23 results on '"Betzi, Stéphane"'
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2. ChemoDOTS: a web server to design chemistry-driven focused libraries
3. 4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
4. From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia
5. Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein–Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach
6. CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation
7. CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation
8. Discovery of small molecule inhibitors of the PTK7/β-catenin inter-action targeting the Wnt signaling pathway in colorectal cancer
9. Revisiting the molecular interactions between the tumor protein TCTP and the drugs sertraline/thioridazine.
10. In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
11. In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
12. Revisiting the Molecular Interactions between the Tumor Protein TCTP and the Drugs Sertraline/Thioridazine.
13. Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
14. Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach
15. Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
16. Author response: Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
17. Protein–Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery
18. Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins
19. 2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions
20. Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer
21. CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation
22. 4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
23. Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis.
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