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Your search keyword '"Chang, Shwu-Jen"' showing total 32 results
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32 results on '"Chang, Shwu-Jen"'

25. The study of cardiac differentiation of mesenchymal stem cells by electrostimulation on the myocardial repair

Author

Lin Yu-Hsin, Chang Shwu Jen, Chu Jou-Hsuan, Kang Pei-Leun, and Chen Shu-Ying

Subjects
0301 basic medicine, 030103 biophysics, Pathology, medicine.medical_specialty, Histology, business.industry, Cardiac differentiation, Mesenchymal stem cell, Biomedical Engineering, Bioengineering, 03 medical and health sciences, Medicine, business, Biotechnology, Stem cell transplantation for articular cartilage repair
Published
2016

26. The study of the prevention dressing of keloid

Author

Lee Ming-Wei, Kuo Shyh Ming, Chang Shwu Jen, Yao Chun-Hsu, and Chen Fang-Yi

Subjects
medicine.medical_specialty, Histology, Keloid, business.industry, Biomedical Engineering, Medicine, Bioengineering, business, medicine.disease, Dermatology, Biotechnology
Published
2016

31. Development of chondrocyte-seeded electrosprayed nanoparticles for repair of articular cartilage defects in rabbits.

Author

Yang, Shan-Wei, Ku, Kai-Chi, Chen, Shu-Ying, Kuo, Shyh-Ming, Chen, I-Fen, Wang, Ting-Yi, and Chang, Shwu-Jen

Subjects
CARTILAGE cells, NANOPARTICLES, ARTICULAR cartilage injuries, CELL proliferation, CELL transplantation, LABORATORY rabbits
Abstract

Due to limited self-healing capacity in cartilages, there is a rising demand for an innovative therapy that promotes chondrocyte proliferation while maintaining its biofunctionality for transplantation. Chondrocyte transplantation has received notable attention; however, the tendencies of cell de-differentiation and de-activation of biofunctionality have been major hurdles in its development, delaying this therapy from reaching the clinic. We believe it is due to the non-stimulative environment in the injured cartilage, which is unable to provide sustainable physical and biological supports to the newly grafted chondrocytes. Therefore, we evaluated whether providing an appropriate matrix to the transplanted chondrocytes could manipulate cell fate and recovery outcomes. Here, we proposed the development of electrosprayed nanoparticles composed of cartilage specific proteins, namely collagen type II and hyaluronic acid, for implantation with pre-seeded chondrocytes into articular cartilage defects. The fabricated nanoparticles were pre-cultured with chondrocytes before implantation into injured articular cartilage. The study revealed a significant potential for nanoparticles to support pre-seeded chondrocytes in cartilage repair, serving as a protein delivery system while improving the survival and biofunctionality of transplanted chondrocytes for prolonged period of time. [ABSTRACT FROM AUTHOR]

Published
2018
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