38 results on '"Cheng, Keguang"'
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2. Synthesis of polycyclic fused oxazolidin-2-ones by catalytic Boron(III)-Promoted oxo-Michael addition reaction and evaluation on their cytotoxicity
3. Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors
4. Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with l-phenylalanine or l-proline
5. Renieramycin-type alkaloids from marine-derived organisms: Synthetic chemistry, biological activity and structural modification
6. Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid
7. Radical Acylfluoroalkylation of 1,3-Enynes via N‑Heterocyclic Carbene/Photoredox Cooperative Catalysis.
8. Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I
9. N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure–activity relationships and X-ray crystallographic studies
10. Rapid Formation of Intramolecular Disulfide Bridges using Light: An Efficient Method to Control the Conformation and Function of Bioactive Peptides
11. Synthesis of scutellarein derivatives with antiproliferative activity and selectivity through the intrinsic pathway
12. Scutellarin derivatives as apoptosis inducers: Design, synthesis and biological evaluation
13. Acylmonofluoromethylation of alkenes via dual NHC/photoredox catalysis
14. (4-Picolylamino)-17β-Estradiol derivative and analogues induce apoptosis with death receptor trail R2/DR5 in MCF-7
15. Synthesis of Polycyclic Fused Oxazolidin-2-Ones by Catalytic Boron(Iii)-Promoted Oxo-Michael Addition Reaction and Evaluation on Their Cytotoxicity
16. Design, synthesis, nitric oxide release and antibacterial evaluation of novel nitrated ocotillol-type derivatives
17. Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with -phenylalanine or -proline
18. Discovery of the First Selective Nanomolar Inhibitors of Endoplasmic Reticulum Aminopeptidase 2 by Kinetic Target‐Guided Synthesis
19. Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis
20. Synthesis and in Vitro/In Vivo Anticancer Evaluation of Pentacyclic Triterpenoid Derivatives Linked with L-Phenylalanine or L-Proline
21. Recombinant expression of different mutant K-ras gene in pancreatic cancer Bxpc-3 cells and its effects on chemotherapy sensitivity
22. Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction
23. Simultaneous reduction of aldehyde group to hydroxymethyl group in palladium-catalyzed Suzuki cross-coupling reaction
24. New possible silver lining for pancreatic cancer therapy: Hydrogen sulfide and its donors
25. Design, synthesis and apoptosis-related antiproliferative activities of chelidonine derivatives
26. Development of Therapeutic Gramicidin S Analogues Bearing Plastic β,γ‐Diamino Acids
27. Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation
28. Discovery of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Agonists by Virtual Screening and Biological Evaluation
29. Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain
30. Synthesis, Cytotoxicity and Antimicrobial Activity of New Enmein-type Kauranoid Diterpenoid Derivatives
31. Estimation of elimination half-lives of organic chemicals in humans using gradient boosting machine
32. Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound
33. Synthesis, Biological Activity, and Apoptotic Properties of NO-Donor/Enmein-Type ent-Kauranoid Hybrids
34. Antitumor and Antibacterial Derivatives of Oridonin: A Main Composition of Dong-Ling-Cao
35. Synthesis, Cytotoxicity and Antimicrobial Activity of New Enmein-type Kauranoid Diterpenoid Derivatives
36. N-Heterocyclic Carbene and Manganese Synergistic Catalysis: A Three-Component Radical Acylmonofluoroalkylation of Alkenes
37. Recombinant expression of different mutant K-rasgene in pancreatic cancer Bxpc-3 cells and its effects on chemotherapy sensitivity
38. Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.
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