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In early 2020, Edith Cowan University (ECU) identified the need for a proactive approach to supporting and affirming trans, gender diverse, and non-binary (TGDNB) students, staff, alumni, and the wider community. While there was general support and focus on LGBTIQA+ initiatives broadly at ECU, there were no existing supports to address the unique needs and raise awareness of the experiences of TGDNB people. This paper outlines ECU’s process to develop TGDNB Support Guidelines, including research, forming a working group to drive resource development, consultation from different areas within the university, a launch event, training, and ensuring the document was widely promoted and used after the launch. The paper also identifies the issues TGDNB students are facing, outcomes of the continued work to advocate for trans people at ECU, as well as the challenges we face and goals we continue to work toward. ... Beyond inclusion: Developing guidelines to support trans, gender diverse and non-binary communities by Stevie Lane & Casey Thomas is licensed under CC BY 4.0

This case study examines the political and social pressures high school social studies teachers face in rural areas. In the political sphere, many social studies teachers focus on the end of course exam. The resources that informed this study were public materials on the web. Findings indicate teachers stay to state tested content.

Intrinsically disordered proteins rich in cationic amino acid groups can undergo Liquid-Liquid Phase Separation (LLPS) in the presence of charge-balancing anionic counterparts. Arginine and Lysine are the two most prevalent cationic amino acids in proteins that undergo LLPS, with arginine-rich proteins observed to undergo LLPS more readily than lysine-rich proteins, a feature commonly attributed to arginine's ability to form stronger cation-π interactions with aromatic groups. Here, we show that arginine's ability to promote LLPS is independent of the presence of aromatic partners, and that arginine-rich peptides, but not lysine-rich peptides, display re-entrant phase behavior at high salt concentrations. We further demonstrate that the hydrophobicity of arginine is the determining factor giving rise to the reentrant phase behavior and tunable viscoelastic properties of the dense LLPS phase. Controlling arginine-induced reentrant LLPS behavior using temperature and salt concentration opens avenues for the bioengineering of stress-triggered biological phenomena and drug delivery systems.

Hydration water dynamics, structure, and thermodynamics are crucially important to understand and predict water-mediated properties at molecular interfaces. Yet experimentally and directly quantifying water behavior locally near interfaces at the sub-nanometer scale is challenging, especially at interfaces submerged in biological solutions. Overhauser dynamic nuclear polarization (ODNP) experiments measure equilibrium hydration water dynamics within 8–15 angstroms of a nitroxide spin probe on instantaneous timescales (10 picoseconds to nanoseconds), making ODNP a powerful tool for probing local water dynamics in the vicinity of the spin probe. As with other spectroscopic techniques, concurrent computational analysis is necessary to gain access to detailed molecular level information about the dynamic, structural, and thermodynamic properties of water from experimental ODNP data. We chose a model system that can systematically tune the dynamics of water, a water–glycerol mixture with compositions ranging from 0 to 0.3 mole fraction glycerol. We demonstrate the ability of molecular dynamics (MD) simulations to compute ODNP spectroscopic quantities, and show that translational, rotational, and hydrogen bonding dynamics of hydration water align strongly with spectroscopic ODNP parameters. Moreover, MD simulations show tight correlations between the dynamic properties of water that ODNP captures and the structural and thermodynamic behavior of water. Hence, experimental ODNP readouts of varying water dynamics suggest changes in local structural and thermodynamic hydration water properties. [ABSTRACT FROM AUTHOR]

Gender gaps in physical activity (PA) exist with women being less active than men. Multiple cultural and psychosocial factors influence women's ability to successfully negotiate barriers to PA and other health promoting behaviors. The goal of this exploratory descriptive study was to better understand the daily experiences of mothers in making health promoting decisions for themselves and their families. Semi-structured interviews (N = 17) were conducted with rural dwelling mothers who were the primary caregivers of children in the home. Participants were asked to share their experiences with PA and other health behaviors, focusing on their motivators, barriers, and facilitators. Interviews were audio-recorded, transcribed verbatim, and analyzed using thematic content analysis. Emerging themes focused on 1) feeling internal and external pressures to prioritize family's needs over one's health, 2) family exerting both positive and negative influences on health choices, and 3) living in a rural community often resulting in a lack of opportunities to engage in physical activity and feelings of being isolated from social networks. To close the gender gap in PA, interventions should support mothers in navigating their multiple roles and competing demands while engaging in health promoting behaviors such as physical activity. [ABSTRACT FROM AUTHOR]

This case study examines the political and social pressures high school social studies teachers face in rural areas. In the political sphere, many social studies teachers focus on the end of course exam. The resources that informed this study were public materials on the web. Findings indicate teachers stay to state tested content. [ABSTRACT FROM AUTHOR]