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169 results on '"Chasekwa, Bernard"'

1. Quality of vital event data for infant mortality estimation in prospective, population-based studies: an analysis of secondary data from Asia, Africa, and Latin America

Author

Erchick, Daniel J., Subedi, Seema, Verhulst, Andrea, Guillot, Michel, Adair, Linda S., Barros, Aluísio J. D., Chasekwa, Bernard, Christian, Parul, da Silva, Bruna Gonçalves C., Silveira, Mariângela F., Hallal, Pedro C., Humphrey, Jean H., Huybregts, Lieven, Kariuki, Simon, Khatry, Subarna K., Lachat, Carl, Matijasevich, Alicia, McElroy, Peter D., Menezes, Ana Maria B., Mullany, Luke C., Perez, Tita Lorna L., Phillips-Howard, Penelope A., Roberfroid, Dominique, Santos, Iná S., ter Kuile, Feiko O., Ravilla, Thulasiraj D., Tielsch, James M., Wu, Lee S. F., and Katz, Joanne

Published
2023
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2. The gut microbiome and early-life growth in a population with high prevalence of stunting

Author

Robertson, Ruairi C., Edens, Thaddeus J., Carr, Lynnea, Mutasa, Kuda, Gough, Ethan K., Evans, Ceri, Geum, Hyun Min, Baharmand, Iman, Gill, Sandeep K., Ntozini, Robert, Smith, Laura E., Chasekwa, Bernard, Majo, Florence D., Tavengwa, Naume V., Mutasa, Batsirai, Francis, Freddy, Tome, Joice, Stoltzfus, Rebecca J., Humphrey, Jean H., Prendergast, Andrew J., and Manges, Amee R.

Published
2023
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3. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting

Author

Ashorn, Per, Black, Robert E, Lawn, Joy E, Ashorn, Ulla, Klein, Nigel, Hofmeyr, G Justus, Temmerman, Marleen, Askari, Sufia, Ohuma, Eric O, Moller, Ann-Beth, Bradley, Ellen, Chakwera, Samuel, Hussain-Alkhateeb, Laith, Lewin, Alexandra, Okwaraji, Yemisrach B, Retno Mahanani, Wahyu, White Johansson, Emily, Lavin, Tina, Estevez Fernandez, Diana, Gatica Domínguez, Giovanna, de Costa, Ayesha, Cresswell, Jenny A, Krasevec, Julia, Blencowe, Hannah, Requejo, Jennifer, Moran, Allisyn C, Pingray, Veronica, Cormick, Gabriela, Gibbons, Luz, Belizan, José, Guevel, Carlos, Warrilow, Kara, Gordon, Adrienne, Flenady, Vicki, Sexton, Jessica, Lawford, Harriet, Paixao, Enny S., Rocha Falcão, Ila, Lima Barreto, Mauricio, Lisonkova, Sarka, Wen, Qi, Mardones, Francisco, Caulier-Cisterna, Raúl, Acuña, José, Velebil, Petr, Jirova, Jitka, Horváth-Puhó, Erzsébet, Sørensen, Henrik Toft, Sakkeus, Luule, Abuladze, Liili, Gissler, Mika, Moradi-Lakeh, Maziar, Heidarzadeh, Mohammad, Khalili, Narjes, A. Yunis, Khalid, Al Bizri, Ayah, Nakad, Pascale, Devi Karalasingam, Shamala, R Jeganathan, J Ravichandran, binti Baharum, Nurakman, Suárez-Idueta, Lorena, Barranco Flores, Arturo, Gonzalez Roldan, Jesus F, Lopez Alvarez, Sonia, van Dijk, Aimée E., Broeders, Lisa, Huicho, Luis, Quezada Pinedo, Hugo G, Cajachagua-Torres, Kim N, Carrillo-Larco, Rodrigo M, Tarazona Meza, Carla Estefania, Guzman-Vilca, Wilmer Cristobal, Olukade, Tawa O., Ali, Hamdy A., Alyafei, Fawziya, AlQubaisi, Mai, Alturk, Mohamad R, Kim, Ho Yeon, Cho, Geum Joon, Razaz, Neda, Söderling, Jonas, Smith, Lucy K, Kurinczuk, Jennifer J, Matthews, Ruth J, Manktelow, Bradley N, Draper, Elizabeth S, Fenton, Alan C, Lowry, Estelle, Rowland, Neil, Wood, Rachael, Monteath, Kirsten, Pereyra, Isabel, Pravia, Gabriella, Davis, Celina, Clarke, Samantha, Wu, Lee S.F., Yoshida, Sachiyo, Bahl, Rajiv, Grandi, Carlos, Labrique, Alain B, Rashid, Mabhubur, Ahmed, Salahuddin, Roy, Arunangshu D., Haque, Rezwanul, Shaikh, Saijuddin, Baqui, Abdullah H., Saha, Samir K., Khanam, Rasheda, Rahman, Sayedur, Shapiro, Roger, Zash, Rebecca, Silveira, Mariângela F., Buffarini, Romina, Kolsteren, Patrick, Lachat, Carl, Huybregts, Lieven, Roberfroid, Dominique, Zeng, Lingxia, Zhu, Zhonghai, He, Jianrong, Qui, Xiu, Gebreyesus, Seifu H., Tesfamariam, Kokeb, Bekele, Delayehu, Chan, Grace, Baye, Estifanos, Workneh, Firehiwot, Asante, Kwaku P., Boanmah-Kaali, Ellen, Adu-Afarwuah, Seth, Dewey, Kathryn G., Gyaase, Stephaney, Wylie, Blair J., Kirkwood, Betty R., Manu, Alexander, Thulasiraj, Ravilla D, Tielsch, James, Chowdhury, Ranadip, Taneja, Sunita, Babu, Giridhara R, Shriyan, Prafulla, Maleta, Kenneth, Mangani, Charles, Acevedo-Gallegos, Sandra, Rodriguez-Sibaja, Maria J., Khatry, Subarna K., LeClerq, Steven C., Mullany, Luke C., Jehan, Fyezah, Ilyas, Muhammad, Rogerson, Stephen J., Unger, Holger W., Ghosh, Rakesh, Musange, Sabine, Ramokolo, Vundli, Zembe-Mkabile, Wanga, Lazzerini, Marzia, Mohamed, Rishard, Wang, Dongqing, Fawzi, Wafaie W., Minja, Daniel T.R., Schmiegelow, Christentze, Masanja, Honorati, Smith, Emily, Lusingu, John P.A., Msemo, Omari A., Kabole, Fathma M., Slim, Salim N., Keentupthai, Paniya, Mongkolchati, Aroonsri, Kajubi, Richard, Kakuru, Abel, Waiswa, Peter, Walker, Dilys, Hamer, Davidson H., Semrau, Katherine E.A., Chaponda, Enesia B., Chico, R. Matthew, Banda, Bowen, Musokotwane, Kebby, Manasyan, Albert, Pry, Jake M., Chasekwa, Bernard, Humphrey, Jean, Shamim, Abu Ahmed, Christian, Parul, Ali, Hasmot, Klemm, Rolf D.W., Massie, Alan B., Mitra, Maithili, Mehra, Sucheta, Schulze, Kerry J., Shamim, Abu Amed, Sommer, Alfred, Ullah, Barkat, West, Keith P., Jr, Begum, Nazma, Chowdhury, Nabidul Haque, Islam, Shafiqul, Mitra, Dipak Kumar, Quaiyum, Abdul, Diseko, Modiegi, Makhema, Joseph, Cheng, Yue, Guo, Yixin, Yuan, Shanshan, Roro, Meselech, Shikur, Bilal, Goddard, Frederick, Haneuse, Sebastien, Hunegnaw, Bezawit, Berhane, Yemane, Worku, Alemayehu, Kaali, Seyram, Arnold, Charles D., Jack, Darby, Amenga-Etego, Seeba, Hurt, Lisa, Shannon, Caitlin, Soremekun, Seyi, Bhandari, Nita, Martines, Jose, Mazumder, Sarmila, Ana, Yamuna, R, Deepa, Hallamaa, Lotta, Pyykkö, Juha, Lumbreras-Marquez, Mario I., Mendoza-Carrera, Claudia E., Hussain, Atiya, Karim, Muhammad, Kausar, Farzana, Mehmood, Usma, Nadeem, Naila, Nisar, Muhammad Imran, Sajid, Muhammad, Mueller, Ivo, Ome-Kaius, Maria, Butrick, Elizabeth, Sayinzoga, Felix, Mariani, Ilaria, Urassa, Willy, Theander, Thor, Deloron, Phillippe, Nielsen, Birgitte Bruun, Muhihi, Alfa, Noor, Ramadhani Abdallah, Bygbjerg, Ib, Moeller, Sofie Lykke, Aftab, Fahad, Ali, Said M., Dhingra, Pratibha, Dhingra, Usha, Dutta, Arup, Sazawal, Sunil, Suleiman, Atifa, Mohammed, Mohammed, Deb, Saikat, Kamya, Moses R., Nakalembe, Miriam, Mulowooz, Jude, Santos, Nicole, Biemba, Godfrey, Herlihy, Julie M., Mbewe, Reuben K., Mweena, Fern, Yeboah-Antwi, Kojo, Bruce, Jane, Chandramohan, Daniel, Prendergast, Andrew, Idueta, Lorena Suárez, Hazel, Elizabeth, Erchick, Daniel J, Yargawa, Judith, Katz, Joanne, Lee, Anne C C, Diaz, Mike, Salasibew, Mihretab, Hayashi, Chika, and Borghi, Elaine

Published
2023
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4. Inflammation and cytomegalovirus viremia during pregnancy drive sex-differentiated differences in mortality and immune development in HIV-exposed infants

Author

Evans, Ceri, primary, Mutasa, Kuda, additional, Rukobo, Sandra, additional, Govha, Margaret, additional, Mushayanembwa, Patience, additional, Chasekwa, Bernard, additional, Majo, Florence D., additional, Tavengwa, Naume V., additional, Broad, Jonathan, additional, Noble, Christie, additional, Gough, Ethan K., additional, Kelly, Paul, additional, Bourke, Claire D., additional, Humphrey, Jean H., additional, Ntozini, Robert, additional, and Prendergast, Andrew J., additional

Published
2024
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7. Maternal inflammatory and microbial drivers of low birthweight in low- and middle-income countries.

Author

Broad, Jonathan, Robertson, Ruairi C., Evans, Ceri, Perussolo, Jeniffer, Lum, Gina, Piper, Joe D., Loucaides, Eva, Ziruma, Asaph, Chasekwa, Bernard, Ntozini, Robert, Bourke, Claire D., and Prendergast, Andrew J.

Subjects
MIDDLE-income countries, PREMATURE labor, COMMUNICABLE diseases, GREY literature, BIRTH weight
Abstract

Low birthweight (LBW) is when an infant is born too soon or too small, and it affects one in seven infants in low- and middle-income countries. LBW has a significant impact on short-term morbidity and mortality, and it impairs long-term health and human capital. Antenatal microbial and inflammatory exposure may contribute to LBW. Ovid-Medline, Embase and Cochrane databases were searched for English-language articles evaluating inflammatory, microbial or infective causes of LBW, small-for-gestational age, intra-uterine growth restriction or prematurity. Inclusion criteria were human studies including published data; conference abstracts and grey literature were excluded. A narrative synthesis of the literature was conducted. Local infections may drive the underlying causes of LBW: for example, vaginitis and placental infection are associated with a greater risk of prematurity. Distal infection and inflammatory pathways are also associated with LBW, with an association between periodontitis and preterm delivery and environmental enteric dysfunction and reduced intra-uterine growth. Systemic maternal infections such as malaria and HIV are associated with LBW, even when infants are exposed to HIV but not infected. This latter association may be driven by chronic inflammation, co-infections and socio-economic confounders. Antimicrobial prophylaxis against other bacteria in pregnancy has shown minimal impact in most trials, though positive effects on birthweight have been found in some settings with a high infectious disease burden. Maternal inflammatory and infective processes underlie LBW, and provide treatable pathways for interventions. However, an improved understanding of the mechanisms and pathways underlying LBW is needed, given the impact of LBW on life-course. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Inflammation and epithelial repair predict mortality, hospital readmission, and growth recovery in complicated severe acute malnutrition

Author

Sturgeon, Jonathan P., primary, Tome, Joice, additional, Dumbura, Cherlynn, additional, Majo, Florence D., additional, Ngosa, Deophine, additional, Mutasa, Kuda, additional, Zyambo, Kanekwa, additional, Besa, Ellen, additional, Chandwe, Kanta, additional, Kapoma, Chanda, additional, Mwapenya, Benjamin, additional, Nathoo, Kusum J., additional, Bourke, Claire D., additional, Ntozini, Robert, additional, Chasekwa, Bernard, additional, Smuk, Melanie, additional, Bwakura-Dangarembizi, Mutsa, additional, Amadi, Beatrice, additional, Kelly, Paul, additional, and Prendergast, Andrew J., additional

Published
2024
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9. Associations between biomarkers of environmental enteric dysfunction and oral rotavirus vaccine immunogenicity in rural Zimbabwean infants

Author

Church, James A, Rukobo, Sandra, Govha, Margaret, Gough, Ethan K, Chasekwa, Bernard, Lee, Benjamin, Carmolli, Marya P, Panic, Gordana, Giallourou, Natasa, Ntozini, Robert, Mutasa, Kuda, McNeal, Monica M, Majo, Florence D., Tavengwa, Naume V., Swann, Jonathan R., Moulton, Lawrence H, Kirkpatrick, Beth D, Humphrey, Jean H, and Prendergast, Andrew J

Published
2021
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10. Neonatal mortality risk of vulnerable newborns by fine stratum of gestational age and birthweight for 230 679 live births in nine low‐ and middle‐income countries, 2000–2017

Author

Hazel, Elizabeth A., primary, Erchick, Daniel J., additional, Katz, Joanne, additional, Lee, Anne C. C., additional, Diaz, Michael, additional, Wu, Lee S. F., additional, West, Keith P., additional, Shamim, Abu Ahmed, additional, Christian, Parul, additional, Ali, Hasmot, additional, Baqui, Abdullah H., additional, Saha, Samir K., additional, Ahmed, Salahuddin, additional, Roy, Arunangshu Dutta, additional, Silveira, Mariângela F., additional, Buffarini, Romina, additional, Shapiro, Roger, additional, Zash, Rebecca, additional, Kolsteren, Patrick, additional, Lachat, Carl, additional, Huybregts, Lieven, additional, Roberfroid, Dominique, additional, Zhu, Zhonghai, additional, Zeng, Lingxia, additional, Gebreyesus, Seifu H., additional, Tesfamariam, Kokeb, additional, Adu‐Afarwuah, Seth, additional, Dewey, Kathryn G., additional, Gyaase, Stephaney, additional, Poku‐Asante, Kwaku, additional, Boamah Kaali, Ellen, additional, Jack, Darby, additional, Ravilla, Thulasiraj, additional, Tielsch, James, additional, Taneja, Sunita, additional, Chowdhury, Ranadip, additional, Ashorn, Per, additional, Maleta, Kenneth, additional, Ashorn, Ulla, additional, Mangani, Charles, additional, Mullany, Luke C., additional, Khatry, Subarna K., additional, Ramokolo, Vundli, additional, Zembe‐Mkabile, Wanga, additional, Fawzi, Wafaie W., additional, Wang, Dongqing, additional, Schmiegelow, Christentze, additional, Minja, Daniel, additional, Msemo, Omari Abdul, additional, Lusingu, John P. A., additional, Smith, Emily R., additional, Masanja, Honorati, additional, Mongkolchati, Aroonsri, additional, Keentupthai, Paniya, additional, Kakuru, Abel, additional, Kajubi, Richard, additional, Semrau, Katherine, additional, Hamer, Davidson H., additional, Manasyan, Albert, additional, Pry, Jake M., additional, Chasekwa, Bernard, additional, Humphrey, Jean, additional, and Black, Robert E., additional

Published
2024
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11. Early child development in children who are HIV-exposed uninfected compared to children who are HIV-unexposed: observational sub-study of a cluster-randomized trial in rural Zimbabwe

Author

Ntozini, Robert, Chandna, Jaya, Evans, Ceri, Chasekwa, Bernard, Majo, Florence D., Kandawasvika, Gwendoline, Tavengwa, Naume V., Mutasa, Batsirai, Mutasa, Kuda, Moulton, Lawrence H., Humphrey, Jean H., Gladstone, Melissa J., and Prendergast, Andrew J.

Subjects
Clinical trials -- Research -- Comparative analysis, Infants -- Comparative analysis -- Research, HIV -- Research, Sanitation -- Research -- Comparative analysis, Pregnant women -- Research -- Comparative analysis, Health
Abstract

Introduction: Exposure to maternal HIV may affect early child development (ECD), although previous studies have reported heterogeneous findings. We evaluated ECD among children who were HIV-exposed uninfected (CHEU) and children who were HIV-unexposed (CHU) recruited to the SHINE trial in rural Zimbabwe. Methods: SHINE was a community-based cluster-randomized trial of improved infant feeding and/or improved water, sanitation and hygiene. Pregnant women were enrolled between 2012 and 2015. We assessed ECD in a sub-study at 24 months of age, between 2016 and 2017, using the Malawi Developmental Assessment Tool (MDAT; assessing motor, cognitive, language and social development); MacArthur-Bates Communicative Development Inventory (CDI) (assessing vocabulary and grammar); A-not-B test (assessing object permanence); and a self-control task. Mothers and infants were tested longitudinally for HIV. We used generalized estimating equations to compare ECD scores between CHEU and CHU, accounting for the cluster-randomized design. Primary results were adjusted for trial-related factors that could affect measurement reliability of ECD: study nurse, age of child, calendar month of birth, sex and randomized arm. Results: A total of 205 CHEU and 1175 CHU were evaluated. Mean total MDAT score was 90.6 (SD 8.7) in CHEU compared to 92.4 (9.1) in CHU (adjusted mean difference -1.3, 95% CI: -2.3, -0.3), driven mostly by differences in gross motor (-0.5, 95% CI: -0.9, -0.2) and language scores (-0.6, 95% CI: -1.1, -0.1). There was evidence that fine motor scores were lower in CHEU (adjusted mean difference -0.4, 95% CI: -0.8, 0.0) but no evidence of a difference in social scores (0.1, 95% CI: -0.2, 0.4). Mean MacArthur-Bates CDI vocabulary score was 57.9 (SD 19.2) in CHEU compared to 61.3 (18.8) in CHU (adjusted mean difference -2.9 words, 95% CI: -5.7, -0.1). Object permanence and self-control scores were similar between groups. Conclusions: CHEU in rural Zimbabwe had total child development and vocabulary scores that were approximately 0.15 standard deviations lower than CHU at two years of age. More detailed and specific studies are now needed to unravel the reasons for developmental delay in CHEU and the likelihood that these delays persist in the longer term. Keywords: child development; language; motor; self-control; HIV-exposed uninfected; Zimbabwe, 1 | INTRODUCTION The increasing coverage of prevention of mother-to-child transmission (PMTCT) interventions in sub-Saharan Africa has dramatically reduced the number of children with HIV infection. However, this success has [...]

Published
2020
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12. Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe: a cluster-randomised trial

Author

Humphrey, Jean H, Jones, Andrew D, Manges, Amee, Mangwadu, Goldberg, Maluccio, John A, Mbuya, Mduduzi N N, Moulton, Lawrence H, Ntozini, Robert, Prendergast, Andrew J, Stoltzfus, Rebecca J, Tielsch, James M, Chasokela, Cynthia, Chigumira, Ancikaria, Heylar, William, Hwena, Preston, Kembo, George, Majo, Florence D, Mutasa, Batsirai, Mutasa, Kuda, Rambanepasi, Philippa, Sauramba, Virginia, Tavengwa, Naume V, Van Der Keilen, Franne, Zambezi, Chipo, Chidhanguro, Dzivaidzo, Chigodora, Dorcas, Chipanga, Joseph F, Gerema, Grace, Magara, Tawanda, Mandava, Mandava, Mavhudzi, Tafadzwa, Mazhanga, Clever, Muzaradope, Grace, Mwapaura, Marian T, Phiri, Simon, Tengende, Alice, Banda, Cynthia, Chasekwa, Bernard, Chidamba, Leah, Chidawanyika, Theodore, Chikwindi, Elisha, Chingaona, Lovemore K, Chiorera, Courage K, Dandadzi, Adlight, Govha, Margaret, Gumbo, Hlanai, Gwanzura, Karen T, Kasaru, Sarudzai, Makasi, Rachel, Matsika, Alois M, Maunze, Diana, Mazarura, Exevia, Mpofu, Eddington, Mushonga, Johnson, Mushore, Tafadzwa E, Muzira, Tracey, Nembaware, Netsai, Nkiwane, Sibongile, Nyamwino, Penias, Rukobo, Sandra D, Runodamoto, Thompson, Seremwe, Shepherd, Simango, Pururudzai, Tome, Joice, Tsenesa, Blessing, Amadu, Umali, Bangira, Beauty, Chiveza, Daniel, Hove, Priscilla, Jombe, Horaiti A, Kujenga, Didymus, Madhuyu, Lenin, Makoni, Prince M, Maramba, Naume, Maregere, Betty, Marumani, Ellen, Masakadze, Elisha, Mazula, Phathisiwe, Munyanyi, Caroline, Musanhu, Grace, Mushanawani, Raymond C, Mutsando, Sibongile, Nazare, Felicia, Nyarambi, Moses, Nzuda, Wellington, Sigauke, Trylife, Solomon, Monica, Tavengwa, Tendai, Biri, Farisai, Chafanza, Misheck, Chaitezvi, Cloud, Chauke, Tsundukani, Chidzomba, Collen, Dadirai, Tawanda, Fundira, Clemence, Gambiza, Athanasios C, Godzongere, Tatenda, Kuona, Maria, Mafuratidze, Tariro, Mapurisa, Idah, Mashedze, Tsitsi, Moyo, Nokuthula, Musariri, Charles, Mushambadope, Matambudzo, Mutsonziwa, Tawanda R, Muzondo, Augustine, Mwareka, Rudo, Nyamupfukudza, Juleika, Saidi, Baven, Sakuhwehwe, Tambudzai, Sikalima, Gerald, Tembe, Jenneth, Chekera, Tapiwanashe E, Chihombe, Owen, Chikombingo, Muchaneta, Chirinda, Tichaona, Chivizhe, Admire, Hove, Ratidzai, Kufa, Rudo, Machikopa, Tatenda F, Mandaza, Wilbert, Mandongwe, Liberty, Manhiyo, Farirai, Manyaga, Emmanuel, Mapuranga, Peter, Matimba, Farai S, Matonhodze, Patience, Mhuri, Sarah, Mike, Joice, Ncube, Bekezela, Nderecha, Walter T S, Noah, Munyaradzi, Nyamadzawo, Charles, Penda, Jonathan, Saidi, Asinje, Shonhayi, Sarudzai, Simon, Clemence, Tichagwa, Monica, Chamakono, Rachael, Chauke, Annie, Gatsi, Andrew F, Hwena, Blessing, Jawi, Hillary, Kaisa, Benjamin, Kamutanho, Sithembile, Kaswa, Tapiwa, Kayeruza, Paradhi, Lunga, Juliet, Magogo, Nomatter, Manyeruke, Daniel, Mazani, Patricia, Mhuriyengwe, Fungai, Mlambo, Farisai, Moyo, Stephen, Mpofu, Tawanda, Mugava, Mishelle, Mukungwa, Yvonne, Muroyiwa, Fungai, Mushonga, Eddington, Nyekete, Selestino, Rinashe, Tendai, Sibanda, Kundai, Chemhuru, Milton, Chikunya, Jeffrey, Chikwavaire, Vimbai F, Chikwiriro, Charity, Chimusoro, Anderson, Chinyama, Jotam, Gwinji, Gerald, Hoko-Sibanda, Nokuthula, Kandawasvika, Rutendo, Madzimure, Tendai, Maponga, Brian, Mapuranga, Antonella, Marembo, Joana, Matsunge, Luckmore, Maunga, Simbarashe, Muchekeza, Mary, Muti, Monica, Nyamana, Marvin, Azhuda, Efa, Bhoroma, Urayai, Biriyadi, Ailleen, Chafota, Elizabeth, Chakwizira, Angelline, Chamhamiwa, Agness, Champion, Tavengwa, Chazuza, Stella, Chikwira, Beauty, Chingozho, Chengeto, Chitabwa, Abigail, Dhurumba, Annamary, Furidzirai, Albert, Gandanga, Andrew, Gukuta, Chipo, Macheche, Beauty, Marihwi, Bongani, Masike, Barbara, Mutangandura, Eunice, Mutodza, Beatrice, Mutsindikwa, Angeline, Mwale, Alice, Ndhlovu, Rebecca, Nduna, Norah, Nyamandi, Cathrine, Ruvata, Elias, Sithole, Babra, Urayai, Rofina, Vengesa, Bigboy, Zorounye, Micheal, Bamule, Memory, Bande, Michael, Chahuruva, Kumbirai, Chidumba, Lilian, Chigove, Zvisinei, Chiguri, Kefas, Chikuni, Susan, Chikwanda, Ruvarashe, Chimbi, Tarisai, Chingozho, Micheal, Chinhamo, Olinia, Chinokuramba, Regina, Chinyoka, Chiratidzo, Chipenzi, Xaviour, Chipute, Raviro, Chiribhani, Godfrey, Chitsinga, Mary, Chiwanga, Charles, Chiza, Anamaria, Chombe, Faith, Denhere, Memory, Dhamba, Ephania, Dhamba, Miriam, Dube, Joyas, Dzimbanhete, Florence, Dzingai, Godfrey, Fusira, Sikhutele, Gonese, Major, Gota, Johnson, Gumure, Kresencia, Gwaidza, Phinias, Gwangwava, Margret, Gwara, Winnet, Gwauya, Melania, Gwiba, Maidei, Hamauswa, Joyce, Hlasera, Sarah, Hlukani, Eustina, Hotera, Joseph, Jakwa, Lovemore, Jangara, Gilbert, Janyure, Micheal, Jari, Christopher, Juru, Duvai, Kapuma, Tabeth, Konzai, Paschalina, Mabhodha, Moly, Maburutse, Susan, Macheka, Chipo, Machigaya, Tawanda, Machingauta, Florence, Machokoto, Eucaria, Madhumba, Evelyn, Madziise, Learnard, Madziva, Clipps, Madzivire, Mavis, Mafukise, Mistake, Maganga, Marceline, Maganga, Senzeni, Mageja, Emmanuel, Mahanya, Miriam, Mahaso, Evelyn, Mahleka, Sanelisiwe, Makanhiwa, Pauline, Makarudze, Mavis, Makeche, Constant, Makopa, Nickson, Makumbe, Ranganai, Mandire, Mascline, Mandiyanike, Eunice, Mangena, Eunice, Mangiro, Farai, Mangwadu, Alice, Mangwengwe, Tambudzai, Manhidza, Juliet, Manhovo, Farai, Manono, Irene, Mapako, Shylet, Mapfumo, Evangelista, Mapfumo, Timothy, Mapuka, Jane, Masama, Douglas, Masenge, Getrude, Mashasha, Margreth, Mashivire, Veronica, Matunhu, Moses, Mavhoro, Pazvichaenda, Mawuka, Godfrey, Mazango, Ireen, Mazhata, Netsai, Mazuva, David, Mazuva, Mary, Mbinda, Filomina, Mborera, John, Mfiri, Upenyu, Mhandu, Florence, Mhike, Chrispen, Mhike, Tambudzai, Mhuka, Artwell, Midzi, Judith, Moyo, Siqondeni, Mpundu, Michael, Msekiwa, Nicholas, Msindo, Dominic, Mtisi, Choice, Muchemwa, Gladys, Mujere, Nyadziso, Mukaro, Ellison, Muketiwa, Kilvera, Mungoi, Silvia, Munzava, Esline, Muoki, Rosewita, Mupura, Harugumi, Murerwa, Evelyn, Murisi, Clarieta, Muroyiwa, Letwin, Muruvi, Musara, Musemwa, Nelson, Mushure, Christina, Mutero, Judith, Mutero, Philipa, Mutumbu, Patrick, Mutya, Cleopatra, Muzanango, Lucia, Muzembi, Martin, Muzungunye, Dorcus, Mwazha, Valeliah, Ncube, Thembeni, Ndava, Takunda, Ndlovu, Nomvuyo, Nehowa, Pauline, Ngara, Dorothy, Nguruve, Leonard, Nhigo, Petronella, Nkiwane, Samukeliso, Nyanyai, Luckson, Nzombe, Judith, Office, Evelyn, Paul, Beatrice, Pavari, Shambadzirai, Ranganai, Sylvia, Ratisai, Stella, Rugara, Martha, Rusere, Peter, Sakala, Joyce, Sango, Prosper, Shava, Sibancengani, Shekede, Margaret, Shizha, Cornellious, Sibanda, Tedla, Tapambwa, Neria, Tembo, John, Tinago, Netsai, Tinago, Violet, Toindepi, Theresa, Tovigepi, John, Tuhwe, Modesta, Tumbo, Kundai, Zaranyika, Tinashe, Zaru, Tongai, Zimidzi, Kamurayi, Zindo, Matilda, Zindonda, Maria, Zinhumwe, Nyaradzai, Zishiri, Loveness, Ziyambi, Emerly, Zvinowanda, James, Bepete, Ekenia, Chiwira, Christine, Chuma, Naume, Fari, Abiegirl, Gavi, Samson, Gunha, Violet, Hakunandava, Fadzai, Huku, Constance, Hungwe, Given, Maduke, Grace, Manyewe, Elliot, Mapfumo, Tecla, Marufu, Innocent, Mashiri, Chenesai, Mazenge, Shellie, Mbinda, Euphrasia, Mhuri, Abigail, Muguti, Charity, Munemo, Lucy, Musindo, Loveness, Ngada, Laina, Nyembe, Dambudzo, Taruvinga, Rachel, Tobaiwa, Emma, Banda, Selina, Chaipa, Jesca, Chakaza, Patricia, Chandigere, Macdonald, Changunduma, Annie, Chibi, Chenesai, Chidyagwai, Otilia, Chidza, Elika, Chigatse, Nora, Chikoto, Lennard, Chingware, Vongai, Chinhamo, Jaison, Chinhoro, Marko, Chiripamberi, Answer, Chitavati, Esther, Chitiga, Rita, Chivanga, Nancy, Chivese, Tracy, Chizema, Flora, Dera, Sinikiwe, Dhliwayo, Annacolleta, Dhononga, Pauline, Dimingo, Ennia, Dziyani, Memory, Fambi, Tecla, Gambagamba, Lylian, Gandiyari, Sikangela, Gomo, Charity, Gore, Sarah, Gundani, Jullin, Gundani, Rosemary, Gwarima, Lazarus, Gwaringa, Cathrine, Gwenya, Samuel, Hamilton, Rebecca, Hlabano, Agnes, Hofisi, Ennie, Hofisi, Florence, Hungwe, Stanley, Hwacha, Sharai, Hwara, Aquiiline, Jogwe, Ruth, Kanikani, Atanus, Kuchicha, Lydia, Kutsira, Mitshel, Kuziyamisa, Kumbulani, Kuziyamisa, Mercy, Kwangware, Benjamin, Lozani, Portia, Mabuto, Joseph, Mabuto, Vimbai, Mabvurwa, Loveness, Machacha, Rebecca, Machaya, Cresenzia, Madembo, Roswitha, Madya, Susan, Madzingira, Sheneterai, Mafa, Lloyd, Mafuta, Fungai, Mafuta, Jane, Mahara, Alfred, Mahonye, Sarudzai, Maisva, Admire, Makara, Admire, Makover, Margreth, Mambongo, Ennie, Mambure, Murenga, Mandizvidza, Edith, Mangena, Gladys, Manjengwa, Elliot, Manomano, Julius, Mapfumo, Maria, Mapfurire, Alice, Maphosa, Letwin, Mapundo, Jester, Mare, Dorcas, Marecha, Farai, Marecha, Selina, Mashiri, Christine, Masiya, Medina, Masuku, Thembinkosi, Masvimbo, Priviledge, Matambo, Saliwe, Matarise, Getrude, Matinanga, Loveness, Matizanadzo, John, Maunganidze, Margret, Mawere, Belinda, Mawire, Chipiwa, Mazvanya, Yulliana, Mbasera, Maudy, Mbono, Magret, Mhakayakora, Cynthia, Mhlanga, Nompumelelo, Mhosva, Bester, Moyo, Nomuhle, Moyo, Over, Moyo, Robert, Mpakami, Charity, Mpedzisi, Rudo, Mpofu, Elizabeth, Mpofu, Estery, Mtetwa, Mavis, Muchakachi, Juliet, Mudadada, Tsitsi, Mudzingwa, Kudakwashe, Mugwira, Mejury, Mukarati, Tarsisio, Munana, Anna, Munazo, Juliet, Munyeki, Otilia, Mupfeka, Patience, Murangandi, Gashirai, Muranganwa, Maria, Murenjekwa, Josphine, Muringo, Nothando, Mushaninga, Tichafara, Mutaja, Florence, Mutanha, Dorah, Mutemeri, Peregia, Mutero, Beauty, Muteya, Edina, Muvembi, Sophia, Muzenda, Tandiwe, Mwenjota, Agnes, Ncube, Sithembisiwe, Ndabambi, Tendai, Ndava, Nomsa, Ndlovu, Elija, Nene, Eveln, Ngazimbi, Enniah, Ngwalati, Atalia, Nyama, Tafirenyika, Nzembe, Agnes, Pabwaungana, Eunica, Phiri, Sekai, Pukuta, Ruwiza, Rambanapasi, Melody, Rera, Tambudzai, Samanga, Violet, Shirichena, Sinanzeni, Shoko, Chipiwa, Shonhe, More, Shuro, Cathrine, Sibanda, Juliah, Sibangani, Edna, Sibangani, Nikisi, Sibindi, Norman, Sitotombe, Mercy, Siwawa, Pearson, Tagwirei, Magret, Taruvinga, Pretty, Tavagwisa, Antony, Tete, Esther, Tete, Yeukai, Thandiwe, Elliot, Tibugari, Amonilla, Timothy, Stella, Tongogara, Rumbidzai, Tshuma, Lancy, Tsikira, Mirirayi, Tumba, Constance, Watinaye, Rumbidzayi, Zhiradzango, Ethel, Zimunya, Esther, Zinengwa, Leanmary, Ziupfu, Magret, Ziyambe, Job, Church, James A, Desai, Amy, Fundira, Dadirai, Gough, Ethan, Kambarami, Rukundo A, Matare, Cynthia R, Malaba, Thokozile R, Mupfudze, Tatenda, Ngure, Francis, Smith, Laura E, Curtis, Val, Dickin, Katherine L, Habicht, Jean-Pierre, Masimirembwa, Collen, Morgan, Peter, Pelto, Gretel H, Sheffner-Rogers, Corinne, Thelingwani, Roslyn, Turner, Paul, Zungu, Lindiwe, Makadzange, Tariro, Mujuru, Hilda A, Nyachowe, Chandiwana, Chakadai, Rugare, Chanyau, Gabriel, Makamure, Mary G, Chiwariro, Humphrey, Mtetwa, Tambudzai, Maguwu, Lisbern, Nyadundu, Simon, Moyo, Tshebukani, Chayima, Beauty, Mvindi, Lucy, Rwenhamo, Pauline, Muzvarwandoga, Shamiso, Chimukangara, Rumbidzai, Njovo, Handrea, Makoni, Talent, Majo, Florence, Chasokela, Cynthia M, and Manges, Amee R

Published
2019
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15. Neonatal mortality risk of vulnerable newborns: A descriptive analysis of subnational, population‐based birth cohorts for 238 143 live births in low‐ and middle‐income settings from 2000 to 2017

Author

Hazel, Elizabeth A., primary, Erchick, Daniel J., additional, Katz, Joanne, additional, Lee, Anne C. C., additional, Diaz, Michael, additional, Wu, Lee S. F., additional, West, Keith P., additional, Shamim, Abu Ahmed, additional, Christian, Parul, additional, Ali, Hasmot, additional, Baqui, Abdullah H., additional, Saha, Samir K., additional, Ahmed, Salahuddin, additional, Roy, Arunangshu Dutta, additional, Silveira, Mariângela F., additional, Buffarini, Romina, additional, Shapiro, Roger, additional, Zash, Rebecca, additional, Kolsteren, Patrick, additional, Lachat, Carl, additional, Huybregts, Lieven, additional, Roberfroid, Dominique, additional, Zhu, Zhonghai, additional, Zeng, Lingxia, additional, Gebreyesus, Seifu H., additional, Tesfamariam, Kokeb, additional, Adu‐Afarwuah, Seth, additional, Dewey, Kathryn G., additional, Gyaase, Stephaney, additional, Poku‐Asante, Kwaku, additional, Boamah Kaali, Ellen, additional, Jack, Darby, additional, Ravilla, Thulasiraj, additional, Tielsch, James, additional, Taneja, Sunita, additional, Chowdhury, Ranadip, additional, Ashorn, Per, additional, Maleta, Kenneth, additional, Ashorn, Ulla, additional, Mangani, Charles, additional, Mullany, Luke C., additional, Khatry, Subarna K., additional, Ramokolo, Vundli, additional, Zembe‐Mkabile, Wanga, additional, Fawzi, Wafaie W., additional, Wang, Dongqing, additional, Schmiegelow, Christentze, additional, Minja, Daniel, additional, Msemo, Omari Abdul, additional, Lusingu, John P. A., additional, Smith, Emily R., additional, Masanja, Honorati, additional, Mongkolchati, Aroonsri, additional, Keentupthai, Paniya, additional, Kakuru, Abel, additional, Kajubi, Richard, additional, Semrau, Katherine, additional, Hamer, Davidson H., additional, Manasyan, Albert, additional, Pry, Jake M., additional, Chasekwa, Bernard, additional, Humphrey, Jean, additional, Black, Robert E., additional, Klemm, Rolf D. W., additional, Massie, Allan B., additional, Mitra, Maithilee, additional, Mehra, Sucheta, additional, Schulze, Kerry J., additional, Sommer, Alfred, additional, Ullah, Md. Barkat, additional, Labrique, Alain B., additional, Rashid, Mabhubur, additional, Shaikh, Saijuddin, additional, Begum, Nazma, additional, Chowdhury, Nabidul Haque, additional, Islam, Md. Shafiqul, additional, Khanam, Rasheda, additional, Mitra, Dipak Kumar, additional, Quaiyum, Abdul, additional, Diseko, Modiegi, additional, Makhema, Joseph, additional, Cheng, Yue, additional, Roro, Meselech, additional, Endris, Bilal Shikur, additional, Arnold, Charles D., additional, Bahl, Rajiv, additional, Bhandari, Nita, additional, Martines, Jose, additional, Mazumder, Sarmila, additional, Hallamaa, Lotta, additional, Pyykkö, Juha, additional, Urassa, Willy, additional, Deloron, Phillippe, additional, Bygbjerg, Ib Christian, additional, Moeller, Sofie Lykke, additional, Theander, Thor Grundtvig, additional, Muhihi, Alfa, additional, Noor, Ramadhani Abdallah, additional, Kamya, Moses R., additional, Nakalembe, Miriam, additional, Biemba, Godfrey, additional, Herlihy, Julie M., additional, Mbewe, Reuben K., additional, Mweena, Fern, additional, Yeboah‐Antwi, Kojo, additional, Prendergast, Andrew, additional, Lawn, Joy E., additional, Blencowe, Hannah, additional, Ohuma, Eric, additional, Okwaraji, Yemi, additional, Yargawa, Judith, additional, Bradley, Ellen, additional, and Idueta, Lorena Suarez, additional

Published
2023
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16. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting

Author

Lawn, Joy E, primary, Ohuma, Eric O, additional, Bradley, Ellen, additional, Idueta, Lorena Suárez, additional, Hazel, Elizabeth, additional, Okwaraji, Yemisrach B, additional, Erchick, Daniel J, additional, Yargawa, Judith, additional, Katz, Joanne, additional, Lee, Anne C C, additional, Diaz, Mike, additional, Salasibew, Mihretab, additional, Requejo, Jennifer, additional, Hayashi, Chika, additional, Moller, Ann-Beth, additional, Borghi, Elaine, additional, Black, Robert E, additional, Blencowe, Hannah, additional, Ashorn, Per, additional, Lawn, Joy E, additional, Ashorn, Ulla, additional, Klein, Nigel, additional, Hofmeyr, G Justus, additional, Temmerman, Marleen, additional, Askari, Sufia, additional, Chakwera, Samuel, additional, Hussain-Alkhateeb, Laith, additional, Lewin, Alexandra, additional, Retno Mahanani, Wahyu, additional, White Johansson, Emily, additional, Lavin, Tina, additional, Estevez Fernandez, Diana, additional, Gatica Domínguez, Giovanna, additional, de Costa, Ayesha, additional, Cresswell, Jenny A, additional, Krasevec, Julia, additional, Moran, Allisyn C, additional, Pingray, Veronica, additional, Cormick, Gabriela, additional, Gibbons, Luz, additional, Belizan, José, additional, Guevel, Carlos, additional, Warrilow, Kara, additional, Gordon, Adrienne, additional, Flenady, Vicki, additional, Sexton, Jessica, additional, Lawford, Harriet, additional, Paixao, Enny S., additional, Rocha Falcão, Ila, additional, Lima Barreto, Mauricio, additional, Lisonkova, Sarka, additional, Wen, Qi, additional, Mardones, Francisco, additional, Caulier-Cisterna, Raúl, additional, Acuña, José, additional, Velebil, Petr, additional, Jirova, Jitka, additional, Horváth-Puhó, Erzsébet, additional, Sørensen, Henrik Toft, additional, Sakkeus, Luule, additional, Abuladze, Liili, additional, Gissler, Mika, additional, Moradi-Lakeh, Maziar, additional, Heidarzadeh, Mohammad, additional, Khalili, Narjes, additional, A. Yunis, Khalid, additional, Al Bizri, Ayah, additional, Nakad, Pascale, additional, Devi Karalasingam, Shamala, additional, R Jeganathan, J Ravichandran, additional, binti Baharum, Nurakman, additional, Suárez-Idueta, Lorena, additional, Barranco Flores, Arturo, additional, Gonzalez Roldan, Jesus F, additional, Lopez Alvarez, Sonia, additional, van Dijk, Aimée E., additional, Broeders, Lisa, additional, Huicho, Luis, additional, Quezada Pinedo, Hugo G, additional, Cajachagua-Torres, Kim N, additional, Carrillo-Larco, Rodrigo M, additional, Tarazona Meza, Carla Estefania, additional, Guzman-Vilca, Wilmer Cristobal, additional, Olukade, Tawa O., additional, Ali, Hamdy A., additional, Alyafei, Fawziya, additional, AlQubaisi, Mai, additional, Alturk, Mohamad R, additional, Kim, Ho Yeon, additional, Cho, Geum Joon, additional, Razaz, Neda, additional, Söderling, Jonas, additional, Smith, Lucy K, additional, Kurinczuk, Jennifer J, additional, Matthews, Ruth J, additional, Manktelow, Bradley N, additional, Draper, Elizabeth S, additional, Fenton, Alan C, additional, Lowry, Estelle, additional, Rowland, Neil, additional, Wood, Rachael, additional, Monteath, Kirsten, additional, Pereyra, Isabel, additional, Pravia, Gabriella, additional, Davis, Celina, additional, Clarke, Samantha, additional, Wu, Lee S.F., additional, Yoshida, Sachiyo, additional, Bahl, Rajiv, additional, Grandi, Carlos, additional, Labrique, Alain B, additional, Rashid, Mabhubur, additional, Ahmed, Salahuddin, additional, Roy, Arunangshu D., additional, Haque, Rezwanul, additional, Shaikh, Saijuddin, additional, Baqui, Abdullah H., additional, Saha, Samir K., additional, Khanam, Rasheda, additional, Rahman, Sayedur, additional, Shapiro, Roger, additional, Zash, Rebecca, additional, Silveira, Mariângela F., additional, Buffarini, Romina, additional, Kolsteren, Patrick, additional, Lachat, Carl, additional, Huybregts, Lieven, additional, Roberfroid, Dominique, additional, Zeng, Lingxia, additional, Zhu, Zhonghai, additional, He, Jianrong, additional, Qui, Xiu, additional, Gebreyesus, Seifu H., additional, Tesfamariam, Kokeb, additional, Bekele, Delayehu, additional, Chan, Grace, additional, Baye, Estifanos, additional, Workneh, Firehiwot, additional, Asante, Kwaku P., additional, Boanmah-Kaali, Ellen, additional, Adu-Afarwuah, Seth, additional, Dewey, Kathryn G., additional, Gyaase, Stephaney, additional, Wylie, Blair J., additional, Kirkwood, Betty R., additional, Manu, Alexander, additional, Thulasiraj, Ravilla D, additional, Tielsch, James, additional, Chowdhury, Ranadip, additional, Taneja, Sunita, additional, Babu, Giridhara R, additional, Shriyan, Prafulla, additional, Maleta, Kenneth, additional, Mangani, Charles, additional, Acevedo-Gallegos, Sandra, additional, Rodriguez-Sibaja, Maria J., additional, Khatry, Subarna K., additional, LeClerq, Steven C., additional, Mullany, Luke C., additional, Jehan, Fyezah, additional, Ilyas, Muhammad, additional, Rogerson, Stephen J., additional, Unger, Holger W., additional, Ghosh, Rakesh, additional, Musange, Sabine, additional, Ramokolo, Vundli, additional, Zembe-Mkabile, Wanga, additional, Lazzerini, Marzia, additional, Mohamed, Rishard, additional, Wang, Dongqing, additional, Fawzi, Wafaie W., additional, Minja, Daniel T.R., additional, Schmiegelow, Christentze, additional, Masanja, Honorati, additional, Smith, Emily, additional, Lusingu, John P.A., additional, Msemo, Omari A., additional, Kabole, Fathma M., additional, Slim, Salim N., additional, Keentupthai, Paniya, additional, Mongkolchati, Aroonsri, additional, Kajubi, Richard, additional, Kakuru, Abel, additional, Waiswa, Peter, additional, Walker, Dilys, additional, Hamer, Davidson H., additional, Semrau, Katherine E.A., additional, Chaponda, Enesia B., additional, Chico, R. Matthew, additional, Banda, Bowen, additional, Musokotwane, Kebby, additional, Manasyan, Albert, additional, Pry, Jake M., additional, Chasekwa, Bernard, additional, Humphrey, Jean, additional, Shamim, Abu Ahmed, additional, Christian, Parul, additional, Ali, Hasmot, additional, Klemm, Rolf D.W., additional, Massie, Alan B., additional, Mitra, Maithili, additional, Mehra, Sucheta, additional, Schulze, Kerry J., additional, Shamim, Abu Amed, additional, Sommer, Alfred, additional, Ullah, Barkat, additional, West, Keith P., additional, Begum, Nazma, additional, Chowdhury, Nabidul Haque, additional, Islam, Shafiqul, additional, Mitra, Dipak Kumar, additional, Quaiyum, Abdul, additional, Diseko, Modiegi, additional, Makhema, Joseph, additional, Cheng, Yue, additional, Guo, Yixin, additional, Yuan, Shanshan, additional, Roro, Meselech, additional, Shikur, Bilal, additional, Goddard, Frederick, additional, Haneuse, Sebastien, additional, Hunegnaw, Bezawit, additional, Berhane, Yemane, additional, Worku, Alemayehu, additional, Kaali, Seyram, additional, Arnold, Charles D., additional, Jack, Darby, additional, Amenga-Etego, Seeba, additional, Hurt, Lisa, additional, Shannon, Caitlin, additional, Soremekun, Seyi, additional, Bhandari, Nita, additional, Martines, Jose, additional, Mazumder, Sarmila, additional, Ana, Yamuna, additional, R, Deepa, additional, Hallamaa, Lotta, additional, Pyykkö, Juha, additional, Lumbreras-Marquez, Mario I., additional, Mendoza-Carrera, Claudia E., additional, Hussain, Atiya, additional, Karim, Muhammad, additional, Kausar, Farzana, additional, Mehmood, Usma, additional, Nadeem, Naila, additional, Nisar, Muhammad Imran, additional, Sajid, Muhammad, additional, Mueller, Ivo, additional, Ome-Kaius, Maria, additional, Butrick, Elizabeth, additional, Sayinzoga, Felix, additional, Mariani, Ilaria, additional, Urassa, Willy, additional, Theander, Thor, additional, Deloron, Phillippe, additional, Nielsen, Birgitte Bruun, additional, Muhihi, Alfa, additional, Noor, Ramadhani Abdallah, additional, Bygbjerg, Ib, additional, Moeller, Sofie Lykke, additional, Aftab, Fahad, additional, Ali, Said M., additional, Dhingra, Pratibha, additional, Dhingra, Usha, additional, Dutta, Arup, additional, Sazawal, Sunil, additional, Suleiman, Atifa, additional, Mohammed, Mohammed, additional, Deb, Saikat, additional, Kamya, Moses R., additional, Nakalembe, Miriam, additional, Mulowooz, Jude, additional, Santos, Nicole, additional, Biemba, Godfrey, additional, Herlihy, Julie M., additional, Mbewe, Reuben K., additional, Mweena, Fern, additional, Yeboah-Antwi, Kojo, additional, Bruce, Jane, additional, Chandramohan, Daniel, additional, and Prendergast, Andrew, additional

Published
2023
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18. Enteropathogens and Rotavirus Vaccine Immunogenicity in a Cluster Randomized Trial of Improved Water, Sanitation and Hygiene in Rural Zimbabwe

Author

Church, James A., Rogawski McQuade, Elizabeth T., Mutasa, Kuda, Taniuchi, Mami, Rukobo, Sandra, Govha, Margaret, Lee, Benjamin, Carmolli, Marya P., Chasekwa, Bernard, Ntozini, Robert, McNeal, Monica M., Moulton, Lawrence H., Kirkpatrick, Beth D., Liu, Jie, Houpt, Eric R., Humphrey, Jean H., Platts-Mills, James A., and Prendergast, Andrew J.

Published
2019
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19. Fat and lean mass predict time to hospital readmission or mortality in children treated for complicated severe acute malnutrition in Zimbabwe and Zambia.

Author

Bwakura-Dangarembizi, Mutsa, Dumbura, Cherlynn, Ngosa, Deophine, Majo, Florence D., Piper, Joe D., Sturgeon, Jonathan P., Nathoo, Kusum J., Amadi, Beatrice, Norris, Shane, Chasekwa, Bernard, Ntozini, Robert, Wells, Jonathan C., Kelly, Paul, and Prendergast, Andrew J.

Subjects
HIV infection complications, MALNUTRITION treatment, BODY composition, HOSPITALS, SKINFOLD thickness, CONFIDENCE intervals, TIME, LEAN body mass, PATIENT readmissions, RISK assessment, MALNUTRITION, BIOELECTRIC impedance, WASTING syndrome, RESEARCH funding, STATISTICAL models, CHILD mortality, ADIPOSE tissues, PROPORTIONAL hazards models, DISCHARGE planning, EDEMA, DISEASE complications
Abstract

HIV and severe wasting are associated with post-discharge mortality and hospital readmission among children with complicated severe acute malnutrition (SAM); however, the reasons remain unclear. We assessed body composition at hospital discharge, stratified by HIV and oedema status, in a cohort of children with complicated SAM in three hospitals in Zambia and Zimbabwe. We measured skinfold thicknesses and bioelectrical impedance analysis (BIA) to investigate whether fat and lean mass were independent predictors of time to death or readmission. Cox proportional hazards models were used to estimate the association between death/readmission and discharge body composition. Mixed effects models were fitted to compare longitudinal changes in body composition over 1 year. At discharge, 284 and 546 children had complete BIA and skinfold measurements, respectively. Low discharge lean and peripheral fat mass were independently associated with death/hospital readmission. Each unit Z -score increase in impedance index and triceps skinfolds was associated with 48 % (adjusted hazard ratio 0·52, 95 % CI (0·30, 0·90)) and 17 % (adjusted hazard ratio 0·83, 95 % CI (0·71, 0·96)) lower hazard of death/readmission, respectively. HIV-positive v. HIV-negative children had lower gains in sum of skinfolds (mean difference −1·49, 95 % CI (−2·01, −0·97)) and impedance index Z -scores (–0·13, 95 % CI (−0·24, −0·01)) over 52 weeks. Children with non-oedematous v. oedematous SAM had lower mean changes in the sum of skinfolds (–1·47, 95 % CI (−1·97, −0·97)) and impedance index Z -scores (–0·23, 95 % CI (−0·36, −0·09)). Risk stratification to identify children at risk for mortality or readmission, and interventions to increase lean and peripheral fat mass, should be considered in the post-discharge care of these children. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Child Health, Agriculture and Integrated Nutrition (CHAIN): protocol for a randomised controlled trial of improved infant and young child feeding in rural Zimbabwe

Author

Smith, Laura E, primary, Chagwena, Dexter. T, additional, Bourke, Claire, additional, Robertson, Ruairi, additional, Fernando, Shamiso, additional, Tavengwa, Naume V, additional, Cairns, Jill, additional, Ndhlela, Thokozile, additional, Matumbu, Exhibit, additional, Brown, Tim, additional, Datta, Kavita, additional, Mutasa, Batsirai, additional, Tengende, Alice, additional, Chidhanguro, Dzivaidzo, additional, Langhaug, Lisa, additional, Makanza, Maggie, additional, Chasekwa, Bernard, additional, Mutasa, Kuda, additional, Swann, Jonathan, additional, Kelly, Paul, additional, Ntozini, Robert, additional, and Prendergast, Andrew, additional

Published
2022
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24. 759 The association between maternal-child interaction, maternal depression and early child development: an observational sub-study in rural Zimbabwe

Author

Ooi, Yujing, primary, Chandna, Jaya, additional, Majo, Florence, additional, Tavengwa, Naume, additional, Mutasa, Batsirai, additional, Kandawakviska, Gwendoline, additional, Chasekwa, Bernard, additional, Humphrey, Jean, additional, Ntozini, Robert, additional, Prendergast, Andrew, additional, and Gladstone, Melissa, additional

Published
2022
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25. Stunting Status and Exposure to Infection and Inflammation in Early Life Shape Antibacterial Immune Cell Function Among Zimbabwean Children

Author

Mutasa, Kuda, primary, Tome, Joice, additional, Rukobo, Sandra, additional, Govha, Margaret, additional, Mushayanembwa, Patience, additional, Matimba, Farai S., additional, Chiorera, Courage K., additional, Majo, Florence D., additional, Tavengwa, Naume V., additional, Mutasa, Batsirai, additional, Chasekwa, Bernard, additional, Humphrey, Jean H., additional, Ntozini, Robert, additional, Prendergast, Andrew J., additional, and Bourke, Claire D., additional

Published
2022
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26. Additional file 1 of Implementation and maintenance of infant dietary diversity in Zimbabwe: contribution of food and water insecurity

Author

Koyratty, Nadia, Mbuya, Mduduzi N. N., Jones, Andrew D., Schuster, Roseanne C., Kordas, Katarzyna, Li, Chin-Shang, Tavengwa, Naume V., Majo, Florence D., Chasekwa, Bernard, Ntozini, Robert, Humphrey, Jean H., and Smith, Laura E.

Abstract

Additional file 1: Table S1. Sensitivity analyses of the association between implementation of minimum infant dietary diversity at 12 months and household-level multidimensional food insecurity and water insecurity. Table S2. Sensitivity analyses of associations of minimum infant dietary diversity maintenance from 12 to 18 months and multidimensional household-level food insecurity and water insecurity.

Published
2022
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27. Recovery of children following hospitalisation for complicated severe acute malnutrition

Author

Bwakura‐Dangarembizi, Mutsa, primary, Dumbura, Cherlynn, additional, Amadi, Beatrice, additional, Chasekwa, Bernard, additional, Ngosa, Deophine, additional, Majo, Florence D., additional, Sturgeon, Jonathan P., additional, Chandwe, Kanta, additional, Kapoma, Chanda, additional, Bourke, Claire D., additional, Robertson, Ruairi C., additional, Nathoo, Kusum J., additional, Ntozini, Robert, additional, Norris, Shane A., additional, Kelly, Paul, additional, and Prendergast, Andrew J., additional

Published
2021
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29. Prevalence, risk factors and short-term consequences of adverse birth outcomes in Zimbabwean pregnant women: a secondary analysis of a cluster-randomized trial.

Author

Chasekwa, Bernard, Ntozini, Robert, Church, James A, Majo, Florence D, Tavengwa, Naume, Mutasa, Batsirai, Noble, Christie, Koyratty, Nadia, Maluccio, John A, Prendergast, Andrew J, Humphrey, Jean H, Smith, Laura E, and Team, for the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial

Subjects
*NEONATAL death, *PREGNANT women, *PREMATURE infants, *NEONATAL mortality, *PERINATAL death, *SMALL for gestational age
Abstract

Background Globally, 15 million children are born preterm each year and 10.7 million are born at term but with low birthweight (<2500 g). Methods The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) cluster-randomized trial enrolled 5280 pregnant women between 22 November 2012 and 27 March 2015 to test the impact of improved water supply, sanitation and hygiene, and improved infant feeding, on child growth and anaemia. We conducted a secondary analysis to estimate the prevalence and risk factors of miscarriage, stillbirth, preterm birth, size small for gestational age (SGA), low birthweight (LBW), perinatal mortality, and neonatal mortality, and to estimate the effects of adverse birth outcomes on infant survival and growth.  Results The prevalence of adverse birth outcomes was: miscarriage: 5.0% [95% confidence interval (CI), 4.4, 5.7]; stillbirth: 2.3% (95% CI 1.9, 2.7); preterm birth: 18.2% (95% CI 16.9, 19.5); SGA: 16.1% (95% CI 15.0, 17.3); LBW: 9.8% (95% CI 9.0, 10.7); and neonatal mortality: 31.4/1000 live births (95% CI 26.7, 36.5). Modifiable risk factors included maternal HIV infection, anaemia, lack of antenatal care and non-institutional delivery. Preterm infants had higher neonatal mortality [risk ratio (RR): 6.1 (95% CI 4.0, 9.2)], post-neonatal infant mortality [hazard ratio (HR): 2.1 (95% CI 1.1, 4.1)] and stunting at 18 months of age [RR: 1.5 (95% CI 1.4, 1.7)] than term infants; 56% of stillbirths and 57% of neonatal deaths were among preterm births.  Conclusions Neonatal mortality and stillbirth are high in Zimbabwe and appear to be driven by high preterm birth. Interventions for primary prevention of preterm birth and strengthened management of preterm labour and ill and small neonates are required to reduce neonatal mortality in Zimbabwe and other African countries with similar profiles. [ABSTRACT FROM AUTHOR]

Published
2022
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30. The fecal microbiome and rotavirus vaccine immunogenicity in rural Zimbabwean infants

Author

Robertson, Ruairi C., primary, Church, James A., additional, Edens, Thaddeus J., additional, Mutasa, Kuda, additional, Min Geum, Hyun, additional, Baharmand, Iman, additional, Gill, Sandeep K., additional, Ntozini, Robert, additional, Chasekwa, Bernard, additional, Carr, Lynnea, additional, Majo, Florence D., additional, Kirkpatrick, Beth D., additional, Lee, Benjamin, additional, Moulton, Lawrence H., additional, Humphrey, Jean H., additional, Prendergast, Andrew J., additional, and Manges, Amee R., additional

Published
2021
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31. The Impact of Improved Water, Sanitation, and Hygiene on Oral Rotavirus Vaccine Immunogenicity in Zimbabwean Infants: Substudy of a Cluster-randomized Trial

Author

Church, James A, Rukobo, Sandra, Govha, Margaret, Lee, Benjamin, Carmolli, Marya P, Chasekwa, Bernard, Ntozini, Robert, Mutasa, Kuda, McNeal, Monica M, Majo, Florence D, Tavengwa, Naume V, Moulton, Lawrence H, Humphrey, Jean H, Kirkpatrick, Beth D, and Prendergast, Andrew J

Subjects
Male, Rotavirus, Zimbabwe, infants, Vaccination, Rotavirus Vaccines, Hygiene, Rotavirus Infections, WASH, Immunogenicity, Vaccine, Pregnancy, Water Quality, Africa, Humans, Female, Sanitation, oral vaccine, Articles and Commentaries
Abstract

Background Oral vaccines have lower efficacy in developing compared to developed countries. Poor water, sanitation, and hygiene (WASH) may contribute to reduced oral vaccine immunogenicity. Methods We conducted a cluster-randomized 2 × 2 factorial trial in rural Zimbabwe. Pregnant women and their infants were eligible if they lived in clusters randomized to (1) standard of care (52 clusters); (2) improved infant feeding (53 clusters); (3) WASH: ventilated improved pit latrine, 2 hand-washing stations, liquid soap, chlorine, infant play space, and hygiene counseling (53 clusters); or (4) feeding plus WASH (53 clusters). This substudy compared oral rotavirus vaccine (RVV) seroconversion (primary outcome), and seropositivity and geometric mean titer (GMT) (secondary outcomes), in WASH vs non-WASH infants by intention-to-treat analysis. Results We included 801 infants with documented RVV receipt and postvaccine titer measurements (329 from 84 WASH clusters; 472 from 102 non-WASH clusters); 328 infants with prevaccination titers were included in the primary outcome. Thirty-three of 109 (30.3%) infants in the WASH group seroconverted following rotavirus vaccination, compared to 43 of 219 (19.6%) in the non-WASH group (absolute difference, 10.6% [95% confidence interval {CI}, .54%–20.7%]; P = .031). In the WASH vs non-WASH groups, 90 of 329 (27.4%) vs 107 of 472 (22.7%) were seropositive postvaccination (absolute difference, 4.7% [95% CI, –1.4% to 10.8%]; P = .130), and antirotavirus GMT was 18.4 (95% CI, 15.6–21.7) U/mL vs 14.9 (95% CI, 13.2–16.8) U/mL (P = .072). Conclusions Improvements in household WASH led to modest but significant increases in seroconversion to RVV in rural Zimbabwean infants. Clinical Trials Registration NCT01824940., Oral vaccines have lower efficacy in developing compared to developed countries. In a substudy of a cluster-randomized trial, improvements in household water, sanitation, and hygiene led to modest increases in seroconversion to oral rotavirus vaccine among rural Zimbabwean infants.

Published
2019

32. Maternal fecal microbiome predicts gestational age, birth weight and neonatal growth in rural Zimbabwe.

Author

Gough, Ethan K., primary, Edens, Thaddeus J., additional, Geum, Hyun Min, additional, Baharmand, Iman, additional, Gill, Sandeep K., additional, Robertson, Ruairi C., additional, Mutasa, Kuda, additional, Ntozini, Robert, additional, Smith, Laura E, additional, Chasekwa, Bernard, additional, Majo, Florence D., additional, Tavengwa, Naume V., additional, Mutasa, Batsirai, additional, Francis, Freddy, additional, Carr, Lynnea, additional, Tome, Joice, additional, Stoltzfus, Rebecca J., additional, Moulton, Lawrence H., additional, Prendergast, Andrew J., additional, Humphrey, Jean H., additional, Manges, Amee R., additional, and Team, SHINE Trial, additional

Published
2021
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35. Recovery of children following hospitalisation for complicated severe acute malnutrition.

Author

Bwakura‐Dangarembizi, Mutsa, Dumbura, Cherlynn, Amadi, Beatrice, Chasekwa, Bernard, Ngosa, Deophine, Majo, Florence D., Sturgeon, Jonathan P., Chandwe, Kanta, Kapoma, Chanda, Bourke, Claire D., Robertson, Ruairi C., Nathoo, Kusum J., Ntozini, Robert, Norris, Shane A., Kelly, Paul, and Prendergast, Andrew J.

Subjects
MALNUTRITION treatment, STATURE, HIV infections, CONFIDENCE intervals, NUTRITIONAL assessment, CONVALESCENCE, ANTHROPOMETRY, PATIENT readmissions, REGRESSION analysis, FISHER exact test, MANN Whitney U Test, DISEASES, TREATMENT effectiveness, DESCRIPTIVE statistics, CHI-squared test, DATA analysis software, CEREBRAL palsy, HOSPITAL care of children, SECONDARY analysis, PROPORTIONAL hazards models, EVALUATION, CHILDREN
Abstract

Nutritional recovery and hospital readmission following inpatient management of complicated severe acute malnutrition (SAM) are poorly characterised. We aimed to ascertain patterns and factors associated with hospital readmission, nutritional recovery and morbidity, in children discharged from hospital following management of complicated SAM in Zambia and Zimbabwe over 52‐weeks posthospitalization. Multivariable Fine‐Gray subdistribution hazard models, with death and loss to follow‐up as competing risks, were used to identify factors associated with hospital readmission; negative binomial regression to assess time to hospitalisation and ordinal logistic regression to model factors associated with nutritional recovery. A total of 649 children (53% male, median age 18.2 months) were discharged to continue community nutritional rehabilitation. All‐cause hospital readmission was 15.4% (95% CI 12.7, 18.6) over 52 weeks. Independent risk factors for time to readmission were cerebral palsy (adjusted subhazard ratio (aSHR): 2.96, 95% CI 1.56, 5.61) and nonoedematous SAM (aSHR: 1.64, 95%CI 1.03, 2.64). Unit increases in height‐for‐age Z‐score (HAZ) (aSHR: 0.82, 95% CI 0.71, 0.95) and enrolment in Zambia (aSHR: 0.52, 95% CI 0.28, 0.97) were associated with reduced subhazard of time to readmission. Young age, SAM at discharge, nonoedematous SAM and cerebral palsy were associated with poor nutritional recovery throughout follow‐up. Collectively, nonoedematous SAM, ongoing SAM at discharge, cerebral palsy and low HAZ are independent risk factors for readmission and poor nutritional recovery following complicated SAM. Children with these high‐risk features should be prioritised for additional convalescent care to improve long‐term outcomes. Key messages: One‐in‐six children managed for SAM were readmitted into hospital over the first year after discharge and one‐in‐eight remained undernourished by 52 weeks of follow‐up.Nonoedematous SAM, ongoing SAM at the time of discharge and underlying cerebral palsy were independent risk factors for hospital readmission and poor nutritional recovery.Low HAZ was a risk factor for hospital readmission and poor nutritional recovery.Postdischarge care should focus on children with disability, nonoedematous SAM at initial hospitalisation and have ongoing SAM at the time of discharge.Stunting should be considered in the management of children with SAM. [ABSTRACT FROM AUTHOR]

Published
2022
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36. Risk factors for postdischarge mortality following hospitalization for severe acute malnutrition in Zimbabwe and Zambia

Author

Bwakura-Dangarembizi, Mutsa, primary, Dumbura, Cherlynn, additional, Amadi, Beatrice, additional, Ngosa, Deophine, additional, Majo, Florence D, additional, Nathoo, Kusum J, additional, Mwakamui, Simutanyi, additional, Mutasa, Kuda, additional, Chasekwa, Bernard, additional, Ntozini, Robert, additional, Kelly, Paul, additional, and Prendergast, Andrew J, additional

Published
2021
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38. The Friendship Bench as a brief psychological intervention with peer support in rural Zimbabwean women: a mixed methods pilot evaluation

Author

Fernando, Shamiso, primary, Brown, Tim, additional, Datta, Kavita, additional, Chidhanguro, Dzivaidzo, additional, Tavengwa, Naume V., additional, Chandna, Jaya, additional, Munetsi, Epiphania, additional, Dzapasi, Lloyd, additional, Nyachowe, Chandiwana, additional, Mutasa, Batsirai, additional, Chasekwa, Bernard, additional, Ntozini, Robert, additional, Chibanda, Dixon, additional, and Prendergast, Andrew J., additional

Published
2021
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39. Associations Between Biomarkers of Environmental Enteric Dysfunction and Oral Rotavirus Vaccine Immunogenicity in Rural Zimbabwean Infants

Author

Church, James, primary, Rukobo, Sandra, additional, Govha, Margaret, additional, Gough, Ethan, additional, Chasekwa, Bernard, additional, Lee, Benjamin, additional, Carmolli, Marya, additional, Panic, Gordana, additional, Giallourou, Natasa, additional, Ntozini, Robert, additional, Mutasa, Kuda, additional, McNeal, Monica, additional, Majo, Florence, additional, Tavengwa, Naume, additional, Swann, Jonathan, additional, Moulton, Lawrence H., additional, Kirkpatrick, Beth D., additional, Humphrey, Jean, additional, and Prendergast, Andrew, additional

Published
2021
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40. Predictors of oral rotavirus vaccine immunogenicity in rural Zimbabwean infants

Author

Church, James A., primary, Chasekwa, Bernard, additional, Rukobo, Sandra, additional, Govha, Margaret, additional, Lee, Benjamin, additional, Carmolli, Marya P., additional, Ntozini, Robert, additional, Mutasa, Kuda, additional, McNeal, Monica M., additional, Majo, Florence D., additional, Tavengwa, Naume V., additional, Kirkpatrick, Beth D., additional, Moulton, Lawrence H., additional, Humphrey, Jean H., additional, and Prendergast, Andrew J., additional

Published
2020
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41. Effects of improved complementary feeding and improved water, sanitation and hygiene on early child development among HIV-exposed children: substudy of a cluster randomised trial in rural Zimbabwe

Author

Chandna, Jaya, primary, Ntozini, Robert, additional, Evans, Ceri, additional, Kandawasvika, Gwendoline, additional, Chasekwa, Bernard, additional, Majo, Florence D, additional, Mutasa, Kuda, additional, Tavengwa, Naume V, additional, Mutasa, Batsirai, additional, NN Mbuya, Mduduzi, additional, Moulton, Lawrence H, additional, Humphrey, Jean H, additional, Prendergast, Andrew J, additional, and Gladstone, Melissa, additional

Published
2020
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42. Determinants of Urogenital Schistosomiasis Among Pregnant Women and its Association With Pregnancy Outcomes, Neonatal Deaths, and Child Growth

Author

Murenjekwa, Wellington, primary, Makasi, Rachel, additional, Ntozini, Robert, additional, Chasekwa, Bernard, additional, Mutasa, Kuda, additional, Moulton, Lawrence H, additional, Tielsch, James M, additional, Humphrey, Jean H, additional, Smith, Laura E, additional, Prendergast, Andrew J, additional, and Bourke, Claire D, additional

Published
2019
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43. Early Initiation and Exclusivity of Breastfeeding in Rural Zimbabwe: Impact of a Breastfeeding Intervention Delivered by Village Health Workers

Author

Mbuya, Mduduzi N N, Matare, Cynthia R, Tavengwa, Naume V, Chasekwa, Bernard, Ntozini, Robert, Majo, Florence D, Chigumira, Ancikaria, Chasokela, Cynthia M Z, Prendergast, Andrew J, Moulton, Lawrence H, Stoltzfus, Rebecca J, and Humphrey, Jean H

Subjects
Zimbabwe, early breastfeeding initiation, village health workers, infants, Maternal and Pediatric Nutrition, exclusive breastfeeding, breast milk, Original Research
Abstract

Background Suboptimal breastfeeding contributes to >800,000 global child deaths annually. Optimal breastfeeding includes early initiation (EI) and exclusive breastfeeding (EBF) for the first 6 mo. Objectives We tested the hypothesis that an intervention targeting context and infant age-specific barriers to EI and EBF will achieve a higher EI and EBF prevalence than those of women participating in the concurrently conducted 2015 Zimbabwe Demographic Health Survey (Z-DHS). Methods We designed an intervention to promote EI and EBF, and implemented it within the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial in rural Zimbabwe. Intervention modules were delivered at 4 perinatal time points by government-employed village health workers. We compared EI and EBF prevalence among SHINE women who provided outcomes at 1 mo (n = 2442) and 3 mo (n = 2728), with women in the 2015 Z-DHS. Results In cross-sectional analyses EI prevalence was 86.6% and 64.3% in the SHINE and Z-DHS samples, respectively; absolute difference (95% CI) = 22.4% (17.5%, 27.3%). EBF prevalence was similarly high (>80%) in both surveys during the first month of life; during 1 to

Published
2019

44. Determinants of Urogenital Schistosomiasis Among Pregnant Women and its Association With Pregnancy Outcomes, Neonatal Deaths, and Child Growth.

Author

Murenjekwa, Wellington, Makasi, Rachel, Ntozini, Robert, Chasekwa, Bernard, Mutasa, Kuda, Moulton, Lawrence H, Tielsch, James M, Humphrey, Jean H, Smith, Laura E, Prendergast, Andrew J, Bourke, Claire D, and SHINE Trial Team

Subjects
PREGNANCY outcomes, PREGNANT women, NEONATAL death, GROWTH of children, SCHISTOSOMIASIS, RESEARCH, TREMATODA, CHILD development, ANIMAL experimentation, MICROSCOPY, RESEARCH methodology, EVALUATION research, PERINATAL death, COMPARATIVE studies, BIRTH weight, RESEARCH funding, HEMATURIA, URINALYSIS, PARASITIC diseases in pregnancy, DISEASE complications
Abstract

Background: Schistosoma haematobium is a parasitic helminth that causes urogenital pathology. The impact of urogenital schistosomiasis during pregnancy on birth outcomes and child growth is poorly understood.Methods: Risk factors for urogenital schistosomiasis were characterized among 4437 pregnant women enrolled in a cluster-randomized community-based trial in rural Zimbabwe. Infection was defined via urine microscopy (≥1 S. haematobium egg) and urinalysis (hematuria). Associations between infection and pregnancy outcomes were assessed in case-control analyses using conditional logistic regression. The association of maternal infection with birthweight and length-for-age Z scores (LAZ) at 1 and 18 months of age were assessed using generalized estimating equations.Results: Urogenital schistosomiasis (egg positive and/or hematuria positive) was detected in 26.8% of pregnant women. Risk factors significantly associated with infection were maternal age, education, marital status, and religion; household drinking water source and latrine; study region; and season. Urogenital schistosomiasis was not significantly associated with adverse pregnancy outcomes (miscarriage, stillbirth, preterm, and small-for-gestational age), birthweight, neonatal death, or LAZ.Conclusions: Including pregnant women in antihelminthic treatment programs would benefit a large number of women in rural Zimbabwe. However, clearance of the low-intensity infections that predominate in this context is unlikely to have additive benefits for pregnancy outcomes or child growth.Clinical Trials Registration: NCT01824940. [ABSTRACT FROM AUTHOR]

Published
2021
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45. Measuring wealth in rural communities: Lessons from the Sanitation, Hygiene, Infant Nutrition Efficacy (SHINE) trial

Author

Chasekwa, Bernard, Maluccio, John A, Ntozini, Robert, Moulton, Lawrence H, Wu, Fan, Smith, Laura E, Matare, Cynthia R, Stoltzfus, Rebecca J, Mbuya, Mduduzi NN, Tielsch, James M, Martin, Stephanie L, Jones, Andrew D, Humphrey, Jean H, Fielding, Katherine, and SHINE Trial Team

Subjects
lcsh:R, lcsh:Medicine, lcsh:Q, lcsh:Science
Abstract

BACKGROUND: Poverty and human capital development are inextricably linked and therefore research on human capital typically incorporates measures of economic well-being. In the context of randomized trials of health interventions, for example, such measures are used to: 1) assess baseline balance; 2) estimate covariate-adjusted analyses; and 3) conduct subgroup analyses. Many factors characterize economic well-being, however, and analysts often generate summary measures such as indices of household socio-economic status or wealth. In this paper, a household wealth index is developed and tested for participants in the cluster-randomized Sanitation, Hygiene, Infant Nutrition Efficacy (SHINE) trial in rural Zimbabwe. METHODS: Building on the approach used in the Zimbabwe Demographic and Health Survey (ZDHS), we combined a set of housing characteristics, ownership of assets and agricultural resources into a wealth index using principal component analysis (PCA) on binary variables. The index was assessed for internal and external validity. Its sensitivity was examined considering an expanded set of variables and an alternative statistical approach of polychoric PCA. Correlation between indices was determined using the Spearman's rank correlation coefficient and agreement between quintiles using a linear weighted Kappa statistic. Using the 2015 ZDHS data, we constructed a separate index and applied the loadings resulting from that analysis to the SHINE study population, to compare the wealth distribution in the SHINE study with rural Zimbabwe. RESULTS: The derived indices using the different methods were highly correlated (r>0.9), and the wealth quintiles derived from the different indices had substantial to near perfect agreement (linear weighted Kappa>0.7). The indices were strongly associated with a range of assets and other wealth measures, indicating both internal and external validity. Households in SHINE were modestly wealthier than the overall population of households in rural Zimbabwe. CONCLUSION: The SHINE wealth index developed here is a valid and robust measure of wealth in the sample.

Published
2018

46. Putting the “A” into WaSH: a call for integrated management of water, animals, sanitation, and hygiene

Author

Prendergast, Andrew J, primary, Gharpure, Radhika, additional, Mor, Siobhan, additional, Viney, Mark, additional, Dube, Kululeko, additional, Lello, Joanne, additional, Berger, Cedric, additional, Siwila, Joyce, additional, Joyeux, Mathieu, additional, Hodobo, Tinashe, additional, Hurt, Lisa, additional, Brown, Tim, additional, Hoto, Patience, additional, Tavengwa, Naume, additional, Mutasa, Kuda, additional, Craddock, Susan, additional, Chasekwa, Bernard, additional, Robertson, Ruairi C, additional, Evans, Ceri, additional, Chidhanguro, Dzivaidzo, additional, Mutasa, Batsirai, additional, Majo, Florence, additional, Smith, Laura E, additional, Hirai, Mitsuaki, additional, Ntozini, Robert, additional, Humphrey, Jean H, additional, and Berendes, David, additional

Published
2019
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47. Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on stunting and anaemia among HIV-exposed children in rural Zimbabwe: a cluster-randomised controlled trial

Author

Prendergast, Andrew J, primary, Chasekwa, Bernard, additional, Evans, Ceri, additional, Mutasa, Kuda, additional, Mbuya, Mduduzi N N, additional, Stoltzfus, Rebecca J, additional, Smith, Laura E, additional, Majo, Florence D, additional, Tavengwa, Naume V, additional, Mutasa, Batsirai, additional, Mangwadu, Goldberg T, additional, Chasokela, Cynthia M, additional, Chigumira, Ancikaria, additional, Moulton, Lawrence H, additional, Ntozini, Robert, additional, and Humphrey, Jean H, additional

Published
2019
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49. Mortality, Human Immunodeficiency Virus (HIV) Transmission, and Growth in Children Exposed to HIV in Rural Zimbabwe.

Author

Evans, Ceri, Chasekwa, Bernard, Ntozini, Robert, Majo, Florence D, Mutasa, Kuda, Tavengwa, Naume, Mutasa, Batsirai, Mbuya, Mduduzi N N, Smith, Laura E, Stoltzfus, Rebecca J, Moulton, Lawrence H, Humphrey, Jean H, Prendergast, Andrew J, and Team, for the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial

Subjects
*HIV prevention, *HIV infection transmission, *ANTHROPOMETRY, *COMPARATIVE studies, *CONFIDENCE intervals, *GROWTH disorders, *HIV, *HIV infections, *HIV-positive persons, *HUMAN growth, *INFANT mortality, *MEDICAL screening, *MOTHERS, *RURAL conditions, *ANTIRETROVIRAL agents, *VERTICAL transmission (Communicable diseases), *DESCRIPTIVE statistics, *CHILDREN, *FETUS
Abstract

Background Clinical outcomes of children who are human immunodeficiency virus (HIV)–exposed in sub-Saharan Africa remain uncertain. Methods The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial evaluated improved infant and young child feeding (IYCF) and/or improved water, sanitation, and hygiene in 2 rural Zimbabwean districts with 15% antenatal HIV prevalence and > 80% prevention of mother-to-child transmission (PMTCT) coverage. Children born between February 2013 and December 2015 had longitudinal HIV testing and anthropometry. We compared mortality and growth between children who were HIV-exposed and HIV-unexposed through 18 months. Children receiving IYCF were excluded from growth analyses. Results Fifty-one of 738 (7%) children who were HIV-exposed and 198 of 3989 (5%) children who were HIV-unexposed (CHU) died (hazard ratio, 1.41 [95% confidence interval {CI}, 1.02–1.93]). Twenty-five (3%) children who were HIV-exposed tested HIV positive, 596 (81%) were HIV-exposed uninfected (CHEU), and 117 (16%) had unknown HIV status by 18 months; overall transmission estimates were 4.3%–7.7%. Mean length-for-age z score at 18 months was 0.38 (95% CI,.24–.51) standard deviations lower among CHEU compared to CHU. Among 367 children exposed to HIV in non-IYCF arms, 147 (40%) were alive, HIV-free, and nonstunted at 18 months, compared to 1169 of 1956 (60%) CHU (absolute difference, 20% [95% CI, 15%–26%]). Conclusions In rural Zimbabwe, mortality remains 40% higher among children exposed to HIV, vertical transmission exceeds elimination targets, and half of CHEU are stunted. We propose the composite outcome of "alive, HIV free, and thriving" as the long-term goal of PMTCT programs. Clinical Trials Registration NCT01824940. [ABSTRACT FROM AUTHOR]

Published
2021
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50. The Friendship Bench as a brief psychological intervention with peer support in rural Zimbabwean women: a mixed methods pilot evaluation.

Author

Fernando, Shamiso, Brown, Tim, Datta, Kavita, Chidhanguro, Dzivaidzo, Tavengwa, Naume V., Chandna, Jaya, Munetsi, Epiphania, Dzapasi, Lloyd, Nyachowe, Chandiwana, Mutasa, Batsirai, Chasekwa, Bernard, Ntozini, Robert, Chibanda, Dixon, and Prendergast, Andrew J.

Subjects
PSYCHOTHERAPY, RURAL women, PROBLEM-solving therapy, EDINBURGH Postnatal Depression Scale, COMMUNITY health workers
Abstract

Background: There is a large treatment gap for common mental disorders in rural areas of low-income countries. We tested the Friendship Bench as a brief psychological intervention delivered by village health workers (VHWs) in rural Zimbabwe. Methods: Rural women identified with depression in a previous trial received weekly home-based problem-solving therapy from VHWs for 6 weeks, and joined a peer-support group. Depression was assessed using the Edinburgh Postnatal Depression Scale (EPDS) and Shona Symptom Questionnaire (SSQ). Acceptability was explored through in-depth interviews and focus group discussions. The proportion of women with depression pre- and post-intervention was compared using McNemar's test. Results: Ten VHWs delivered problem-solving therapy to 27 women of mean age 33 years; 25 completed six sessions. Women valued an established and trustful relationship with their VHW, which ensured confidentiality and prevented gossip, and reported finding individual problem-solving therapy beneficial. Peer-support meetings provided space to share problems, solutions and skills. The proportion of women with depression or suicidal ideation on the EPDS declined from 68% to 12% [difference 56% (95% confidence interval (CI) 27.0–85.0); p = 0.001], and the proportion scoring high (>7) on the SSQ declined from 52% to 4% [difference 48% (95% CI 24.4–71.6); p < 0.001] after the 6-week intervention. Conclusion: VHW-delivered problem-solving therapy and peer-support was acceptable and showed promising results in this pilot evaluation, leading to quantitative and qualitative improvements in mental health among rural Zimbabwean women. Scale-up of the Friendship Bench in rural areas would help close the treatment gap for common mental disorders. [ABSTRACT FROM AUTHOR]

Published
2021
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