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6. T.07.10 PERFORMANCE OF A MULTI-COMPOUNDS NUTRACEUTICAL FORMULATION IN PATIENTS WITH SYMPTOMATIC UNCOMPLICATED DIVERTICULAR DISEASE

Author

Gravina, A.G., primary, Brandimarte, G., additional, Frajese, G.V., additional, Bargiggia, S., additional, Castellani, D., additional, Cocco, A., additional, Colucci, R., additional, Evangelista, E., additional, Napoletano, D., additional, Nardi, E., additional, Maisto, T., additional, Morabito, A., additional, Pianese, G., additional, Romano, A., additional, Sacco, R., additional, Sinnona, N., additional, Sediari, L., additional, Tifi, L., additional, Davino, A., additional, Elisei, W., additional, and Tursi, A., additional

Published
2022
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8. Predictive value of the “DICA” classification on the outcome of diverticular disease of the colon: an international study: 3.14

Author

Tursi, A., Brandimarte, G., Di Mario, F., Annunziata, M. L., Bafutto, M., Bianco, M. A., Colucci, R., Conigliaro, R., Danese, S., De Bastiani, R., Elisei, W., Escalante, R., Faggiani, R., Ferrini, L., Forti, G., Latella, G., Graziani, M. G., Oliveira, E., Papa, A., Penna, A., Søreide, K., Spadaccini, A., Usai, P., Zampaletta, C., Cassieri, C., Desserud, K. F., Fiorella, S., Landi, R., Goni, E., Lai, M. A., Pigò, F., Scarpignato, C., Picchio, M., Scaccianoce, G., and Portincasa, P.

Published
2016

9. The DICA Endoscopic Classification for Diverticular Disease of the Colon Shows a Significant Interobserver Agreement among Community Endoscopists: an International Study

Author

Tursi A., Brandimarte G., Di Mario F., Lanas A., Scarpignato C., Bafutto M., Barbara G., Bassotti G., Binda G. A., Biondi A., Biondo S., Cassieri C., Crucitti A., Dumitrascu D. L., Elisei W., Escalante R., Herszenyi L., Kruis W., Kupcinskas J., Lahat A., Lecca P. G., Maconi G., Malfertheiner P., Mazzarri A., Mearin F., Milosavljevic T., Nardone G., de Oliveira E. C., Papa A., Papagrigoriadis S., Pera M., Persiani R., Picchio M., Regula J., Stimac D., Stollman N., Strate L. L., Walker M. M. D., Allegretta L., Altavilla N., Amaro P., Annunziata M. L., Barberio F., Basile G., Bedogni G., Belfiori V., Benvenuti S., Bertolami C., Bisello M., El Dammak M. B., Bozzi R., Buono M., Cambie G., Capezzuto E., Casamassima C., Chavoushian A., Ciofani R., Citarella C., Compare D., Cotruta B., D'amico F., Dulk M. D., Dyrda B. E., Festa V., Gallina S., Grasso R., Hanzel J., Taieb J. M., Lai M. A., Latella G., Lisi D., Lodi L., Marangi S., Mardegan A., Marlicz W., Maurano A., Milazzo G., Militaru V., Miraglia S., Monica F., Moskalev A., Natale A., Nicolas C., Pancetti A., Penna A., Pepe A. S., Pisano M., Pontone S., Prati M., Prisco A., Rando L., Hernandez E. R., Rosati O., Rossi G., Passoni G. R., Papa V., Nesme N. S., Schiffino L., Schillaci D., Selvaggi G., Taborchi F., Tornar A., Trebuna F., Triggiani C., Testai F. V., Vassallo R., Violi A., Tursi, A., Brandimarte, G., Di Mario, F., Lanas, A., Scarpignato, C., Bafutto, M., Barbara, G., Bassotti, G., Binda, G. A., Biondi, A., Biondo, S., Cassieri, C., Crucitti, A., Dumitrascu, D. L., Elisei, W., Escalante, R., Herszenyi, L., Kruis, W., Kupcinskas, J., Lahat, A., Lecca, P. G., Maconi, G., Malfertheiner, P., Mazzarri, A., Mearin, F., Milosavljevic, T., Nardone, G., de Oliveira, E. C., Papa, A., Papagrigoriadis, S., Pera, M., Persiani, R., Picchio, M., Regula, J., Stimac, D., Stollman, N., Strate, L. L., Walker, M. M. D., Allegretta, L., Altavilla, N., Amaro, P., Annunziata, M. L., Barberio, F., Basile, G., Bedogni, G., Belfiori, V., Benvenuti, S., Bertolami, C., Bisello, M., El Dammak, M. B., Bozzi, R., Buono, M., Cambie, G., Capezzuto, E., Casamassima, C., Chavoushian, A., Ciofani, R., Citarella, C., Compare, D., Cotruta, B., D'Amico, F., Dulk, M. D., Dyrda, B. E., Festa, V., Gallina, S., Grasso, R., Hanzel, J., Taieb, J. M., Lai, M. A., Latella, G., Lisi, D., Lodi, L., Marangi, S., Mardegan, A., Marlicz, W., Maurano, A., Milazzo, G., Militaru, V., Miraglia, S., Monica, F., Moskalev, A., Natale, A., Nicolas, C., Pancetti, A., Penna, A., Pepe, A. S., Pisano, M., Pontone, S., Prati, M., Prisco, A., Rando, L., Hernandez, E. R., Rosati, O., Rossi, G., Passoni, G. R., Papa, V., Nesme, N. S., Schiffino, L., Schillaci, D., Selvaggi, G., Taborchi, F., Tornar, A., Trebuna, F., Triggiani, C., Testai, F. V., Vassallo, R., Violi, A., Tursi A., Brandimarte G., Di Mario F., Lanas A., Scarpignato C., Bafutto M., Barbara G., Bassotti G., Binda G.A., Biondi A., Biondo S., Cassieri C., Crucitti A., Dumitrascu D.L., Elisei W., Escalante R., Herszenyi L., Kruis W., Kupcinskas J., Lahat A., Lecca P.G., Maconi G., Malfertheiner P., Mazzari A., Mearin F., Milosavljevic T., Nardone G., Chavez De Oliveira E., Papa A., Papagrigoriadis S., Pera M., Persiani R., Picchio M., Regula J., Stimac D., Stollman N., Strate L.L., and Walker M.M.

Subjects
BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences, Diverticular Disease, Endoscopic classification, Video Recording, Colonoscopy, Gastroenterology, Severity of Illness Index, endoscopic classification, Diverticulum, classification, complications, Diverticular diseases, Endoscopy, methods, Colonic Diseases, 0302 clinical medicine, Community Health Services, Community Health Service, Observer Variation, 0303 health sciences, medicine.diagnostic_test, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti, agreement − colonoscopy − community setting − diverticular disease of the colon− endoscopic classification, 3. Good health, Diverticulosis, Malalties del còlon, Diverticular disease of the colon, Diverticular disease, 616.344-007.64 [udc], Community setting, 030211 gastroenterology & hepatology, Human, medicine.medical_specialty, Scoring system, Colonic Disease, Settore MED/12 - GASTROENTEROLOGIA, Reproducibility of Result, agreement, colonoscopy, community setting, diverticular disease of the colon, Agreement, 03 medical and health sciences, Internal medicine, Severity of illness, medicine, Diverticulosis, Colonic, Humans, Colonic diseases, 030304 developmental biology, Diverticular Diseases, business.industry, Colonoscòpia, Reproducibility of Results, medicine.disease, Inter-rater reliability, business, Kappa
Abstract

Background and Aims: The Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification of diverticulosis and diverticular disease (DD) is currently available. It scores severity of the disease as DICA 1, DICA 2 and DICA 3. Our aim was to assess the agreement on this classification in an international endoscopists community setting. Methods: A total of 96 doctors (82.9% endoscopists) independently scored a set of DD endoscopic videos. The percentages of overall agreement on DICA score and a free-marginal multirater kappa (κ) coefficient were reported as statistical measures of interrater agreement. Results: Overall agreement in using DICA was 91.8% with a free-marginal kappa of 88% (95% CI 80-95). The overall agreement levels were: DICA 1, 85.2%; DICA 2, 96.5%; DICA 3, 99.5%. The free marginal κ was: DICA 1 = 0.753, DICA 2 = 0.958, DICA 3 = 0.919. The agreement about the main endoscopic items was 83.4% (k 67%) for diverticular extension, 62.6% (k 65%) for number of diverticula for each district, 86.8% (k 82%) for presence of inflammation, and 98.5 (k 98%) for presence of complications. Conclusions: The overall interrater agreement in this study ranges from good to very good. DICA score is a simple and reproducible endoscopic scoring system for diverticulosis and DD.

Published
2019

12. Predictive value of the ‘DICA’ classification on the outcome of diverticular disease of the colon: 2.14

Author

Tursi, A., Brandimarte, G., Di Mario, F., Annunziata, M. L., Bianco, M. A., Conigliaro, R., Elisei, W., Faggiani, R., Forti, G., Lecca, P. G., Penna, A., Spadaccini, A., Zampaletta, C., Colucci, R., De Bastiani, R., Di Cesare, L., Di Fonzo, M., Goni, E., Ferrini, L., Graziani, M. G., Latella, G., Pigò, F., Rotondano, G., Schiaccianoce, G., Picchio, M., Scarpignato, C., and Portincasa, P.

Published
2015

13. COVID-19 and the Global Impact on Colorectal Practice and Surgery

Author

Nunoo-Mensah, J. W., Rizk, M., Caushaj, P. F., Giordano, P., Fortunato, R., Dulskas, A., Bugra, D., da Costa Pereira, J. M., Escalante, R., Koda, K., Samalavicius, N. E., Maeda, K., Chun, H. -K., Elsayed, A., Ayantunde, A., Zaman, A., Adam, A., Mckinley, A., Marsillac, A., Shamardal, A., Jamiri, A. -R., Khushal, A., Allison, A., Isik, A., Erkan, A., Haq, A., Mehraj, A., Krasniqi, A., Unal, A., Cosman, B., Griffiths, B., Nara, B., Foo, C., Lapa, C., Varela, C., Dwivedi, D. K., Simcikas, D., Mladenovikj, D., Yazyi, F., Elias-Rabelo, F., Mcnicol, F., Dedemadi, G., Dimopoulou, G., Binda, G., Brandimarte, G., Brisinda, Giuseppe, Parker, G., Khawaja, H., Geogloman, H., Gallagher, H., Gecim, I., Pravosudov, I., Froehner, I., Dajti, I., Abdelmoneim, I., Lee, J., Mccormick, J., Tuech, J. -J., Rodrigues, J., Robinson, J., de-Leon-Rendon, J., Reina, J., Leite, J., De Silva, K., Cross, K., Takahashi, K., Kannappa, L., Toquero, L., Brochado, M., Islam, R., Tanal, M., Rubbini, M., Slavchev, M., Saeed, M., Khalil, M., Iqbal, N., Sah, N., Oluwajobi, O., Bulut, O., De Nardi, P., Junior, P. C., Haray, P., Makhoul, R., Fonseca, R., Talbot, R., Martins, R., Benli, S., Uribe, S., Liberman, S., Martinez, S., Tayar, S., Tsujinaka, S., Ng, S., Neagu, S., Sood, S., Saleem, T., Colak, T., El Zalabany, T., Khn, U., Stoyanov, V., Cirocco, W., Kiraitu, W., Delgadillo, X., Nakamoto, Y., Hamahata, Y., Kvedaras, V., Huq, Z., Khadija, Z., Brisinda G. (ORCID:0000-0001-8820-9471), Nunoo-Mensah, J. W., Rizk, M., Caushaj, P. F., Giordano, P., Fortunato, R., Dulskas, A., Bugra, D., da Costa Pereira, J. M., Escalante, R., Koda, K., Samalavicius, N. E., Maeda, K., Chun, H. -K., Elsayed, A., Ayantunde, A., Zaman, A., Adam, A., Mckinley, A., Marsillac, A., Shamardal, A., Jamiri, A. -R., Khushal, A., Allison, A., Isik, A., Erkan, A., Haq, A., Mehraj, A., Krasniqi, A., Unal, A., Cosman, B., Griffiths, B., Nara, B., Foo, C., Lapa, C., Varela, C., Dwivedi, D. K., Simcikas, D., Mladenovikj, D., Yazyi, F., Elias-Rabelo, F., Mcnicol, F., Dedemadi, G., Dimopoulou, G., Binda, G., Brandimarte, G., Brisinda, Giuseppe, Parker, G., Khawaja, H., Geogloman, H., Gallagher, H., Gecim, I., Pravosudov, I., Froehner, I., Dajti, I., Abdelmoneim, I., Lee, J., Mccormick, J., Tuech, J. -J., Rodrigues, J., Robinson, J., de-Leon-Rendon, J., Reina, J., Leite, J., De Silva, K., Cross, K., Takahashi, K., Kannappa, L., Toquero, L., Brochado, M., Islam, R., Tanal, M., Rubbini, M., Slavchev, M., Saeed, M., Khalil, M., Iqbal, N., Sah, N., Oluwajobi, O., Bulut, O., De Nardi, P., Junior, P. C., Haray, P., Makhoul, R., Fonseca, R., Talbot, R., Martins, R., Benli, S., Uribe, S., Liberman, S., Martinez, S., Tayar, S., Tsujinaka, S., Ng, S., Neagu, S., Sood, S., Saleem, T., Colak, T., El Zalabany, T., Khn, U., Stoyanov, V., Cirocco, W., Kiraitu, W., Delgadillo, X., Nakamoto, Y., Hamahata, Y., Kvedaras, V., Huq, Z., Khadija, Z., and Brisinda G. (ORCID:0000-0001-8820-9471)

Abstract

Background: The novel severe acute respiratory syndrome coronavirus 2 virus that emerged in December 2019 causing coronavirus disease 2019 (COVID-19) has led to the sudden national reorganization of health care systems and changes in the delivery of health care globally. The purpose of our study was to use a survey to assess the global effects of COVID-19 on colorectal practice and surgery. Materials and Methods: A panel of International Society of University Colon and Rectal Surgeons (ISUCRS) selected 22 questions, which were included in the questionnaire. The questionnaire was distributed electronically to ISUCRS fellows and other surgeons included in the ISUCRS database and was advertised on social media sites. The questionnaire remained open from April 16 to 28, 2020. Results: A total of 287 surgeons completed the survey. Of the 287 respondents, 90% were colorectal specialists or general surgeons with an interest in colorectal disease. COVID-19 had affected the practice of 96% of the surgeons, and 52% were now using telemedicine. Also, 66% reported that elective colorectal cancer surgery could proceed but with perioperative precautions. Of the 287 respondents, 19.5% reported that the use of personal protective equipment was the most important perioperative precaution. However, personal protective equipment was only provided by 9.1% of hospitals. In addition, 64% of surgeons were offering minimally invasive surgery. However, 44% reported that enough information was not available regarding the safety of the loss of intra-abdominal carbon dioxide gas during the COVID-19 pandemic. Finally, 61% of the surgeons were prepared to defer elective colorectal cancer surgery, with 29% willing to defer for ≤ 8 weeks. Conclusion: The results from our survey have demonstrated that, globally, COVID-19 has affected the ability of colorectal surgeons to offer care to their patients. We have also discussed suggestions for various practical adaptation strategies for use during the r

Published
2020

14. T01.01.14 THE ROLE OF A NON-INVASIVE TEST IN THE MANAGEMENT OF UPPER-GI DISEASES: COMPARISON BETWEEN SEROLOGY AND ENDOSCOPIC FINDINGS IN A SAMPLE OF 3,795 PATIENTS

Author

Barchi, A., primary, Franceschi, M., additional, Russo, M., additional, Miraglia, C., additional, Crafa, P., additional, Franzoni, L., additional, Ferronato, A., additional, Rodriguez-Castro, K., additional, Baldassarre, G., additional, Panozzo, M.P., additional, Antico, A., additional, Rugge, M., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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15. OC.08.3 THE “DICA” ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE OF THE COLON SHOWS A SIGNIFICANT INTEROBSERVER AGREEMENT AMONG COMMUNITY ENDOSCOPISTS: AN INTERNATIONAL STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Lanas, A., additional, Scarpignato, C., additional, Bafutto, M., additional, Barbara, G., additional, Bassotti, G., additional, Binda, G.A., additional, Biondi, A., additional, Biondo, S., additional, Cambiè, G., additional, Cassieri, C., additional, Crucitti, A., additional, Dumitrascu, D., additional, Elisei, W., additional, Escalante, R., additional, Herszènyi, L., additional, Kruis, W., additional, Kupcinskas, J., additional, Lahat, A., additional, Lecca, P.G., additional, Maconi, G., additional, Malfertheiner, P., additional, Mazzari, A., additional, Mearìn, F., additional, Milosavljevic, T., additional, Nardone, G., additional, Chavez De Oliveira, E., additional, Papa, A., additional, Papagrigoriadis, S., additional, Pera, M., additional, Persiani, R., additional, Picchio, M., additional, Regula, J., additional, Štimac, D., additional, Stollman, N., additional, Strate, L., additional, Violi, A., additional, and Walker, M., additional

Published
2020
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16. T04.01.12 USEFULNESS OF FECAL CALPROTECTIN IN PRIMARY CARE SETTING: AN EXPERIENCE IN NORTH – EAST ITALY POPULATION

Author

Moccia, F., primary, Ferronato, A., additional, Barchi, A., additional, Miraglia, C., additional, Russo, M., additional, Franceschi, M., additional, Rodriguez-Castro, K., additional, Baldassarre, G., additional, Franzoni, L., additional, Crafa, P., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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19. T01.02.17 CLINICAL USEFULNESS OF SECOND-GENERATION BARRIER DRUGS IN GERD PATIENTS WITH ATYPICAL SYMPTOMS: A-6-MONTHS PROSPECTIVE STUDY

Author

Barchi, A., primary, Russo, M., additional, Miraglia, C., additional, Franzoni, L., additional, Crafa, P., additional, Franceschi, M., additional, Baldassarre, G., additional, Rodriguez-Castro, K., additional, Tursi, A., additional, Brandimarte, G., additional, Savarino, E., additional, De Bortoli, N., additional, and Di Mario, F., additional

Published
2020
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20. T01.02.23 ROLE OF ENVIRONMENTAL FACTORS ON THE OUTCOME OF GASTROESOPHAGEAL REFLUX DISEASE: 6 MONTHS PROSPECTIVE STUDY

Author

Russo, M., primary, Barchi, A., additional, Miraglia, C., additional, Franzoni, L., additional, Crafa, P., additional, Franceschi, M., additional, Baldassarre, G., additional, Rodriguez-Castro, K., additional, Tursi, A., additional, Brandimarte, G., additional, Savarino, E., additional, De Bortoli, N., additional, and Di Mario, F., additional

Published
2020
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22. OC.08.6 USEFULNESS OF FECAL CALPROTECTIN IN PRIMARY CARE: NON-INVASIVE APPROACH FOR THE FRAMING OF INTESTINAL DISEASES

Author

Moccia, F., primary, Ferronato, A., additional, Franceschi, M., additional, Baldassarre, G., additional, Panozzo, M.P., additional, Antico, A., additional, Barchi, A., additional, Russo, M., additional, Miraglia, C., additional, Franzoni, L., additional, Crafa, P., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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24. T01.01.16 CORRELATION BETWEEN SERUM GASTRIC BIOMARKERS AND HISTOLOGICAL PICTURES OF H. PYLORI INFECTION AND ATROPHIC GASTRITIS: A POPULATION STUDY ON 1,122 PATIENTS

Author

Barchi, A., primary, Franceschi, M., additional, Russo, M., additional, Miraglia, C., additional, Crafa, P., additional, Franzoni, L., additional, Ferronato, A., additional, Rodriguez-Castro, K., additional, Baldassarre, G., additional, Panozzo, M.P., additional, Antico, A., additional, Rugge, M., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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29. Course of the diverticular disease: What is changing?

Author

Milasavljevic, T., Brandimarte, G., Stollman, N., Barbara, G., Lahat, A., Scarpignato, C., Lanas, A., Papa, Valerio, Tursi, A., Nardone, G., Papa V. (ORCID:0000-0002-3709-8924), Milasavljevic, T., Brandimarte, G., Stollman, N., Barbara, G., Lahat, A., Scarpignato, C., Lanas, A., Papa, Valerio, Tursi, A., Nardone, G., and Papa V. (ORCID:0000-0002-3709-8924)

Abstract

In this session several critical issues in diverticular disease were considered, including “It is symptomatic diverticular disease or irritable bowel syndrome?”, “What do determine evolution to diverticulitis, bowel habits alteration or inflammation?”, and “Prevention of acute diverticulitis: Is it at all possible?”. The first part compared symptoms and laboratory findings between symptomatic uncomplicated diverticular disease (SUDD) and irritable bowel syndrome (IBS). Although both diseases share same symptoms, and although IBS can occur in patients having diverticulosis, SUDD and IBS can be distinguished using a combination of symptoms and laboratory tools. The second part of this session debated what are the most important risk factors for the evolution towards acute diverticulitis (AD). Current data seem to exclude a significant role of bowel habits alteration, while inflammation seems to have a stronger role, especially in causing acute diverticulitis recurrence. The third part analyzed the prevention of acute diverticulitis. In primary prevention mesalazine seems to be useful, while no definite conclusion can be drawn about the use of fiber and rifaximin. For secondary prevention, no drugs can be currently advised. At the same time, surgery should be advised on case-by-case basis.

Published
2019

30. International consensus on diverticulosis and diverticular disease. Statements from the 3rd international symposium on diverticular disease

Author

Tursi, A., Brandimarte, G., Di Mario, F., Lanas, A., Scarpignato, C., Bafutto, M., Barbara, G., Bassotti, G., Binda, G. A., Biondi, Alberto, Biondo, S., Cambie, G., Cassieri, C., Crucitti, Antonio, Dumitrascu, D. L., Elisei, W., Escalante, R., Herszenyi, L., Kruis, W., Kupcinskas, J., Lahat, A., Lecca, P. G., Maconi, G., Malfertheiner, P., Mazzari, A., Mearin, F., Milosavljevic, T., Nardone, G., de Oliveira, E. C., Papa, Alfredo, Papagrigoriadis, S., Pera, M., Persiani, Roberto, Picchio, M., Regula, J., Stimac, D., Stollman, N., Strate, L. L., Violi, A., Walker, M. M. D., Biondi A. (ORCID:0000-0002-2470-7858), Crucitti A. (ORCID:0000-0003-3496-4185), Persiani R. (ORCID:0000-0002-1537-5097), Tursi, A., Brandimarte, G., Di Mario, F., Lanas, A., Scarpignato, C., Bafutto, M., Barbara, G., Bassotti, G., Binda, G. A., Biondi, Alberto, Biondo, S., Cambie, G., Cassieri, C., Crucitti, Antonio, Dumitrascu, D. L., Elisei, W., Escalante, R., Herszenyi, L., Kruis, W., Kupcinskas, J., Lahat, A., Lecca, P. G., Maconi, G., Malfertheiner, P., Mazzari, A., Mearin, F., Milosavljevic, T., Nardone, G., de Oliveira, E. C., Papa, Alfredo, Papagrigoriadis, S., Pera, M., Persiani, Roberto, Picchio, M., Regula, J., Stimac, D., Stollman, N., Strate, L. L., Violi, A., Walker, M. M. D., Biondi A. (ORCID:0000-0002-2470-7858), Crucitti A. (ORCID:0000-0003-3496-4185), and Persiani R. (ORCID:0000-0002-1537-5097)

Abstract

The statements produced by the Chairmen and Speakers of the 3rd International Symposium on Diverticular Disease, held in Madrid on April 11th-13th 2019, are reported. Topics such as current and evolving concepts on the pathogenesis, the course of the disease, the news in diagnosing, hot topics in medical and surgical treatments, and finally, critical issues on the disease were reviewed by the Chairmen who proposed 39 statements graded according to level of evidence and strength of recommendation. Each topic was explored focusing on the more relevant clinical questions. The vote was conducted on a 6-point scale and consensus was defined a priori as 67% agreement of the participants. The voting group consisted of 124 physicians from 18 countries, and agreement with all statements was provided. Comments were added explaining some controversial areas.

Published
2019

32. P.02.12 PREDICTIVE VALUE OF THE “DICA” ENDOSCOPIC CLASSIFICATION ON THE OUTCOME OF DIVERTICULAR DISEASE OF THE COLON: A 1-YEAR ANALYSIS FROM THE INTERNATIONAL, MULTICENTER, PROSPECTIVE STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Elisei, W., additional, Picchio, M., additional, Allegretta, L., additional, Annunziata, M.L., additional, Astegiano, M., additional, Bafutto, M., additional, Baldi, F., additional, Bassotti, G., additional, Bianco, M.A., additional, Colucci, R., additional, Conigliaro, R., additional, Danese, S., additional, Dumitrascu, D.L., additional, Escalante, R., additional, Faggiani, R., additional, Fiorella, S., additional, Forti, G., additional, Franceschi, M., additional, Giorgetti, G., additional, Grad, S., additional, Graziani, M.G., additional, Lai, M.A., additional, Lammert, F., additional, Latella, G., additional, Lisi, D., additional, Maconi, G., additional, Murphy, M.M., additional, Nardone, G., additional, De Oliveira, L. Camara, additional, De Oliveira, E. Chaves, additional, Papa, A., additional, Papagrigoriadis, S., additional, Penna, A., additional, Pietrzak, A., additional, Pontone, S., additional, Portincasa, P., additional, Poskus, T., additional, Pranzo, G., additional, Reichert, M., additional, Rizzo, G.L., additional, Rodinò, S., additional, Regula, J., additional, Scaccianoce, G., additional, Scaldaferri, F., additional, Schiffino, L., additional, Stundiene, I., additional, Vassallo, R., additional, Walker, M., additional, Zampaletta, C., additional, and Zullo, A., additional

Published
2019
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36. OC.05.6 THE PROGNOSTIC VALUE OF A NEW ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE: DICA (DIVERTICULAR INFLAMMATION AND COMPLICATION ASSESSMENT)

Author

Cambiè, G., primary, Violi, A., additional, Tursi, A., additional, Brandimarte, G., additional, Franceschi, M., additional, Franzoni, L., additional, Rodriguez-Castro, K.I., additional, Miraglia, C., additional, Baldassarre, G., additional, Nouvenne, A., additional, Crafa, P., additional, and Di Mario, F., additional

Published
2019
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37. OC.03.3 THE “DICA” ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE OF THE COLON SHOWS A SIGNIFICANT INTEROBSERVER AGREEMENT AMONG COMMUNITY ENDOSCOPISTS

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Nardone, G., additional, Scarpignato, C., additional, Picchio, M., additional, Elisei, W., additional, Allegretta, L., additional, Annunziata, M.L., additional, Astegiano, M., additional, Baldi, F., additional, Bassotti, G., additional, Bianco, M.A., additional, Cambiè, G., additional, Capezzuto, E., additional, Caroli, A., additional, Cassieri, C., additional, Cicu, A.S., additional, Ciliberto, E., additional, Colucci, R., additional, Conigliaro, R., additional, Damiani, A., additional, De Colibus, P., additional, De Medici, A., additional, De Pretis, G., additional, Favero, G. Del, additional, Valle, N. Della, additional, Di Cesare, L., additional, Faggiani, R., additional, Febbraro, S., additional, Ferrini, L., additional, Fiorella, S., additional, Forti, G., additional, Franceschi, M., additional, Frunzio, A., additional, Germanà, B., additional, Giorgetti, G., additional, Giovannone, M., additional, Graziani, M.G., additional, Lai, M.A., additional, Latella, G., additional, Lisi, D., additional, Lopetuso, L.R., additional, Maconi, G., additional, Mandelli, E.D., additional, Marmo, R., additional, Maurano, A., additional, Pallotta, L., additional, Papa, A., additional, Parmeggiani, F., additional, Penna, A., additional, Pigò, F., additional, Pontone, S., additional, Pranzo, G., additional, Ricciardelli, C., additional, Rizzo, G.L., additional, Rodinò, S., additional, Savarino, E., additional, Scaccianoce, G., additional, Scaldaferri, F., additional, Schiffino, L., additional, Semeraro, C., additional, Stroppa, I., additional, Urgesi, R., additional, Vassallo, R., additional, Violi, A., additional, Zampaletta, C., additional, Lecca, P.G., additional, Zilli, M., additional, and Zullo, A., additional

Published
2019
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39. Predictive value of the Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification on the outcome of diverticular disease of the colon: An international study

Author

Tursi A, Brandimarte G, Di Mario F, Annunziata ML, Bafutto M, Bianco MA, Colucci R, Conigliaro R, Danese S, De Bastiani R, Elisei W, Escalante R, Faggiani R, Ferrini L, Forti G, Latella G, Graziani MG, Oliveira EC, Papa A, Penna A, Portincasa P, Soreide K, Spadaccini A, Usai P, Bonovas S, Scarpignato C, Picchio M, Di Cesare L, Lecca PG, Zampaletta C, Cassieri C, Damiani A, Desserud KF, Fiorella S, Landi R, Goni E, Lai MA, Pigo F, Rotondano G, Schiaccianoce G, Tursi, A, Brandimarte, G, Di Mario, F, Annunziata, Ml, Bafutto, M, Bianco, Ma, Colucci, R, Conigliaro, R, Danese, S, De Bastiani, R, Elisei, W, Escalante, R, Faggiani, R, Ferrini, L, Forti, G, Latella, G, Graziani, Mg, Oliveira, Ec, Papa, A, Penna, A, Portincasa, P, Soreide, K, Spadaccini, A, Usai, P, Bonovas, S, Scarpignato, C, Picchio, M, Di Cesare, L, Lecca, Pg, Zampaletta, C, Cassieri, C, Damiani, A, Desserud, Kf, Fiorella, S, Landi, R, Goni, E, Lai, Ma, Pigo, F, Rotondano, G, and Schiaccianoce, G

Subjects
medicine.medical_specialty, Settore MED/12 - GASTROENTEROLOGIA, colon, Colonoscopy, diverticular disease, endoscopic classification, outcome, surgery, Oncology, Gastroenterology, Inflammation, digestive system, 03 medical and health sciences, 0302 clinical medicine, medicine, Special section on Fibrosis in Crohn's disease and inflammatory bowel disorders, medicine.diagnostic_test, business.industry, General surgery, digestive, oral, and skin physiology, medicine.disease, Predictive value, digestive system diseases, Surgery, Diverticulosis, surgical procedures, operative, 030220 oncology & carcinogenesis, Diverticular disease, 030211 gastroenterology & hepatology, medicine.symptom, Complication, business
Abstract

Background Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification has been recently developed for patients suffering from diverticulosis and diverticular disease. Aims We assessed retrospectively the predictive value of DICA in patients for whom endoscopic data and clinical follow-up were available. Methods For each patient, we recorded: age, severity of DICA, presence of abdominal pain, C-reactive protein and faecal calprotectin test (if available) at the time of diagnosis months of follow-up therapy taken during the follow-up to maintain remission (if any) occurrence/recurrence of diverticulitis need of surgery. Results We enrolled 1651 patients (793M, 858F, mean age 66.611.1 years): 939 (56.9%) patients were classified as DICA 1, 501 (30.3%) patients as DICA 2 and 211 (12.8%) patients as DICA 3. The median follow-up was 24 (9-38) months. Acute diverticulitis (AD) occurred/recurred in 263 (15.9%) patients surgery was necessary in 57 (21.7%) cases. DICA was the only factor significantly associated to the occurrence/recurrence of diverticulitis and surgery either at univariate ((2)=405.029 p

Published
2016

40. Effectiveness and Safety of Pylera® in Patients Infected by Helicobacter Pylori: A Multicenter, Retrospective, Real Life Study

Author

Tursi, A., Franceschi, M., Allegretta, L., Savarino, E., De Bastiani, R., Elisei, W., Baldassarre, G., Ferronato, A., Scida, S., Miraglia, C., Penna, A., Licci, C., Rizzo, G. L., Pranzo, G., Cassieri, C., Brandimarte, G., Picchio, M., and Di Mario, F.

Subjects
Male, Helicobacter pylori, Antibiotics, Bismuth-containing therapy, Safety, Treatment, Anti-Bacterial Agents, Bismuth, Demography, Drug Therapy, Combination, Endoscopy, Female, Helicobacter Infections, Humans, Metronidazole, Middle Aged, Organometallic Compounds, Retrospective Studies, Tetracycline, Treatment Outcome, Drug Therapy, Combination
Abstract

Our aims were to assess the real life effectiveness and safety of the new bismuth-containing quadruple therapy in a large population of patients infected by Helicobacter pylori.Consecutive dyspeptic H. pylori-positive patients were enrolled, both naïve for treatment and already unsuccessfully treated. Patients were treated with Pylera® 3 capsules 4 times/daily plus omeprazole 20 mg or esomeprazole 40 mg 2 times/daily for 10 days. Eradication was confirmed using a urea-breath test (at least 30 days after the end of the treatment). Efficacy and safety were assessed.A total of 349 patients were treated. H. pylori eradication was achieved in 316 (90.5%, 95% CIs 80.8-1.0) patients in the intention-to-treat population, and in 93.5% (95% CIs 83.5-1.0) in the per-protocol population. No difference in the eradication rate was found between naïve and previously treated patients (91.3 vs. 90.0%, p = 0.901). Adverse events occurred in 55 patients (15.8%, 95% CIs 11.9-20.1). Five patients discontinued treatment: 2 patients suffered from severe abdominal pain, one patient from headache, one patient from diarrhea, and one patient from diffuse urticarial rush.Pylera® achieved a remarkable eradication rate in real life both as first treatment and as a rescue therapy, with a good safety profile.

Published
2017

41. Confirmatory factor analysis of the Patient Assessment of Constipation-Symptoms (PAC-SYM) among patients with chronic constipation

Author

Neri L, Conway PM, Basilisco G, Altomare DF, Annese V, Badiali D, Bassotti G, Battaglia E, Bazzocchi G, Bellini M, Bendia E, Benini L, Biscaglia G, Biviano I, Bocchini R, Bonfrate L, Bonventre S, Bossa F, Brandimarte G, Cannizzaro R, Cicala M, Cipolletta L, Clara V, Cogliandro R, Comandini G, Corazziari E, Crotta S, CUOMO, ROSARIO, D'Alba L, De Giorgi F, Del Piano M, Di Fonzo M, Di Mario Francesco, Di Stefano M, D'Onofrio V, Efthymakis K, Fiore P, Fortuna M, Fries W, Gaetani E, Galeazzi F, Gasbarrini A, Geccherle' A, Giangregorio F, Girardi L, Grassini M, Groppo M, Guarnieri G, Iovino P, Lo Cascio M, Lolli R, Luzza F, Macarri G, Marino M, Miraglia S, Monastra S, Neri MC, Neri M, Noris RA, Orselli S, Passaretti S, Paviotti A, Pazzi P, Pilotto A, Portincasa P, Ranaldo N, Ravelli P, Rogai F, Sablich R, Savarino V, Spinzi G, Stanghellini V, Tammaro L, Torresan F, Usai Satta P, Valle C., Neri, L, Conway, Pm, Basilisco, G, Stanghellini, V, Neri, L., Conway, P., Basilisco, G., Bonventre, S, Altomare, Df, Annese, V, Badiali, D, Bassotti, G, Battaglia, E, Bazzocchi, G, Bellini, M, Bendia, E, Benini, L, Biscaglia, G, Biviano, I, Bocchini, R, Bonfrate, L, Bossa, F, Brandimarte, G, Cannizzaro, R, Cicala, M, Cipolletta, L, Clara, V, Cogliandro, R, Comandini, G, Corazziari, E, Crotta, S, Cuomo, Rosario, D'Alba, L, De Giorgi, F, Del Piano, M, Di Fonzo, M, Di Mario, Francesco, Di Stefano, M, D'Onofrio, V, Efthymakis, K, Fiore, P, Fortuna, M, Fries, W, Gaetani, E, Galeazzi, F, Gasbarrini, A, Geccherle', A, Giangregorio, F, Girardi, L, Grassini, M, Groppo, M, Guarnieri, G, Iovino, P, Lo Cascio, M, Lolli, R, Luzza, F, Macarri, G, Marino, M, Miraglia, S, Monastra, S, Neri, Mc, Neri, M, Noris, Ra, Orselli, S, Passaretti, S, Paviotti, A, Pazzi, P, Pilotto, A, Portincasa, P, Ranaldo, N, Ravelli, P, Rogai, F, Sablich, R, Savarino, V, Spinzi, G, Tammaro, L, Torresan, F, Usai Satta, P, and Valle, C.

Subjects
Adult, Male, medicine.medical_specialty, Abdominal pain, Constipation, Constipation severity, Chronic constipation, Chronic non-organic constipation, Quality of life, Chronic Disease, Female, Humans, Middle Aged, Patient Care, Quality of Life, Reproducibility of Results, Surveys and Questionnaires, Factor Analysis, Statistical, Public Health, Environmental and Occupational Health, Medicine (all), Reproducibility of Result, Internal medicine, medicine, Criterion validity, Surveys and Questionnaire, Settore MED/12 - Gastroenterologia, business.industry, Minimal clinically important difference, Environmental and Occupational Health, Settore MED/09 - MEDICINA INTERNA, Statistical, medicine.disease, Confirmatory factor analysis, Settore MED/18 - Chirurgia Generale, Physical therapy, Functional constipation, Public Health, medicine.symptom, business, Factor Analysis, Human
Abstract

Background and aim: PAC-SYM is widely adopted to asses constipation severity. However, it has been validated in a small sample, few items have been included based on expert opinion and not on empirical grounds, and its factor structure has never been replicated. We aimed at evaluating the psychometric properties of PAC-SYM in patients with chronic constipation. Methods: We enrolled 2,203 outpatients with chronic constipation in two waves. We used wave I sample to test the psychometric properties of the PAC-SYM and wave II sample to cross-validate its factor structure, to assess criterion validity, responsiveness to clinical change, and its minimal clinically important difference. Results: Only a minority of patients reported any rectal tearing (38 %). Deletion of such item leads to a 11-item version (M:PAC-SYM). The remaining items in the rectal domain were moderately correlated with the stool domain. Exploratory factor analysis and confirmatory factor analysis revealed a bifactor structure with two subscales (stool and abdominal symptoms) and a general severity factor. The M:PAC-SYM demonstrated excellent reliability, moderate correlation with SF-12 and treatment satisfaction (r = 0.28–0.45), discrimination across Rome III criteria for functional constipation and abdominal pain, and responsiveness to clinical change (β = −0.49; ω 2 = 0.25). M:PAC-SYM minimal clinically important difference was 0.24. Conclusion: Our analysis shows that the rectal domain may not represent a relevant cluster of symptoms for patients with chronic constipation. We developed a modified version of the PAC-SYM which might better represent symptom severity of most patients seeking care in gastroenterology referral centers

Published
2014

43. P.01.22 REFLUX ESOPHAGITIS AFTER H.P. ERADICATION: THE ROLE OF GASTRIC ACID SECRETION

Author

Scida, S., primary, Franceschi, M., additional, Miraglia, C., additional, Rodriguez, K., additional, Franzoni, L., additional, Bertelè, A., additional, Crafa, P., additional, Cannizzaro, R., additional, Baldassarre, G., additional, Dal Bo', N., additional, Tursi, A., additional, Brandimarte, G., additional, Rugge, M., additional, Scarpignato, C., additional, and Di Mario, F., additional

Published
2018
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46. P.06.24 HISTOLOGICAL GHRELIN EXPRESSION CORRELATES WITH ECL PROLIFERATION AND CHROMOGRANIN A IMMUNOEXPRESSION: A COMPARATIVE STUDY BETWEEN ATROPHIC AND NON-ATROPHIC GASTRITIS

Author

Crafa, P., primary, Noto, A., additional, Miraglia, C., additional, Campanini, N., additional, Franceschi, M., additional, Rugge, M., additional, Cannizzaro, R., additional, Tursi, A., additional, Franzoni, L., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2018
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47. P.06.14 EFFECTIVENESS AND SAFETY OF PYLERA ® IN PATIENTS INFECTED BY HELICOBACTER PYLORI: A LARGE, PROSPECTIVE, REAL LIFE STUDY

Author

Tursi, A., primary, Franceschi, M., additional, Allegretta, L., additional, Savarino, E., additional, De Bastiani, R., additional, Elisei, W., additional, Baldassarre, G., additional, Ferronato, A., additional, Penna, A., additional, Licci, C., additional, Rizzo, G.L., additional, Pranzo, G., additional, Cassieri, C., additional, Brandimarte, G., additional, Picchio, M., additional, Scida, S., additional, Miraglia, C., additional, and Di Mario, F., additional

Published
2018
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48. P.05.7 EPIDEMIOLOGY OF DIVERTICULAR DISEASE OF THE COLON: A PRELIMINARY ANALYSIS FROM THE INTERNATIONAL “DICA” PROSPECTIVE STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Elisei, W., additional, Picchio, M., additional, Annunziata, M.L., additional, Bafutto, M., additional, Bianco, M.A., additional, Costin, S., additional, Danese, S., additional, Dumitrascu, D., additional, Escalante, R., additional, Faggiani, R., additional, Franceschi, M., additional, Graziani, M.G., additional, Lammert, F., additional, Latella, G., additional, Maconi, G., additional, Murphy, M.M., additional, Nardone, G., additional, Oliveira, L., additional, Oliveira, E. Chaves, additional, Papa, P., additional, Papagrigoriadis, S., additional, Penna, A., additional, Pietrzak, A., additional, Reichert, M., additional, Rodinò, S., additional, Poskus, T., additional, Regula, J., additional, Scaldaferri, F., additional, Stundiene, L., additional, Vassallo, R., additional, and Marjorie, W., additional

Published
2018
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