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5. Corrigendum to “WCN24-1051 CLINICAL PROFILE, DIAGNOSIS, THERAPEUTIC INTERVENTION AND COMPLICATIONS IN RENAL BIOPSY IN CKD POPULATION – SINGLE CENTER 20 YEARS’ EXPERIENCE” [Kidney International Reports Volume 9, Issue 4, Supplement, April 2024, Page S86]

Author

Mohakuda, Souryasourabh, primary, Bhadauria, Dharmendra Singh, additional, Kaul, Anupma, additional, Prasad, Narayan, additional, Patel, Manas Ranjan, additional, Yachha, Monika, additional, Behera, Manas Ranjan, additional, and Kushwaha, Ravi Singh, additional

Published
2024
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15. Renal artery involvement is associated with increased morbidity but not mortality in Takayasu arteritis: a matched cohort study of 215 patients

Author

Thakare, Darpan R., primary, Mishra, Prabhaker, additional, Rathore, Upendra, additional, Singh, Kritika, additional, Dixit, Juhi, additional, Qamar, Tooba, additional, Behera, Manas Ranjan, additional, Jain, Neeraj, additional, Ora, Manish, additional, Bhadauria, Dharmendra Singh, additional, Gambhir, Sanjay, additional, Kumar, Sudeep, additional, Agarwal, Vikas, additional, and Misra, Durga Prasanna, additional

Published
2023
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16. Increased mortality rate in Takayasu arteritis is largely driven by cardiovascular disease: a cohort study

Author

Jagtap, Swapnil, primary, Mishra, Prabhaker, additional, Rathore, Upendra, additional, Thakare, Darpan R, additional, Singh, Kritika, additional, Dixit, Juhi, additional, Qamar, Tooba, additional, Behera, Manas Ranjan, additional, Jain, Neeraj, additional, Ora, Manish, additional, Bhadauria, Dharmendra Singh, additional, Gambhir, Sanjay, additional, Kumar, Sudeep, additional, Agarwal, Vikas, additional, and Misra, Durga Prasanna, additional

Published
2023
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22. Long-term outcomes in children on chronic continuous ambulatory peritoneal dialysis: a retrospective cohort study from a developing country

Author

Prasad, Narayan, Rangaswamy, Dharshan, Patel, Manas, Gulati, Sanjeev, Bhadauria, Dharmendra, Kaul, Anupama, and Gupta, Amit

Subjects
Continuous ambulatory peritoneal dialysis -- Usage -- Patient outcomes, Chronic kidney failure -- Diagnosis, Peritoneal dialysis -- Usage -- Patient outcomes, Pediatric research, Health
Abstract

Background Peritoneal dialysis (PD) is the preferred modality of dialysis among children with end-stage renal disease. Methods To study the incidence of technique failure and survival among children with end-stage renal disease on continuous ambulatory peritoneal dialysis (CAPD), we included children younger than 18 years of age who commenced and continued PD for more than 3 months as their primary form of dialysis between 1st January 2005 and 31st December 2016. Kaplan-Meier survival analysis was applied to analyze the CAPD outcomes. Results A total of 68 Tenckhoff (58 double cuffs, and ten single cuffs) catheters were inserted in 66 patients (mean age 12.3 ± 3.91 years) during the study period. Of the 66 children, 31 (47%) experienced 45 episodes of peritonitis. The total duration on CAPD was 107.58 years with a peritonitis rate of 0.42 episodes per year. Overall, the mean patient survival was 41 (95% confidence interval (CI) 29-54) months, with mean patient survival of 72% at 12 months, declining to 30% at 36 months and then remaining stable until the end of follow-up (106 months). The overall mean technique survival was 55 (95% CI 40-69) months, with mean technique survival of 69% at 12 months, declining to 44% at 36 months and then remaining stable until the end of follow-up (106 months). Conclusion CAPD is a viable option for end-stage renal disease in children from developing countries with a lack of access to automated PD and pediatric hemodialysis centers., Author(s): Narayan Prasad [sup.1] , Dharshan Rangaswamy [sup.2] , Manas Patel [sup.1] , Sanjeev Gulati [sup.3] , Dharmendra Bhadauria [sup.1] , Anupama Kaul [sup.1] , Amit Gupta [sup.1] Author Affiliations: [...]

Published
2019
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23. Antibody response to ChAdOx1 nCoV‐19 (Covishield®) vaccine in people on maintenance hemodialysis.

Author

Bhadauria, Dharmendra Singh, Tiwari, Prachi, Goel, Amit, Katiyar, Harshita, Kaul, Anupma, Mayank, Aggarwal, Amita, Verma, Alka, Khetan, Dhiraj, Yachha, Monika, Behera, Manas Ranjan, Yadav, Brijesh, Agarwal, Kartik, and Prasad, Narayan

Subjects
*ANTIBODY formation, *COVID-19, *RENAL replacement therapy, *VACCINES, *COVID-19 vaccines
Abstract

Introduction: People on renal replacement therapy (RRT) have a high risk of COVID‐19 infection and subsequent death. COVID‐19 vaccination is strongly recommended for those on RRT. Data are limited on the immune response of the ChAdOx1 nCoV‐19/AZD1222 (Covishield®) vaccine in patients on RRT. Methods: A prospective cohort of adult (age > 18 years), on RRT in the form of hemodialysis were included and received two intramuscular doses of Covishield®. A blood specimen of 5.0 mL was collected at two time points, within a few days before administering the first dose of the vaccine and at 4–16 weeks after the second dose. According to their prior COVID‐19 infection status, the participants were grouped as (i) prior symptomatic COVID‐19 infection, (ii) prior asymptomatic COVID‐19 infection, and (iii) no prior COVID‐19 infection. Results: A large proportion (81%) of participants had anti‐spike antibodies (ASAb) before vaccination, and a reasonable proportion (30%) also had neutralizing antibodies (NAb). The titer of ASAb was relatively low (207 U/mL) before vaccination. The ASAb titer (9405 [1635–25,000] U/mL) and percentage of NAb (96.4% [59.6–98.1%]) were markedly increased following the administration of two doses of the vaccine. The participants' prior COVID‐19 exposure status did not influence the rise in ASAb titer and NAb percentage. Further, administering two doses of the Covishield vaccine helps them achieve a high ASAb titer. Conclusion: Two doses of ChAdOx1 nCoV‐19/AZD1222 (Covishield®) vaccine, given 12 weeks apart, achieve a high titer of ASAb and a high percentage of NAb in people on hemodialysis. [ABSTRACT FROM AUTHOR]

Published
2023
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25. Paediatric-onset Takayasu's arteritis associates with worse survival than adult-onset Takayasu's arteritis. A matched retrospective cohort study

Author

Misra, Durga Prasanna, primary, Thakare, Darpan R., additional, Mishra, Prabhaker, additional, Rathore, Upendra, additional, Singh, Kritika, additional, Behera, Manas Ranjan, additional, Jain, Neeraj, additional, Ora, Manish, additional, Bhadauria, Dharmendra Singh, additional, Gambhir, Sanjay, additional, Kumar, Sudeep, additional, and Agarwal, Vikas, additional

Published
2023
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30. Durability of ChAdOx1 nCoV-19 (Covishield®) Vaccine Induced Antibody Response in Health Care Workers

Author

Verma, Alka, primary, Goel, Amit, additional, Katiyar, Harshita, additional, Tiwari, Prachi, additional, Mayank, Mayank, additional, Sana, Asari, additional, Khetan, Dheeraj, additional, Bhadauria, Dharmendra Singh, additional, Raja, Ajay, additional, Khokher, Neelam, additional, Shalimar, Shalimar, additional, Singh, Ratendra Kumar, additional, and Aggarwal, Amita, additional

Published
2022
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31. Impact of Geographic Location on Diagnosis and Initial Management of Takayasu Arteritis: A Tale of Two Cohorts from Italy and India

Author

Misra, Durga Prasanna, primary, Tomelleri, Alessandro, additional, Rathore, Upendra, additional, Benanti, Giovanni, additional, Singh, Kritika, additional, Behera, Manas Ranjan, additional, Jain, Neeraj, additional, Ora, Manish, additional, Bhadauria, Dharmendra Singh, additional, Gambhir, Sanjay, additional, Kumar, Sudeep, additional, Baldissera, Elena, additional, Agarwal, Vikas, additional, Campochiaro, Corrado, additional, and Dagna, Lorenzo, additional

Published
2022
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33. Comparison of Presentation and Prognosis of Takayasu Arteritis with or without Stroke or Transient Ischemic Attack—A Retrospective Cohort Study

Author

Misra, Durga Prasanna, primary, Rathore, Upendra, additional, Mishra, Prabhaker, additional, Singh, Kritika, additional, Thakare, Darpan R., additional, Behera, Manas Ranjan, additional, Jain, Neeraj, additional, Ora, Manish, additional, Bhadauria, Dharmendra Singh, additional, Gambhir, Sanjay, additional, Kumar, Sudeep, additional, and Agarwal, Vikas, additional

Published
2022
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34. Comparing Estimated and Measured Glomerular Filtration Rate in Children with Posterior Urethral Valve.

Author

Ora, Manish, Kalimuthu, Lokeshwaran Madurai, Mishra, Prabhakar, Nazar, Aftab Hasan, Bhadauria, Dharmendra S., Barai, Sukanta, and Gambhir, Sanjay

Subjects
GLOMERULAR filtration rate, IN vitro studies, CHRONIC kidney failure, URETHRA, KIDNEY function tests, URETHRAL obstruction, RETROSPECTIVE studies, COMPARATIVE studies, DESCRIPTIVE statistics, CREATININE, DISEASE complications, CHILDREN
Abstract

Background: Posterior urethral valve (PUV) is obstructive uropathy that may lead to chronic kidney disease (CKD) and end-stage renal disease (ESRD) in children. Glomerular filtration rate (GFR) measurement remains the gold standard for renal function measurement. However, due to its less availability and cumbersome, it is not commonly used, and GFR is estimated utilizing various endogenous filtration markers. Objective: This study includes pediatric patients with PUV. We aimed to compare the measured GFR (mGFR) with various creatinine-based estimated GFR methods (eGFR). Materials and Methods: A single-center retrospective study included 62 treated cases of PUV, postvalve fulguration. The mGFR measured by 99mTc-diethylenetriaminepentaacetate in vitro method and compared with eight eGFR (Schwartz, Cockcroft-Gault [CG], Counahan-Barratt [CB], CKD Epidemiology Collaboration [CKD-EPI], full-age spectrum [FAS] age, FAS height (FAS Ht), Schwartz-Lyon [SL], and Ht independent). Patients were subdivided into different CKD grades and compared with various eGFR. Discussion: PUV is a common cause of CKD in children and needs special consideration as there is growth retardation associated with it. It decreases creatinine production and thus fallacies in eGFR measurement. There is a requisite to identify and closely monitor the subset of patients with baseline decreased renal function and therefore at risk of developing ESRD. Results: A total of 62 patients were included. Mean age and serum creatinine levels were 8.02 ± 5.53 years and 1.15 ± 0.95 mg/dl (range: 0.4-4.5), respectively. The mean mGFR was 61.6 ± 31.80 mL/min/1.73 m² and a positive variable correlation was 0.46-0.77 between mGFR and eGFR. Based on mGFR, there were 14 (22.6%), 21 (33.8%), 13 (20.9%), 9 (14.5%), and 5 (8.1%) patients in Grades I-V, respectively. The correct classification of the CKD grades was noted in 25 (40.3%), 16 (25.8%), 32 (51.6%), 16 (25.8%), 25 (40.3%), 27 (43.5%), 26 (41.9%), and 28 (45.2%) patients by Schwartz, CG, CB, CKD-EPI, FAS age, FAS Ht, SL, and Ht-independent equation. The eGFR overestimates GFR at the lower level and underestimates at higher levels. Conclusion: Our results confirm the considerable limitations of various creatinine-based clearance methods for estimating actual GFR. The creatinine clearance-based eGFR should not replace the measurement of the GFR. An initial measure of the mGFR followed by serial follow-up with the eGFR equation may be done. The most accurate eGFR equations are CB for Grade II, SL or Ht independent for Grade III, FAS age for Grade IV, and SL for Grade V CKD. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Association of Human Leucocyte Antigen Polymorphism with Coronavirus Disease 19 in Renal Transplant Recipients

Author

Prasad, Narayan, primary, Yadav, Brijesh, additional, Prakash, Swayam, additional, Yadav, Deependra, additional, Singh, Ankita, additional, Gautam, Sonam, additional, Bhadauria, Dharmendra, additional, Kaul, Anupama, additional, Patel, Manas Ranjan, additional, Behera, Manas Ranjan, additional, Kushwaha, Ravi Shankar, additional, and Yachha, Monika, additional

Published
2022
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36. Antibody Response to ChAdOx1 nCoV-19 (AZD1222) Vaccine in Kidney Transplant Recipients

Author

Bhadauria, Dharmendra S., primary, Katiyar, Harshita, additional, Goel, Amit, additional, Tiwari, Prachi, additional, Kishore, Ravi V. Krishna, additional, Aggarwal, Amita, additional, Verma, Alka, additional, Khetan, Dheeraj, additional, Kaul, Anupma, additional, Yachha, Monika, additional, Behera, Manas Ranjan, additional, Yadav, Brijesh, additional, and Prasad, Narayan, additional

Published
2022
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40. Seroconversion Rate After SARS-CoV-2 Infection and Two Doses of Either ChAdOx1-nCOV COVISHIELD™ or BBV-152 COVAXIN™ Vaccination in Renal Allograft Recipients: An Experience of Two Public and Private Tertiary Care Center

Author

Prasad, Narayan, primary, Bansal, Shyam Bihari, additional, Yadav, Brijesh, additional, Manhas, Neha, additional, Yadav, Deependra, additional, Gautam, Sonam, additional, Kushwaha, Ravishankar, additional, Singh, Ankita, additional, Bhadauria, Dharmendra, additional, Yachha, Monika, additional, Behera, Manas Ranjan, additional, and Kaul, Anupama, additional

Published
2022
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47. Humoral Immune Response of SARS-CoV-2 Infection and Anti-SARS-CoV-2 Vaccination in Renal Transplant Recipients

Author

Prasad, Narayan, primary, Yadav, Brijesh, additional, Singh, Mantabya, additional, Gautam, Sonam, additional, Bhadauria, Dharmendra, additional, Patel, Manas, additional, Kushwaha, Ravi, additional, Yadav, Deependra, additional, Singh, Ankita, additional, Yachha, Monika, additional, Behera, Manas, additional, and Kaul, Anupama, additional

Published
2022
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48. Novel Th17 Lymphocyte Populations, Th17.1 and PD1+Th17, are Increased in Takayasu Arteritis, and Both Th17 and Th17.1 Sub-Populations Associate with Active Disease

Author

Singh, Kritika, primary, Rathore, Upendra, additional, Rai, Mohit Kumar, additional, Behera, Manas Ranjan, additional, Jain, Neeraj, additional, Ora, Manish, additional, Bhadauria, Dharmendra, additional, Sharma, Supriya, additional, Pande, Gaurav, additional, Gambhir, Sanjay, additional, Nath, Alok, additional, Kumar, Sudeep, additional, Sharma, Aman, additional, Agarwal, Vikas, additional, and Misra, Durga Prasanna, additional

Published
2022
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