, John, additional, Kapoor, Rajat, additional, Meshberger, Christopher, additional, Kelly, Katherine J., additional, Parikh, Chirag R., additional, Garibaldi, Brian T., additional, Corona-Villalobos, Celia P., additional, Wen, Yumeng, additional, Menez, Steven, additional, Malik, Rubab F., additional, Elena Cervantes, Carmen, additional, Gautam, Samir C., additional, Mallappallil, Mary C., additional, Ouyang, Jie, additional, John, Sabu, additional, Yap, Ernie, additional, Melaku, Yohannes, additional, Mohamed, Ibrahim, additional, Bajracharya, Siddhartha, additional, Puri, Isha, additional, Thaxton, Mariah, additional, Bhattacharya, Jyotsna, additional, Wagner, John, additional, Boudourakis, Leon, additional, Nguyen, H. Bryant, additional, Ahoubim, Afshin, additional, Thomas, Leslie F., additional, Sirganagari, Dheeraj Reddy, additional, Guru, Pramod K., additional, Kashani, Kianoush, additional, Tehranian, Shahrzad, additional, Zhou, Yan, additional, Bergl, Paul A., additional, Rodriguez, Jesus, additional, Shah, Jatan A., additional, Gupta, Mrigank S., additional, Kumar, Princy N., additional, Lazarous, Deepa G., additional, Kassaye, Seble G., additional, Melamed, Michal L., additional, Johns, Tanya S., additional, Mocerino, Ryan, additional, Prudhvi, Kalyan, additional, Zhu, Denzel, additional, Levy, Rebecca V., additional, Azzi, Yorg, additional, Fisher, Molly, additional, Yunes, Milagros, additional, Sedaliu, Kaltrina, additional, Golestaneh, Ladan, additional, Brogan, Maureen, additional, Kumar, Neelja, additional, Chang, Michael, additional, Thakkar, Jyotsana, additional, Raichoudhury, Ritesh, additional, Athreya, Akshay, additional, Farag, Mohamed, additional, Schenck, Edward J., additional, Jung Cho, Soo, additional, Plataki, Maria, additional, Alvarez-Mulett, Sergio L., additional, Gomez-Escobar, Luis G., additional, Pan, Di, additional, Lee, Stefi, additional, Krishnan, Jamuna, additional, Whalen, William, additional, Charytan, David, additional, Macina, Ashley, additional, Chaudhry, Sobaata, additional, Wu, Benjamin, additional, Modersitzki, Frank, additional, Srivastava, Anand, additional, Leidner, Alexander S., additional, Martinez, Carlos, additional, Kruser, Jacqueline M., additional, Wunderink, Richard G., additional, Hodakowski, Alexander J., additional, Velez, Juan Carlos Q., additional, Price-Haywood, Eboni G., additional, Matute-Trochez, Luis A., additional, Hasty, Anna E., additional, Mohamed, Muner MB., additional, Avasare, Rupali S., additional, Zonies, David, additional, Sise, Meghan E., additional, Newman, Erik T., additional, Abu Omar, Samah, additional, Pokharel, Kapil K., additional, Sharma, Shreyak, additional, Singh, Harkarandeep, additional, Correa, Simon, additional, Shaukat, Tanveer, additional, Kamal, Omer, additional, Wang, Wei, additional, Yang, Heather, additional, Boateng, Jeffery O., additional, Lee, Meghan, additional, Strohbehn, Ian A., additional, Li, Jiahua, additional, Mueller, Ariel L., additional, Redfern, Roberta E., additional, Cairl, Nicholas S., additional, Naimy, Gabriel, additional, Abu-Saif, Abeer, additional, Hall, Danyell, additional, Bickley, Laura, additional, Rowan, Chris, additional, Madhani-Lovely, Farah, additional, Peev, Vasil, additional, Reiser, Jochen, additional, Byun, John J., additional, Vissing, Andrew, additional, Kapania, Esha M., additional, Post, Zoe, additional, Patel, Nilam P., additional, Hermes, Joy-Marie, additional, Sutherland, Anne K., additional, Patrawalla, Amee, additional, Finkel, Diana G., additional, Danek, Barbara A., additional, Arikapudi, Sowminya, additional, Paer, Jeffrey M., additional, Cangialosi, Peter, additional, Liotta, Mark, additional, Radbel, Jared, additional, Puri, Sonika, additional, Sunderram, Jag, additional, Scharf, Matthew T., additional, Ahmed, Ayesha, additional, Berim, Ilya, additional, Vatson, Jayanth S., additional, Anand, Shuchi, additional, Levitt, Joseph E., additional, Garcia, Pablo, additional, Boyle, Suzanne M., additional, Song, Rui, additional, Arif, Ali, additional, Zhang, Jingjing, additional, Woo, Sang Hoon, additional, Deng, Xiaoying, additional, Katz-Greenberg, Goni, additional, Senter, Katharine, additional, Sharshir, Moh’d A., additional, Rusnak, Vadym V., additional, Imran Ali, Muhammad, additional, Peters, Terri, additional, Hughes, Kathy, additional, Bansal, Anip, additional, Podoll, Amber S., additional, Chonchol, Michel, additional, Sharma, Sunita, additional, Burnham, Ellen L., additional, Rashidi, Arash, additional, Hejal, Rana, additional, Judd, Eric, additional, Latta, Laura, additional, Tolwani, Ashita, additional, Albertson, Timothy E., additional, Adams, Jason Y., additional, Chang, Steven Y., additional, Beutler, Rebecca M., additional, Schulze, Carl E., additional, Macedo, Etienne, additional, Rhee, Harin, additional, Liu, Kathleen D., additional, Jotwani, Vasantha K., additional, Koyner, Jay L., additional, Kunczt, Alissa, additional, Shah, Chintan V., additional, Jaikaransingh, Vishal, additional, Toth-Manikowski, Stephanie M., additional, Joo, Min J., additional, Lash, James P., additional, Neyra, Javier A., additional, Chaaban, Nourhan, additional, Elias, Madona, additional, Ahmad, Yahya, additional, Dy, Rajany, additional, Iardino, Alfredo, additional, Au, Elizabeth H., additional, Sharma, Jill H., additional, Anne Sosa, Marie, additional, Taldone, Sabrina, additional, Contreras, Gabriel, additional, De La Zerda, David, additional, Fornoni, Alessia, additional, Hayek, Salim S., additional, Blakely, Pennelope, additional, Berlin, Hanna, additional, Azam, Tariq U., additional, Shadid, Husam, additional, Pan, Michael, additional, O” Hayer, Patrick, additional, Meloche, Chelsea, additional, Feroze, Rafey, additional, Padalia, Kishan J., additional, Bitar, Abbas, additional, Leya, Jeff, additional, Donnelly, John P., additional, Flythe, Jennifer E., additional, Tugman, Matthew J., additional, Chang, Emily H., additional, Brown, Brent R., additional, Leonberg-Yoo, Amanda K., additional, Spiardi, Ryan C., additional, Miano, Todd A., additional, Roche, Meaghan S., additional, Vasquez, Charles R., additional, Bansal, Amar D., additional, Ernecoff, Natalie C., additional, Kapoor, Sanjana, additional, Verma, Siddharth, additional, Chen, Huiwen, additional, Kovesdy, Csaba P., additional, Molnar, Miklos Z., additional, Azhar, Ambreen, additional, Susan Hedayati, S., additional, Nadamuni, Mridula V., additional, Shastri, Shani, additional, Willett, Duwayne L., additional, Short, Samuel A.P., additional, Renaghan, Amanda D., additional, Enfield, Kyle B., additional, Bhatraju, Pavan K., additional, Bilal Malik, A., additional, Semler, Matthew W., additional, Vijayan, Anitha, additional, Mariyam Joy, Christina, additional, Li, Tingting, additional, Goldberg, Seth, additional, Kao, Patricia F., additional, Schumaker, Greg L., additional, Goyal, Nitender, additional, Faugno, Anthony J., additional, Hsu, Caroline M., additional, Tariq, Asma, additional, Meyer, Leah, additional, Kshirsagar, Ravi K., additional, Jose, Aju, additional, Weiner, Daniel E., additional, Christov, Marta, additional, Chugh, Savneek, additional, Griffiths, Jennifer, additional, Gupta, Sanjeev, additional, Kapoor, Aromma, additional, Wilson, Perry, additional, Arora, Tanima, additional, and Ugwuowo, Ugochukwu, additional
Published: 2021
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22. Electrocardiographic Manifestations of Immune Checkpoint Inhibitor Myocarditis

Author: Power, John R., primary, Alexandre, Joachim, additional, Choudhary, Arrush, additional, Ozbay, Benay, additional, Hayek, Salim, additional, Asnani, Aarti, additional, Tamura, Yuichi, additional, Aras, Mandar, additional, Cautela, Jennifer, additional, Thuny, Franck, additional, Gilstrap, Lauren, additional, Arangalage, Dimitri, additional, Ewer, Steven, additional, Huang, Shi, additional, Deswal, Anita, additional, Palaskas, Nicolas L., additional, Finke, Daniel, additional, Lehmann, Lorenz, additional, Ederhy, Stephane, additional, Moslehi, Javid, additional, Salem, Joe-Elie, additional, Abbar, Baptiste, additional, Allenbach, Yves, additional, Azam, Tariq U., additional, Baik, Alan, additional, Baldassarre, Lauren A., additional, Baroudjian, Barouyr, additional, Blakley, Pennelope, additional, Brodsky, Sergey, additional, Chahine, Johnny, additional, Chan, Wei-Ting, additional, Copeland, Amy, additional, Crusz, Shanthini M., additional, Dy, Grace, additional, Fenioux, Charlotte, additional, Ghafourian, Kambiz, additional, Ghosh, Arjun K., additional, Gounant, Valérie, additional, Guha, Avirup, additional, Habib, Manhal, additional, Zadok, Osnat Itzhaki Ben, additional, Lin, Lily Koo, additional, Laufer-Perl, Michal, additional, Lenneman, Carrie, additional, Leong, Darryl, additional, Martini, Matthew, additional, Meheghan, Tyler, additional, Mervoyer, Elvire, additional, Monge, Cecilia, additional, Morimoto, Ryota, additional, Narezkina, Anna, additional, Nicol, Martin, additional, Nowatzke, Joseph, additional, Orimoloye, Olusola Ayodeji, additional, Patel, Milan, additional, Perry, Daniel, additional, Piriou, Nicolas, additional, Piro, Lawrence, additional, Moran, Tyler, additional, Stringer, Ben, additional, Tajiri, Kazuko, additional, Vachhani, Pankit, additional, Warner, Ellen, additional, and Zimmer, Marie-Claire, additional
Published: 2021
Full Text: View/download PDF

23. Performance of crisis standards of care guidelines in a cohort of critically ill COVID-19 patients in the United States

Author: Walther, Carl P., Anumudu, Samaya J., Arunthamakun, Justin, Kopecky, Kathleen F., Milligan, Gregory P., McCullough, Peter A., Nguyen, Thuy-Duyen, Shaefi, Shahzad, Krajewski, Megan L., Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D., Waikar, Sushrut S., Kibbelaar, Zoe A., Athavale, Ambarish M., Hart, Peter, Upadhyay, Shristi, Vohra, Ishaan, Oyintayo, Ajiboye, Green, Adam, Rachoin, Jean-Sebastien, Schorr, Christa A., Shea, Lisa, Edmonston, Daniel L., Mosher, Christopher L., Shehata, Alexandre M., Cohen, Zaza, Allusson, Valerie, Bambrick-Santoyo, Gabriela, ul aain Bhatti, Noor, Mehta, Bijal, Williams, Aquino, Brenner, Samantha K., Walters, Patricia, Go, Ronaldo C., Rose, Keith M., Hernán, Miguel A., Zhou, Amy M., Kim, Ethan C., Lisk, Rebecca, Chan, Lili, Mathews, Kusum S., Coca, Steven G., Altman, Deena R., Saha, Aparna, Soh, Howard, Wen, Huei Hsun, Bose, Sonali, Leven, Emily A., Wang, Jing G., Mosoyan, Gohar, Nadkarni, Girish N., Pattharanitima, Pattharawin, Friedman, Allon N., Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Kelly, Katherine J., Parikh, Chirag R., Garibaldi, Brian T., Corona-Villalobos, Celia P., Wen, Yumeng, Menez, Steven, Malik, Rubab F., Cervantes, Elena, Gautam, Samir, Mallappallil, Mary C., Ouyang, Jie, John, Sabu, Yap, Ernie, Melaku, Yohannes, Mohamed, Ibrahim, Bajracharya, Siddartha, Puri, Isha, Thaxton, Mariah, Bhattacharya, Jyotsna, Wagner, John, Boudourakis, Leon, Nguyen, H. Bryant, Ahoubim, Afshin, Thomas, Leslie F., Sirganagari, Dheeraj Reddy, Guru, Pramod K., Kashani, Kianoush, Zhou, Yan, Bergl, Paul A., Rodriguez, Jesus, Shah, Jatan A., Gupta, Mrigank S., Kumar, Princy N., Lazarous, Deepa G., Kassaye, Seble G., Melamed, Michal L., Johns, Tanya S., Mocerino, Ryan, Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V., Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Kumar, Neelja, Chang, Michael, Raichoudhury, Ritesh, Athreya, Akshay, Farag, Mohamed, Schenck, Edward J., Cho, Soo Jung, Plataki, Maria, Alvarez-Mulett, Sergio L., Gomez-Escobar, Luis G., Pan, Di, Lee, Stefi, Krishnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Chaudhry, Sobaata, Wu, Benjamin, Modersitzki, Frank, Srivastava, Anand, Leidner, Alexander S., Martinez, Carlos, Kruser, Jacqueline M., Wunderink, Richard G., Hodakowski, Alexander J., Velez, Juan Carlos Q., Price-Haywood, Eboni G., Matute-Trochez, Luis A., Hasty, Anna E., Mohamed, Muner MB., Avasare, Rupali S., Zonies, David, Leaf, David E., Gupta, Shruti, Sise, Meghan E., Newman, Erik T., Abu Omar, Samah, Pokharel, Kapil K., Sharma, Shreyak, Singh, Harkarandeep, Correa, Simon, Shaukat, Tanveer, Kamal, Omer, Wang, Wei, Yang, Heather, Boateng, Jeffery O., Lee, Meghan, Strohbehn, Ian A., Li, Jiahua, Mueller, Ariel L., Redfern, Roberta, Cairl, Nicholas S., Naimy, Gabriel, Abu-Saif, Abeer, Hall, Danyell, Bickley, Laura, Rowan, Chris, Madhani-Lovely, Farah, Cruz, Vivian S., Hess, Kristen M., Jacobs, Alanna L., Peev, Vasil, Reiser, Jochen, Byun, John J., Vissing, Andrew, Kapania, Esha M., Post, Zoe, Patel, Nilam P., Hermes, Joy-Marie, Sutherland, Anne K., Patrawalla, Amee, Finkel, Diana G., Danek, Barbara A., Arikapudi, Sowminya, Paer, Jeffrey M., Cangialosi, Peter, Liotta, Mark, Radbel, Jared, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T., Ahmed, Ayesha, Berim, Ilya, Vatson, Jayanth S., Anand, Shuchi, Levitt, Joseph E., Boyle, Suzanne M., Song, Rui, Zhang, Jingjing, Woo, Sang Hoon, Deng, Xiaoying, Katz-Greenberg, Goni, Senter, Katharine, Sharshir, Moh’d A., Rusnak, Vadym V., Ali, Muhammad Imran, Bansal, Anip, Podoll, Amber S., Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L., Rashidi, Arash, Hejal, Rana, Judd, Eric, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E., Adams, Jason Y., Chang, Steven Y., Beutler, Rebecca M., Macedo, Etienne, Rhee, Harin, Liu, Kathleen D., Jotwani, Vasantha K., Koyner, Jay L., Shah, Chintan V., Jaikaransingh, Vishal, Toth-Manikowski, Stephanie M., Joo, Min J., Lash, James P., Neyra, Javier A., Chaaban, Nourhan, Elias, Madona, Ahmad, Yahya, Iardino, Alfredo, Au, Elizabeth H., Sharma, Jill H., Sosa, Marie Anne, Taldone, Sabrina, Contreras, Gabriel, De La Zerda, David, Gershengorn, Hayley B., Shukla, Bhavarth, Fornoni, Alessia, Ferreira, Tanira, Hayek, Salim S., Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U., Shadid, Husam, Pan, Michael, O’ Hayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Kaakati, Rayan, Perry, Danny, Bitar, Abbas, Anderson, Elizabeth, Padalia, Kishan J., Donnelly, John P., Admon, Andrew J., Flythe, Jennifer E., Tugman, Matthew J., Chang, Emily H., Brown, Brent R., Leonberg-Yoo, Amanda K., Spiardi, Ryan C., Miano, Todd A., Roche, Meaghan S., Vasquez, Charles R., Bansal, Amar D., Ernecoff, Natalie C., Kapoor, Sanjana, Verma, Siddharth, Kovesdy, Csaba P., Molnar, Miklos Z., Azhar, Ambreen, Hedayati, S. Susan, Nadamuni, Mridula V., Shastri, Shani, Willett, Duwayne L., Short, Samuel A.P., Renaghan, Amanda D., Enfield, Kyle B., Bhatraju, Pavan K., Malik, A. Bilal, Semler, Matthew W., Vijayan, Anitha, Joy, Christina Mariyam, Li, Tingting, Goldberg, Seth, Kao, Patricia F., Schumaker, Greg L., Goyal, Nitender, Faugno, Anthony J., Hsu, Caroline M., Tariq, Asma, Meyer, Leah, Kshirsagar, Ravi K., Weiner, Daniel E., Jose, Aju, Christov, Marta, Griffiths, Jennifer, Gupta, Sanjeev, Kapoor, Aromma, Wilson, Perry, Arora, Tanima, Ugwuowo, Ugochukwu, Jezmir, Julia L., Bharadwaj, Maheetha, Chaitoff, Alexander, Diephuis, Bradford, Crowley, Conor P., Kishore, Sandeep P., Goralnick, Eric, Merriam, Louis T., Milliken, Aimee, Rhee, Chanu, Sadovnikoff, Nicholas, Shah, Sejal B., Feldman, William B., and Kim, Edy Y.
Published: 2021
Full Text: View/download PDF

24. Performance of crisis standards of care guidelines in a cohort of critically ill COVID-19 patients in the United States

Author: Jezmir, Julia L., primary, Bharadwaj, Maheetha, additional, Chaitoff, Alexander, additional, Diephuis, Bradford, additional, Crowley, Conor P., additional, Kishore, Sandeep P., additional, Goralnick, Eric, additional, Merriam, Louis T., additional, Milliken, Aimee, additional, Rhee, Chanu, additional, Sadovnikoff, Nicholas, additional, Shah, Sejal B., additional, Gupta, Shruti, additional, Leaf, David E., additional, Feldman, William B., additional, Kim, Edy Y., additional, Walther, Carl P., additional, Anumudu, Samaya J., additional, Arunthamakun, Justin, additional, Kopecky, Kathleen F., additional, Milligan, Gregory P., additional, McCullough, Peter A., additional, Nguyen, Thuy-Duyen, additional, Shaefi, Shahzad, additional, Krajewski, Megan L., additional, Shankar, Sidharth, additional, Pannu, Ameeka, additional, Valencia, Juan D., additional, Waikar, Sushrut S., additional, Kibbelaar, Zoe A., additional, Athavale, Ambarish M., additional, Hart, Peter, additional, Upadhyay, Shristi, additional, Vohra, Ishaan, additional, Oyintayo, Ajiboye, additional, Green, Adam, additional, Rachoin, Jean-Sebastien, additional, Schorr, Christa A., additional, Shea, Lisa, additional, Edmonston, Daniel L., additional, Mosher, Christopher L., additional, Shehata, Alexandre M., additional, Cohen, Zaza, additional, Allusson, Valerie, additional, Bambrick-Santoyo, Gabriela, additional, ul aain Bhatti, Noor, additional, Mehta, Bijal, additional, Williams, Aquino, additional, Brenner, Samantha K., additional, Walters, Patricia, additional, Go, Ronaldo C., additional, Rose, Keith M., additional, Hernán, Miguel A., additional, Zhou, Amy M., additional, Kim, Ethan C., additional, Lisk, Rebecca, additional, Chan, Lili, additional, Mathews, Kusum S., additional, Coca, Steven G., additional, Altman, Deena R., additional, Saha, Aparna, additional, Soh, Howard, additional, Wen, Huei Hsun, additional, Bose, Sonali, additional, Leven, Emily A., additional, Wang, Jing G., additional, Mosoyan, Gohar, additional, Nadkarni, Girish N., additional, Pattharanitima, Pattharawin, additional, Friedman, Allon N., additional, Guirguis, John, additional, Kapoor, Rajat, additional, Meshberger, Christopher, additional, Kelly, Katherine J., additional, Parikh, Chirag R., additional, Garibaldi, Brian T., additional, Corona-Villalobos, Celia P., additional, Wen, Yumeng, additional, Menez, Steven, additional, Malik, Rubab F., additional, Cervantes, Elena, additional, Gautam, Samir, additional, Mallappallil, Mary C., additional, Ouyang, Jie, additional, John, Sabu, additional, Yap, Ernie, additional, Melaku, Yohannes, additional, Mohamed, Ibrahim, additional, Bajracharya, Siddartha, additional, Puri, Isha, additional, Thaxton, Mariah, additional, Bhattacharya, Jyotsna, additional, Wagner, John, additional, Boudourakis, Leon, additional, Nguyen, H. Bryant, additional, Ahoubim, Afshin, additional, Thomas, Leslie F., additional, Sirganagari, Dheeraj Reddy, additional, Guru, Pramod K., additional, Kashani, Kianoush, additional, Zhou, Yan, additional, Bergl, Paul A., additional, Rodriguez, Jesus, additional, Shah, Jatan A., additional, Gupta, Mrigank S., additional, Kumar, Princy N., additional, Lazarous, Deepa G., additional, Kassaye, Seble G., additional, Melamed, Michal L., additional, Johns, Tanya S., additional, Mocerino, Ryan, additional, Prudhvi, Kalyan, additional, Zhu, Denzel, additional, Levy, Rebecca V., additional, Azzi, Yorg, additional, Fisher, Molly, additional, Yunes, Milagros, additional, Sedaliu, Kaltrina, additional, Golestaneh, Ladan, additional, Brogan, Maureen, additional, Kumar, Neelja, additional, Chang, Michael, additional, Raichoudhury, Ritesh, additional, Athreya, Akshay, additional, Farag, Mohamed, additional, Schenck, Edward J., additional, Cho, Soo Jung, additional, Plataki, Maria, additional, Alvarez-Mulett, Sergio L., additional, Gomez-Escobar, Luis G., additional, Pan, Di, additional, Lee, Stefi, additional, Krishnan, Jamuna, additional, Whalen, William, additional, Charytan, David, additional, Macina, Ashley, additional, Chaudhry, Sobaata, additional, Wu, Benjamin, additional, Modersitzki, Frank, additional, Srivastava, Anand, additional, Leidner, Alexander S., additional, Martinez, Carlos, additional, Kruser, Jacqueline M., additional, Wunderink, Richard G., additional, Hodakowski, Alexander J., additional, Velez, Juan Carlos Q., additional, Price-Haywood, Eboni G., additional, Matute-Trochez, Luis A., additional, Hasty, Anna E., additional, Mohamed, Muner MB., additional, Avasare, Rupali S., additional, Zonies, David, additional, Sise, Meghan E., additional, Newman, Erik T., additional, Abu Omar, Samah, additional, Pokharel, Kapil K., additional, Sharma, Shreyak, additional, Singh, Harkarandeep, additional, Correa, Simon, additional, Shaukat, Tanveer, additional, Kamal, Omer, additional, Wang, Wei, additional, Yang, Heather, additional, Boateng, Jeffery O., additional, Lee, Meghan, additional, Strohbehn, Ian A., additional, Li, Jiahua, additional, Mueller, Ariel L., additional, Redfern, Roberta, additional, Cairl, Nicholas S., additional, Naimy, Gabriel, additional, Abu-Saif, Abeer, additional, Hall, Danyell, additional, Bickley, Laura, additional, Rowan, Chris, additional, Madhani-Lovely, Farah, additional, Cruz, Vivian S., additional, Hess, Kristen M., additional, Jacobs, Alanna L., additional, Peev, Vasil, additional, Reiser, Jochen, additional, Byun, John J., additional, Vissing, Andrew, additional, Kapania, Esha M., additional, Post, Zoe, additional, Patel, Nilam P., additional, Hermes, Joy-Marie, additional, Sutherland, Anne K., additional, Patrawalla, Amee, additional, Finkel, Diana G., additional, Danek, Barbara A., additional, Arikapudi, Sowminya, additional, Paer, Jeffrey M., additional, Cangialosi, Peter, additional, Liotta, Mark, additional, Radbel, Jared, additional, Puri, Sonika, additional, Sunderram, Jag, additional, Scharf, Matthew T., additional, Ahmed, Ayesha, additional, Berim, Ilya, additional, Vatson, Jayanth S., additional, Anand, Shuchi, additional, Levitt, Joseph E., additional, Boyle, Suzanne M., additional, Song, Rui, additional, Zhang, Jingjing, additional, Woo, Sang Hoon, additional, Deng, Xiaoying, additional, Katz-Greenberg, Goni, additional, Senter, Katharine, additional, Sharshir, Moh’d A., additional, Rusnak, Vadym V., additional, Ali, Muhammad Imran, additional, Bansal, Anip, additional, Podoll, Amber S., additional, Chonchol, Michel, additional, Sharma, Sunita, additional, Burnham, Ellen L., additional, Rashidi, Arash, additional, Hejal, Rana, additional, Judd, Eric, additional, Latta, Laura, additional, Tolwani, Ashita, additional, Albertson, Timothy E., additional, Adams, Jason Y., additional, Chang, Steven Y., additional, Beutler, Rebecca M., additional, Macedo, Etienne, additional, Rhee, Harin, additional, Liu, Kathleen D., additional, Jotwani, Vasantha K., additional, Koyner, Jay L., additional, Shah, Chintan V., additional, Jaikaransingh, Vishal, additional, Toth-Manikowski, Stephanie M., additional, Joo, Min J., additional, Lash, James P., additional, Neyra, Javier A., additional, Chaaban, Nourhan, additional, Elias, Madona, additional, Ahmad, Yahya, additional, Iardino, Alfredo, additional, Au, Elizabeth H., additional, Sharma, Jill H., additional, Sosa, Marie Anne, additional, Taldone, Sabrina, additional, Contreras, Gabriel, additional, De La Zerda, David, additional, Gershengorn, Hayley B., additional, Shukla, Bhavarth, additional, Fornoni, Alessia, additional, Ferreira, Tanira, additional, Hayek, Salim S., additional, Blakely, Pennelope, additional, Berlin, Hanna, additional, Azam, Tariq U., additional, Shadid, Husam, additional, Pan, Michael, additional, O’ Hayer, Patrick, additional, Meloche, Chelsea, additional, Feroze, Rafey, additional, Kaakati, Rayan, additional, Perry, Danny, additional, Bitar, Abbas, additional, Anderson, Elizabeth, additional, Padalia, Kishan J., additional, Donnelly, John P., additional, Admon, Andrew J., additional, Flythe, Jennifer E., additional, Tugman, Matthew J., additional, Chang, Emily H., additional, Brown, Brent R., additional, Leonberg-Yoo, Amanda K., additional, Spiardi, Ryan C., additional, Miano, Todd A., additional, Roche, Meaghan S., additional, Vasquez, Charles R., additional, Bansal, Amar D., additional, Ernecoff, Natalie C., additional, Kapoor, Sanjana, additional, Verma, Siddharth, additional, Kovesdy, Csaba P., additional, Molnar, Miklos Z., additional, Azhar, Ambreen, additional, Hedayati, S. Susan, additional, Nadamuni, Mridula V., additional, Shastri, Shani, additional, Willett, Duwayne L., additional, Short, Samuel A.P., additional, Renaghan, Amanda D., additional, Enfield, Kyle B., additional, Bhatraju, Pavan K., additional, Malik, A. Bilal, additional, Semler, Matthew W., additional, Vijayan, Anitha, additional, Joy, Christina Mariyam, additional, Li, Tingting, additional, Goldberg, Seth, additional, Kao, Patricia F., additional, Schumaker, Greg L., additional, Goyal, Nitender, additional, Faugno, Anthony J., additional, Hsu, Caroline M., additional, Tariq, Asma, additional, Meyer, Leah, additional, Kshirsagar, Ravi K., additional, Weiner, Daniel E., additional, Jose, Aju, additional, Christov, Marta, additional, Griffiths, Jennifer, additional, Gupta, Sanjeev, additional, Kapoor, Aromma, additional, Wilson, Perry, additional, Arora, Tanima, additional, and Ugwuowo, Ugochukwu, additional
Published: 2021
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25. Identification of Distinct Clinical Subphenotypes in Critically Ill Patients With COVID-19

Author: Vasquez, Charles R., primary, Gupta, Shruti, additional, Miano, Todd A., additional, Roche, Meaghan, additional, Hsu, Jesse, additional, Yang, Wei, additional, Holena, Daniel N., additional, Reilly, John P., additional, Schrauben, Sarah J., additional, Leaf, David E., additional, Shashaty, Michael G.S., additional, Walther, Carl P., additional, Anumudu, Samaya J., additional, Arunthamakun, Justin, additional, Kopecky, Kathleen F., additional, Milligan, Gregory P., additional, McCullough, Peter A., additional, Nguyen, Thuy-Duyen, additional, Shaefi, Shahzad, additional, Krajewski, Megan L., additional, Shankar, Sidharth, additional, Pannu, Ameeka, additional, Valencia, Juan D., additional, Waikar, Sushrut S., additional, Kibbelaar, Zoe A., additional, Athavale, Ambarish M., additional, Hart, Peter, additional, Upadhyay, Shristi, additional, Vohra, Ishaan, additional, Oyintayo, Ajiboye, additional, Green, Adam, additional, Rachoin, Jean-Sebastien, additional, Schorr, Christa A., additional, Shea, Lisa, additional, Edmonston, Daniel L., additional, Mosher, Christopher L., additional, Shehata, Alexandre M., additional, Cohen, Zaza, additional, Allusson, Valerie, additional, Bambrick-Santoyo, Gabriela, additional, Bhatti, Noor ul aain, additional, Mehta, Bijal, additional, Williams, Aquino, additional, Brenner, Samantha K., additional, Walters, Patricia, additional, Go, Ronaldo C., additional, Rose, Keith M., additional, Chan, Lili, additional, Mathews, Kusum S., additional, Coca, Steven G., additional, Altman, Deena R., additional, Saha, Aparna, additional, Soh, Howard, additional, Wen, Huei Hsun, additional, Bose, Sonali, additional, Leven, Emily A., additional, Wang, Jing G., additional, Mosoyan, Gohar, additional, Nadkarni, Girish N., additional, Pattharanitima, Pattharawin, additional, Gallagher, Emily J., additional, Friedman, Allon N., additional, Guirguis, John, additional, Kapoor, Rajat, additional, Meshberger, Christopher, additional, Kelly, Katherine J., additional, Parikh, Chirag R., additional, Garibaldi, Brian T., additional, Corona-Villalobos, Celia P., additional, Wen, Yumeng, additional, Menez, Steven, additional, Malik, Rubab F., additional, Cervantes, Carmen Elena, additional, Gautam, Samir C., additional, Mallappallil, Mary C., additional, Ouyang, Jie, additional, John, Sabu, additional, Yap, Ernie, additional, Melaku, Yohannes, additional, Mohamed, Ibrahim, additional, Bajracharya, Siddhartha, additional, Puri, Isha, additional, Thaxton, Mariah, additional, Bhattacharya, Jyotsna, additional, Wagner, John, additional, Boudourakis, Leon, additional, Nguyen, H. Bryant, additional, Ahoubim, Afshin, additional, Kashani, Kianoush, additional, Tehranian, Shahrzad, additional, Thomas, Leslie F., additional, Sirganagari, Dheeraj Reddy, additional, Guru, Pramod K., additional, Zhou, Yan, additional, Bergl, Paul A., additional, Rodriguez, Jesus, additional, Shah, Jatan A., additional, Gupta, Mrigank S., additional, Kumar, Princy N., additional, Lazarous, Deepa G., additional, Kassaye, Seble G., additional, Melamed, Michal L., additional, Johns, Tanya S., additional, Mocerino, Ryan, additional, Prudhvi, Kalyan, additional, Zhu, Denzel, additional, Levy, Rebecca V., additional, Azzi, Yorg, additional, Fisher, Molly, additional, Yunes, Milagros, additional, Sedaliu, Kaltrina, additional, Golestaneh, Ladan, additional, Brogan, Maureen, additional, Kumar, Neelja, additional, Chang, Michael, additional, Thakkar, Jyotsana, additional, Raichoudhury, Ritesh, additional, Athreya, Akshay, additional, Farag, Mohamed, additional, Schenck, Edward J., additional, Cho, Soo Jung, additional, Plataki, Maria, additional, Alvarez-Mulett, Sergio L., additional, Gomez-Escobar, Luis G., additional, Pan, Di, additional, Lee, Stefi, additional, Krishnan, Jamuna, additional, Whalen, William, additional, Charytan, David, additional, Macina, Ashley, additional, Chaudhry, Sobaata, additional, Wu, Benjamin, additional, Modersitzki, Frank, additional, Srivastava, Anand, additional, Leidner, Alexander S., additional, Martinez, Carlos, additional, Kruser, Jacqueline M., additional, Wunderink, Richard G., additional, Hodakowski, Alexander J., additional, Velez, Juan Carlos Q., additional, Price-Haywood, Eboni G., additional, Matute-Trochez, Luis A., additional, Hasty, Anna E., additional, Mohamed, Muner M.B., additional, Avasare, Rupali S., additional, Zonies, David, additional, Sise, Meghan E., additional, Newman, Erik T., additional, Omar, Samah Abu, additional, Pokharel, Kapil K., additional, Sharma, Shreyak, additional, Singh, Harkarandeep, additional, Correa, Simon, additional, Shaukat, Tanveer, additional, Kamal, Omer, additional, Wang, Wei, additional, Yang, Heather, additional, Boateng, Jeffery O., additional, Lee, Meghan, additional, Strohbehn, Ian A., additional, Li, Jiahua, additional, Mueller, Ariel L., additional, Redfern, Roberta E., additional, Cairl, Nicholas S., additional, Naimy, Gabriel, additional, Abu-Saif, Abeer, additional, Hall, Danyell, additional, Bickley, Laura, additional, Rowan, Chris, additional, Madhani-Lovely, Farah, additional, Peev, Vasil, additional, Reiser, Jochen, additional, Byun, John J., additional, Vissing, Andrew, additional, Kapania, Esha M., additional, Post, Zoe, additional, Patel, Nilam P., additional, Hermes, Joy-Marie, additional, Sutherland, Anne K., additional, Patrawalla, Amee, additional, Finkel, Diana G., additional, Danek, Barbara A., additional, Arikapudi, Sowminya, additional, Paer, Jeffrey M., additional, Cangialosi, Peter, additional, Liotta, Mark, additional, Radbel, Jared, additional, Puri, Sonika, additional, Sunderram, Jag, additional, Scharf, Matthew T., additional, Ahmed, Ayesha, additional, Berim, Ilya, additional, Vatson, Jayanth S., additional, Anand, Shuchi, additional, Levitt, Joseph E., additional, Garcia, Pablo, additional, Boyle, Suzanne M., additional, Song, Rui, additional, Zhang, Jingjing, additional, Woo, Sang Hoon, additional, Deng, Xiaoying, additional, Katz-Greenberg, Goni, additional, Senter, Katharine, additional, Sharshir, Moh’d A., additional, Rusnak, Vadym V., additional, Ali, Muhammad Imran, additional, Bansal, Anip, additional, Podoll, Amber S., additional, Chonchol, Michel, additional, Sharma, Sunita, additional, Burnham, Ellen L., additional, Rashidi, Arash, additional, Hejal, Rana, additional, Judd, Eric, additional, Latta, Laura, additional, Tolwani, Ashita, additional, Albertson, Timothy E., additional, Adams, Jason Y., additional, Chang, Steven Y., additional, Beutler, Rebecca M., additional, Schulze, Carl E., additional, Macedo, Etienne, additional, Rhee, Harin, additional, Liu, Kathleen D., additional, Jotwani, Vasantha K., additional, Koyner, Jay L., additional, Kunczt, Alissa, additional, Shah, Chintan V., additional, Jaikaransingh, Vishal, additional, Toth-Manikowski, Stephanie M., additional, Joo, Min J., additional, Lash, James P., additional, Neyra, Javier A., additional, Chaaban, Nourhan, additional, Ahmad, Yahya, additional, Elias, Madona, additional, Dy, Rajany, additional, Iardino, Alfredo, additional, Au, Elizabeth H., additional, Sharma, Jill H., additional, Sosa, Marie Anne, additional, Taldone, Sabrina, additional, Contreras, Gabriel, additional, De La Zerda, David, additional, Gershengorn, Hayley B., additional, Hayek, Salim S., additional, Blakely, Pennelope, additional, Berlin, Hanna, additional, Azam, Tariq U., additional, Shadid, Husam, additional, Pan, Michael, additional, Hayer, Patrick O’, additional, Meloche, Chelsea, additional, Feroze, Rafey, additional, Kaakati, Rayan, additional, Perry, Danny, additional, Bitar, Abbas, additional, Anderson, Elizabeth, additional, Padalia, Kishan J., additional, Donnelly, John P., additional, Admon, Andrew J., additional, Flythe, Jennifer E., additional, Tugman, Matthew J., additional, Chang, Emily H., additional, Brown, Brent R., additional, Leonberg-Yoo, Amanda K., additional, Spiardi, Ryan C., additional, Roche, Meaghan S., additional, Vasquez, Charles R., additional, Bansal, Amar D., additional, Ernecoff, Natalie C., additional, Kapoor, Sanjana, additional, Verma, Siddharth, additional, Chen, Huiwen, additional, Kovesdy, Csaba P., additional, Molnar, Miklos Z., additional, Azhar, Ambreen, additional, Hedayati, S. Susan, additional, Nadamuni, Mridula V., additional, Shastri, Shani, additional, Willett, Duwayne L., additional, Short, Samuel A.P., additional, Renaghan, Amanda D., additional, Enfield, Kyle B., additional, Bhatraju, Pavan K., additional, Malik, A. Bilal, additional, Semler, Matthew W., additional, Vijayan, Anitha, additional, Joy, Christina Mariyam, additional, Li, Tingting, additional, Goldberg, Seth, additional, Kao, Patricia F., additional, Schumaker, Greg L., additional, Goyal, Nitender, additional, Faugno, Anthony J., additional, Hsu, Caroline M., additional, Tariq, Asma, additional, Meyer, Leah, additional, Kshirsagar, Ravi K., additional, Weiner, Daniel E., additional, Jose, Aju, additional, Christov, Marta, additional, Griffiths, Jennifer, additional, Gupta, Sanjeev, additional, Kapoor, Aromma, additional, Chugh, Savneek, additional, Wilson, Perry, additional, Arora, Tanima, additional, and Ugwuowo, Ugochukwu, additional
Published: 2021
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26. Hospital-Level Variation in Death for Critically Ill Patients with COVID-19

Author: Churpek, Matthew M., primary, Gupta, Shruti, additional, Spicer, Alexandra B., additional, Parker, William F., additional, Fahrenbach, John, additional, Brenner, Samantha K., additional, Leaf, David E., additional, Walther, Carl P., additional, Anumudu, Samaya J., additional, Arunthamakun, Justin, additional, Kopecky, Kathleen F., additional, Milligan, Gregory P., additional, McCullough, Peter A., additional, Nguyen, Thuy-Duyen, additional, Shaefi, Shahzad, additional, Krajewski, Megan L., additional, Shankar, Sidharth, additional, Pannu, Ameeka, additional, Valencia, Juan D., additional, Waikar, Sushrut S., additional, Kibbelaar, Zoe A., additional, Athavale, Ambarish M., additional, Hart, Peter, additional, Upadhyay, Shristi, additional, Vohra, Ishaan, additional, Green, Adam, additional, Rachoin, Jean-Sebastien, additional, Schorr, Christa A., additional, Shea, Lisa, additional, Edmonston, Daniel L., additional, Mosher, Christopher L., additional, Shehata, Alexandre M., additional, Cohen, Zaza, additional, Allusson, Valerie, additional, Bambrick-Santoyo, Gabriela, additional, ul aain Bhatti, Noor, additional, Mehta, Bijal, additional, Williams, Aquino, additional, Walters, Patricia, additional, Go, Ronaldo C., additional, Rose, Keith M., additional, Hernán, Miguel A., additional, Chan, Lili, additional, Mathews, Kusum S., additional, Coca, Steven G., additional, Altman, Deena R., additional, Saha, Aparna, additional, Soh, Howard, additional, Wen, Huei Hsun, additional, Bose, Sonali, additional, Leven, Emily A., additional, Wang, Jing G., additional, Mosoyan, Gohar, additional, Nadkarni, Girish N., additional, Pattharanitima, Pattharawin, additional, Gallagher, Emily J., additional, Friedman, Allon N., additional, Guirguis, John, additional, Kapoor, Rajat, additional, Meshberger, Christopher, additional, Kelly, Katherine J., additional, Parikh, Chirag R., additional, Garibaldi, Brian T., additional, Corona-Villalobos, Celia P., additional, Wen, Yumeng, additional, Menez, Steven, additional, Malik, Rubab F., additional, Cervantes, Elena, additional, Gautam, Samir, additional, Mallappallil, Mary C., additional, Ouyang, Jie, additional, John, Sabu, additional, Yap, Ernie, additional, Melaku, Yohannes, additional, Mohamed, Ibrahim, additional, Bajracharya, Siddartha, additional, Puri, Isha, additional, Thaxton, Mariah, additional, Bhattacharya, Jyotsna, additional, Wagner, John, additional, Boudourakis, Leon, additional, Nguyen, H. Bryant, additional, Ahoubim, Afshin, additional, Thomas, Leslie F., additional, Sirganagari, Dheeraj Reddy, additional, Guru, Pramod K., additional, Kashani, Kianoush, additional, Tehranian, Shahrzad, additional, Zhou, Yan, additional, Bergl, Paul A., additional, Rodriguez, Jesus, additional, Shah, Jatan A., additional, Gupta, Mrigank S., additional, Kumar, Princy N., additional, Lazarous, Deepa G., additional, Kassaye, Seble G., additional, Melamed, Michal L., additional, Johns, Tanya S., additional, Mocerino, Ryan, additional, Prudhvi, Kalyan, additional, Zhu, Denzel, additional, Levy, Rebecca V., additional, Azzi, Yorg, additional, Fisher, Molly, additional, Yunes, Milagros, additional, Sedaliu, Kaltrina, additional, Golestaneh, Ladan, additional, Brogan, Maureen, additional, Kumar, Neelja, additional, Chang, Michael, additional, Thakkar, Jyotsana, additional, Raichoudhury, Ritesh, additional, Athreya, Akshay, additional, Farag, Mohamed, additional, Schenck, Edward J., additional, Cho, Soo Jung, additional, Plataki, Maria, additional, Alvarez-Mulett, Sergio L., additional, Gomez-Escobar, Luis G., additional, Pan, Di, additional, Lee, Stefi, additional, Krishnan, Jamuna, additional, Whalen, William, additional, Charytan, David, additional, Macina, Ashley, additional, Chaudhry, Sobaata, additional, Wu, Benjamin, additional, Modersitzki, Frank, additional, Srivastava, Anand, additional, Leidner, Alexander S., additional, Martinez, Carlos, additional, Kruser, Jacqueline M., additional, Wunderink, Richard G., additional, Hodakowski, Alexander J., additional, Velez, Juan Carlos Q., additional, Price-Haywood, Eboni G., additional, Matute-Trochez, Luis A., additional, Hasty, Anna E., additional, Mohamed, Muner M. B., additional, Avasare, Rupali S., additional, Zonies, David, additional, Sise, Meghan E., additional, Newman, Erik T., additional, Abu Omar, Samah, additional, Pokharel, Kapil K., additional, Sharma, Shreyak, additional, Singh, Harkarandeep, additional, Correa, Simon, additional, Shaukat, Tanveer, additional, Kamal, Omer, additional, Wang, Wei, additional, Yang, Heather, additional, Boateng, Jeffery O., additional, Lee, Meghan, additional, Strohbehn, Ian A., additional, Li, Jiahua, additional, Mueller, Ariel L., additional, Redfern, Roberta, additional, Cairl, Nicholas S., additional, Naimy, Gabriel, additional, Abu-Saif, Abeer, additional, Hall, Danyell, additional, Bickley, Laura, additional, Rowan, Chris, additional, Madhai-Lovely, Farah, additional, Peev, Vasil, additional, Reiser, Jochen, additional, Byun, John J., additional, Vissing, Andrew, additional, Kapania, Esha M., additional, Post, Zoe, additional, Patel, Nilam P., additional, Hermes, Joy-Marie, additional, Sutherland, Anne K., additional, Patrawalla, Amee, additional, Finkel, Diana G., additional, Danek, Barbara A., additional, Arikapudi, Sowminya, additional, Paer, Jeffrey M., additional, Cangialosi, Peter, additional, Liotta, Mark, additional, Radbel, Jared, additional, Sunderram, Jag, additional, Puri, Sonika, additional, Vatson, Jayanth S., additional, Scharf, Matthew T., additional, Ahmed, Ayesha, additional, Berim, Ilya, additional, Anand, Shuchi, additional, Levitt, Joseph E., additional, Garcia, Pablo, additional, Boyle, Suzanne M., additional, Song, Rui, additional, Arif, Ali, additional, Zhang, Jingjing, additional, Woo, Sang Hoon, additional, Deng, Xiaoying, additional, Katz-Greenberg, Goni, additional, Senter, Katharine, additional, Sharshir, Moh’d A., additional, Rusnak, Vadym V., additional, Ali, Muhammad Imran, additional, Peters, Terri, additional, Hughes, Kathy, additional, Bansal, Anip, additional, Podoll, Amber S., additional, Chonchol, Michel, additional, Sharma, Sunita, additional, Burnham, Ellen L., additional, Rashidi, Arash, additional, Hejal, Rana, additional, Judd, Eric, additional, Latta, Laura, additional, Tolwani, Ashita, additional, Albertson, Timothy E., additional, Adams, Jason Y., additional, Chang, Steven Y., additional, Beutler, Rebecca M., additional, Monica, Santa, additional, Schulze, Carl E., additional, Macedo, Etienne, additional, Rhee, Harin, additional, Liu, Kathleen D., additional, Jotwani, Vasantha K., additional, Koyner, Jay L., additional, Shah, Chintan V., additional, Jaikaransingh, Vishal, additional, Toth-Manikowski, Stephanie M., additional, Joo, Min J., additional, Lash, James P., additional, Neyra, Javier A., additional, Chaaban, Nourhan, additional, Iardino, Alfredo, additional, Au, Elizabeth H., additional, Sharma, Jill H., additional, Sosa, Marie Anne, additional, Taldone, Sabrina, additional, Contreras, Gabriel, additional, De La Zerda, David, additional, Fornoni, Alessia, additional, Gershengorn, Hayley B., additional, Hayek, Salim S., additional, Blakely, Pennelope, additional, Berlin, Hanna, additional, Azam, Tariq U., additional, Shadid, Husam, additional, Pan, Michael, additional, O’Hayer, Patrick, additional, Meloche, Chelsea, additional, Feroze, Rafey, additional, Kaakati, Rayan, additional, Perry, Danny, additional, Bitar, Abbas, additional, Anderson, Elizabeth, additional, Padalia, Kishan J., additional, Launius, Christopher, additional, Donnelly, John P., additional, Admon, Andrew J., additional, Flythe, Jennifer E., additional, Tugman, Matthew J., additional, Chang, Emily H., additional, Brown, Brent R., additional, Leonberg-Yoo, Amanda K., additional, Spiardi, Ryan C., additional, Miano, Todd A., additional, Roche, Meaghan S., additional, Vasquez, Charles R., additional, Bansal, Amar D., additional, Ernecoff, Natalie C., additional, Kapoor, Sanjana, additional, Verma, Siddharth, additional, Chen, Huiwen, additional, Kovesdy, Csaba P., additional, Molnar, Miklos Z., additional, Azhar, Ambreen, additional, Hedayati, S. Susan, additional, Nadamuni, Mridula V., additional, Shastri, Shani, additional, Willett, Duwayne L., additional, Short, Samuel A. P., additional, Renaghan, Amanda D., additional, Enfield, Kyle B., additional, Bhatraju, Pavan K., additional, Malik, A. Bilal, additional, Semler, Matthew W., additional, Vijayan, Anitha, additional, Joy, Christina Mariyam, additional, Li, Tingting, additional, Goldberg, Seth, additional, Kao, Patricia F., additional, Schumaker, Greg L., additional, Goyal, Nitender, additional, Faugno, Anthony J., additional, Hsu, Caroline M., additional, Tariq, Asma, additional, Meyer, Leah, additional, Kshirsagar, Ravi K., additional, Weiner, Daniel E., additional, Christov, Marta, additional, Griffiths, Jennifer, additional, Gupta, Sanjeev, additional, Kapoor, Aromma, additional, Wilson, Perry, additional, Arora, Tanima, additional, and Ugwuowo, Ugochukwu, additional
Published: 2021
Full Text: View/download PDF

27. Soluble Urokinase Plasminogen Activator Receptor and Venous Thromboembolism in COVID-19.

Author: Shengyuan Luo, Vasbinder, Alexi, Du-Fay- de- Lavallaz, Jeanne M., D. Gomez, Joanne Michelle, Suboc, Tisha, Anderson, Elizabeth, Tekumulla, Annika, Shadid, Husam, Berlin, Hanna, Pan, Michael, Azam, Tariq U., Khaleel, Ibrahim, Padalia, Kishan, Meloche, Chelsea, O’Hayer, Patrick, Catalan, Tonimarie, Blakely, Pennelope, Launius, Christopher, Amadi, Kingsley-Michael, and Pop-Busui, Rodica
Published: 2022
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28. Representation of Black patients in heart failure clinical trials

Author: Azam, Tariq U., primary and Colvin, Monica M., additional
Published: 2021
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29. Thrombosis, Bleeding, and the Observational Effect of Early Therapeutic Anticoagulation on Survival in Critically Ill Patients With COVID-19

Author: Al-Samkari, Hanny, primary, Gupta, Shruti, additional, Leaf, Rebecca Karp, additional, Wang, Wei, additional, Rosovsky, Rachel P., additional, Brenner, Samantha K., additional, Hayek, Salim S., additional, Berlin, Hanna, additional, Kapoor, Rajat, additional, Shaefi, Shahzad, additional, Melamed, Michal L., additional, Sutherland, Anne, additional, Radbel, Jared, additional, Green, Adam, additional, Garibaldi, Brian T., additional, Srivastava, Anand, additional, Leonberg-Yoo, Amanda, additional, Shehata, Alexandre M., additional, Flythe, Jennifer E., additional, Rashidi, Arash, additional, Goyal, Nitender, additional, Chan, Lili, additional, Mathews, Kusum S., additional, Hedayati, S. Susan, additional, Dy, Rajany, additional, Toth-Manikowski, Stephanie M., additional, Zhang, Jingjing, additional, Mallappallil, Mary, additional, Redfern, Roberta E., additional, Bansal, Amar D., additional, Short, Samuel A.P., additional, Vangel, Mark G., additional, Admon, Andrew J., additional, Semler, Matthew W., additional, Bauer, Kenneth A., additional, Hernán, Miguel A., additional, Leaf, David E., additional, Walther, Carl P., additional, Anumudu, Samaya J., additional, Arunthamakun, Justin, additional, Kopecky, Kathleen F., additional, Milligan, Gregory P., additional, McCullough, Peter A., additional, Nguyen, Thuy-Duyen, additional, Krajewski, Megan L., additional, Shankar, Sidharth, additional, Pannu, Ameeka, additional, Valencia, Juan D., additional, Waikar, Sushrut S., additional, Kibbelaar, Zoe A., additional, Athavale, Ambarish M., additional, Hart, Peter, additional, Upadhyay, Shristi, additional, Vohra, Ishaan, additional, Oyintayo, Ajiboye, additional, Rachoin, Jean-Sebastien, additional, Schorr, Christa A., additional, Shea, Lisa, additional, Edmonston, Daniel L., additional, Mosher, Christopher L., additional, Cohen, Zaza, additional, Allusson, Valerie, additional, Bambrick-Santoyo, Gabriela, additional, aain Bhatti, Noor ul, additional, Mehta, Bijal, additional, Williams, Aquino, additional, Walters, Patricia, additional, Go, Ronaldo C., additional, Rose, Keith M., additional, Zhou, Amy M., additional, Kim, Ethan C., additional, Lisk, Rebecca, additional, Coca, Steven G., additional, Altman, Deena R., additional, Saha, Aparna, additional, Soh, Howard, additional, Wen, Huei Hsun, additional, Bose, Sonali, additional, Leven, Emily A., additional, Wang, Jing G., additional, Mosoyan, Gohar, additional, Pattharanitima, Pattharawin, additional, Gallagher, Emily J., additional, Friedman, Allon N., additional, Guirguis, John, additional, Meshberger, Christopher, additional, Kelly, Katherine J., additional, Parikh, Chirag R., additional, Corona-Villalobos, Celia P., additional, Wen, Yumeng, additional, Menez, Steven, additional, Malik, Rubab F., additional, Cervantes, Carmen Elena, additional, Gautam, Samir C., additional, Mallappallil, Mary C., additional, Ouyang, Jie, additional, John, Sabu, additional, Yap, Ernie, additional, Melaku, Yohannes, additional, Mohamed, Ibrahim, additional, Bajracharya, Siddhartha, additional, Puri, Isha, additional, Thaxton, Mariah, additional, Bhattacharya, Jyotsna, additional, Wagner, John, additional, Boudourakis, Leon, additional, Nguyen, H. Bryant, additional, Ahoubim, Afshin, additional, Thomas, Leslie F., additional, Sirganagari, Dheeraj Reddy, additional, Guru, Pramod K., additional, Zhou, Yan, additional, Bergl, Paul A., additional, Rodriguez, Jesus, additional, Shah, Jatan A., additional, Gupta, Mrigank S., additional, Kumar, Princy N., additional, Lazarous, Deepa G., additional, Kassaye, Seble G., additional, Johns, Tanya S., additional, Mocerino, Ryan, additional, Prudhvi, Kalyan, additional, Zhu, Denzel, additional, Levy, Rebecca V., additional, Azzi, Yorg, additional, Fisher, Molly, additional, Yunes, Milagros, additional, Sedaliu, Kaltrina, additional, Golestaneh, Ladan, additional, Brogan, Maureen, additional, Thakkar, Jyotsana, additional, Kumar, Neelja, additional, Ross, Michael J., additional, Chang, Michael, additional, Raichoudhury, Ritesh, additional, Athreya, Akshay, additional, Farag, Mohamed, additional, Schenck, Edward J., additional, Cho, Soo Jung, additional, Plataki, Maria, additional, Alvarez-Mulett, Sergio L., additional, Gomez-Escobar, Luis G., additional, Pan, Di, additional, Lee, Stefi, additional, Krishnan, Jamuna, additional, Whalen, William, additional, Charytan, David, additional, Macina, Ashley, additional, Leidner, Alexander S., additional, Martinez, Carlos, additional, Kruser, Jacqueline M., additional, Wunderink, Richard G., additional, Hodakowski, Alexander J., additional, Q. Velez, Juan Carlos, additional, Price-Haywood, Eboni G., additional, Matute-Trochez, Luis A., additional, Hasty, Anna E., additional, Mohamed, Muner M.B., additional, Avasare, Rupali S., additional, Zonies, David, additional, Al-Samkari, Hanny, additional, Rosovsky, Rachel, additional, Sise, Meghan E., additional, Newman, Erik T., additional, Omar, Samah Abu, additional, Pokharel, Kapil K., additional, Sharma, Shreyak, additional, Singh, Harkarandeep, additional, Correa, Simon, additional, Shaukat, Tanveer, additional, Kamal, Omer, additional, Lee, Meghan, additional, Strohbehn, Ian A., additional, Li, Jiahua, additional, Mueller, Ariel L., additional, Cairl, Nicholas S., additional, Naimy, Gabriel, additional, Abu-Saif, Abeer, additional, Hall, Danyell, additional, Bickley, Laura, additional, Rowan, Chris, additional, Madhani-Lovely, Farah, additional, Peev, Vasil, additional, Reiser, Jochen, additional, Byun, John J., additional, Vissing, Andrew, additional, Kapania, Esha M., additional, Post, Zoe, additional, Patel, Nilam P., additional, Hermes, Joy-Marie, additional, Sutherland, Anne K., additional, Patrawalla, Amee, additional, Finkel, Diana G., additional, Danek, Barbara A., additional, Arikapudi, Sowminya, additional, Paer, Jeffrey M., additional, Cangialosi, Peter, additional, Liotta, Mark, additional, Puri, Sonika, additional, Sunderram, Jag, additional, Scharf, Matthew T., additional, Ahmed, Ayesha, additional, Berim, Ilya, additional, Vatson, Jayanth S., additional, Karp, George, additional, Anand, Shuchi, additional, Levitt, Joseph E., additional, Garcia, Pablo, additional, Boyle, Suzanne M., additional, Song, Rui, additional, Woo, Sang Hoon, additional, Deng, Xiaoying, additional, Katz-Greenberg, Goni, additional, Sharshir, Moh'd A., additional, Rusnak, Vadym V., additional, Ali, Muhammad Imran, additional, Bansal, Anip, additional, Podoll, Amber S., additional, Chonchol, Michel, additional, Sharma, Sunita, additional, Burnham, Ellen L., additional, Hejal, Rana, additional, Judd, Eric, additional, Latta, Laura, additional, Tolwani, Ashita, additional, Albertson, Timothy E., additional, Adams, Jason Y., additional, Chang, Steven Y., additional, Beutler, Rebecca M., additional, Schulze, Carl E., additional, Macedo, Etienne, additional, Rhee, Harin, additional, Liu, Kathleen D., additional, Jotwani, Vasantha K., additional, Koyner, Jay L., additional, Shah, Chintan V., additional, Jaikaransingh, Vishal, additional, Joo, Min J., additional, Lash, James P., additional, Neyra, Javier A., additional, Chaaban, Nourhan, additional, Elias, Madona, additional, Ahmad, Yahya, additional, Iardino, Alfredo, additional, Au, Elizabeth H., additional, Sharma, Jill H., additional, Sosa, Marie Anne, additional, Taldone, Sabrina, additional, Contreras, Gabriel, additional, De La Zerda, David, additional, Gershengorn, Hayley B., additional, Fornoni, Alessia, additional, Blakely, Pennelope, additional, Azam, Tariq U., additional, Shadid, Husam, additional, Pan, Michael, additional, O’Hayer, Patrick, additional, Meloche, Chelsea, additional, Feroze, Rafey, additional, Padalia, Kishan J., additional, Leya, Jeff, additional, Donnelly, John P., additional, Tugman, Matthew J., additional, Chang, Emily H., additional, Brown, Brent R., additional, Leonberg-Yoo, Amanda K., additional, Spiardi, Ryan C., additional, Miano, Todd A., additional, Roche, Meaghan S., additional, Vasquez, Charles R., additional, Ernecoff, Natalie C., additional, Kapoor, Sanjana, additional, Verma, Siddharth, additional, Chen, Huiwen, additional, Kovesdy, Csaba P., additional, Molnar, Miklos Z., additional, Azhar, Ambreen, additional, Nadamuni, Mridula V., additional, Shastri, Shani, additional, Willett, Duwayne L., additional, Renaghan, Amanda D., additional, Enfield, Kyle B., additional, Bhatraju, Pavan K., additional, Malik, A. Bilal, additional, Vijayan, Anitha, additional, Joy, Christina Mariyam, additional, Li, Tingting, additional, Goldberg, Seth, additional, Kao, Patricia F., additional, Schumaker, Greg L., additional, Faugno, Anthony J., additional, Hsu, Caroline M., additional, Tariq, Asma, additional, Meyer, Leah, additional, Kshirsagar, Ravi K., additional, Weiner, Daniel E., additional, Christov, Marta, additional, Griffiths, Jennifer, additional, Gupta, Sanjeev, additional, Kapoor, Aromma, additional, Chugh, Savneek, additional, Wilson, Perry, additional, Arora, Tanima, additional, and Ugwuowo, Ugochukwu, additional
Published: 2021
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30. CARDIOVASCULAR DISEASE AND OUTCOMES IN CRITICALLY ILL PATIENTS WITH COVID-19: A STOP-COVID ANCILLARY

Author: Meloche, Chelsea, primary, Azam, Tariq U., additional, Anderson, Elizabeth, additional, Shadid, Husam, additional, Berlin, Hanna, additional, Pan, Michael, additional, Feroze, Rafey, additional, O’Hayer, Patrick, additional, Bitar, Abbas, additional, Padalia, Kishan, additional, Michaud, Erinleigh, additional, Launius, Christopher, additional, Blakely, Penelope, additional, Gupta, Shruti, additional, Leaf, David E., additional, and Hayek, Salim, additional
Published: 2021
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31. Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and Outcomes in Patients Hospitalized for COVID-19

Author: Pan, Michael Vasbinder, Alexi Anderson, Elizabeth Catalan, Toniemarie Shadid, Husam R. Berlin, Hanna Padalia, Kishan and O'Hayer, Patrick Meloche, Chelsea Azam, Tariq U. and Khaleel, Ibrahim Michaud, Erinleigh Blakely, Pennelope and Bitar, Abbas Huang, Yiyuan Zhao, Lili Pop-Busui, Rodica and Loosen, Sven H. Chalkias, Athanasios Tacke, Frank and Giamarellos-Bourboulis, Evangelos J. Reiser, Jochen Eugen-Olsen, Jesper Hayek, Salim S. ISIC Grp
Subjects: cardiovascular diseases
Abstract: BACKGROUND: Use of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers (ACEi/ARB) is thought to affect COVID-19 through modulating levels of angiotensin-converting enzyme 2, the cell entry receptor for SARS-CoV2. We sought to assess the association between ACEi/ARB, biomarkers of inflammation, and outcomes in patients hospitalized for COVID-19. METHODS AND RESULTS: We leveraged the ISIC (International Study of Inflammation in COVID-19), identified patients admitted for symptomatic COVID-19 between February 1, 2020 and June 1, 2021 for COVID-19, and examined the association between in-hospital ACEi/ARB use and all-cause death, need for ventilation, and need for dialysis. We estimated the causal effect of ACEi/ARB on the composite outcomes using marginal structural models accounting for serial blood pressure and serum creatinine measures. Of 2044 patients in ISIC, 1686 patients met inclusion criteria, of whom 398 (23.6%) patients who were previously on ACEi/ARB received at least 1 dose during their hospitalization for COVID-19. There were 215 deaths, 407 patients requiring mechanical ventilation, and 124 patients who required dialysis during their hospitalization. Prior ACEi/ARB use was associated with lower levels of soluble urokinase plasminogen activator receptor and C-reactive protein. In multivariable analysis, in-hospital ACEi/ARB use was associated with a lower risk of the composite outcome of in-hospital death, mechanical ventilation, or dialysis (adjusted hazard ratio 0.49, 95% CI [0.36- -0.65]). CONCLUSIONS: In patients hospitalized for COVID-19, ACEi/ARB use was associated with lower levels of inflammation and lower risk of in-hospital outcomes. Clinical trials will define the role of ACEi/ARB in the treatment of COVID-19.
Published: 2021

32. Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19

Author: Gupta, Shruti, Wang, Wei, Hayek, Salim S., Chan, Lili, Mathews, Kusum S., Melamed, Michal L., Brenner, Samantha K., Leonberg-Yoo, Amanda, Schenck, Edward J., Radbel, Jared, Reiser, Jochen, Bansal, Anip, Srivastava, Anand, Zhou, Yan, Finkel, Diana, Green, Adam, Mallappallil, Mary, Faugno, Anthony J., Zhang, Jingjing, Velez, Juan Carlos Q., Shaefi, Shahzad, Parikh, Chirag R., Charytan, David M., Athavale, Ambarish M., Friedman, Allon N., Redfern, Roberta E., Short, Samuel A. P., Correa, Simon, Pokharel, Kapil K., Admon, Andrew J., Donnelly, John P., Gershengorn, Hayley B., Douin, David J., Semler, Matthew W., Hernán, Miguel A., Leaf, David E., Walther, Carl P., Anumudu, Samaya J., Arunthamakun, Justin, Kopecky, Kathleen F., Milligan, Gregory P., McCullough, Peter A., Nguyen, Thuy-Duyen, Krajewski, Megan L., Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D., Waikar, Sushrut S., Kibbelaar, Zoe A., Hart, Peter, Upadhyay, Shristi, Vohra, Ishaan, Oyintayo, Ajiboye, Rachoin, Jean-Sebastien, Schorr, Christa A., Shea, Lisa, Edmonston, Daniel L., Mosher, Christopher L., Shehata, Alexandre M., Cohen, Zaza, Allusson, Valerie, Bambrick-Santoyo, Gabriela, Bhatti, Noor ul aain, Mehta, Bijal, Williams, Aquino, Walters, Patricia, Go, Ronaldo C., Rose, Keith M., Lisk, Rebecca, Zhou, Amy M., Kim, Ethan C., Coca, Steven G., Altman, Deena R., Saha, Aparna, Soh, Howard, Wen, Huei Hsun, Bose, Sonali, Leven, Emily A., Wang, Jing G., Mosoyan, Gohar, Nadkarni, Girish N., Pattharanitima, Pattharawin, Gallagher, Emily J., Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Kelly, Katherine J., Garibaldi, Brian T., Corona-Villalobos, Celia P., Wen, Yumeng, Menez, Steven, Malik, Rubab F., Cervantes, Carmen Elena, Gautam, Samir C., Mallappallil, Mary C., Ouyang, Jie, John, Sabu, Yap, Ernie, Melaku, Yohannes, Mohamed, Ibrahim, Bajracharya, Siddhartha, Puri, Isha, Thaxton, Mariah, Bhattacharya, Jyotsna, Wagner, John, Boudourakis, Leon, Nguyen, H. Bryant, Ahoubim, Afshin, Kashani, Kianoush, Tehranian, Shahrzad, Thomas, Leslie F., Sirganagari, Dheeraj Reddy, Guru, Pramod K., Bergl, Paul A., Rodriguez, Jesus, Shah, Jatan A., Gupta, Mrigank S., Kumar, Princy N., Lazarous, Deepa G., Kassaye, Seble G., Johns, Tanya S., Mocerino, Ryan, Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V., Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Kumar, Neelja, Chang, Michael, Thakkar, Jyotsana, Raichoudhury, Ritesh, Athreya, Akshay, Farag, Mohamed, Cho, Soo Jung, Plataki, Maria, Alvarez-Mulett, Sergio L., Gomez-Escobar, Luis G., Pan, Di, Lee, Stefi, Krishnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Chaudhry, Sobaata, Wu, Benjamin, Modersitzki, Frank, Leidner, Alexander S., Martinez, Carlos, Kruser, Jacqueline M., Wunderink, Richard G., Hodakowski, Alexander J., Price-Haywood, Eboni G., Matute-Trochez, Luis A., Hasty, Anna E., Mohamed, Muner MB., Avasare, Rupali S., Zonies, David, Sise, Meghan E., Newman, Erik T., Omar, Samah Abu, Sharma, Shreyak, Singh, Harkarandeep, Shaukat, Tanveer, Kamal, Omer, Yang, Heather, Boateng, Jeffery O., Lee, Meghan, Strohbehn, Ian A., Li, Jiahua, Mueller, Ariel L., Cairl, Nicholas S., Naimy, Gabriel, Abu-Saif, Abeer, Hall, Danyell, Bickley, Laura, Rowan, Chris, Madhani-Lovely, Farah, Peev, Vasil, Byun, John J., Vissing, Andrew, Kapania, Esha M., Post, Zoe, Patel, Nilam P., Hermes, Joy-Marie, Sutherland, Anne K., Patrawalla, Amee, Finkel, Diana G., Danek, Barbara A., Arikapudi, Sowminya, Paer, Jeffrey M., Cangialosi, Peter, Liotta, Mark, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T., Ahmed, Ayesha, Berim, Ilya, Vatson, Jayanth S., Anand, Shuchi, Levitt, Joseph E., Garcia, Pablo, Boyle, Suzanne M., Song, Rui, Arif, Ali, Woo, Sang Hoon, Deng, Xiaoying, Katz-Greenberg, Goni, Senter, Katharine, Sharshir, Moh’d A., Rusnak, Vadym V., Ali, Muhammad Imran, Peters, Terri, Hughes, Kathy, Podoll, Amber S., Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L., Rashidi, Arash, Hejal, Rana, Judd, Eric, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E., Adams, Jason Y., Chang, Steven Y., Beutler, Rebecca M., Schulze, Carl E., Macedo, Etienne, Rhee, Harin, Liu, Kathleen D., Jotwani, Vasantha K., Koyner, Jay L., Shah, Chintan V., Jaikaransingh, Vishal, Toth-Manikowski, Stephanie M., Joo, Min J., Lash, James P., Neyra, Javier A., Chaaban, Nourhan, Elias, Madona, Ahmad, Yahya, Iardino, Alfredo, Au, Elizabeth H., Sharma, Jill H., Sosa, Marie Anne, Taldone, Sabrina, Contreras, Gabriel, Zerda, David De La, Fornoni, Alessia, Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U., Shadid, Husam, Pan, Michael, O’ Hayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Padalia, Kishan J., Bitar, Abbas, Leya, Jeff, Flythe, Jennifer E., Tugman, Matthew J., Chang, Emily H., Brown, Brent R., Leonberg-Yoo, Amanda K., Spiardi, Ryan C., Miano, Todd A., Roche, Meaghan S., Vasquez, Charles R., Bansal, Amar D., Ernecoff, Natalie C., Kapoor, Sanjana, Verma, Siddharth, Chen, Huiwen, Kovesdy, Csaba P., Molnar, Miklos Z., Azhar, Ambreen, Hedayati, S. Susan, Nadamuni, Mridula V., Shastri, Shani, Willett, Duwayne L., Short, Samuel A.P., Renaghan, Amanda D., Enfield, Kyle B., Bhatraju, Pavan K., Malik, A. Bilal, Vijayan, Anitha, Joy, Christina Mariyam, Li, Tingting, Goldberg, Seth, Kao, Patricia F., Schumaker, Greg L., Goyal, Nitender, Hsu, Caroline M., Tariq, Asma, Meyer, Leah, Kshirsagar, Ravi K., Jose, Aju, Weiner, Daniel E., Christov, Marta, Griffiths, Jennifer, Gupta, Sanjeev, Kapoor, Aromma, Wilson, Perry, Arora, Tanima, and Ugwuowo, Ugochukwu
Subjects: musculoskeletal diseases, medicine.medical_specialty, Population, 01 natural sciences, law.invention, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tocilizumab, Interquartile range, law, Intensive care, Internal medicine, Fraction of inspired oxygen, medicine, Internal Medicine, 030212 general & internal medicine, 0101 mathematics, education, Original Investigation, education.field_of_study, business.industry, 010102 general mathematics, Hazard ratio, Intensive care unit, chemistry, business, Cohort study
Abstract: IMPORTANCE: Therapies that improve survival in critically ill patients with coronavirus disease 2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 receptor, may counteract the inflammatory cytokine release syndrome in patients with severe COVID-19 illness. OBJECTIVE: To test whether tocilizumab decreases mortality in this population. DESIGN, SETTING, AND PARTICIPANTS: The data for this study were derived from a multicenter cohort study of 4485 adults with COVID-19 admitted to participating intensive care units (ICUs) at 68 hospitals across the US from March 4 to May 10, 2020. Critically ill adults with COVID-19 were categorized according to whether they received or did not receive tocilizumab in the first 2 days of admission to the ICU. Data were collected retrospectively until June 12, 2020. A Cox regression model with inverse probability weighting was used to adjust for confounding. EXPOSURES: Treatment with tocilizumab in the first 2 days of ICU admission. MAIN OUTCOMES AND MEASURES: Time to death, compared via hazard ratios (HRs), and 30-day mortality, compared via risk differences. RESULTS: Among the 3924 patients included in the analysis (2464 male [62.8%]; median age, 62 [interquartile range {IQR}, 52-71] years), 433 (11.0%) received tocilizumab in the first 2 days of ICU admission. Patients treated with tocilizumab were younger (median age, 58 [IQR, 48-65] vs 63 [IQR, 52-72] years) and had a higher prevalence of hypoxemia on ICU admission (205 of 433 [47.3%] vs 1322 of 3491 [37.9%] with mechanical ventilation and a ratio of partial pressure of arterial oxygen to fraction of inspired oxygen of
Published: 2021
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33. Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States

Author: Flythe, Jennifer E., primary, Assimon, Magdalene M., additional, Tugman, Matthew J., additional, Chang, Emily H., additional, Gupta, Shruti, additional, Shah, Jatan, additional, Sosa, Marie Anne, additional, Renaghan, Amanda DeMauro, additional, Melamed, Michal L., additional, Wilson, F. Perry, additional, Neyra, Javier A., additional, Rashidi, Arash, additional, Boyle, Suzanne M., additional, Anand, Shuchi, additional, Christov, Marta, additional, Thomas, Leslie F., additional, Edmonston, Daniel, additional, Leaf, David E., additional, Walther, Carl P., additional, Anumudu, Samaya J., additional, Arunthamakun, Justin, additional, Kopecky, Kathleen F., additional, Milligan, Gregory P., additional, McCullough, Peter A., additional, Nguyen, Thuy-Duyen, additional, Shaefi, Shahzad, additional, Krajewski, Megan L., additional, Shankar, Sidharth, additional, Pannu, Ameeka, additional, Valencia, Juan D., additional, Waikar, Sushrut S., additional, Kibbelaar, Zoe A., additional, Athavale, Ambarish M., additional, Hart, Peter, additional, Upadhyay, Shristi, additional, Vohra, Ishaan, additional, Green, Adam, additional, Rachoin, Jean-Sebastien, additional, Schorr, Christa A., additional, Shea, Lisa, additional, Edmonston, Daniel L., additional, Mosher, Christopher L., additional, Shehata, Alexandre M., additional, Cohen, Zaza, additional, Allusson, Valerie, additional, Bambrick-Santoyo, Gabriela, additional, Bhatti, Noor ul aain, additional, Mehta, Bijal, additional, Williams, Aquino, additional, Brenner, Samantha K., additional, Walters, Patricia, additional, Go, Ronaldo C., additional, Rose, Keith M., additional, Chan, Lili, additional, Mathews, Kusum S., additional, Coca, Steven G., additional, Altman, Deena R., additional, Saha, Aparna, additional, Soh, Howard, additional, Wen, Huei Hsun, additional, Bose, Sonali, additional, Leven, Emily A., additional, Wang, Jing G., additional, Mosoyan, Gohar, additional, Nadkarni, Girish N., additional, Pattharanitima, Pattharawin, additional, Gallagher, Emily J., additional, Friedman, Allon N., additional, Guirguis, John, additional, Kapoor, Rajat, additional, Meshberger, Christopher, additional, Kelly, Katherine J., additional, Parikh, Chirag R., additional, Garibaldi, Brian T., additional, Corona-Villalobos, Celia P., additional, Wen, Yumeng, additional, Menez, Steven, additional, Malik, Rubab F., additional, Cervantes, Carmen Elena, additional, Gautam, Samir C., additional, Mallappallil, Mary C., additional, Ouyang, Jie, additional, John, Sabu, additional, Yap, Ernie, additional, Melaku, Yohannes, additional, Mohamed, Ibrahim, additional, Bajracharya, Siddhartha, additional, Puri, Isha, additional, Thaxton, Mariah, additional, Bhattacharya, Jyotsna, additional, Wagner, John, additional, Boudourakis, Leon, additional, Nguyen, H. Bryant, additional, Ahoubim, Afshin, additional, Kashani, Kianoush, additional, Tehranian, Shahrzad, additional, Sirganagari, Dheeraj Reddy, additional, Guru, Pramod K., additional, Zhou, Yan, additional, Bergl, Paul A., additional, Rodriguez, Jesus, additional, Shah, Jatan A., additional, Gupta, Mrigank S., additional, Kumar, Princy N., additional, Lazarous, Deepa G., additional, Kassaye, Seble G., additional, Johns, Tanya S., additional, Mocerino, Ryan, additional, Prudhvi, Kalyan, additional, Zhu, Denzel, additional, Levy, Rebecca V., additional, Azzi, Yorg, additional, Fisher, Molly, additional, Yunes, Milagros, additional, Sedaliu, Kaltrina, additional, Golestaneh, Ladan, additional, Brogan, Maureen, additional, Kumar, Neelja, additional, Chang, Michael, additional, Thakkar, Jyotsana, additional, Raichoudhury, Ritesh, additional, Athreya, Akshay, additional, Farag, Mohamed, additional, Schenck, Edward J., additional, Cho, Soo Jung, additional, Plataki, Maria, additional, Alvarez-Mulett, Sergio L., additional, Gomez-Escobar, Luis G., additional, Pan, Di, additional, Lee, Stefi, additional, Krishnan, Jamuna, additional, Whalen, William, additional, Charytan, David, additional, Macina, Ashley, additional, Chaudhry, Sobaata, additional, Wu, Benjamin, additional, Modersitzki, Frank, additional, Srivastava, Anand, additional, Leidner, Alexander S., additional, Martinez, Carlos, additional, Kruser, Jacqueline M., additional, Wunderink, Richard G., additional, Hodakowski, Alexander J., additional, Velez, Juan Carlos Q., additional, Price-Haywood, Eboni G., additional, Matute-Trochez, Luis A., additional, Hasty, Anna E., additional, Mohamed, Muner M.B., additional, Avasare, Rupali S., additional, Zonies, David, additional, Sise, Meghan E., additional, Newman, Erik T., additional, Abu Omar, Samah, additional, Pokharel, Kapil K., additional, Sharma, Shreyak, additional, Singh, Harkarandeep, additional, Correa, Simon, additional, Shaukat, Tanveer, additional, Kamal, Omer, additional, Wang, Wei, additional, Yang, Heather, additional, Boateng, Jeffery O., additional, Lee, Meghan, additional, Strohbehn, Ian A., additional, Li, Jiahua, additional, Mueller, Ariel L., additional, Redfern, Roberta, additional, Cairl, Nicholas S., additional, Naimy, Gabriel, additional, Abu-Saif, Abeer, additional, Hall, Danyell, additional, Bickley, Laura, additional, Rowan, Chris, additional, Madhani-Lovely, Farah, additional, Peev, Vasil, additional, Reiser, Jochen, additional, Byun, John J., additional, Vissing, Andrew, additional, Kapania, Esha M., additional, Post, Zoe, additional, Patel, Nilam P., additional, Hermes, Joy-Marie, additional, Sutherland, Anne K., additional, Patrawalla, Amee, additional, Finkel, Diana G., additional, Danek, Barbara A., additional, Arikapudi, Sowminya, additional, Paer, Jeffrey M., additional, Cangialosi, Peter, additional, Liotta, Mark, additional, Radbel, Jared, additional, Puri, Sonika, additional, Sunderram, Jag, additional, Scharf, Matthew T., additional, Ahmed, Ayesha, additional, Berim, Ilya, additional, Vatson, Jayanth S., additional, Levitt, Joseph E., additional, Garcia, Pablo, additional, Song, Rui, additional, Zhang, Jingjing, additional, Woo, Sang Hoon, additional, Deng, Xiaoying, additional, Katz-Greenberg, Goni, additional, Senter, Katharine, additional, Sharshir, Moh’d A., additional, Rusnak, Vadym V., additional, Ali, Muhammad Imran, additional, Bansal, Anip, additional, Podoll, Amber S., additional, Chonchol, Michel, additional, Sharma, Sunita, additional, Burnham, Ellen L., additional, Hejal, Rana, additional, Judd, Eric, additional, Latta, Laura, additional, Tolwani, Ashita, additional, Albertson, Timothy E., additional, Adams, Jason Y., additional, Reagan, Ronald, additional, Chang, Steven Y., additional, Beutler, Rebecca M., additional, Monica, Santa, additional, Schulze, Carl E., additional, Macedo, Etienne, additional, Rhee, Harin, additional, Liu, Kathleen D., additional, Jotwani, Vasantha K., additional, Koyner, Jay L., additional, Kunczt, Alissa, additional, Shah, Chintan V., additional, Jaikaransingh, Vishal, additional, Toth-Manikowski, Stephanie M., additional, Joo, Min J., additional, Lash, James P., additional, Chaaban, Nourhan, additional, Dy, Rajany, additional, Iardino, Alfredo, additional, Au, Elizabeth H., additional, Sharma, Jill H., additional, Taldone, Sabrina, additional, Contreras, Gabriel, additional, De La Zerda, David, additional, Gershengorn, Hayley B., additional, Hayek, Salim S., additional, Blakely, Pennelope, additional, Berlin, Hanna, additional, Azam, Tariq U., additional, Shadid, Husam, additional, Pan, Michael, additional, Hayer, Patrick O’, additional, Meloche, Chelsea, additional, Feroze, Rafey, additional, Kaakati, Rayan, additional, Perry, Danny, additional, Bitar, Abbas, additional, Anderson, Elizabeth, additional, Padalia, Kishan J., additional, Donnelly, John P., additional, Admon, Andrew J., additional, Flythe, Jennifer E., additional, Brown, Brent R., additional, Leonberg-Yoo, Amanda K., additional, Spiardi, Ryan C., additional, Miano, Todd A., additional, Roche, Meaghan S., additional, Vasquez, Charles R., additional, Bansal, Amar D., additional, Ernecoff, Natalie C., additional, Kapoor, Sanjana, additional, Verma, Siddharth, additional, Chen, Huiwen, additional, Kovesdy, Csaba P., additional, Molnar, Miklos Z., additional, Azhar, Ambreen, additional, Hedayati, S. Susan, additional, Nadamuni, Mridula V., additional, Shastri, Shani, additional, Willett, Duwayne L., additional, Short, Samuel A.P., additional, Renaghan, Amanda D., additional, Enfield, Kyle B., additional, Bhatraju, Pavan K., additional, Malik, A. Bilal, additional, Semler, Matthew W., additional, Vijayan, Anitha, additional, Mariyam Joy, Christina, additional, Li, Tingting, additional, Goldberg, Seth, additional, Kao, Patricia F., additional, Schumaker, Greg L., additional, Goyal, Nitender, additional, Faugno, Anthony J., additional, Hsu, Caroline M., additional, Tariq, Asma, additional, Meyer, Leah, additional, Kshirsagar, Ravi K., additional, Weiner, Daniel E., additional, Jose, Aju, additional, Griffiths, Jennifer, additional, Gupta, Sanjeev, additional, Kapoor, Aromma, additional, Wilson, Perry, additional, Arora, Tanima, additional, and Ugwuowo, Ugochukwu, additional
Published: 2021
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34. Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI

Author: Azam, Tariq U, Shadid, Husam R, Blakely, Pennelope, O'Hayer, Patrick, Berlin, Hanna, Pan, Michael, Zhao, Peiyao, Zhao, Lili, Pennathur, Subramaniam, Pop-Busui, Rodica, Altintas, Izzet, Tingleff, Jens, Stauning, Marius A, Andersen, Ove, Adami, Maria-Evangelia, Solomonidi, Nicky, Tsilika, Maria, Tober-Lau, Pinkus, Arnaoutoglou, Eleni, Keitel, Verena, Tacke, Frank, Chalkias, Athanasios, Loosen, Sven H, Giamarellos-Bourboulis, Evangelos J, Eugen-Olsen, Jesper, Reiser, Jochen, Hayek, Salim S, Azam, Tariq U, Shadid, Husam R, Blakely, Pennelope, O'Hayer, Patrick, Berlin, Hanna, Pan, Michael, Zhao, Peiyao, Zhao, Lili, Pennathur, Subramaniam, Pop-Busui, Rodica, Altintas, Izzet, Tingleff, Jens, Stauning, Marius A, Andersen, Ove, Adami, Maria-Evangelia, Solomonidi, Nicky, Tsilika, Maria, Tober-Lau, Pinkus, Arnaoutoglou, Eleni, Keitel, Verena, Tacke, Frank, Chalkias, Athanasios, Loosen, Sven H, Giamarellos-Bourboulis, Evangelos J, Eugen-Olsen, Jesper, Reiser, Jochen, and Hayek, Salim S
Abstract: BACKGROUND: AKI commonly occurs in patients with coronavirus disease 2019 (COVID-19). Its pathogenesis is poorly understood. The urokinase receptor system is a key regulator of the intersection between inflammation, immunity, and coagulation, and soluble urokinase plasminogen activator receptor (suPAR) has been identified as an immunologic risk factor for AKI. Whether suPAR is associated with COVID-19-related AKI is unknown.METHODS: In a multinational observational study of adult patients hospitalized for COVID-19, we measured suPAR levels in plasma samples from 352 adult patients that had been collected within 48 hours of admission. We examined the association between suPAR levels and incident in-hospital AKI.RESULTS: Of the 352 patients (57.4% were male, 13.9% were black, and mean age was 61 years), 91 (25.9%) developed AKI during their hospitalization, of whom 25 (27.4%) required dialysis. The median suPAR level was 5.61 ng/ml. AKI incidence rose with increasing suPAR tertiles, from a 6.0% incidence in patients with suPAR <4.60 ng/ml (first tertile) to a 45.8% incidence of AKI in patients with suPAR levels >6.86 ng/ml (third tertile). None of the patients with suPAR <4.60 ng/ml required dialysis during their hospitalization. In multivariable analysis, the highest suPAR tertile was associated with a 9.15-fold increase in the odds of AKI (95% confidence interval [95% CI], 3.64 to 22.93) and a 22.86-fold increase in the odds of requiring dialysis (95% CI, 2.77 to 188.75). The association was independent of inflammatory markers and persisted across subgroups.CONCLUSIONS: Admission suPAR levels in patients hospitalized for COVID-19 are predictive of in-hospital AKI and the need for dialysis. SuPAR may be a key component of the pathophysiology of AKI in COVID-19.
Published: 2020

35. Inflammation, Hyperglycemia, and Adverse Outcomes in Individuals With Diabetes Mellitus Hospitalized for COVID-19.

Author: Vasbinder, Alexi, Anderson, Elizabeth, Shadid, Husam, Berlin, Hanna, Pan, Michael, Azam, Tariq U., Khaleel, Ibrahim, Padalia, Kishan, Meloche, Chelsea, O'Hayer, Patrick, Michaud, Erinleigh, Catalan, Tonimarie, Feroze, Rafey, Blakely, Pennelope, Launius, Christopher, Huang, Yiyuan, Zhao, Lili, Ang, Lynn, Mikhael, Monica, and Mizokami-Stout, Kara
Subjects: HYPERGLYCEMIA, DIABETES, COVID-19, PLASMINOGEN activators, RENAL replacement therapy, INSULIN therapy
Abstract: Objective: Diabetes mellitus (DM) is a major risk factor for severe coronavirus disease 2019 (COVID-19) for reasons that are unclear.Research Design and Methods: We leveraged the International Study of Inflammation in COVID-19 (ISIC), a multicenter observational study of 2,044 patients hospitalized with COVID-19, to characterize the impact of DM on in-hospital outcomes and assess the contribution of inflammation and hyperglycemia to the risk attributed to DM. We measured biomarkers of inflammation collected at hospital admission and collected glucose levels and insulin data throughout hospitalization. The primary outcome was the composite of in-hospital death, need for mechanical ventilation, and need for renal replacement therapy.Results: Among participants (mean age 60 years, 58.2% males), those with DM (n = 686, 33.5%) had a significantly higher cumulative incidence of the primary outcome (37.8% vs. 28.6%) and higher levels of inflammatory biomarkers than those without DM. Among biomarkers, DM was only associated with higher soluble urokinase plasminogen activator receptor (suPAR) levels in multivariable analysis. Adjusting for suPAR levels abrogated the association between DM and the primary outcome (adjusted odds ratio 1.23 [95% CI 0.78, 1.37]). In mediation analysis, we estimated the proportion of the effect of DM on the primary outcome mediated by suPAR at 84.2%. Hyperglycemia and higher insulin doses were independent predictors of the primary outcome, with effect sizes unaffected by adjusting for suPAR levels.Conclusions: Our findings suggest that the association between DM and outcomes in COVID-19 is largely mediated by hyperinflammation as assessed by suPAR levels, while the impact of hyperglycemia is independent of inflammation. [ABSTRACT FROM AUTHOR]
Published: 2022
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36. In-hospital cardiac arrest in critically ill patients with covid-19: multicenter cohort study

Author: Hayek, Salim S, primary, Brenner, Samantha K, additional, Azam, Tariq U, additional, Shadid, Husam R, additional, Anderson, Elizabeth, additional, Berlin, Hanna, additional, Pan, Michael, additional, Meloche, Chelsea, additional, Feroz, Rafey, additional, O’Hayer, Patrick, additional, Kaakati, Rayan, additional, Bitar, Abbas, additional, Padalia, Kishan, additional, Perry, Daniel, additional, Blakely, Pennelope, additional, Gupta, Shruti, additional, Shaefi, Shahzad, additional, Srivastava, Anand, additional, Charytan, David M, additional, Bansal, Anip, additional, Mallappallil, Mary, additional, Melamed, Michal L, additional, Shehata, Alexandre M, additional, Sunderram, Jag, additional, Mathews, Kusum S, additional, Sutherland, Anne K, additional, Nallamothu, Brahmajee K, additional, and Leaf, David E, additional
Published: 2020
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37. ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance

Author: Orme, Jacob J., primary, Jazieh, Khalid A., additional, Xie, Tiancheng, additional, Harrington, Susan, additional, Liu, Xin, additional, Ball, Matthew, additional, Madden, Benjamin, additional, Charlesworth, M. Cristine, additional, Azam, Tariq U., additional, Lucien, Fabrice, additional, Wootla, Bharath, additional, Li, Yanli, additional, Villasboas, Jose Caetano, additional, Mansfield, Aaron S., additional, Dronca, Roxana S., additional, and Dong, Haidong, additional
Published: 2020
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38. Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and Outcomes in Patients Hospitalized for COVID-19.

Author: Pan, Michael, Vasbinder, Alexi, Anderson, Elizabeth, Catalan, Toniemarie, Shadid, Husam R., Berlin, Hanna, Padalia, Kishan, O'Hayer, Patrick, Meloche, Chelsea, Azam, Tariq U., Khaleel, Ibrahim, Michaud, Erinleigh, Blakely, Pennelope, Bitar, Abbas, Yiyuan Huang, Lili Zhao, Pop-Busui, Rodica, Loosen, Sven H., Chalkias, Athanasios, and Tacke, Frank
Published: 2021
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39. Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US

Author: Gupta, Shruti, Hayek, Salim S., Wang, Wei, Chan, Lili, Mathews, Kusum S., Melamed, Michal L., Brenner, Samantha K., Leonberg-Yoo, Amanda, Schenck, Edward J., Radbel, Jared, Reiser, Jochen, Bansal, Anip, Srivastava, Anand, Zhou, Yan, Sutherland, Anne, Green, Adam, Shehata, Alexandre M., Goyal, Nitender, Vijayan, Anitha, Velez, Juan Carlos Q., Shaefi, Shahzad, Parikh, Chirag R., Arunthamakun, Justin, Athavale, Ambarish M., Friedman, Allon N., Short, Samuel A. P., Kibbelaar, Zoe A., Abu Omar, Samah, Admon, Andrew J., Donnelly, John P., Gershengorn, Hayley B., Hernán, Miguel A., Semler, Matthew W., Leaf, David E., Walther, Carl P, Anumudu, Samaya J, Kopecky, Kathleen F, Milligan, Gregory P, McCullough, Peter A, Nguyen, Thuy-Duyen, Krajewski, Megan L, Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D, Waikar, Sushrut S, Hart, Peter, Ajiboye, Oyintayo, Itteera, Matthew, Rachoin, Jean-Sebastien, Schorr, Christa A, Shea, Lisa, Edmonston, Daniel L, Mosher, Christopher L, Karp, Aaron, Cohen, Zaza, Allusson, Valerie, Bambrick-Santoyo, Gabriela, Bhatti, Noor ul aain, Mehta, Bijal, Williams, Aquino, Walters, Patricia, Go, Rolando C, Rose, Keith M, Zhou, Amy M, Kim, Ethan C, Lisk, Rebecca, Coca, Steven G, Altman, Deena R, Saha, Aparna, Soh, Howard, Wen, Huei Hsun, Bose, Sonali, Leven, Emily A, Wang, Jing G, Mosoyan, Gohar, Nadkarni, Girish N, Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Garibaldi, Brian T, Corona-Villalobos, Celia P, Wen, Yumeng, Menez, Steven, Malik, Rubab F, Cervantes, Carmen Elena, Gautam, Samir C, Nguyen, H Byrant, Ahoubim, Afshin, Thomas, Leslie F, Sirganagari, Dheeraj Reddy, Guru, Pramod K, Bergl, Paul A, Rodriguez, Jesus, Shah, Jatan A, Gupta, Mrigank S, Kumar, Princy N, Lazarous, Deepa G, Kassaye, Seble G, Johns, Tanya S, Mocerino, Ryan, Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V, Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Raichoudhury, Ritesh, Cho, Soo Jung, Plataki, Maria, Alvarez-Mulett, Sergio L, Gomez-Escobar, Luis G, Pan, Di, Lee, Stefi, Kirshnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Ross, Daniel W, Leidner, Alexander S, Martinez, Carlos, Kruser, Jacqueline M, Wunderink, Richard G, Hodakowski, Alexander J, Price-Haywood, Eboni G, Matute-Trochez, Luis A, Hasty, Anne E, Mohamed, Muner MB, Avasare, Rupali S, Zonies, David, Baron, Rebecca M, Sise, Meghan E, Newman, Erik T, Pokharel, Kapil K, Sharma, Shreyak, Singh, Harkarandeep, Correa, Simon, Shaukat, Tanveer, Kamal, Omer, Yang, Heather, Boateng, Jeffery O, Lee, Meghan, Strohbehn, Ian A, Li, Jiahua, Muhsin, Saif A, Mandel, Ernest I, Mueller, Ariel L, Cairl, Nicholas S, Rowan, Chris, Madhai-Lovely, Farah, Peev, Vasil, Byun, John J, Vissing, Andrew, Kapania, Esha M, Post, Zoe, Patel, Nilam P, Hermes, Joy-Marie, Patrawalla, Amee, Finkel, Diana G, Danek, Barbara A, Arikapudi, Sowminya, Paer, Jeffery M, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T, Ahmed, Ayesha, Berim, Ilya, Hussain, Sabiha, Anand, Shuchi, Levitt, Joseph E, Garcia, Pablo, Boyle, Suzanne M, Song, Rui, Zhang, Jingjing, Sharshir, Mohd A, Rusnak, Vadym V, Podoll, Amber S, Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L, Rashidi, Arash, Hejal, Rana, Judd, Erik T, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E, Adams, Jason Y, Chang, Steven Y, Beutler, Rebecca M, Schulze, Carl E, Macedo, Etienne, Rhee, Harin, Liu, Kathleen D, Jotwani, Vasantha K, Koyner, Jay L, Shah, Chintan V, Jaikaransingh, Vishal, Toth-Manikowski, Stephanie M, Joo, Min J, Lash, James P, Neyra, Javier A, Chaaban, Nourhan, Iardino, Alfredo, Au, Elizabeth H, Sharma, Jill H, Sosa, Marie Anne, Taldone, Sabrina, Contreras, Gabriel, Zerda, David De La, Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U, Shadid, Husam, Pan, Michael, OHayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Padalia, Kishan J, Bitar, Abbas, Flythe, Jennifer E, Tugman, Matthew J, Brown, Brent R, Spiardi, Ryan C, Miano, Todd A, Roche, Meaghan S, Vasquez, Charles R, Bansal, Amar D, Ernecoff, Natalie C, Kovesdy, Csaba P, Molnar, Miklos Z, Azhar, Ambreen, Hedayati, Susan S, Nadamuni, Mridula V, Khan, Sadaf S, Willett, Duwayne L, Renaghan, Amanda D, Bhatraju, Pavan K, Malik, Bilal A, Joy, Christina Mariyam, Li, Tingting, Goldberg, Seth, Kao, Patricia F, Schumaker, Greg L, Faugno, Anthony J, Hsu, Caroline M, Tariq, Asma, Meyer, Leah, Weiner, Daniel E, Christov, Marta, Wilson, Francis P, Arora, Tanima, and Ugwuowo, Ugochukwu
Subjects: medicine.medical_specialty, business.industry, 010102 general mathematics, Organ dysfunction, Odds ratio, medicine.disease, 01 natural sciences, Intensive care unit, Comorbidity, law.invention, 03 medical and health sciences, 0302 clinical medicine, Interquartile range, law, Intensive care, Internal medicine, Internal Medicine, Medicine, 030212 general & internal medicine, 0101 mathematics, medicine.symptom, business, Body mass index, Cohort study
Abstract: Importance: The US is currently an epicenter of the coronavirus disease 2019 (COVID-19) pandemic, yet few national data are available on patient characteristics, treatment, and outcomes of critical illness from COVID-19. Objectives: To assess factors associated with death and to examine interhospital variation in treatment and outcomes for patients with COVID-19. Design, Setting, and Participants: This multicenter cohort study assessed 2215 adults with laboratory-confirmed COVID-19 who were admitted to intensive care units (ICUs) at 65 hospitals across the US from March 4 to April 4, 2020. Exposures: Patient-level data, including demographics, comorbidities, and organ dysfunction, and hospital characteristics, including number of ICU beds. Main Outcomes and Measures: The primary outcome was 28-day in-hospital mortality. Multilevel logistic regression was used to evaluate factors associated with death and to examine interhospital variation in treatment and outcomes. Results: A total of 2215 patients (mean [SD] age, 60.5 [14.5] years; 1436 [64.8%] male; 1738 [78.5%] with at least 1 chronic comorbidity) were included in the study. At 28 days after ICU admission, 784 patients (35.4%) had died, 824 (37.2%) were discharged, and 607 (27.4%) remained hospitalized. At the end of study follow-up (median, 16 days; interquartile range, 8-28 days), 875 patients (39.5%) had died, 1203 (54.3%) were discharged, and 137 (6.2%) remained hospitalized. Factors independently associated with death included older age (≥80 vs
Published: 2020

40. Abstract A210: Tumor-associated ADAM10 and ADAM17 produce soluble PD-L1 (sPD-L1, sB7-H1) and affect downstream tumor immunity – A resistance mechanism to PD-1 checkpoint blockade in melanoma

Author: Orme, Jacob J., primary, Jazieh, Khalid, additional, Harrington, Susan, additional, Ball, Matthew, additional, Azam, Tariq U., additional, Liu, Xin (Cindy), additional, Xie, Tiancheng, additional, Mansfield, Aaron, additional, Dronca, Roxana S., additional, and Dong, Haidong, additional
Published: 2019
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41. Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials

Author: Duma, Narjust, primary, Kothadia, Sejal M., additional, Azam, Tariq U., additional, Yadav, Siddhartha, additional, Paludo, Jonas, additional, Vera Aguilera, Jesus, additional, Gonzalez Velez, Miguel, additional, Halfdanarson, Thorvardur Ragnar, additional, Molina, Julian R., additional, Hubbard, Joleen M., additional, Go, Ronald S., additional, Mansfield, Aaron S., additional, and Adjei, Alex A., additional
Published: 2018
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42. Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials.

Author: Duma, Narjust, Kothadia, Sejal M., Azam, Tariq U., Yadav, Siddhartha, Paludo, Jonas, Vera Aguilera, Jesus, Gonzalez Velez, Miguel, Halfdanarson, Thorvardur Ragnar, Molina, Julian R., Hubbard, Joleen M., Go, Ronald S., Mansfield, Aaron S., and Adjei, Alex A.
Subjects: LIVER physiology, CENTRAL nervous system tumors, BREAST tumors, CANCER chemotherapy, CLINICAL trials, COLON tumors, HEPATITIS B, HEPATITIS C, HIV infections, LUNG tumors, METASTASIS, MULTIVARIATE analysis, RECTUM tumors, STATISTICS, VIRUS diseases, COMORBIDITY, LOGISTIC regression analysis, PATIENT selection, ODDS ratio, TUMOR treatment
Abstract: Background: Early phase clinical trials evaluate the safety and efficacy of new treatments. The exclusion/inclusion criteria in these trials are usually rigorous and may exclude many patients seen in clinical practice. Our objective was to study the comorbidities limiting the participation of patients with breast, colorectal, or lung cancer in clinical trials. Materials and Methods: We queried ClinicalTrials.gov on December 31, 2016. We reviewed the eligibility criteria of 1,103 trials. Logistic regression analyses were completed, and exclusion was studied as a binary variable. Results: Out of 1,103 trials, 70 trials (6%) excluded patients >75 years of age, and 45% made no reference to age. Eighty‐six percent of trials placed restrictions on patients with history of prior malignancies. Regarding central nervous system (CNS) metastasis, 416 trials (38%) excluded all patients with CNS metastasis, and 373 (34%) only allowed asymptomatic CNS metastasis. Regarding chronic viral infections, 347 trials (31%) excluded all patients with human immunodeficiency virus, and 228 trials (21%) excluded all patients with hepatitis B or C infection. On univariate analysis, chemotherapy trials were more likely to exclude patients with CNS metastasis and history of other malignancies than targeted therapy trials. Multivariate analysis demonstrated that industry‐sponsored trials had higher odds of excluding patients with compromised liver function. Conclusion: Many clinical trials excluded large segments of the population of patients with cancer. Frequent exclusion criteria included patients with CNS metastasis, history of prior malignancies, and chronic viral infections. The criteria for participation in some clinical trials may be overly restrictive and limit enrollment. Implications for Practice: The results of this study revealed that most early phase clinic trials contain strict exclusion criteria, potentially excluding the patients who may be more likely to represent the population treated in clinical settings, leaving patients susceptible to unintended harm from inappropriate generalization of trial results. Careful liberalization of the inclusion/exclusion criteria in clinical trials will allow investigators to understand the benefits and drawbacks of the experimental drug for a broader population, and possibly improve recruitment of patients with cancer into clinical trials. Although the number of clinical trials registered annually has increased, inclusion and exclusion criteria limit the number of patients eligible for trial participation. This study aimed to identify comorbidities and other exclusion criteria that have limited the recruitment of patients with breast, colorectal, and lung cancers into early phase clinical trials. [ABSTRACT FROM AUTHOR]
Published: 2019
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43. Relationship Between Preexisting Cardiovascular Disease and Death and Cardiovascular Outcomes in Critically Ill Patients With COVID-19.

Author: Vasbinder, Alexi, Meloche, Chelsea, Azam, Tariq U., Anderson, Elizabeth, Catalan, Tonimarie, Shadid, Husam, Berlin, Hanna, Pan, Michael, O'Hayer, Patrick, Padalia, Kishan, Blakely, Pennelope, Khaleel, Ibrahim, Michaud, Erinleigh, Huang, Yiyuan, Zhao, Lili, Pop-Busui, Rodica, Gupta, Shruti, Eagle, Kim, Leaf, David E., and Hayek, Salim S.
Abstract: Background: Preexisting cardiovascular disease (CVD) is perceived as a risk factor for poor outcomes in patients with COVID-19. We sought to determine whether CVD is associated with in-hospital death and cardiovascular events in critically ill patients with COVID-19.Methods: This study used data from a multicenter cohort of adults with laboratory-confirmed COVID-19 admitted to intensive care units at 68 centers across the United States from March 1 to July 1, 2020. The primary exposure was CVD, defined as preexisting coronary artery disease, congestive heart failure, or atrial fibrillation/flutter. Myocardial injury on intensive care unit admission defined as a troponin I or T level above the 99th percentile upper reference limit of normal was a secondary exposure. The primary outcome was 28-day in-hospital mortality. Secondary outcomes included cardiovascular events (cardiac arrest, new-onset arrhythmias, new-onset heart failure, myocarditis, pericarditis, or stroke) within 14 days.Results: Among 5133 patients (3231 male [62.9%]; mean age 61 years [SD, 15]), 1174 (22.9%) had preexisting CVD. A total of 1178 (34.6%) died, and 920 (17.9%) had a cardiovascular event. After adjusting for age, sex, race, body mass index, history of smoking, and comorbidities, preexisting CVD was associated with a 1.15 (95% CI, 0.98-1.34) higher odds of death. No independent association was observed between preexisting CVD and cardiovascular events. Myocardial injury on intensive care unit admission was associated with higher odds of death (adjusted odds ratio, 1.93 [95% CI, 1.61-2.31]) and cardiovascular events (adjusted odds ratio, 1.82 [95% CI, 1.47-2.24]), regardless of the presence of CVD.Conclusions: CVD risk factors, rather than CVD itself, were the major contributors to outcomes in critically ill patients with COVID-19. The occurrence of myocardial injury, regardless of CVD, and its association with outcomes suggests it is likely due to multiorgan injury related to acute inflammation rather than exacerbation of preexisting CVD.Registration: NCT04343898; https://clinicaltrials.gov/ct2/show/NCT04343898. [ABSTRACT FROM AUTHOR]
Published: 2022
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44. Gender Parity in Medical School Does Not Equal Gender Parity in Medical School Leadership.

Author: Azam, Tariq U. and Oxentenko, Amy S.
Subjects: *MEDICAL schools, *DEANS (Education), *DISCRIMINATION (Sociology), *EMPLOYEE recruitment, *LEADERSHIP, *MEMORY, *SEX distribution, *PSYCHOLOGY of women, *EDUCATIONAL attainment, *PARITY (Obstetrics)
Abstract: An introduction is presented in which the editor discusses the impact of gender parity in the leadership roles in medical schools.
Published: 2019
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45. Biomarkers of chronic inflammation and cognitive decline: A prospective observational study.

Author: Guduguntla BA, Vasbinder A, Anderson E, Azam TU, Blakely P, Webster NJ, Gonzalez R, Atonucci T, Heidebrink JL, Giordani B, Zahodne L, Hampstead BM, Ajrouch KJ, and Hayek SS
Abstract: We sought to determine whether the biomarkers of chronic inflammation predict cognitive decline in a prospective observational study. We measured baseline serum soluble urokinase plasminogen activator receptor (suPAR) and high sensitivity C-reactive protein (hs-CRP) levels in 282 participants of the University of Michigan Memory and Aging Project. Cognitive function was measured using the Montreal Cognitive Assessment (MoCA) and the Clinical Dementia Rating (CDR) scale for up to five time points. SuPAR and hs-CRP levels were not significantly higher in participants with mild cognitive impairment ( n = 97) or dementia ( n = 59), compared to those with normal cognitive function ( n = 126). Overall, 14% of participants experienced significant cognitive decline over the study period. The change in MoCA or CDR scores over time did not differ significantly according to baseline suPAR or hs-CRP levels. Chronic systemic inflammation, as measured by serum suPAR or hs-CRP levels, is unlikely to contribute significantly to cognitive decline., Competing Interests: SSH is a member of the scientific advisory board of Walden Biosciences. Other authors do not have a conflict of interest. Author disclosures are available in the supporting information., (© 2024 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)
Published: 2024
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46. Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI.

Author: Azam TU, Shadid HR, Blakely P, O'Hayer P, Berlin H, Pan M, Zhao P, Zhao L, Pennathur S, Pop-Busui R, Altintas I, Tingleff J, Stauning MA, Andersen O, Adami ME, Solomonidi N, Tsilika M, Tober-Lau P, Arnaoutoglou E, Keitel V, Tacke F, Chalkias A, Loosen SH, Giamarellos-Bourboulis EJ, Eugen-Olsen J, Reiser J, and Hayek SS
Subjects: Acute Kidney Injury blood, Acute Kidney Injury epidemiology, Adult, Aged, Aged, 80 and over, COVID-19, Female, Humans, Incidence, Male, Middle Aged, Pandemics, SARS-CoV-2, Acute Kidney Injury etiology, Betacoronavirus, Coronavirus Infections complications, Pneumonia, Viral complications, Receptors, Urokinase Plasminogen Activator blood
Abstract: Background: AKI commonly occurs in patients with coronavirus disease 2019 (COVID-19). Its pathogenesis is poorly understood. The urokinase receptor system is a key regulator of the intersection between inflammation, immunity, and coagulation, and soluble urokinase plasminogen activator receptor (suPAR) has been identified as an immunologic risk factor for AKI. Whether suPAR is associated with COVID-19-related AKI is unknown., Methods: In a multinational observational study of adult patients hospitalized for COVID-19, we measured suPAR levels in plasma samples from 352 adult patients that had been collected within 48 hours of admission. We examined the association between suPAR levels and incident in-hospital AKI., Results: Of the 352 patients (57.4% were male, 13.9% were black, and mean age was 61 years), 91 (25.9%) developed AKI during their hospitalization, of whom 25 (27.4%) required dialysis. The median suPAR level was 5.61 ng/ml. AKI incidence rose with increasing suPAR tertiles, from a 6.0% incidence in patients with suPAR <4.60 ng/ml (first tertile) to a 45.8% incidence of AKI in patients with suPAR levels >6.86 ng/ml (third tertile). None of the patients with suPAR <4.60 ng/ml required dialysis during their hospitalization. In multivariable analysis, the highest suPAR tertile was associated with a 9.15-fold increase in the odds of AKI (95% confidence interval [95% CI], 3.64 to 22.93) and a 22.86-fold increase in the odds of requiring dialysis (95% CI, 2.77 to 188.75). The association was independent of inflammatory markers and persisted across subgroups., Conclusions: Admission suPAR levels in patients hospitalized for COVID-19 are predictive of in-hospital AKI and the need for dialysis. SuPAR may be a key component of the pathophysiology of AKI in COVID-19., (Copyright © 2020 by the American Society of Nephrology.)
Published: 2020
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