1. Synchronous carcinosarcoma of the uterine cervix with adenoid basal carcinoma and cervical intraepithelial neoplasia III: A case report and literature review.
- Author
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Lin Y, Chen H, Ye Z, Ding L, Cao Q, and Xue L
- Subjects
- Adenoids pathology, Aged, Carcinosarcoma complications, Carcinosarcoma pathology, Carcinosarcoma virology, Cervix Uteri pathology, Female, Humans, Neoplasms, Multiple Primary complications, Neoplasms, Multiple Primary pathology, Neoplasms, Multiple Primary virology, Papillomavirus Infections complications, Papillomavirus Infections pathology, Papillomavirus Infections virology, Uterine Cervical Neoplasms complications, Uterine Cervical Neoplasms pathology, Uterine Cervical Neoplasms virology, Uterine Cervical Dysplasia complications, Uterine Cervical Dysplasia pathology, Uterine Cervical Dysplasia virology, Carcinosarcoma diagnosis, Neoplasms, Multiple Primary diagnosis, Papillomaviridae isolation & purification, Papillomavirus Infections diagnosis, Uterine Cervical Neoplasms diagnosis, Uterine Cervical Dysplasia diagnosis
- Abstract
Carcinosarcoma and adenoid basal carcinoma (ABC) are both rare lesions in uterine cervix. There were only 5 cases of cervical carcinosarcoma combined with ABC and/without cervical intraepithelial neoplasia (CIN) reported in English literature. These limited studies showed that there was a strong association between HPV, carcinosarcoma, ABC and CIN, suggesting a common etiology for these lesions. Here, we present the case of a 65-year-old woman with cervical carcinosarcoma combined with ABC and CIN III. However, HPV-16, 18, 31 and 33 was negative in the cervical carcinosarcoma tissue by in situ hybridization detection. It indicated that there might be other subtype of HPV involved, or, HPV might play a role in some but not all cervical carcinosarcomas., (Copyright © 2017 Elsevier GmbH. All rights reserved.)
- Published
- 2017
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