Search

Superhydrophobic materials have found extensive applications in everyday life and various industries due to their outstanding attributes such as waterproofing, exceptional anti-corrosion and self-cleaning capabilities. Nonetheless, their limited mechanical stability hinders their widespread use on ceramic surfaces. This study aims to address these limitations by employing industrial waste porcelain powder as a raw material and co-firing technology to create a micro-rough structure on ceramic surfaces. Furthermore, the impact of this rough structure on the wear resistance and hydrophobicity of the hydrophobic coating is investigated using the finite element method. The results indicate that the mechanical stability of the hydrophobic coating experiences a more pronounced enhancement with increasing distribution density of the micron rough structure of waste porcelain powder (WPPMRS). A dense rough structure does not only reduce its concentrated stress and improve its anti-wear ability, but also reduce the concentrated stress of hydrophobic coating to improve the protection of the coating. As a result, it substantially enhances the mechanical properties and stability of the hydrophobic coating. This work will provide valuable insights into the utilization of waste porcelain powder in sustainable superhydrophobic ceramics.

Objective This retrospective study determined the storage time of finished infusion in each hospital ward and assessed whether the storage time of finished infusion was within an acceptable range. Methods The research object was the finished infusion (one bag of infusion with only one drug) that is centrally dosed at the Pharmacy Intravenous Admixture Service (PIVAS) of Jiading District Central Hospital Affiliated Shanghai University of Medicine & Health Sciences. We used an automatic scanner to assess the placement time of finished infusion products in various wards of the hospital. We classified the drugs used in various wards, analyzed whether their placement times were reasonable, assessed the reasons for unreasonable placement times, and took intervention measures. Similarly, the storage time of finished infusion was deemed reasonable or unreasonable, the reasons for unreasonable storage times were analyzed, and intervention measures were taken. Results In September 2021, the proportion of infusions stored for an unreasonable time was 12.69%, a decrease of 5.37% compared with August 2021, indicating the effectiveness of intervention measures. Conclusion By using statistical analysis and intervention measures, our PIVAS improved the standardized use of finished infusion products and ensured the safety of medication for patients.

Abstract During storage, duloxetine hydrochloride may have an unexpected cross reaction with enteric coated acrylic resin, which may affect the product quality. Solve the problem of cross-reaction between the Duloxetine enteric-coated tablets core and coated enteric materials and improve the quality of the products. Duloxetine enteric-coated tablets’ core formulation and isolation layer prescription were designed and compared with duloxetine enteric-coated tablets sold on the market. Then, we measured the dissolution rate, content, and releasing rate of prepared duloxetine enteric-coated tablets. In the formulation of tablets core, prescription 3 had advantages in particle mobility, disintegration time, and dissolution rate. Prescription 5 was stable during the coating process, and the dissolution residue in the cup was relatively good, showing obvious dissolution advantages. Thus, prescription 5 was selected as the isolation layer prescription. The most suitable adhesive for the preparation of Duloxetine hydrochloride enteric-coated tablets was povione K30 dissolved in ethanol solution with 1/2 of the prescription amount. When 1.3 g colloidal silica was added to the prescription and the dosage of magnesium stearate was 1.48 g, the dissolution rate of the drug could be relatively improved. The ratio of sucrose and talc was 138/8.7, which could effectively configure the coating solution with a solid content of 15–20% to make the coating smooth.

Though an experiment of exposing Daphnia magna and recovering its offspring for both 21 days, the chronic toxicity of perfluorooctane sulfonate (PFOS) to Daphnia magna and its first and third broods F1 (1st) and F1 (3rd) were investigated. Results show that when the mass concentration of PFOS is higher than 20 mg/L, the number of offspring, length and innate increase rate are significantly inhibited. Compared with the control group, the reduction of the three indicators under the highest exposure concentration are 62.2%, 40.6%, 34.0% (p<0.01), respectively. The toxic effect becomes more serious with gradually increasing of exposure concentration, which shows an obvious dose-response relationship between PFOS concentration of exposure and the toxicity to Daphnia magna. The number of offspring and length of the F1 (1st) generation are significantly inhibited when PFOS mass concentration is higher than 30 mg/L. The F1 (3rd) generation's recovery extent is better than that of the F1 (3rd) generation, and all the indicators recover closely to those of the control group except that the number of offspring, length and innate rate of increase are significantly inhibited when the Daphnia magna is exposed to the PFOS of 50 mg/L. As the most sensitive indicator, the number of offspring, length and innate rate of increase of Daphnia magna are suggested for evaluation of PFOS chronic toxicity. [ABSTRACT FROM AUTHOR]