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329 results on '"Chen, Amy Y"'

5. Prognostic biomarkers in patients with human immunodeficiency virus‐positive disease with head and neck squamous cell carcinoma

Author

Zhang, Hongzheng, Kim, Sungjin, Chen, Zhengjia, Nannapaneni, Sreenivas, Chen, Amy Y, Moore, Charles E, Sica, Gabriel, Mosunjac, Marina, Nguyen, Minh Ly T, D'Souza, Gypsyamber, Carey, Thomas E, Peterson, Lisa A, McHugh, Jonathan B, Graham, Martin, Komarck, Christine M, Wolf, Gregory T, Walline, Heather M, Bellile, Emily, Riddell, James, Pai, Sara I, Sidransky, David, Westra, William H, William, William N, Lee, J Jack, El‐Naggar, Adel K, Ferris, Robert L, Seethala, Raja, Grandis, Jennifer R, Chen, Zhuo Georgia, Saba, Nabil F, Shin, Dong M, and consortium, on behalf of the Head and Neck Cancer SPORE HIV supplement

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Immunology, Dental/Oral and Craniofacial Disease, HIV/AIDS, Rare Diseases, Clinical Research, Prevention, Cancer, 2.1 Biological and endogenous factors, Aetiology, Good Health and Well Being, Adult, Aged, Aged, 80 and over, Biomarkers, Tumor, Carcinoma, Squamous Cell, Case-Control Studies, Cause of Death, Combined Modality Therapy, Disease-Free Survival, Female, HIV Infections, HIV Seropositivity, Head and Neck Neoplasms, Humans, Kaplan-Meier Estimate, Logistic Models, Male, Middle Aged, Multivariate Analysis, Prognosis, Proportional Hazards Models, Retrospective Studies, Risk Assessment, Squamous Cell Carcinoma of Head and Neck, Survival Analysis, Transforming Growth Factor beta1, Treatment Outcome, biomarkers, head and neck cancer, human immunodeficiency virus, prognosis, survival, Head and Neck Cancer SPORE HIV supplement consortium, Dentistry, Otorhinolaryngology, Clinical sciences
Abstract

BackgroundWe examined the prognostic value of a panel of biomarkers in patients with squamous cell carcinoma of the head and neck (SCCHN) who were human immunodeficiency virus (HIV) positive (HIV-positive head and neck cancer) and HIV negative (HIV-negative head and neck cancer).MethodsTissue microarrays (TMAs) were constructed using tumors from 41 disease site-matched and age-matched HIV-positive head and neck cancer cases and 44 HIV-negative head and neck cancer controls. Expression of tumor biomarkers was assessed by immunohistochemistry (IHC) and correlations examined with clinical variables.ResultsExpression levels of the studied oncogenic and inflammatory tumor biomarkers were not differentially regulated by HIV status. Among patients with HIV-positive head and neck cancer, laryngeal disease site (P = .003) and Clavien-Dindo classification IV (CD4) counts

Published
2017

15. Polarized hyperspectral microscopic imaging system for enhancing the visualization of collagen fibers and head and neck squamous cell carcinoma.

Author

Ximing Zhou, Ling Ma, Mubarak, Hasan K., Palsgrove, Doreen, Sumer, Baran D., Chen, Amy Y., and Baowei Fei

Subjects
HYPERSPECTRAL imaging systems, SQUAMOUS cell carcinoma, POLARIZERS (Light), STOKES parameters, DATA visualization, COLLAGEN, NECK
Abstract

Significance: Polarized hyperspectral microscopes with the capability of full Stokes vector imaging have potential for many biological and medical applications. Aim: The aim of this study is to investigate polarized hyperspectral imaging (PHSI) for improving the visualization of collagen fibers, which is an important biomarker related to tumor development, and improving the differentiation of normal and tumor cells on pathologic slides. Approach: We customized a polarized hyperspectral microscopic imaging system comprising an upright microscope with a motorized stage, two linear polarizers, two liquid crystal variable retarders (LCVRs), and a compact SnapScan hyperspectral camera. The polarizers and LCVRs worked in tandem with the hyperspectral camera to acquire polarized hyperspectral images, which were further used to calculate four Stokes vectors: S0, S1, S2, and S3. Synthetic RGB images of the Stokes vectors were generated for the visualization of cellular components in PHSI images. Regions of interest of collagen, normal cells, and tumor cells in the synthetic RGB images were selected, and spectral signatures of the selected components were extracted for comparison. Specifically, we qualitatively and quantitatively investigated the enhanced visualization and spectral characteristics of dense fibers and sparse fibers in normal stroma tissue, fibers accumulated within tumors, and fibers accumulated around tumors. Results: By employing our customized polarized hyperspectral microscope, we extract the spectral signatures of Stokes vector parameters of collagen as well as of tumor and normal cells. The measurement of Stokes vector parameters increased the image contrast of collagen fibers and cells in the slides. Conclusions: With the spatial and spectral information from the Stokes vector data cubes (S0, S1, S2, and S3), our PHSI microscope system enhances the visualization of tumor cells and tumor microenvironment components, thus being beneficial for pathology and oncology. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Neonatal Skin

Author

Trevino, Julian, primary, Usedom, Elizabeth, additional, and Chen, Amy Y-Y., additional

Published
2020
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17. Vascular Anomalies

Author

Lee, Grace L., primary, Trevino, Julian, additional, Andrasik, Wyatt, additional, and Chen, Amy Y-Y., additional

Published
2020
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19. Commentary on This Article from Chemoprevention of Head and Neck Cancer with Celecoxib and Erlotinib: Results of a Phase Ib and Pharmacokinetic Study

Author

Saba, Nabil F., primary, Hurwitz, Selwyn J., primary, Kono, Scott A., primary, Yang, Chung S., primary, Zhao, Yang, primary, Chen, Zhengjia, primary, Sica, Gabe, primary, Müller, Susan, primary, Moreno-Williams, Rachel, primary, Lewis, Melinda, primary, Grist, William, primary, Chen, Amy Y., primary, Moore, Charles E., primary, Owonikoko, Taofeek K., primary, Ramalingam, Suresh, primary, Beitler, Jonathan J., primary, Nannapaneni, Sreenivas, primary, Shin, Hyung Ju C., primary, Grandis, Jennifer R., primary, Khuri, Fadlo R., primary, Chen, Zhuo Georgia, primary, and Shin, Dong M., primary

Published
2023
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20. Data from Chemoprevention of Head and Neck Cancer with Celecoxib and Erlotinib: Results of a Phase Ib and Pharmacokinetic Study

Author

Saba, Nabil F., primary, Hurwitz, Selwyn J., primary, Kono, Scott A., primary, Yang, Chung S., primary, Zhao, Yang, primary, Chen, Zhengjia, primary, Sica, Gabe, primary, Müller, Susan, primary, Moreno-Williams, Rachel, primary, Lewis, Melinda, primary, Grist, William, primary, Chen, Amy Y., primary, Moore, Charles E., primary, Owonikoko, Taofeek K., primary, Ramalingam, Suresh, primary, Beitler, Jonathan J., primary, Nannapaneni, Sreenivas, primary, Shin, Hyung Ju C., primary, Grandis, Jennifer R., primary, Khuri, Fadlo R., primary, Chen, Zhuo Georgia, primary, and Shin, Dong M., primary

Published
2023
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25. Supplementary Table 1 from Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies

Author

Shin, Dong M., primary, Zhang, Hongzheng, primary, Saba, Nabil F., primary, Chen, Amy Y., primary, Nannapaneni, Sreenivas, primary, Amin, A.R.M. Ruhul, primary, Müller, Susan, primary, Lewis, Melinda, primary, Sica, Gabriel, primary, Kono, Scott, primary, Brandes, Johann C., primary, Grist, William J., primary, Moreno-Williams, Rachel, primary, Beitler, Jonathan J., primary, Thomas, Sufi M., primary, Chen, Zhengjia, primary, Shin, Hyung Ju C., primary, Grandis, Jennifer R., primary, Khuri, Fadlo R., primary, and Chen, Zhuo Georgia, primary

Published
2023
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26. Supplementary Table from Phase Ib Study of Chemoprevention with Green Tea Polyphenon E and Erlotinib in Patients with Advanced Premalignant Lesions (APL) of the Head and Neck

Author

Shin, Dong M., primary, Nannapaneni, Sreenivas, primary, Patel, Mihir R., primary, Shi, Qiuying, primary, Liu, Yuan, primary, Chen, Zhengjia, primary, Chen, Amy Y., primary, El-Deiry, Mark W., primary, Beitler, Jonathan J., primary, Steuer, Conor E., primary, Roser, Steven M., primary, Klein, Adam M., primary, Owonikoko, Taofeek K., primary, Ramalingam, Suresh S., primary, Khuri, Fadlo R., primary, Chen, Zhuo G., primary, and Saba, Nabil F., primary

Published
2023
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27. Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin from Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin

Author

Wang, Xu, primary, Beitler, Jonathan J., primary, Huang, Wen, primary, Chen, Guo, primary, Qian, Guoqing, primary, Magliocca, Kelly, primary, Patel, Mihir R., primary, Chen, Amy Y., primary, Zhang, Jun, primary, Nannapaneni, Sreenivas, primary, Kim, Sungjin, primary, Chen, Zhengjia, primary, Deng, Xingming, primary, Saba, Nabil F., primary, Chen, Zhuo Georgia, primary, Arbiser, Jack L., primary, and Shin, Dong M., primary

Published
2023
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28. Sppelementary Figures from Phase Ib Study of Chemoprevention with Green Tea Polyphenon E and Erlotinib in Patients with Advanced Premalignant Lesions (APL) of the Head and Neck

Author

Shin, Dong M., primary, Nannapaneni, Sreenivas, primary, Patel, Mihir R., primary, Shi, Qiuying, primary, Liu, Yuan, primary, Chen, Zhengjia, primary, Chen, Amy Y., primary, El-Deiry, Mark W., primary, Beitler, Jonathan J., primary, Steuer, Conor E., primary, Roser, Steven M., primary, Klein, Adam M., primary, Owonikoko, Taofeek K., primary, Ramalingam, Suresh S., primary, Khuri, Fadlo R., primary, Chen, Zhuo G., primary, and Saba, Nabil F., primary

Published
2023
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35. A Multicenter Randomized Phase II Study of Single Agent Efficacy and Optimal Combination Sequence of Everolimus and Pasireotide LAR in Advanced Thyroid Cancer

Author

Bauman, Julie E., primary, Chen, Zhengjia, additional, Zhang, Chao, additional, Ohr, James P., additional, Ferris, Robert L., additional, McGorisk, Gerald M., additional, Brandt, Stephen, additional, Srivatsa, Sumathi, additional, Chen, Amy Y., additional, Steuer, Conor E., additional, Shin, Dong M., additional, Saba, Nabil F., additional, Khuri, Fadlo R., additional, and Owonikoko, Taofeek K., additional

Published
2022
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39. Pediatric intraoperative nerve monitoring during thyroid surgery: A review from the American Head and Neck Society Endocrine Surgery Section and the International Neural Monitoring Study Group

Author

Diercks, Gillian R., primary, Rastatter, Jeff C., additional, Kazahaya, Ken, additional, Kamani, Dipti, additional, Quintanilla‐Dieck, Lourdes, additional, Shindo, Maisie L., additional, Hartnick, Christopher, additional, Shin, Jennifer J., additional, Singer, Michael C., additional, Stack, Brendan C., additional, Chen, Amy Y., additional, St. John, Maie A., additional, Scharpf, Joseph, additional, Agrawal, Nishant, additional, Jayawardena, Asitha D. L., additional, Iwata, Ayaka J., additional, Okose, Okenwa, additional, Wang, Bo, additional, McIlroy, Dioan, additional, Cheung, Anthony, additional, Wu, Che Wei, additional, Chiang, Feng Yu, additional, Dionigi, Gianlorenzo, additional, Barczynski, Marcin, additional, Brauckhoff, Katrin, additional, Lorenz, Kerstin, additional, Hartl, Dana, additional, Tolley, Neil, additional, Brooks, Jennifer A., additional, Schneider, Rick, additional, Dralle, Henning, additional, Abdelhamid Ahmed, Amr H., additional, and Randolph, Gregory W., additional

Published
2022
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43. Work-to-family effects of inclusive leadership: The roles of work-to-family positive spillover and complementary values.

Author

Hong Zhu and Chen, Amy Y. Y.

Subjects
INCLUSIVE leadership
Abstract

Drawing on work--family enrichment theory, we explore whether inclusive leadership leads to employees' work-to-family positive spillover, which further improves their family performance. We also focus on the moderating role of complementary values. A time-lagged study was conducted and the sample included 292 employees from two hotels. The results indicate that inclusive leadership triggers employees' work-to-family positive spillover, and then their family performance is enhanced. Moreover, employees' complementary values may strengthen the positive effect of inclusive leadership. We also provide theoretical and practical implications of the results. [ABSTRACT FROM AUTHOR]

Published
2022
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47. Phase 1 and pharmacokinetic study of everolimus in combination with cetuximab and carboplatin for recurrent/metastatic squamous cell carcinoma of the head and neck

Author

Saba, Nabil F., Hurwitz, Selwyn J., Magliocca, Kelly, Kim, Sungjin, Owonikoko, Taofeek K., Harvey, Donald, Ramalingam, Suresh S., Chen, Zhengjia, Rogerio, Jackie, Mendel, Jennifer, Kono, Scott A., Lewis, Colleen, Chen, Amy Y., Higgins, Kristin, El-Deiry, Mark, Wadsworth, Trad, Beitler, Jonathan J., Shin, Dong M., Sun, Shi-Yong, and Khuri, Fadlo R.

Published
2014
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50. Perioperative pain management and opioid‐reduction in head and neck endocrine surgery: An American Head and Neck Society Endocrine Surgery Section consensus statement

Author

Ferrell, Jay K., primary, Shindo, Maisie L., additional, Stack, Brendan C., additional, Angelos, Peter, additional, Bloom, Gary, additional, Chen, Amy Y., additional, Davies, Louise, additional, Irish, Jonathan C., additional, Kroeker, Teresa, additional, McCammon, Susan D., additional, Meltzer, Charles, additional, Orloff, Lisa A., additional, Panwar, Aru, additional, Shin, Jennifer J., additional, Sinclair, Catherine F., additional, Singer, Michael C., additional, Wang, Tiffany V., additional, and Randolph, Gregory W., additional

Published
2021
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