36 results on '"Di Felice M"'
Search Results
2. Conceptual Design of a Liquid Helium Vertical Test-Stand for 2m long Superconducting Undulator Coils
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Marchetti, B., primary, Abeghyan, S., additional, Baader, J., additional, Barbanotti, S., additional, Casalbuoni, S., additional, Di Felice, M., additional, Eckoldt, H.-J., additional, Englisch, U., additional, Grattoni, V., additional, Grau, A., additional, Hauberg, A., additional, Jensch, K., additional, La Civita, D., additional, Lederer, S., additional, Lilje, L., additional, Ramalingam, R., additional, Schnautz, T., additional, Vannoni, M., additional, Yakopov, M., additional, Zimmermann, R., additional, and Ziolkowski, P., additional
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- 2022
- Full Text
- View/download PDF
3. Improving Video Delivery with Fourier Analysis of Traffic in Multi-Access Edge Computing
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Di Felice, Marco, Natalizio, Enrico, Bruno, Raffaele, Kassler, Andreas, Di Felice, M ( Marco ), Natalizio, E ( Enrico ), Bruno, R ( Raffaele ), Kassler, A ( Andreas ), Schiller, Eryk; https://orcid.org/0000-0003-2187-0382, Röthlisberger, Remo, Braun, Torsten, Karimzadeh, Mostafa, Di Felice, Marco, Natalizio, Enrico, Bruno, Raffaele, Kassler, Andreas, Di Felice, M ( Marco ), Natalizio, E ( Enrico ), Bruno, R ( Raffaele ), Kassler, A ( Andreas ), Schiller, Eryk; https://orcid.org/0000-0003-2187-0382, Röthlisberger, Remo, Braun, Torsten, and Karimzadeh, Mostafa
- Abstract
This paper presents a new video delivery scheme in mobile networks using Multi-Access Edge Computing (MEC). Our goal is to improve the quality of video streaming experienced by the mobile video consumer. Our approach is based upon Dynamic Adaptive Streaming over HTTP. We present a novel algorithm, which uses information obtained from the Radio Network Information Service of MEC to provide the mobile user with a video quality matching the current radio link quality and channel capacity. We evaluate our approach using a real experiment performed on a Long Term Evolution (LTE) femto cell test-bed. Our algorithm displays enhanced adaptation of video rates in comparison to other state of the art solutions.
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- 2019
4. The SASE1 X-ray beam transport system
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Sinn, H., primary, Dommach, M., additional, Dickert, B., additional, Di Felice, M., additional, Dong, X., additional, Eidam, J., additional, Finze, D., additional, Freijo-Martin, I., additional, Gerasimova, N., additional, Kohlstrunk, N., additional, La Civita, D., additional, Meyn, F., additional, Music, V., additional, Neumann, M., additional, Petrich, M., additional, Rio, B., additional, Samoylova, L., additional, Schmidtchen, S., additional, Störmer, M., additional, Trapp, A., additional, Vannoni, M., additional, Villanueva, R., additional, and Yang, F., additional
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- 2019
- Full Text
- View/download PDF
5. Mobile applications in tourism: a taxonomy an case studies
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MARIANI, MARCELLO MARIA, Di Felice M., Mariani MM, and Di Felice M
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GeneralLiterature_INTRODUCTORYANDSURVEY ,Taxonomy, mobile applications, tourism, strategic management, marketing, European cities - Abstract
This papers proposes an refinement of the taxonomy of mobile apps in tourism roposed by Kennedy-Eden and Gretzel (2012) from two perspectives: a taxonomy on what services travel-related apps provide to the user and a taxonomy based on the functionalities. The taxonomies provide insights into app development trends as well as gaps in the mobile app landscape. A few emblematic case studies from European cities are analysed. Managerial and policy making implications are provided.
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- 2015
6. Workshop message: CORAL 2016
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Di Felice, M., Gao, Y. F., Bedogni, L., Akan, O., Altintas, O., Au, E., Bansal, G., Bayhan, S., Caetano, M. F., Canberk, B., Cavalcanti, D., De, S., Dias, K., Feng, Z., and Fiore, M.
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Cognitive radio ,business.industry ,Computer science ,media_common.quotation_subject ,Telecommunications ,business ,ComputingMilieux_MISCELLANEOUS ,Conjunction (grammar) ,Pleasure ,media_common - Abstract
It is our great pleasure to welcome you to the Fourth IEEE International Workshop on Emerging COgnitive Radio Applications and aLgorithms (CORAL 2016), held in Coimbra, Portugal on June 21, 2016, in conjunction with the IEEE WoWMoM 2016 Conference.
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- 2016
7. The economic impact of moderate stage Alzheimer's disease in Italy: Evidence from the UP-TECH randomized trial
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Chiatti, C., Furneri, G., Rimland, J. M., Demma, F., Bonfranceschi, F., Cassetta, L., Masera, F. b, Cherubini, Corsonello, A., Lattanzio, F., Baldassarri, D., Bitti, L., Carosi, A., Sabbatini, M., Paolasini, E., Fiori, T., Fronzi, C., Giacchetta, S., Giacomini, V., Giovagnoli, L., Lattanzi, G., Manca, A. M., Marinelli, I., Pigini, V., Pignotti, M., Proietti, M. C., Quarticelli, A., Rovedi, M., Tasso, L., Valeri, V., Antonioli, A., Barabucci, M., Bassani, M., Bollettini, P., Bruttapasta, M. C., Buccolini, C., Carangella, R., Carboni, F., Ceccolini, D., D'Incecco, P., Di Felice, M., Dini, L., Gioia, G., Di Prima, G., Giusepponi, G., Lanciotti, C., Loffreda, A., Luciani, O., Mariani, L., Mastrorilli, F., Moroni, R., Piatkowska, I., Rucoli, R., Scoccia, G., Teodori, N., Tonelli, T., Angeloni, R., Bratti, R. A., Bonafede, G., Lorenzetti, S., Paci, C., Picciotti, G., Pezzola, D., Rea, V., Scialè, V., Signorino, M., Sorvillo, F., Tomassini, P. F., Ciccola, A., Cionfrini, L., Alessandrini, D., De Santis, A., Formica, B., Tacchi, G., Tortorelli, S., Marchegiani, G., Pozzari, G., Santarelli, G., Bartolucci, D., Caraffa, G., Cavallo, Filippo, Di Furia, L., Lacetera, A., Maffei, C. M., Manzoli, L., Postacchini, D., Bevilacqua, R., Bonfigli, A. R., Bustacchini, S., Capasso, M., Civerchia, P., Di Rosa, M., Giuli, C., Marcellini, M., Marinelli, P., Melchiorre, G., Moraca, M. E., Principi, A., Rocchetti, C., Spazzafumo, L., Vincitorio, D., Bartulewicz, K., Olivetti, P., and Rossi, L.
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Gerontology ,Male ,very elderly ,cost of illness ,Public expenditure ,morbidity ,residential care ,community care ,Italian (citizen) ,cost analysis ,Surveys and Questionnaires ,Health care ,Activities of Daily Living ,80 and over ,Medicine ,organization and management ,caregiver ,media_common ,Aged, 80 and over ,Public sector ,Mini Mental State Examination ,aged ,Alzheimer disease ,Article ,controlled study ,daily life activity ,disease severity ,economic aspect ,female ,health care ,health care cost ,human ,Italy ,major clinical study ,mortality ,physical performance ,prescription ,prevalence ,randomized controlled trial ,scoring system ,social care ,socioeconomics ,welfare ,economics ,male ,quality of life ,questionnaire ,statistical model, Activities of Daily Living ,Aged ,Alzheimer Disease ,Caregivers ,Cost of Illness ,Female ,Health Expenditures ,Humans ,Linear Models ,Quality of Life ,Alzheimer's disease ,community-living ,RCT ,UP-TECH ,Psychiatry and Mental health ,Clinical Psychology ,Alzheimer’s disease ,media_common.quotation_subject ,Quality of life (healthcare) ,Dementia ,Medical prescription ,Socioeconomic status ,business.industry ,statistical model ,medicine.disease ,Geriatrics and Gerontology ,business ,Welfare - Abstract
Background:There is consensus that dementia is the most burdensome disease for modern societies. Few cost-of-illness studies examined the complexity of Alzheimer's disease (AD) burden, considering at the same time health and social care, cash allowances, informal care, and out-of-pocket expenditure by families.Methods:This is a comprehensive cost-of-illness study based on the baseline data from a randomized controlled trial (UP-TECH) enrolling 438 patients with moderate AD and their primary caregiver living in the community.Results:The societal burden of AD, composed of public, patient, and informal care costs, was about €20,000/yr. Out of this, the cost borne by the public sector was €4,534/yr. The main driver of public cost was the national cash-for-care allowance (€2,324/yr), followed by drug prescriptions (€1,402/yr). Out-of-pocket expenditure predominantly concerned the cost of private care workers. The value of informal care peaked at €13,590/yr. Socioeconomic factors do not influence AD public cost, but do affect the level of out-of-pocket expenditure.Conclusion:The burden of AD reflects the structure of Italian welfare. The families predominantly manage AD patients. The public expenditure is mostly for drugs and cash-for-care benefits. From a State perspective in the short term, the advantage of these care arrangements is clear, compared to the cost of residential care. However, if caregivers are not adequately supported, savings may be soon offset by higher risk of caregiver morbidity and mortality produced by high burden and stress. The study has been registered on the website www.clinicaltrials.org (Trial Registration number: NCT01700556).
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- 2015
8. Structural Health Monitoring and Prognostic of Industrial Plants and Civil Structures: A Sensor to Cloud Architecture
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Federica Zonzini, Nicola Testoni, Cristiano Aguzzi, Luca Sciullo, Marco Di Felice, Alessandro Marzani, Luca De Marchi, Canio Mennuti, Tullio Salmon Cinotti, Lorenzo Gigli, Zonzini F., Aguzzi C., Gigli L., Sciullo L., Testoni N., De Marchi L., Di Felice M., Cinotti T.S., Mennuti C., and Marzani A.
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Computer architecture, Tools, Sensors, Task analysis, Monitoring, Civil engineering, Testing ,Distributed database ,Computer science ,020208 electrical & electronic engineering ,Interoperability ,02 engineering and technology ,Predictive maintenance ,Web of Things ,Component-based software engineering ,Scalability ,0202 electrical engineering, electronic engineering, information engineering ,Systems engineering ,Structural health monitoring ,Electrical and Electronic Engineering ,Instrumentation ,Wireless sensor network - Abstract
The deployment of Structural Health Monitoring (SHM) systems is a natively interdisciplinary task that involves joint research contributions from sensing technologies, data science and civil engineering. The capability to assess, also from remote stations, the working conditions of industrial plants or the structural integrity of civil buildings is widely requested in many application fields. The technological development aims to continuously provide innovative tools and approaches to satisfy these demands. As a first instance, reliable monitoring strategies are needed to detect structural damages while filtering out environmental noise. Ongoing solutions to tackle these topics are based on the exploitation of highly customized sensing technologies, such as shaped transducers for Acoustic Emission (AE) testing or Micro-Electro-Mechanical System (MEMS) accelerometers for Operational Modal Analysis (OMA) [1]. On the other hand, effective data acquisition and storage techniques must be employed to cope with the heterogeneity of the sensing devices and with the amount of data produced by collecting raw measured signals. Finally, damage detection and prediction tasks should be computed via data-driven algorithms that can complement the model-based alternatives traditionally used in civil engineering. Layered SHM architectures [2] represent straightforward approaches to address the system complexity originated by this interdisciplinary design; however, few real-world implementations have been presented so far in the literature. In this paper, we overcome these limitations by presenting an Internet of Things (IoT)-based SHM architecture for the predictive maintenance of industrial sites and civil engineering structures and infrastructures. The proposed cyber-physical system includes a monitoring layer, that consists of accelerometer-based sensor networks, a data acquisition layer, built on the recent W3C Web of Things standard [3], and a data storage and analytics layer, which leverages distributed database and Machine Learning tools. We extensively discuss the hardware/software components of the proposed SHM architecture, by stressing its advantages in terms of device versatility, data scalability and interoperability support. Finally, the effectiveness of the system is validated on a real-world use-case, i.e., the monitoring of a metallic frame structure located at the SHM research labs of the University of Bologna, Italy, within the MAC4PRO project [4].
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- 2020
9. From Cloud to Edge: Seamless Software Migration at the Era of the Web of Things
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Lorenzo Gigli, Angelo Trotta, Cristiano Aguzzi, Marco Di Felice, Luca Sciullo, Aguzzi C., Gigli L., Sciullo L., Trotta A., and Di Felice M.
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Performance Evaluation ,Software modernization ,General Computer Science ,Computer science ,Distributed computing ,Interoperability ,Cloud computing ,02 engineering and technology ,Web of Things ,Software ,0202 electrical engineering, electronic engineering, information engineering ,General Materials Science ,Resource management ,Computer architecture ,Orchestration (computing) ,Edge computing ,Mobile edge computing ,business.industry ,Software architecture ,General Engineering ,020206 networking & telecommunications ,Standard ,Edge/Cloud computing ,020201 artificial intelligence & image processing ,lcsh:Electrical engineering. Electronics. Nuclear engineering ,Service Migration ,W3C ,Internet of Thing ,Internet of Things ,business ,lcsh:TK1-9971 ,Web of Things (WoT) - Abstract
The Web of Things (WoT) standard recently promoted by the W3C constitutes a promising approach to devise interoperable IoT systems able to cope with the heterogeneity of software platforms and devices. The WoT architecture envisages interconnected IoT scenarios characterized by a multitude of Web Things (WTs) that interact according to well-defined software interfaces; at the same time, it assumes static allocations of WTs to hosting devices, and it does not cope with the intrinsic dynamicity of IoT environments in terms of time-varying network and computational loads. In this paper, we extend the WoT paradigm for cloud-edge continuum deployments, hence supporting dynamic orchestration and mobility of WTs among the available computational resources. Differently from state-of-art Mobile Edge Computing (MEC) approaches, we heavily exploit the W3C WoT, and specifically its capability to standardize the software interfaces of the WTs, in order to propose the concept of a Migratable WoT (M-WoT), in which WTs are seamlessly allocated to hosts according to their dynamic interactions. Three main contributions are proposed in this paper. First, we describe the architecture of the M-WoT framework, by focusing on the stateful migration of WTs and on the management of the WT handoff process. Second, we rigorously formulate the WT allocation as a multi-objective optimization problem, and propose a graph-based heuristic. Third, we describe a container-based implementation of M-WoT and a twofold evaluation, through which we assess the performance of the proposed migration policy in a distributed edge computing setup and in a real-world IoT monitoring scenario.
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- 2020
10. A GPS-Free Flocking Model for Aerial Mesh Deployments in Disaster-Recovery Scenarios
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Leonardo Montecchiari, Angelo Trotta, Luciano Bononi, Marco Di Felice, Trotta A., Montecchiari L., Di Felice M., and Bononi L.
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Unmanned aerial vehicles (UAVs) ,General Computer Science ,swarm mobility ,Computer science ,Flocking (behavior) ,Quality of service ,Distributed computing ,disaster recovery ,Local positioning system ,Mesh networking ,Testbed ,General Engineering ,Swarm behaviour ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,multi-hop communication ,simulation ,localization ,Assisted GPS ,General Materials Science ,lcsh:Electrical engineering. Electronics. Nuclear engineering ,Flocking (texture) ,lcsh:TK1-9971 - Abstract
In the aftermath of a large-scale emergency, Unmanned Aerial Vehicles (UAVs) can play a key role as mobile communication systems supporting rescue operations on the ground. At the same time, the deployment of autonomous UAV swarms still poses severe challenges in terms of distributed mobility, swarm connectivity and mesh networking. To this purpose, we propose mathsf {ELAPSE} (aErial LocAl Positioning System for Emergency), a novel, distributed framework for aerial mesh deployment that supports discovery and multi-hop connectivity among rescue personnel and emergency requesters. mathsf {ELAPSE} integrates components of swarm mobility, positioning and Quality-of-Service (QoS) support, while targeting UAV devices at different levels of hardware complexity. Three contributions are provided in this study. First, we present a novel, bio-inspired swarm mobility algorithm which natively addresses QoS-based aerial mesh connectivity, coverage of the ground nodes and UAV collision avoidance through the abstraction of virtual springs. Second, we investigates its implementation when geo-location capabilities are not available: to this aim, we propose local-based and cooperative-based techniques through which each UAV can estimate the position of its neighbours, and hence correctly adjust its direction and speed. Third, we analyze the feasibility of the mathsf {ELAPSE} framework through a twofold evaluation: i.e. a large-scale OMNeT++ simulation showing the effectiveness of the distributed mesh formation and localization techniques, and a small-case ground robotic testbed demonstrating the impact of QoS mechanisms on the system operations.
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- 2020
11. Bluetooth Mesh Technology for the Joint Monitoring of Indoor Environments and Mobile Device Localization: A Performance Study
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Leonardo Montecchiari, Angelo Trotta, Luciano Bononi, Marco Di Felice, Montecchiari L., Trotta A., Bononi L., and Di Felice M.
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Internet of Things, Bluetooth Mesh Networking, Performance Evaluation, Localization - Abstract
Bluetooth Mesh is a recent SIG standard enabling the deployment of multi-hop Wireless Sensor Networks (WSNs) over Bluetooth Low Energy (BLE) communication links. The standard introduces many novel and interesting features in the Internet of Things (IoT) domain, such as the seamless integration among sensors and mobile and wearable devices, and the support for a wide range of different IoT application profiles. At the same time, fine-grained assessments of the performance are still needed to understand the potential of the technology. In this paper, we investigate the usage of Bluetooth Mesh solutions for the joint monitoring of indoor spaces and humans. Through the deployment of a test-bed, we evaluate the performance of Bluetooth Mesh WSNs under varying traffic loads and network sizes. In addition, by exploiting the short-range, multi-hop communications, we propose a procedure for the indoor localization of mobile devices and evaluate its accuracy. The results demonstrate that the technology supports reasonable delivery ratio under high traffic loads, however the network and localization performance sharply decreases when increasing the number of hops between the source and destination nodes.
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- 2022
12. WoTwins: Automatic Digital Twin Generator for the Web of Things
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Luca Sciullo, Angelo Trotta, Federico Montori, Luciano Bononi, Marco Di Felice, Sciullo L., Trotta A., Montori F., Bononi L., and Di Felice M.
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Internet of Things, W3C Web of Things, Digital Twin, Markov Decision Process, Machine Learning, Simulation - Abstract
Digital Twins are crucial in Industry 4.0 IoT scenarios, as they replicate physical assets and enable important tasks such as predictive analytics, what-if scenarios and real time monitoring. The heterogeneity of IoT use cases usually makes the development of digital twins extremely application-specific as well as prone to interoperability issues. To overcome these two challenges, we propose WoTwins, a framework that, on one side, leverages the W3C Web of Things (WoT) standard to model data and entities, and, on the other side, generates automatically Digital Twins of existing Web Things by modeling their state space through a Markov Decision Process (MDP) graph and by predicting its behavior though Machine Learning techniques. We conduct experiments on a simulated use cases related to IoT robotics to evaluate our proposal
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- 2022
13. Joint Power Control and Structural Health Monitoring in Industry 4.0 Scenarios using Eclipse Arrowhead and Web of Things
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Carlo Puliafito, Lorenzo Gigli, Ivan Zyrianoff, Federico Montori, Antonio Virdis, Stefano Di Pascoli, Enzo Mingozzi, Marco Di Felice, Puliafito C., Gigli L., Ribeiro Zyrianoff I. D., Montori F., Virdis A., Di Pascoli S., Mingozzi E., and Di Felice M.
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Industry 4.0, Arrowhead, Web of Things, interoperability - Abstract
The integration of legacy IoT ecosystems in Industry 4.0 scenarios requires human effort to adapt single devices. This process would highly benefit from features like device lookup, loose coupling and late binding. In this paper, we tackle the issue of integrating legacy monitoring systems and actuation systems in an industrial scenario, by looking into the Web of Things (WoT) as a communication standard and the Eclipse Arrowhead Framework (AHF) as a service orchestrator. More specifically, we propose a general architectural approach to enable closed-loop automation between the above mentioned legacy systems by leveraging the adaptation of the WoT to the AHF. Then, we develop a rule-based engine that enables the control of the actuation based on sensor values. Finally, we present a proof-of-concept use case where we integrate a Structural Health Monitoring (SHM) scenario with a power control actuation subsystem using the developed components
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- 2022
14. MODRON: A Scalable and Interoperable Web of Things Platform for Structural Health Monitoring
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Cristiano Aguzzi, Luca Sciullo, Tullio Salmon Cinotti, Angelo Trotta, Alessandro Marzani, Marco Di Felice, Luca De Marchi, Lorenzo Gigli, Federica Zonzini, Aguzzi C., Gigli L., Sciullo L., Trotta A., Zonzini F., De Marchi L., Di Felice M., Marzani A., and Cinotti T.S.
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business.industry ,Computer science ,Data management ,020208 electrical & electronic engineering ,010401 analytical chemistry ,Interoperability ,Cloud computing ,02 engineering and technology ,01 natural sciences ,0104 chemical sciences ,Web of Things ,Analytics ,Embedded system ,Scalability ,0202 electrical engineering, electronic engineering, information engineering ,Systems operation W3C Sensor systems Sensors Internet of Things Monitoring Standards ,Structural health monitoring ,business ,Software architecture - Abstract
Recent Structural Health Monitoring (SHM) systems might take advantage of Internet of Things (IoT) technologies for fine-grained and autonomic sensors data management and processing. Moreover, current SHM deployments often demand for the installation of multi-type and heterogeneous sensor devices capable to perform long-term measurements; from here, the need for dedicated software platforms allowing for scalability and interoperability requirements arises. In this paper, we jointly address the two issues above by proposing MODRON, which is a SHM-dedicated IoT platform with sensor-to-cloud support. The software architecture leverages the W3C Web of Things (WoT) standard for multi-source sensors data acquisition and fusion. The platform includes an edge component, implementing the communication with the monitoring layer and the data exposition through WoT Web Things (WTs), and a cloud component, embedding sensor/WT management capabilities, which is in charge of distributed data storage, aggregation, visualization and analytics. We illustrate the abstract MODRON architecture and its current implementation that supports two different SHM sensor types (MEMS accelerometers and piezoelectric devices). In addition, we describe the system operations on a real-world SHM system, i.e. the monitoring of a metallic structure instrumented with multiple sensor networks.
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- 2021
15. Performance Analysis of Multi-hop Communication based on 5G Sidelink for Cooperative UAV Swarms
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Mishra, Debashisha, Trotta, Angelo, Di Felice, Marco, Natalizio, Enrico, Mishra D., Trotta A., Di Felice M., Natalizio E., SIMulating and Building IOT (SIMBIOT), Department of Networks, Systems and Services (LORIA - NSS), Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Department of Computer Science and Engineering, University of Bologna, and Alma Mater Studiorum University of Bologna (UNIBO)
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[INFO.INFO-NI]Computer Science [cs]/Networking and Internet Architecture [cs.NI] ,UAV, 5G, Sidelink ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,ComputingMilieux_MISCELLANEOUS - Abstract
The ability of unmanned aerial vehicles (UAVs) to communicate and cooperate among themselves in an aerial swarm network is of paramount importance for collaborative missions. It enables the swarm to function as a collective unit to plan trajectories, share tasks, coordinate flight route for collision avoidance or to optimize a given mission objective. In this work, a cellular radio interface known as "sidelink"is investigated for establishing efficient UAV-to-UAV (U2U) multi-hop communication within the aerial swarm network. First, we look into the salient features of cellular sidelink (PC5 radio interface) as a key enabler of U2U communication, and then present a multi-hop network model design to extend cellular connectivity services to out-of-coverage UAVs during missions. Using extensive simulations, we evaluate and study the performance of sidelink-assisted multi-hop U2U communication model in terms of the packet delivery ratio (PDR) for different key scheduling parameters of mode-4 sensing-based autonomous resource selection.
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- 2021
16. WoT Micro Servient: Bringing the W3C Web of Things to Resource Constrained Edge Devices
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Luca Sciullo, Angelo Trotta, Ivan Zyrianoff, Marco Di Felice, Sciullo L., Ivan Dimitry Ribeiro Zyrianoff, Trotta A., and Di Felice M.
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Edge device ,Computer science ,business.industry ,W3C Web of Things ,Distributed computing ,Interoperability ,Remote monitoring and control ,performance evaluation ,Web of Things ,embedded system ,Software deployment ,Home automation ,Reference architecture ,Internet of Thing ,business ,Mobile device - Abstract
The chaotic growth of the Internet of Things (IoT) determined a fragmented landscape with a huge number of devices, technologies and platforms available on the market, and consequential issues of interoperability on many system deployments. The recent W3C Web of Things (WoT) standards aimed to ease the deployment of heterogeneous systems by introducing uniform and well-defined software interfaces among the systems’ components. Although the WoT reference architecture is generic and agnostic to the target devices, its widespread adoption depends on the availability of specific tools named Servients, which enable the run-time operations of WoT applications. In this paper we aim at contributing to the adoption of the W3C WoT standards by presenting WoT Micro-Servient (WMS), a framework for bringing the WoT paradigm to the extreme edge of an IoT environment. Through WMS, developers can design, compile and install WoT applications on micro-controllers and embedded systems with constrained hardware capabilities. We describe the architecture and functionalities of the tool, and demonstrate its effectiveness in terms of reduced latency and energy consumption compared to the state-of-art proxy-based solution enabled by Node-wot, i.e. the official implementation of W3C WoT. Finally, we discuss a real-world application related to smart home, where WMS is used to enable a WoT-based remote monitoring and control of indoor plants, by enabling seamless integration between micro-controllers and mobile devices.
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- 2021
17. AirID: Injecting a Custom RF Fingerprint for Enhanced UAV Identification using Deep Learning
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Marco Di Felice, Kunal Sankhe, Subhramoy Mohanti, Kaushik R. Chowdhury, Nasim Soltani, Dheryta Jaisinghani, Mohanti S., Soltani N., Sankhe K., Jaisinghani D., Di Felice M., and Chowdhury K.
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Computer science ,business.industry ,Deep learning ,Real-time computing ,Fingerprint (computing) ,Transmitter ,Physical layer ,020206 networking & telecommunications ,020302 automobile design & engineering ,02 engineering and technology ,Software-defined radio ,Convolutional neural network ,Identification (information) ,0203 mechanical engineering ,0202 electrical engineering, electronic engineering, information engineering ,Wireless ,Radio frequency ,Artificial intelligence ,business ,Receivers Radio frequency Training Wireless communication Testing Radio transmitters Signal to noise ratio - Abstract
We propose a framework called AirID that identifies friendly/authorized UAVs using RF signals emitted by radios mounted on them through a technique called as RF fingerprinting. Our main contribution is a method of intentionally inserting 'signatures' in the transmitted I/Q samples from each UAV, which are detected through a deep convolutional neural network (CNN) at the physical layer, without affecting the ongoing UAV data communication process. Specifically, AirID addresses the challenge of how to overcome the channel-induced perturbations in the transmitted signal that lowers identification accuracy. AirID is implemented using Ettus B200mini Software Defined Radios (SDRs) that serve as both static ground UAV identifiers, as well as mounted on DJI Matrice M100 UAVs to perform the identification collaboratively as an aerial swarm. AirID tackles the well-known problem of low RF fingerprinting accuracy in 'train on one day test on another day' conditions as the aerial environment is constantly changing. Results reveal 98% identification accuracy for authorized UAVs, while maintaining a stable communication BER of 10 -4 for the evaluated cases.
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- 2020
18. Inventory Management through Mini-Drones: Architecture and Proof-of-Concept Implementation
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Davide Cristiani, Filippo Bottonelli, Marco Di Felice, Angelo Trotta, Cristiani Davide, Bottonelli Filippo, Trotta A., and Di Felice M.
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0209 industrial biotechnology ,Process (engineering) ,Computer science ,Testbed ,Data validation ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,020206 networking & telecommunications ,Context (language use) ,02 engineering and technology ,Drone ,Identification (information) ,n/a ,020901 industrial engineering & automation ,Software deployment ,0202 electrical engineering, electronic engineering, information engineering ,Systems engineering ,Motion planning - Abstract
Warehouse management is a crucial task for most of nowadays' business activities. The usage of small Unmanned Aerial Vehicles (UAVs) has been recently proposed to automatize the inventory process while increasing the safety for human workers. However, the practical deployment of UAV swarms in the target use-case must face many severe technical issues, such as the indoor navigation, the package identification and the limited flight autonomy of the drones. In this challenging context, the paper addresses three novel research contributions. First, we propose a generic architecture for UAV-based inventory management within large-scale warehouses, including the components of UAV path planning, package identification (via QR Codes), data validation (via the Blockchain) and wireless charging; a prototype implementation of the data acquisition and management framework has been conducted by using low-cost mini-drones and single-board computers. Second, we analyze the system performance and specifically the trade-off between the inventory accuracy, i.e. rate of successful package identification, and the inventory completion time. Third, we derive the optimal UAV mobility parameters in terms of speed and number of visits for each shelf unit, and test the system operations and the configuration parameters through a small-case testbed.
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- 2020
19. Discovering Web Things as Services within the Arrowhead Framework
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Federico Montori, Tullio Salmon Cinotti, Marco Di Felice, Luca Sciullo, Angelo Trotta, Sciullo L., Montori F., Trotta A., Di Felice M., and Cinotti T.S.
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Computer science ,business.industry ,computer.internet_protocol ,Arrowhead ,Interoperability ,Potential candidate ,020206 networking & telecommunications ,Cloud computing ,interoperability ,02 engineering and technology ,Service-oriented architecture ,platform integration ,World Wide Web ,Web of Things ,Order (exchange) ,Arrowhead framework ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Architecture ,business ,computer - Abstract
The IoT is spreading heavily around us and many new standard at different architectural layers proliferate. This creates a heavy interoperability gap that many architectural proposals and new standards have tried to cope with over the years. In particular, we take into account the Arrowhead interoperability Framework, a powerful and promising paradigm for interconnecting local clouds and we demonstrate the possibility to integrate it with the emerging W3C Web of Things standard. We study the usage of the Arrowhead Framework as a potential candidate for discovery operation and inclusion of WoT ecosystems within Service Oriented Architectures (SOA), in order to support the integration of legacy and proprietary systems. To this aim, a three-layered architecture is proposed and validated experimentally on a proof-of-concept use case, by highlighting the advantages of the proposed integration.
- Published
- 2020
- Full Text
- View/download PDF
20. Design and performance evaluation of a LoRa-based mobile emergency management system (LOCATE)
- Author
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Marco Di Felice, Luca Sciullo, Angelo Trotta, Sciullo L., Trotta A., and Di Felice M.
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Computer Networks and Communications ,business.industry ,Computer science ,010401 analytical chemistry ,020206 networking & telecommunications ,02 engineering and technology ,Communications system ,01 natural sciences ,0104 chemical sciences ,Flooding (computer networking) ,Internet of things (IoT) ,Hardware and Architecture ,Lora technology ,Scalability ,0202 electrical engineering, electronic engineering, information engineering ,Global Positioning System ,Performance evaluation ,Data dissemination protocol ,Emergency communication system (ECS) ,business ,Trilateration ,Software ,Computer network - Abstract
Smartphone devices can play a key role on emergency scenarios thanks to their pervasiveness, and the possibility to convey emergency requests from the involved people to the rescue teams. At the same time, the effective utilization of such devices on critical scenarios with limited mobile Internet access is challenging. As an alternative, several recent research studies have proposed Emergency Communication System (ECS) based on short-range Device-to-Device (D2D) solutions available on Commercial Off The Shelf (COTS) devices (e.g. Wi-Fi Direct); however, the target of these solutions is constituted by small indoor areas, since the scalability on large-scale environments is often a problem. In this paper, we overcome such issue by proposing LOCATE , a novel phone-based ECS enabling long-range communication among survivors and rescue teams over critical environments where 3/4G cellular connectivity is not available and the traditional geo-localization technologies (e.g. the GPS) provide only partial coverage of the environment. The proposed system consists of a mobile application connected to a LoRa transceiver via Bluetooth Low Energy (BLE); through the app, users can send emergency requests that are re-broadcasted by other peers until reaching a rescue personnel who is able to handle the emergency. Three novel contributions are provided in this paper. First, we provide extensive measurements of the LoRa technology, and investigate its suitability for ECS-related applications. Second, we describe the LOCATE prototype and the enabling algorithms; specifically, we propose a novel multi-hop dissemination algorithm which maximizes the probability to deliver an emergency request to the destination (e.g. rescue personnel) within a user-defined temporal threshold, while minimizing the number of message re-transmissions. Third, we extensively evaluate the LOCATE performance through OMNeT++ simulations, assessing the capability of the dissemination protocol to spread out the emergency requests over large-scale scenarios, and through experiments, assessing the capability of LoRa-based trilateration technique to provide accurate GPS-free localization. The results demonstrate that the LOCATE protocol is able to minimize the time required to handle the emergency when compared to other dissemination strategies (e.g. flooding, continuous, once-per-contact), and they highlight the considerable improvement provided by the LoRa technology over other D2D solutions available on COTS smartphones (e.g. Wi-Fi Direct).
- Published
- 2020
21. Throughput Enhancement in UAV-aided Wireless Sensor Networks via Wake-Up Radio Technology and Priority-based MAC Scheme
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Tullio Salmon Cinotti, Luca Perilli, Eleonora Franchi Scarselli, Marco Di Felice, Angelo Trotta, Luciano Bononi, Trotta A., Di Felice M., Bononi L., Perilli L., Scarselli Eleonora Franchi, and Cinotti T.S.
- Subjects
Wake-Up Radio ,business.industry ,Computer science ,010401 analytical chemistry ,05 social sciences ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,050801 communication & media studies ,Throughput ,Energy consumption ,01 natural sciences ,Synchronization ,0104 chemical sciences ,0508 media and communications ,PHY ,Wireless ,business ,Wireless sensor network ,UAV, Wireless Sensor Networks ,Computer network ,Communication channel - Abstract
UAV-aided Wireless Sensor Networks (WSNs) constitute an energy- and cost-effective solution for the deployment of large-scale IoT monitoring systems. At the same time, the integration of UAVs into IoT scenarios poses some practical challenges which are far to be addressed, like the synchronization issue (how can the Wireless Ground Sensors (WGSs) be aware of the presence of the UAV?) and the channel contention in high-dense scenarios (how can the WGSs cope with the limited transmission opportunity?). In this paper, we address both the issues above by proposing a novel Energy Load Aware Sensor To aIr Communication (ELASTIC) platform, supporting the deployment of scalable and energy-efficient UAV-aided WSNs. The proposal includes two main components, working in synergy at the PHY and MAC layers. First, the paper describes the design and implementation of Active Wake-up Radio mechanisms through which the WGSs can be notified of the UAV’s presence and hence of the transmission opportunity; the proposed architecture supports two operative modes (Switch and Low-Power) that can be properly orchestrated so that the energy consumption of the WGSs in standby phase is minimized. Second, since multiple WGSs can be activated from a wake-up signal and access the channel at the same time, a novel priority-based MAC scheme has been designed: the proposed solution performs distributed contention control among the WGSs, by taking into account the length of the transmission opportunity for each WGS and the actual channel load. The simulation results demonstrate that the proposed ELASTIC MAC protocol guarantees a +50% throughput improvement when compared to the legacy CSMA/CA MAC in high-dense WSNs, and show its ability to adapt to different traffic loads and UAV speeds.
- Published
- 2020
22. FOCUS: Fog Computing in UAS Software-Defined Mesh Networks
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Gokhan Secinti, Kaushik R. Chowdhury, Marco Di Felice, Angelo Trotta, Subhramoy Mohanti, Secinti G., Trotta A., Mohanti S., Di Felice M., and Chowdhury K.R.
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050210 logistics & transportation ,Computer science ,business.industry ,Mechanical Engineering ,Distributed computing ,05 social sciences ,Mesh networking ,Reconfigurability ,Cloud computing ,Network topology ,Telecommunications network ,Unmanned aerial vehicles ,Computer Science Applications ,Network planning and design ,mobile ad hoc network ,edge computing ,0502 economics and business ,Automotive Engineering ,software defined networking ,heuristic algorithm ,business ,Software-defined networking ,Edge computing - Abstract
Unmanned aerial systems (UASs) allow easy deployment, three-dimensional maneuverability and high reconfigurability, as they sustain communication network in the absence of pre-installed infrastructure. The proposed FOg Computing in UAS Software-defined mesh network (FOCUS) paradigm aims to realize an implementable network design that considers practical issues of aerial connectivity and computation. It allocates UASs to the tasks of data forwarding and in-network fog computing while maximizing number of ground-users in UAS coverage. FOCUS improves efficient utilization of network resources by introducing on-board computation and innovates on top of software-defined networking stack by integrating the capabilities of network and ground controllers to enable simultaneous orchestration of both UASs and communication flows. There are three main contributions of the paper: First, a SDN-based architecture is designed enabling autonomous configuration of computation and communication as well as managing multi-hop aerial links. Second, a global optimization problem to achieve optimal forwarding and computational allocation is formulated using Open Jackson Network model and solved via a heuristic approach with well defined complexity. Third, FOCUS framework is implemented on a small-scale testbed of Intel® Aero UASs performing image analysis with a full software stack. Experiments reveal at least 32% latency improvement in computation service time compared to traditional centralized computation at the end-server or greedy task allocation schemes within the network.
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- 2020
23. Persistent Crowd Tracking Using Unmanned AerIal Vehicle Swarms: A Novel Framework for Energy and Mobility Management
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Kaushik R. Chowdhury, Ufuk Muncuk, Marco Di Felice, Angelo Trotta, Trotta A., Muncuk U., Di Felice M., and Chowdhury K.R.
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Computer science ,Energy management ,Video capture ,business.industry ,Video surveillance ,Real-time computing ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Wireless communication ,Swarm behaviour ,020206 networking & telecommunications ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,Target tracking ,02 engineering and technology ,ComputingMethodologies_ARTIFICIALINTELLIGENCE ,Batterie ,Task (project management) ,Receiver ,Software deployment ,Smart city ,Automotive Engineering ,0202 electrical engineering, electronic engineering, information engineering ,Wireless ,business ,Mobility management ,Radio transmitter - Abstract
Aerial surveillance systems are a cost-effective and on-demand solution for smart city monitoring. However, the deployment of a swarm of unmanned aerial vehicles (UAVs) for continuous video capture of mobile ground target (MGT) activities poses new research issues in terms of energy management, scenario coverage, and multidevice task coordination. In this article, we address these challenges by proposing Persistent Crowd Tracking Using UAVs (PERCEIVE), a novel framework for continuous video surveillance via UAVs that are periodically replenished through mobile charging stations (MCSs).
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- 2020
24. The determinants of Facebook social engagement for national tourism organizations' Facebook pages: A quantitative approach
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Marcello M. Mariani, Marco Di Felice, Matteo Mura, and Mariani, M.M, Mura, M., Di Felice M
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Facebook ,Strategy and Management ,Big data ,Destinations ,Social media ,User engagement ,Political science ,Panel data multivariate regression analyses ,0502 economics and business ,Country destination ,Destination marketing ,Business and International Management ,Marketing ,Engagement ,business.industry ,Social activity ,05 social sciences ,Advertising ,Public relations ,Social engagement ,Tourism, Leisure and Hospitality Management ,050211 marketing ,business ,National Tourism Organization ,050212 sport, leisure & tourism ,Tourism ,Panel data - Abstract
This paper explores how the national tourism organizations (NTOs) of the top 10 most-visited countries by international tourists strategically employ Facebook to promote and market their destinations. Based on big data retrieved from the NTOs’ Facebook pages, and leveraging advanced metrics for capturing user engagement, the study sheds light on the factors contributing to superior level of social activity. The findings indicate that the way Facebook is tactically employed varies significantly across the NTOs. The panel data regression analyses suggest that engagement is positively affected by posting visual content (namely photos), and posting during the weekends, and negatively affected by evening posting. Post frequency displays no statistically significant effect on social engagement. The study also shows that most of the NTOs (except for Italy, Spain, Turkey and the UK) deploy Facebook with a top-down approach, and spontaneous user-generated content (UGC) is allowed to a very little extent.
- Published
- 2018
25. BEE-DRONES: Energy-efficient Data Collection on Wake-Up Radio-based Wireless Sensor Networks
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Tullio Salmon Cinotti, Luciano Bononi, Enrico Natalizio, Luca Perilli, Angelo Trotta, Roberto Canegallo, Eleonora Franchi Scarselli, Marco Di Felice, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), SIMulating and Building IOT (SIMBIOT), Department of Networks, Systems and Services (LORIA - NSS), Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)-Institut National de Recherche en Informatique et en Automatique (Inria), Lin Wang, Stephan Sigg, Trotta A., Di Felice M., Bononi L., Natalizio E., Perilli L., Scarselli E.F., Cinotti T.S., Canegallo R., Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), and Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)
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Optimization problem ,Computer science ,business.industry ,Real-time computing ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,020206 networking & telecommunications ,020302 automobile design & engineering ,02 engineering and technology ,Energy consumption ,7. Clean energy ,Drone ,Scheduling (computing) ,[INFO.INFO-NI]Computer Science [cs]/Networking and Internet Architecture [cs.NI] ,0203 mechanical engineering ,autonomous aerial vehicles, path planning, wireless sensor networks, Energy consumption, Trajectory Optimization ,0202 electrical engineering, electronic engineering, information engineering ,Wireless ,ComputerSystemsOrganization_SPECIAL-PURPOSEANDAPPLICATION-BASEDSYSTEMS ,Motion planning ,business ,Wireless sensor network ,ComputingMilieux_MISCELLANEOUS ,Efficient energy use - Abstract
Several recent studies demonstrated that the utilization of Unmanned Aerial Vehicles (UAVs) in combination with Wireless Sensor Networks (WSNs) can enhance the system performance in terms of lifetime and data delivery ratio; at the same time, the communication among Wireless Ground Sensors (WGSs) and UAVs poses several technical challenges which are far from being solved. Specifically, in this paper, two main issues are addressed: (i) how to ensure seamless synchronization among ground and aerial devices at each transit, and (ii) how to compute energy-efficient schedules for the WGSs and feasible trajectories for the UAVs. To this purpose, BEE-DRONES, a novel framework for data collection in wake-up radio based UAV-aided WSNs is proposed; in order to solve the synchronization issue, a solution where UAVs transfer energy toward selected WGSs is presented. The solution allows WGSs to power down the main radio when not requested. The joint WGSs wake-up scheduling and UAV path planning optimization problem is formulated, by taking into account the limited autonomy of the UAVs, the energy consumption of both UAVs and WGSs, and the data requirements of the applications, and it is solved via a two-step heuristic. The OMNeT++ simulation results demonstrate that the BEE-DRONES framework is able to enhance the WSN lifetime, and to optimize the quality of gathered data in terms of minimal temporal/spatial correlation.
- Published
- 2019
26. BEE-DRONES: Ultra low-power monitoring systems based on unmanned aerial vehicles and wake-up radio ground sensors
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Luca Perilli, Marco Di Felice, Eleonora Franchi Scarselli, Angelo Trotta, Tullio Salmon Cinotti, Trotta A., Di Felice M., Perilli L., Scarselli Eleonora Franchi, and Cinotti T.S.
- Subjects
Computer Networks and Communications ,Computer science ,business.industry ,Mobile broadband ,Real-time computing ,020206 networking & telecommunications ,Unmanned aerial vehicle ,02 engineering and technology ,Wake-Up radio ,Wireless sensor networks ,Drone ,Smart city ,0202 electrical engineering, electronic engineering, information engineering ,Wireless ,020201 artificial intelligence & image processing ,Motion planning ,Wireless power transfer ,business ,Wireless sensor network - Abstract
Nowadays, Unmanned Aerial Vehicles (UAVs) represent a significant aid on scenarios where fixed, ground infrastructures are temporarily or permanently not available; this is the case of large-scale applications of the Internet of Things (IoTs), e.g. smart city and agriculture 3.0, where the UAVs can be employed as mobile data mules and gather the data from Wireless Ground Sensors (WGSs). UAV-aided wireless sensor networks (WSNs) introduce considerable advantages both in terms of performance and costs since they avoid the need of error-prone multi-hop communications, and also the installation of static gateways; at the same time, they pose formidable research challenges for their implementation, like the synchronization issue between the UAV and the WGS and the path planning, which should take into account the extremely limited flight autonomy of the UAVs. In this paper, we address both the issues above by proposing BEE-DRONES , a novel framework for large-scale, ultra low-power UAV-aided WSNs. In order to mitigate the synchronization problem, we investigate the utilization of passive Wake-up Radio (WR) technology on the WGSs, and of wireless power transfer from the UAVs: by harvesting the energy from the UAV hovering over it, the WGS is activated only for the short time required to transfer the data toward the mobile sink, while it experiences zero-consumption in sleep mode. We investigate the performance of passive WR-based WGS through real measurements, under different WGS-UAV distances and antenna orientations. Then, based on such results, we formulate the joint WGS scheduling and UAV path planning problem, where the goal is to determine the optimal trajectory of the UAVs activating the WR-based WGSs while taking into account the Value of the Sensing (VoS) as well as the total lifetime of the WSN. The original problem is transformed into a multi-commodity flow problem, and both centralized and distributed heuristics over the multi-graph are proposed. Finally, we evaluate the proposed algorithms through extensive OMNeT++ simulations; the results demonstrate the gain of BEE-DRONES in terms of extended lifetime compared to traditional, non WR-based solutions (e.g. duty-cycle), and in terms of reduced data-correlation compared to non VoS-aware path planning solutions.
- Published
- 2020
27. Adaptive V2V Routing with RSUs and Gateway Support to Enhance Network Performance in VANET
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Jims Marchang, Dany Joy, Benjamin Sanders, Chowdhury, K. R., Di Felice, M., Matta, A., and Sheng, B.
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Vehicular ad hoc network ,Network packet ,business.industry ,Computer science ,Wireless ad hoc network ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,020302 automobile design & engineering ,020206 networking & telecommunications ,02 engineering and technology ,law.invention ,Hop (networking) ,0203 mechanical engineering ,Path length ,Handover ,Relay ,law ,0202 electrical engineering, electronic engineering, information engineering ,Network performance ,business ,Computer network - Abstract
In a VANET communication, link stability can neither be guaranteed nor make\ud the established route link permanent due to the dynamic nature of the network. In V2V communication\ud without the involvement of any infrastructural units like RSU access points or gateway,\ud the probability of successful link establishment decreases when vehicle’s speed varies, red traffic\ud light increases, cross-road increases and finally when the density of the running vehicles is sparse.\ud To ensure route establishment and control route request broadcast in a sparse VANET with crossroad\ud layout, RSUs are used in this paper for route discovery within one gateway zone when a\ud next hop vehicle to relay the route request packet is unavailable. RSUs are static but the vehicles\ud are dynamic in nature, so relying completely on RSU for forwarding data is not recommended\ud because chances of link failure, link re-establishment, and handoff overhead will be high. So, in\ud this paper, RSUs and Gateways are evoked for route discovery and data forwarding only when\ud necessary. Moreover, a local route repair is attempted in this paper when the path length is high\ud to reduce or avoid loss of buffered packets along the route and to maintain a more stable link\ud with the help of RSUs.
- Published
- 2018
28. A mobile phone-sensing system for emergency management: The SENSE-ME platform
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Stefano Savazzi, Gianluca Aloi, Giuseppe Ruggeri, Marco Di Felice, Tiziana Tambosso, Ermanno Cardelli, Paolo Ciancarini, Aloi, G., Di Felice, M., Ruggeri, G., and Savazzi, S.
- Subjects
Structure (mathematical logic) ,Engineering ,System deployment ,Emergency management ,business.industry ,WiFi Direct ,Distributed computing ,Sensors, Smart phones, Peer-to-peer computing, Data mining, Software, Computer architecture, IEEE 802.11 Standard ,020206 networking & telecommunications ,020207 software engineering ,data mining ,emergency management ,02 engineering and technology ,Network layer ,Software ,Mobile phone ,Spontaneous Networks ,Embedded system ,Distributed Information Processing ,0202 electrical engineering, electronic engineering, information engineering ,Wireless ,Layer (object-oriented design) ,business - Abstract
Modern smartphones integrate multiple functionalities into a single device: they can establish peer-to-peer wireless links, they can sense the environment through several embedded sensors, they are provided with a multi-core CPU. Hence, they can play a crucial role on emergency scenarios, where there is need of acquiring data from the environment, processing, and quickly conveying them to the people involved. In this paper, we describe how to turn a group of dense and heterogeneous smartphones into a phone-sensing platform, through the SENSE-ME software. This latter integrates three layers: (i) a network layer, that allows the creation of a spontaneous device-to-device communication structure; (ii) a sensing layer, that allows retrieving local and remote sensing data; (iii) a decision layer, that allows mining the sensed data, in order to extract context-aware information and -based on them-infer decisions about proper actions to take. In the following, we describe the SENSE-ME architecture and some enabling technologies at each layer. Moreover, we discuss the open challenges that must be addressed for the complete system deployment.
- Published
- 2016
29. Folding and Binding Kinetics of the Tandem of SH2 Domains from SHP2.
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Pagano L, Pennacchietti V, Malagrinò F, Di Felice M, Toso J, Puglisi E, Gianni S, and Toto A
- Subjects
- Adaptor Proteins, Signal Transducing metabolism, Adaptor Proteins, Signal Transducing chemistry, Hydrogen-Ion Concentration, Kinetics, Protein Binding, Protein Folding, Protein Tyrosine Phosphatase, Non-Receptor Type 11 metabolism, Protein Tyrosine Phosphatase, Non-Receptor Type 11 chemistry, src Homology Domains
- Abstract
The SH2 domains of SHP2 play a crucial role in determining the function of the SHP2 protein. While the folding and binding properties of the isolated NSH2 and CSH2 domains have been extensively studied, there is limited information about the tandem SH2 domains. This study aims to elucidate the folding and binding kinetics of the NSH2-CSH2 tandem domains of SHP2 through rapid kinetic experiments, complementing existing data on the isolated domains. The results indicate that while the domains generally fold and unfold independently, acidic pH conditions induce complex scenarios involving the formation of a misfolded intermediate. Furthermore, a comparison of the binding kinetics of isolated NSH2 and CSH2 domains with the NSH2-CSH2 tandem domains, using peptides that mimic specific portions of Gab2, suggests a dynamic interplay between NSH2 and CSH2 in binding Gab2 that modulate the microscopic association rate constant of the binding reaction. These findings, discussed in the context of previous research on the NSH2 and CSH2 domains, enhance our understanding of the function of the SH2 domain tandem of SHP2.
- Published
- 2024
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30. The Mechanism of Folding of Human Frataxin in Comparison to the Yeast Homologue - Broad Energy Barriers and the General Properties of the Transition State.
- Author
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Pietrangeli P, Marcocci L, Pennacchietti V, Diop A, Di Felice M, Pagano L, Malagrinò F, Toto A, Brunori M, and Gianni S
- Subjects
- Humans, Kinetics, Models, Molecular, Mutagenesis, Site-Directed, Protein Conformation, Saccharomyces cerevisiae Proteins chemistry, Saccharomyces cerevisiae Proteins genetics, Thermodynamics, Frataxin chemistry, Frataxin genetics, Protein Folding
- Abstract
The funneled energy landscape theory suggests that the folding pathway of homologous proteins should converge at the late stages of folding. In this respect, proteins displaying a broad energy landscape for folding are particularly instructive, allowing inferring both the early, intermediate and late stages of folding. In this paper we explore the folding mechanisms of human frataxin, an essential mitochondrial protein linked to the neurodegenerative disorder Friedreich's ataxia. Building upon previous studies on the yeast homologue, the folding pathway of human frataxin is thoroughly examined, revealing a mechanism implying the presence of a broad energy barrier, reminiscent of the yeast counterpart. Through an extensive site-directed mutagenesis, we employed a Φ -value analysis to map native-like contacts in the folding transition state. The presence of a broad energy barrier facilitated the exploration of such contacts in both early and late folding events. We compared results from yeast and human frataxin providing insights into the impact of native topology on the folding mechanism and elucidating the properties of the underlying free energy landscape. The findings are discussed in the context of the funneled energy landscape theory of protein folding., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2024
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- View/download PDF
31. The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain.
- Author
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Di Felice M, Pagano L, Pennacchietti V, Diop A, Pietrangeli P, Marcocci L, Di Matteo S, Malagrinò F, Toto A, and Gianni S
- Subjects
- Humans, Binding Sites, Models, Molecular, Protein Structure, Tertiary, GRB2 Adaptor Protein metabolism, GRB2 Adaptor Protein chemistry, GRB2 Adaptor Protein genetics, Protein Binding, Protein Folding, src Homology Domains
- Abstract
The adaptor protein Grb2, or growth factor receptor-bound protein 2, possesses a pivotal role in the transmission of fundamental molecular signals in the cell. Despite lacking enzymatic activity, Grb2 functions as a dynamic assembly platform, orchestrating intracellular signals through its modular structure. This study delves into the energetic communication of Grb2 domains, focusing on the folding and binding properties of the C-SH3 domain linked to its neighboring SH2 domain. Surprisingly, while the folding and stability of C-SH3 remain robust and unaffected by SH2 presence, significant differences emerge in the binding properties when considered within the tandem context compared with isolated C-SH3. Through a double mutant cycle analysis, we highlighted a subset of residues, located at the interface with the SH2 domain and far from the binding site, finely regulating the binding of a peptide mimicking a physiological ligand of the C-SH3 domain. Our results have mechanistic implications about the mechanisms of specificity of the C-SH3 domain, indicating that the presence of the SH2 domain optimizes binding to its physiological target, and emphasizing the general importance of considering supramodular multidomain protein structures to understand the functional intricacies of protein-protein interaction domains., Competing Interests: Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2024
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32. Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering.
- Author
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Diop A, Pietrangeli P, Pennacchietti V, Pagano L, Toto A, Di Felice M, Di Matteo S, Marcocci L, Malagrinò F, and Gianni S
- Subjects
- Histones metabolism, Adaptor Proteins, Signal Transducing metabolism, Protein Engineering, Protein Binding, Tiopronin metabolism, Ubiquitin-Protein Ligases metabolism
- Abstract
Protein-protein interactions play crucial roles in a wide range of biological processes, including metabolic pathways, cell cycle progression, signal transduction, and the proteasomal system. For PPIs to fulfill their biological functions, they require the specific recognition of a multitude of interacting partners. In many cases, however, protein-protein interaction domains are capable of binding different partners in the intracellular environment, but they require precise regulation of the binding events in order to exert their function properly and avoid misregulation of important molecular pathways. In this work, we focused on the MATH domain of the E3 Ligase adaptor protein SPOP in order to decipher the molecular features underlying its interaction with two different peptides that mimic its physiological partners: Puc and MacroH2A. By employing stopped-flow kinetic binding experiments, together with extensive site-directed mutagenesis, we addressed the roles of specific residues, some of which, although far from the binding site, govern these transient interactions. Our findings are compatible with a scenario in which the binding of the MATH domain with its substrate is characterized by a fine energetic network that regulates its interactions with different ligands. Results are briefly discussed in the context of previously existing work regarding the MATH domain.
- Published
- 2023
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- View/download PDF
33. Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands.
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Pennacchietti V, Pagano L, Malagrinò F, Diop A, Di Felice M, Di Matteo S, Marcocci L, Pietrangeli P, Toto A, and Gianni S
- Subjects
- Protein Domains, Phosphotyrosine metabolism, Ligands, Binding Sites, Protein Binding, Peptides metabolism, src Homology Domains
- Abstract
PTB (PhosphoTyrosine Binding) domains are protein domains that exert their function by binding phosphotyrosine residues on other proteins. They are commonly found in a variety of signaling proteins and are important for mediating protein-protein interactions in numerous cellular processes. PTB domains can also exhibit binding to unphosphorylated ligands, suggesting that they have additional binding specificities beyond phosphotyrosine recognition. Structural studies have reported that the PTB domain from FRS2 possesses this peculiar feature, allowing it to interact with both phosphorylated and unphosphorylated ligands, such as TrkB and FGFR1, through different topologies and orientations. In an effort to elucidate the dynamic and functional properties of these protein-protein interactions, we provide a complete characterization of the folding mechanism of the PTB domain of FRS2 and the binding process to peptides mimicking specific regions of TrkB and FGFR1. By analyzing the equilibrium and kinetics of PTB folding, we propose a mechanism implying the presence of an intermediate along the folding pathway. Kinetic binding experiments performed at different ionic strengths highlighted the electrostatic nature of the interaction with both peptides. The specific role of single amino acids in early and late events of binding was pinpointed by site-directed mutagenesis. These results are discussed in light of previous experimental works on these protein systems., (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2023
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34. Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners.
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Diop A, Pietrangeli P, Nardella C, Pennacchietti V, Pagano L, Toto A, Di Felice M, Di Matteo S, Marcocci L, Malagrinò F, and Gianni S
- Subjects
- Humans, Transcription Factors metabolism, Ubiquitination, Repressor Proteins metabolism, Nuclear Proteins metabolism
- Abstract
SPOP (Speckle-type POZ protein) is an E3 ubiquitin ligase adaptor protein that mediates the ubiquitination of several substrates. Furthermore, SPOP is responsible for the regulation of both degradable and nondegradable polyubiquitination of a number of substrates with diverse biological functions. The recognition of SPOP and its physiological partners is mediated by two protein-protein interaction domains. Among them, the MATH domain recognizes different substrates, and it is critical for orchestrating diverse cellular pathways, being mutated in several human diseases. Despite its importance, the mechanism by which the MATH domain recognizes its physiological partners has escaped a detailed experimental characterization. In this work, we present a characterization of the binding mechanism of the MATH domain of SPOP with three peptides mimicking the phosphatase Puc, the chromatin component MacroH2A, and the dual-specificity phosphatase PTEN. Furthermore, by taking advantage of site-directed mutagenesis, we address the role of some key residues of MATH in the binding process. Our findings are briefly discussed in the context of previously existing data on the MATH domain.
- Published
- 2023
- Full Text
- View/download PDF
35. The photon beamline vacuum system of the European XFEL.
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Dommach M, Di Felice M, Dickert B, Finze D, Eidam J, Kohlstrunk N, Neumann M, Meyn F, Petrich M, Rio B, Sinn H, and Villanueva R
- Abstract
The photon beamline vacuum system of the European X-ray Free-Electron Laser Facility (European XFEL) is described. The ultra-large, in total more than 3 km-long, fan-like vacuum system, consisting of three photon beamlines is an essential part of the photon beam transport. It is located between the accelerator vacuum system and the scientific instruments. The main focus of the design was on the efficiency, reliability and robustness of the entire system to ensure the retention of beam properties and the operation of the X-ray optics and X-ray photon diagnostics components. Installation started in late 2014, the first of the three beamline vacuum systems was commissioned in spring 2017, and the last one was operational in mid-2018. The present state and experience from the first years of operation are outlined., (open access.)
- Published
- 2021
- Full Text
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36. Transbrachial approach to the treatment of uterine leiomyomas with embolization of the uterine arteries: a preliminary technical experience.
- Author
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Pieri S, Di Felice M, Moreschi E, Damiani P, Marasca E, Agresti P, Sessa B, Trinci M, Menichini G, Di Giampietro I, and Miele V
- Subjects
- Adult, Contrast Media, Female, Humans, Magnetic Resonance Imaging, Middle Aged, Pain Management, Treatment Outcome, Triiodobenzoic Acids, Ultrasonography, Doppler, Color, Ultrasonography, Interventional, Brachial Artery, Leiomyoma therapy, Uterine Artery Embolization, Uterine Neoplasms therapy
- Abstract
Introduction: Uterine leiomyomas are benign tumours; recently they have been managed with embolization of the uterine arteries. We analysed the technical feasibility, safety and efficacy of this treatment performed via an innovative transbrachial approach, rather than the traditional transfemoral approach., Materials and Methods: Between 2009 and 2013, 115 patients were treated with embolization of the uterine arteries for one or more symptomatic leiomyomas. In 20 of these 115 patients, a transbrachial approach was used. Under ultrasound guidance, the left brachial artery was punctured. After having placed the tip of the angiography catheter at the level of L4 to check the aortic bifurcation, the uterine arteries were catheterised and embolized with calibrated particles. Data concerning exposure to radiation and the duration of the intervention were recorded for comparison between the two groups of subjects. Clinical controls and magnetic resonance imaging were complemented with echo-colour Doppler of the brachial artery to confirm the integrity and function of the vessel., Results: The uterine arteries were catheterised easily in a mean time of 25″, compared to 72″ using the femoral approach. As far as exposure to radiation was concerned, the mean fluoroscopy time for the femoral approach was 21.7' [range 14.4-42.7'] compared to 17.6' [range 7.7-25.5'] for the transbrachial approach. The time of occupation of the angiography suite was 118' (range 95-155') with the femoral approach, compared to 92' (range 65-123') with the transbrachial approach. No immediate complications involving the brachial artery were recorded., Discussion: In the treatment of symptomatic uterine fibromas, embolization of the uterine arteries performed via a transbrachial approach was shown to be safe and technically valid with regard to reducing the overall time of the intervention, ease of selective catheterisation, and shorter times spent in hospital, as well as being better accepted by patients.
- Published
- 2015
- Full Text
- View/download PDF
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